Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr15 67473779 . C A CCDS10222.1:NM_005902.3:c.859Cgg>Agg_NP_005893.1:p.287R>R Homo sapiens SMAD family member 3 (SMAD3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1khx 1 Q15796 92.51 1e-157 X-RAY
 2002-02-06 ARG A:89 A:329 27.0 0.12 H -56.7 -30.3 7.0 0.031 0.089 A:Q15796:0.089
 HOH
 2.737
 NH2
 O
6zvq 1 Q15796 92.51 1e-157 X-RAY
 2021-06-09 ARG A:89 A:329 23.0 0.102 H -55.0 -36.8 6.0 0.027 0.075 A:Q15796:0.076
 GOL
GOL
GOL
TAR
HOH
 9.228
5.460
7.749
3.302
2.669
 NH1
NE
NH2
NH2
NE
 O2
H31
O1
O1
O
1mk2 1 P84022 100.0 4e-154 X-RAY
 2002-10-16 ARG A:68 A:286 28.0 0.124 H -53.3 -20.1 28.0 0.124 0.0
6m64 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 ARG A:70 A:329 27.0 0.12 H -59.5 -31.8 8.0 0.036 0.084 C:Q15796:0.084
 HOH
 2.776
 O
 O
ARG C:70 C:329 32.0 0.142 H -61.6 -31.5 14.0 0.062 0.08 E:Q15796:0.08
 HOH
 2.727
 O
 O
ARG E:70 E:329 27.0 0.12 H -60.4 -31.5 7.0 0.031 0.089 A:Q15796:0.089
 HOH
 2.706
 O
 O
7co1 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 ARG A:70 A:329 23.0 0.102 H -68.1 -15.9 3.0 0.013 0.089 C:Q15796:0.089
ARG C:70 C:329 27.0 0.12 H -69.0 -15.8 7.0 0.031 0.089 E:Q15796:0.089
ARG E:70 E:329 30.0 0.133 T -68.2 -15.3 6.0 0.027 0.106 A:Q15796:0.107
1u7f 1 P84022 100.0 2e-147 X-RAY
 2004-09-28 ARG A:60 A:287 34.0 0.151 G -73.4 -17.8 9.0 0.04 0.111 C:P84022:0.111
 HOH
 2.495
 NH1
 O
ARG C:60 C:287 37.0 0.164 H -55.6 -37.4 6.0 0.027 0.137 B:Q13485:0.138
 HOH
 5.957
 NH1
 O
5xoc 1 P84022 100.0 2e-147 X-RAY
 2018-03-28 ARG A:70 A:287 18.0 0.08 H -55.0 -35.6 15.0 0.067 0.013 A:P84022:0.013
 HOH
 2.833
 O
 O
1mjs 1 P84022 100.0 9e-147 X-RAY
 2002-10-16 ARG A:59 A:286 30.0 0.133 H -51.5 -35.4 30.0 0.133 0.0 HOH
 2.748
 NE
 O
1u7v 1 Q15796 96.97 6e-145 X-RAY
 2004-09-28 ARG A:60 A:329 30.0 0.133 T -68.0 -17.5 7.0 0.031 0.102 B:Q15796:0.102
ARG B:60 C:329 26.0 0.116 H -61.4 -31.4 2.0 0.009 0.107 C:Q13485:0.107
5xod 1 Q15796 97.46 3e-144 X-RAY
 2018-03-28 ARG A:70 A:329 24.0 0.107 H -58.7 -37.9 7.0 0.031 0.076 A:Q15796:0.076
 HOH
 2.774
 O
 O
5zoj 1 Q15796 97.46 4e-144 X-RAY
 2018-10-10 ARG A:71 A:329 19.0 0.084 H -69.7 -23.3 4.0 0.018 0.066 B:Q15796:0.067
ARG B:71 B:329 29.0 0.129 H -71.3 -20.8 8.0 0.036 0.093 C:Q15796:0.093
ARG C:71 C:329 44.0 0.196 H -72.0 -21.9 23.0 0.102 0.094 A:Q15796:0.093
1dev 1 Q15796 97.45 9e-144 X-RAY
 2000-01-21 ARG A:69 A:329 34.0 0.151 H -60.9 -35.0 34.0 0.151 0.0
ARG C:69 C:329 22.0 0.098 H -57.6 -39.4 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p84022-f1 1 P84022 100.0 0.0 ARG A:287 A:287 27.0 0.12 H -55.6 -41.1
af-q15796-f1 1 Q15796 83.73 0.0 ARG A:329 A:329 24.0 0.107 H -55.8 -38.5