Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr15 67473692 . G A CCDS10222.1:NM_005902.3:c.772Gat>Aat_NP_005893.1:p.258D>N Homo sapiens SMAD family member 3 (SMAD3), transcript variant 1, mRNA.
pdb_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1khx 1 Q15796 92.51 1e-157 X-RAY
 2002-02-06 ASP A:60 A:300 5.0 0.033 E -125.2 178.0 5.0 0.033 0.0 HOH
 4.432
 CB
 O
6zvq 1 Q15796 92.51 1e-157 X-RAY
 2021-06-09 ASP A:60 A:300 5.0 0.033 E -129.6 178.2 5.0 0.033 0.0 GOL
HOH
 7.003
3.195
 OD2
OD1
 O1
O
1mk2 1 P84022 100.0 4e-154 X-RAY
 2002-10-16 ASP A:39 A:257 4.0 0.027 E -121.9 -173.7 4.0 0.027 0.0
6m64 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 ASP A:41 A:300 6.0 0.04 E -133.4 179.2 6.0 0.04 0.0 HOH
 2.695
 OD2
 O
ASP C:41 C:300 7.0 0.047 E -129.6 178.0 7.0 0.047 0.0 HOH
 2.529
 OD2
 O
ASP E:41 E:300 6.0 0.04 E -136.6 177.9 6.0 0.04 0.0 HOH
 2.719
 OD2
 O
7co1 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 ASP A:41 A:300 4.0 0.027 -113.3 176.3 4.0 0.027 0.0
ASP C:41 C:300 5.0 0.033 -113.3 177.3 5.0 0.033 0.0
ASP E:41 E:300 4.0 0.027 -113.6 176.8 4.0 0.027 0.0
1u7f 1 P84022 100.0 2e-147 X-RAY
 2004-09-28 ASP A:31 A:258 4.0 0.027 E -123.3 -177.3 4.0 0.027 0.0 HOH
 2.998
 CB
 O
ASP C:31 C:258 4.0 0.027 E -125.7 -174.9 4.0 0.027 0.0 HOH
 6.968
 OD2
 O
5xoc 1 P84022 100.0 2e-147 X-RAY
 2018-03-28 ASP A:41 A:258 5.0 0.033 E -132.3 176.9 5.0 0.033 0.0 HOH
 3.493
 OD2
 O
1mjs 1 P84022 100.0 9e-147 X-RAY
 2002-10-16 ASP A:30 A:257 11.0 0.073 E -132.9 174.2 11.0 0.073 0.0 HOH
 2.402
 OD1
 O
1u7v 1 Q15796 96.97 6e-145 X-RAY
 2004-09-28 ASP A:31 A:300 5.0 0.033 E -114.5 179.1 5.0 0.033 0.0
ASP B:31 C:300 4.0 0.027 E -115.5 -174.8 4.0 0.027 0.0
5xod 1 Q15796 97.46 3e-144 X-RAY
 2018-03-28 ASP A:41 A:300 7.0 0.047 E -132.2 179.2 7.0 0.047 0.0 HOH
 5.655
 C
 O
5zoj 1 Q15796 97.46 4e-144 X-RAY
 2018-10-10 ASP A:42 A:300 4.0 0.027 E -118.4 177.0 4.0 0.027 0.0
ASP B:42 B:300 5.0 0.033 E -120.1 177.8 5.0 0.033 0.0
ASP C:42 C:300 4.0 0.027 E -120.1 177.2 4.0 0.027 0.0
1dev 1 Q15796 97.45 9e-144 X-RAY
 2000-01-21 ASP A:40 A:300 5.0 0.033 E -135.2 176.5 5.0 0.033 0.0
ASP C:40 C:300 5.0 0.033 E -134.3 178.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p84022-f1 1 P84022 100.0 0.0 ASP A:258 A:258 4.0 0.027 E -133.8 168.3
af-q15796-f1 1 Q15796 83.73 0.0 ASP A:300 A:300 4.0 0.027 E -130.6 169.0