Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr15 67473771 . A C CCDS10222.1:NM_005902.3:c.851gAg>gCg_NP_005893.1:p.284E>A Homo sapiens SMAD family member 3 (SMAD3), transcript variant 1, mRNA.
pdb_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1khx 1 Q15796 92.51 1e-157 X-RAY
 2002-02-06 GLU A:86 A:326 55.0 0.289 H -55.6 -48.4 41.0 0.216 0.073 A:Q15796:0.074
 HOH
 2.560
 OE1
 O
6zvq 1 Q15796 92.51 1e-157 X-RAY
 2021-06-09 GLU A:86 A:326 61.0 0.321 H -62.7 -42.5 44.0 0.232 0.089 A:Q15796:0.089
 GOL
TAR
HOH
 2.799
4.935
2.788
 OE2
OE2
OE2
 HO3
O11
O
1mk2 1 P84022 100.0 4e-154 X-RAY
 2002-10-16 GLU A:65 A:283 78.0 0.411 H -53.6 -46.3 78.0 0.411 0.0
6m64 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 GLU A:67 A:326 83.0 0.437 H -59.2 -42.9 83.0 0.437 0.0 HOH
 3.120
 OE2
 O
GLU C:67 C:326 107.0 0.563 H -56.3 -42.8 70.0 0.368 0.195 E:Q15796:0.195
 HOH
 2.694
 O
 O
GLU E:67 E:326 68.0 0.358 H -58.4 -43.9 34.0 0.179 0.179 A:Q15796:0.179
 HOH
 2.473
 OE2
 O
7co1 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 GLU A:67 A:326 66.0 0.347 H -59.9 -40.5 30.0 0.158 0.189 C:Q15796:0.189
GLU C:67 C:326 65.0 0.342 H -61.3 -38.2 42.0 0.221 0.121 E:Q15796:0.121
GLU E:67 E:326 71.0 0.374 H -59.1 -38.8 39.0 0.205 0.169 A:Q15796:0.168
1u7f 1 P84022 100.0 2e-147 X-RAY
 2004-09-28 GLU A:57 A:284 73.0 0.384 H -62.4 -28.4 56.0 0.295 0.089 C:P84022:0.089
 HOH
 2.218
 OE2
 O
GLU C:57 C:284 116.0 0.611 H -58.2 -42.1 44.0 0.232 0.379 B:Q13485:0.379
 HOH
 2.270
 OE1
 O
5xoc 1 P84022 100.0 2e-147 X-RAY
 2018-03-28 GLU A:67 A:284 52.0 0.274 H -60.3 -44.4 46.0 0.242 0.032 B:P0AA25+O75593:0.032
 HOH
 7.505
 O
 O
1mjs 1 P84022 100.0 9e-147 X-RAY
 2002-10-16 GLU A:56 A:283 77.0 0.405 H -66.2 -29.5 77.0 0.405 0.0 HOH
 2.455
 OE1
 O
1u7v 1 Q15796 96.97 6e-145 X-RAY
 2004-09-28 GLU A:57 A:326 74.0 0.389 H -55.3 -31.6 57.0 0.3 0.089 B:Q15796:0.089
GLU B:57 C:326 119.0 0.626 H -55.0 -42.4 44.0 0.232 0.394 C:Q13485:0.395
5xod 1 Q15796 97.46 3e-144 X-RAY
 2018-03-28 GLU A:67 A:326 84.0 0.442 H -58.7 -44.7 73.0 0.384 0.058 A:Q15796:0.058
 HOH
 6.605
 N
 O
5zoj 1 Q15796 97.46 4e-144 X-RAY
 2018-10-10 GLU A:68 A:326 65.0 0.342 H -57.9 -44.3 56.0 0.295 0.047 B:Q15796:0.047
GLU B:68 B:326 68.0 0.358 H -58.9 -44.5 57.0 0.3 0.058 C:Q15796:0.058
GLU C:68 C:326 92.0 0.484 H -57.8 -43.6 90.0 0.474 0.01 A:Q15796:0.011
1dev 1 Q15796 97.45 9e-144 X-RAY
 2000-01-21 GLU A:66 A:326 97.0 0.511 H -59.0 -37.8 97.0 0.511 0.0
GLU C:66 C:326 120.0 0.632 H -60.2 -45.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p84022-f1 1 P84022 100.0 0.0 GLU A:284 A:284 87.0 0.458 H -56.3 -47.4
af-q15796-f1 1 Q15796 83.73 0.0 GLU A:326 A:326 89.0 0.468 H -60.8 -41.2