Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr15 67473768 . T A CCDS10222.1:NM_005902.3:c.848gTg>gAg_NP_005893.1:p.283V>E Homo sapiens SMAD family member 3 (SMAD3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1khx 1 Q15796 92.51 1e-157 X-RAY
 2002-02-06 VAL A:85 A:325 0.0 0.0 H -64.5 -46.6 0.0 0.0 0.0 HOH
 3.606
 CG2
 O
6zvq 1 Q15796 92.51 1e-157 X-RAY
 2021-06-09 VAL A:85 A:325 5.0 0.032 H -65.8 -43.7 5.0 0.032 0.0 GOL
TAR
HOH
 6.899
8.965
3.251
 CG1
CG1
CG2
 H32
O1
O
1mk2 1 P84022 100.0 4e-154 X-RAY
 2002-10-16 VAL A:64 A:282 2.0 0.013 H -59.3 -59.9 2.0 0.013 0.0
6m64 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 VAL A:66 A:325 2.0 0.013 H -65.3 -42.7 2.0 0.013 0.0 HOH
 3.562
 CG2
 O
VAL C:66 C:325 2.0 0.013 H -66.0 -44.9 2.0 0.013 0.0 HOH
 3.689
 CG2
 O
VAL E:66 E:325 2.0 0.013 H -66.2 -42.8 2.0 0.013 0.0 HOH
 3.461
 CG2
 O
7co1 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 VAL A:66 A:325 1.0 0.006 H -65.9 -40.5 1.0 0.006 0.0
VAL C:66 C:325 1.0 0.006 H -66.1 -41.2 1.0 0.006 0.0
VAL E:66 E:325 0.0 0.0 H -65.9 -39.0 0.0 0.0 0.0
1u7f 1 P84022 100.0 2e-147 X-RAY
 2004-09-28 VAL A:56 A:283 1.0 0.006 H -58.7 -47.6 1.0 0.006 0.0 HOH
 4.009
 CG2
 O
VAL C:56 C:283 4.0 0.026 H -48.7 -51.5 4.0 0.026 0.0 HOH
 7.550
 CG1
 O
5xoc 1 P84022 100.0 2e-147 X-RAY
 2018-03-28 VAL A:66 A:283 3.0 0.019 H -60.3 -42.8 3.0 0.019 0.0 HOH
 5.051
 CG2
 O
1mjs 1 P84022 100.0 9e-147 X-RAY
 2002-10-16 VAL A:55 A:282 2.0 0.013 H -67.7 -42.8 2.0 0.013 0.0 HOH
 3.573
 CG2
 O
1u7v 1 Q15796 96.97 6e-145 X-RAY
 2004-09-28 VAL A:56 A:325 0.0 0.0 H -65.1 -50.2 0.0 0.0 0.0
VAL B:56 C:325 1.0 0.006 H -55.4 -53.2 1.0 0.006 0.0
5xod 1 Q15796 97.46 3e-144 X-RAY
 2018-03-28 VAL A:66 A:325 3.0 0.019 H -67.2 -41.0 3.0 0.019 0.0 HOH
 3.619
 CG2
 O
5zoj 1 Q15796 97.46 4e-144 X-RAY
 2018-10-10 VAL A:67 A:325 2.0 0.013 H -64.7 -41.6 2.0 0.013 0.0
VAL B:67 B:325 3.0 0.019 H -64.9 -43.1 3.0 0.019 0.0
VAL C:67 C:325 3.0 0.019 H -62.9 -41.2 3.0 0.019 0.0
1dev 1 Q15796 97.45 9e-144 X-RAY
 2000-01-21 VAL A:65 A:325 1.0 0.006 H -59.5 -43.6 1.0 0.006 0.0
VAL C:65 C:325 2.0 0.013 H -58.4 -43.0 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p84022-f1 1 P84022 100.0 0.0 VAL A:283 A:283 2.0 0.013 H -67.8 -47.8
af-q15796-f1 1 Q15796 83.73 0.0 VAL A:325 A:325 2.0 0.013 H -64.2 -46.8