Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr15 67477084 . C A CCDS10222.1:NM_005902.3:c.891taC>taA_NP_005893.1:p.297Y>* Homo sapiens SMAD family member 3 (SMAD3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1khx 1 Q15796 92.51 1e-157 X-RAY
 2002-02-06 TYR A:99 A:339 42.0 0.183 E -154.9 161.0 42.0 0.183 0.0 HOH
 2.649
 OH
 O
6zvq 1 Q15796 92.51 1e-157 X-RAY
 2021-06-09 TYR A:99 A:339 46.0 0.2 E -152.1 160.5 46.0 0.2 0.0 GOL
TAR
GOL
GOL
HOH
 3.891
9.115
9.834
6.550
4.049
 CZ
OH
C
OH
OH
 C3
O11
C3
HO3
O
1mk2 1 P84022 100.0 4e-154 X-RAY
 2002-10-16 TYR A:78 A:296 69.0 0.3 E -128.8 139.2 25.0 0.109 0.191 B:O95405:0.191
6m64 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 TYR A:80 A:339 43.0 0.187 E -149.8 148.1 43.0 0.187 0.0 HOH
 3.166
 OH
 O
TYR C:80 C:339 36.0 0.157 E -145.8 149.6 36.0 0.157 0.0 HOH
 3.729
 CD2
 O
TYR E:80 E:339 42.0 0.183 E -146.6 152.6 42.0 0.183 0.0 HOH
 5.766
 CE2
 O
7co1 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 TYR A:80 A:339 51.0 0.222 E -125.3 148.0 51.0 0.222 0.0
TYR C:80 C:339 51.0 0.222 E -124.2 149.4 51.0 0.222 0.0
TYR E:80 E:339 39.0 0.17 E -123.1 150.0 39.0 0.17 0.0
1u7f 1 P84022 100.0 2e-147 X-RAY
 2004-09-28 TYR A:70 A:297 67.0 0.291 E -123.5 143.0 67.0 0.291 0.0 HOH
 3.463
 CD2
 O
TYR C:70 C:297 69.0 0.3 E -160.7 135.9 69.0 0.3 0.0 HOH
 3.688
 CE1
 O
5xoc 1 P84022 100.0 2e-147 X-RAY
 2018-03-28 TYR A:80 A:297 27.0 0.117 E -146.3 160.2 27.0 0.117 0.0 HOH
 7.196
 CE1
 O
1mjs 1 P84022 100.0 9e-147 X-RAY
 2002-10-16 TYR A:69 A:296 77.0 0.335 E -127.9 135.0 77.0 0.335 0.0 HOH
 3.871
 CE1
 O
1u7v 1 Q15796 96.97 6e-145 X-RAY
 2004-09-28 TYR A:70 A:339 71.0 0.309 E -118.0 147.5 71.0 0.309 0.0
TYR B:70 C:339 73.0 0.317 E -161.0 132.7 73.0 0.317 0.0
5xod 1 Q15796 97.46 3e-144 X-RAY
 2018-03-28 TYR A:80 A:339 36.0 0.157 E -155.4 156.7 36.0 0.157 0.0 HOH
 9.336
 C
 O
5zoj 1 Q15796 97.46 4e-144 X-RAY
 2018-10-10 TYR A:81 A:339 63.0 0.274 E -135.3 147.0 63.0 0.274 0.0
TYR B:81 B:339 67.0 0.291 E -134.4 148.3 67.0 0.291 0.0
TYR C:81 C:339 87.0 0.378 E -133.4 141.6 87.0 0.378 0.0
1dev 1 Q15796 97.45 9e-144 X-RAY
 2000-01-21 TYR A:79 A:339 48.0 0.209 E -125.3 143.2 27.0 0.117 0.092 B:O95405:0.091
TYR C:79 C:339 63.0 0.274 E -127.2 140.9 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p84022-f1 1 P84022 100.0 0.0 TYR A:297 A:297 4.0 0.017 E -142.4 137.9
af-q15796-f1 1 Q15796 83.73 0.0 TYR A:339 A:339 4.0 0.017 E -138.1 137.9