Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr15 67473702 . C A CCDS10222.1:NM_005902.3:c.782aCc>aAc_NP_005893.1:p.261T>N Homo sapiens SMAD family member 3 (SMAD3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1khx 1 Q15796 92.51 1e-157 X-RAY
 2002-02-06 THR A:63 A:303 94.0 0.671 -130.4 22.2 0.0 0.0 0.671 A:Q15796:0.671
 HOH
 5.968
 CG2
 O
6zvq 1 Q15796 92.51 1e-157 X-RAY
 2021-06-09 THR A:63 A:303 92.0 0.657 -142.7 30.5 0.0 0.0 0.657 A:Q15796:0.657
 GOL
TAR
HOH
 6.402
6.833
6.464
 C
CG2
CG2
 O1
O2
O
1mk2 1 P84022 100.0 4e-154 X-RAY
 2002-10-16 THR A:42 A:260 97.0 0.693 S -84.6 40.9 97.0 0.693 0.0
6m64 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 THR A:44 A:303 94.0 0.671 -138.5 15.3 0.0 0.0 0.671 C:Q15796:0.671
 HOH
 5.893
 C
 O
THR C:44 C:303 95.0 0.679 -135.3 13.7 1.0 0.007 0.672 E:Q15796:0.671
 HOH
 5.187
 CG2
 O
THR E:44 E:303 96.0 0.686 -137.0 11.5 0.0 0.0 0.686 A:Q15796:0.686
 HOH
 5.841
 C
 O
7co1 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 THR A:44 A:303 98.0 0.7 -130.3 28.1 0.0 0.0 0.7 C:Q15796:0.7
THR C:44 C:303 98.0 0.7 -130.5 27.7 1.0 0.007 0.693 E:Q15796:0.693
THR E:44 E:303 99.0 0.707 -129.3 27.3 0.0 0.0 0.707 A:Q15796:0.707
1u7f 1 P84022 100.0 2e-147 X-RAY
 2004-09-28 THR A:34 A:261 94.0 0.671 -121.6 25.3 0.0 0.0 0.671 C:P84022:0.671
 HOH
 6.099
 C
 O
THR C:34 C:261 94.0 0.671 -112.7 29.9 0.0 0.0 0.671 B:Q13485:0.671
 HOH
 5.608
 C
 O
5xoc 1 P84022 100.0 2e-147 X-RAY
 2018-03-28 THR A:44 A:261 94.0 0.671 -130.6 24.2 0.0 0.0 0.671 A:P84022:0.671
 HOH
 7.374
 O
 O
1mjs 1 P84022 100.0 9e-147 X-RAY
 2002-10-16 THR A:33 A:260 96.0 0.686 S -88.7 30.0 96.0 0.686 0.0 HOH
 2.949
 O
 O
1u7v 1 Q15796 96.97 6e-145 X-RAY
 2004-09-28 THR A:34 A:303 95.0 0.679 -123.8 20.8 0.0 0.0 0.679 B:Q15796:0.679
THR B:34 C:303 93.0 0.664 -118.4 29.0 0.0 0.0 0.664 C:Q13485:0.664
5xod 1 Q15796 97.46 3e-144 X-RAY
 2018-03-28 THR A:44 A:303 99.0 0.707 -133.2 31.5 0.0 0.0 0.707 A:Q15796:0.707
 HOH
 6.323
 C
 O
5zoj 1 Q15796 97.46 4e-144 X-RAY
 2018-10-10 THR A:45 A:303 97.0 0.693 -134.9 36.8 0.0 0.0 0.693 B:Q15796:0.693
THR B:45 B:303 98.0 0.7 -134.1 36.7 0.0 0.0 0.7 C:Q15796:0.7
THR C:45 C:303 97.0 0.693 -134.7 36.6 4.0 0.029 0.664 A:Q15796:0.664
1dev 1 Q15796 97.45 9e-144 X-RAY
 2000-01-21 THR A:43 A:303 86.0 0.614 -94.8 18.0 86.0 0.614 0.0
THR C:43 C:303 92.0 0.657 -96.7 16.2 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p84022-f1 1 P84022 100.0 0.0 THR A:261 A:261 98.0 0.7 -133.1 32.5
af-q15796-f1 1 Q15796 83.73 0.0 THR A:303 A:303 96.0 0.686 -131.3 28.3