Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr15 67473700 . C A CCDS10222.1:NM_005902.3:c.780ttC>ttA_NP_005893.1:p.260F>L Homo sapiens SMAD family member 3 (SMAD3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1khx 1 Q15796 92.51 1e-157 X-RAY
 2002-02-06 PHE A:62 A:302 95.0 0.452 S -90.1 -159.0 18.0 0.086 0.366 A:Q15796:0.367
 HOH
 3.787
 CZ
 O
6zvq 1 Q15796 92.51 1e-157 X-RAY
 2021-06-09 PHE A:62 A:302 91.0 0.433 S -104.2 -154.8 15.0 0.071 0.362 A:Q15796:0.362
 GOL
TAR
HOH
 6.632
8.252
3.875
 O
O
CZ
 O2
O1
O
1mk2 1 P84022 100.0 4e-154 X-RAY
 2002-10-16 PHE A:41 A:259 85.0 0.405 -69.0 146.3 85.0 0.405 0.0
6m64 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 PHE A:43 A:302 96.0 0.457 S -98.6 -156.8 25.0 0.119 0.338 C:Q15796:0.338
 HOH
 3.690
 CE2
 O
PHE C:43 C:302 98.0 0.467 S -96.7 -159.2 27.0 0.129 0.338 E:Q15796:0.338
 HOH
 3.495
 CE1
 O
PHE E:43 E:302 97.0 0.462 S -97.9 -158.1 21.0 0.1 0.362 A:Q15796:0.362
 HOH
 3.220
 CE1
 O
7co1 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 PHE A:43 A:302 92.0 0.438 S -95.9 -163.0 15.0 0.071 0.367 C:Q15796:0.367
PHE C:43 C:302 97.0 0.462 S -95.1 -162.7 24.0 0.114 0.348 E:Q15796:0.348
PHE E:43 E:302 92.0 0.438 S -95.8 -162.3 18.0 0.086 0.352 A:Q15796:0.352
1u7f 1 P84022 100.0 2e-147 X-RAY
 2004-09-28 PHE A:33 A:260 91.0 0.433 S -92.1 -166.3 18.0 0.086 0.347 C:P84022:0.348
 HOH
 3.011
 CE1
 O
PHE C:33 C:260 85.0 0.405 S -97.0 180.0 24.0 0.114 0.291 B:Q13485:0.29
 HOH
 5.617
 CZ
 O
5xoc 1 P84022 100.0 2e-147 X-RAY
 2018-03-28 PHE A:43 A:260 96.0 0.457 S -97.3 -163.2 18.0 0.086 0.371 A:P84022:0.371
 HOH
 4.673
 CE2
 O
1mjs 1 P84022 100.0 9e-147 X-RAY
 2002-10-16 PHE A:32 A:259 87.0 0.414 -77.0 156.0 87.0 0.414 0.0 HOH
 3.484
 CE1
 O
1u7v 1 Q15796 96.97 6e-145 X-RAY
 2004-09-28 PHE A:33 A:302 90.0 0.429 S -93.3 -162.4 18.0 0.086 0.343 B:Q15796:0.343
PHE B:33 C:302 86.0 0.41 S -97.9 -174.4 21.0 0.1 0.31 C:Q13485:0.31
5xod 1 Q15796 97.46 3e-144 X-RAY
 2018-03-28 PHE A:43 A:302 75.0 0.357 S -98.6 -162.9 3.0 0.014 0.343 A:Q15796:0.343
 HOH
 4.743
 CE1
 O
5zoj 1 Q15796 97.46 4e-144 X-RAY
 2018-10-10 PHE A:44 A:302 98.0 0.467 S -94.1 -162.0 29.0 0.138 0.329 B:Q15796:0.329
PHE B:44 B:302 97.0 0.462 S -93.3 -161.4 21.0 0.1 0.362 C:Q15796:0.362
PHE C:44 C:302 95.0 0.452 S -93.6 -161.3 26.0 0.124 0.328 A:Q15796:0.329
1dev 1 Q15796 97.45 9e-144 X-RAY
 2000-01-21 PHE A:42 A:302 82.0 0.39 -72.3 157.9 82.0 0.39 0.0
PHE C:42 C:302 84.0 0.4 -80.6 163.0 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p84022-f1 1 P84022 100.0 0.0 PHE A:260 A:260 100.0 0.476 S -92.3 -165.4
af-q15796-f1 1 Q15796 83.73 0.0 PHE A:302 A:302 97.0 0.462 S -90.8 -166.8