Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr15 67473722 . C A CCDS10222.1:NM_005902.3:c.802Cgc>Agc_NP_005893.1:p.268R>S Homo sapiens SMAD family member 3 (SMAD3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1khx 1 Q15796 92.51 1e-157 X-RAY
 2002-02-06 ARG A:70 A:310 72.0 0.32 E -137.4 125.4 29.0 0.129 0.191 A:Q15796:0.191
 HOH
 2.873
 O
 O
6zvq 1 Q15796 92.51 1e-157 X-RAY
 2021-06-09 ARG A:70 A:310 69.0 0.307 E -135.4 120.1 20.0 0.089 0.218 A:Q15796:0.218
 GOL
GOL
TAR
HOH
 3.142
7.067
6.888
2.720
 O
N
O
O
 O1
O3
O11
O
1mk2 1 P84022 100.0 4e-154 X-RAY
 2002-10-16 ARG A:49 A:267 64.0 0.284 E -162.5 119.0 64.0 0.284 0.0 ACY
 5.755
 O
 CH3
6m64 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 ARG A:51 A:310 71.0 0.316 E -132.6 120.2 38.0 0.169 0.147 C:Q15796:0.147
 HOH
 2.860
 NH1
 O
ARG C:51 C:310 75.0 0.333 E -131.5 127.0 19.0 0.084 0.249 E:Q15796:0.249
 HOH
 2.773
 O
 O
ARG E:51 E:310 71.0 0.316 E -134.5 122.4 18.0 0.08 0.236 A:Q15796:0.236
 HOH
 2.831
 O
 O
7co1 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 ARG A:51 A:310 75.0 0.333 B -128.0 127.2 34.0 0.151 0.182 C:Q15796:0.182
ARG C:51 C:310 72.0 0.32 B -129.9 127.3 20.0 0.089 0.231 E:Q15796:0.231
ARG E:51 E:310 71.0 0.316 B -128.5 126.5 36.0 0.16 0.156 A:Q15796:0.156
1u7f 1 P84022 100.0 2e-147 X-RAY
 2004-09-28 ARG A:41 A:268 69.0 0.307 E -129.0 119.2 39.0 0.173 0.134 C:P84022:0.133
 HOH
 2.591
 O
 O
ARG C:41 C:268 72.0 0.32 E -149.1 107.7 42.0 0.187 0.133 B:Q13485:0.133
 HOH
 2.548
 O
 O
5xoc 1 P84022 100.0 2e-147 X-RAY
 2018-03-28 ARG A:51 A:268 67.0 0.298 E -134.0 128.7 41.0 0.182 0.116 A:P84022:0.116
 HOH
 3.451
 O
 O
1mjs 1 P84022 100.0 9e-147 X-RAY
 2002-10-16 ARG A:40 A:267 75.0 0.333 E -155.7 135.7 75.0 0.333 0.0 HOH
 2.968
 CD
 O
1u7v 1 Q15796 96.97 6e-145 X-RAY
 2004-09-28 ARG A:41 A:310 70.0 0.311 E -131.7 125.0 43.0 0.191 0.12 B:Q15796:0.12
ARG B:41 C:310 70.0 0.311 E -145.3 106.5 41.0 0.182 0.129 C:Q13485:0.129
5xod 1 Q15796 97.46 3e-144 X-RAY
 2018-03-28 ARG A:51 A:310 69.0 0.307 E -135.5 126.4 21.0 0.093 0.214 A:Q15796:0.213
 HOH
 2.895
 NH1
 O
5zoj 1 Q15796 97.46 4e-144 X-RAY
 2018-10-10 ARG A:52 A:310 69.0 0.307 E -123.7 131.8 40.0 0.178 0.129 B:Q15796:0.129
ARG B:52 B:310 67.0 0.298 E -123.5 132.5 40.0 0.178 0.12 C:Q15796:0.12
ARG C:52 C:310 68.0 0.302 E -124.1 132.6 43.0 0.191 0.111 A:Q15796:0.111
1dev 1 Q15796 97.45 9e-144 X-RAY
 2000-01-21 ARG A:50 A:310 63.0 0.28 E -141.8 124.0 63.0 0.28 0.0
ARG C:50 C:310 59.0 0.262 E -143.5 121.0 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p84022-f1 1 P84022 100.0 0.0 ARG A:268 A:268 63.0 0.28 E -135.5 114.8
af-q15796-f1 1 Q15796 83.73 0.0 ARG A:310 A:310 66.0 0.293 E -131.5 117.7