Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr15 67477184 . G A CCDS10222.1:NM_005902.3:c.991Gtc>Atc_NP_005893.1:p.331V>I Homo sapiens SMAD family member 3 (SMAD3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1khx 1 Q15796 92.51 1e-157 X-RAY
 2002-02-06 VAL A:133 A:373 25.0 0.161 -116.4 121.7 25.0 0.161 0.0 HOH
 2.679
 CG2
 O
6zvq 1 Q15796 92.51 1e-157 X-RAY
 2021-06-09 VAL A:133 A:373 31.0 0.2 -115.7 123.5 31.0 0.2 0.0 SO4
TAR
GOL
HOH
 5.365
9.999
2.894
3.154
 CG2
O
O
N
 O4
O41
H31
O
1mk2 1 P84022 100.0 4e-154 X-RAY
 2002-10-16 VAL A:112 A:330 16.0 0.103 -125.3 122.7 13.0 0.084 0.019 B:O95405:0.019
 ACY
ACY
 7.183
5.529
 N
CG2
 OXT
O
6m64 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 VAL A:114 A:373 32.0 0.206 -110.1 120.6 32.0 0.206 0.0 HOH
 2.758
 O
 O
VAL C:114 C:373 32.0 0.206 -116.0 118.5 32.0 0.206 0.0 HOH
 2.932
 O
 O
VAL E:114 E:373 23.0 0.148 -104.0 122.8 23.0 0.148 0.0 HOH
 2.870
 O
 O
7co1 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 VAL A:114 A:373 32.0 0.206 -116.6 124.1 32.0 0.206 0.0
VAL C:114 C:373 36.0 0.232 -116.6 124.4 36.0 0.232 0.0
VAL E:114 E:373 31.0 0.2 -115.3 122.7 31.0 0.2 0.0
1u7f 1 P84022 100.0 2e-147 X-RAY
 2004-09-28 VAL A:104 A:331 21.0 0.135 -109.1 118.4 21.0 0.135 0.0 HOH
 2.927
 N
 O
VAL C:104 C:331 22.0 0.142 -94.5 130.0 22.0 0.142 0.0 HOH
 2.770
 CG2
 O
5xoc 1 P84022 100.0 2e-147 X-RAY
 2018-03-28 VAL A:114 A:331 37.0 0.239 -96.2 121.1 0.0 0.0 0.239 B:P0AA25+O75593:0.239
 HOH
 2.786
 O
 O
1mjs 1 P84022 100.0 9e-147 X-RAY
 2002-10-16 VAL A:103 A:330 42.0 0.271 -108.5 121.6 42.0 0.271 0.0 HOH
 3.970
 O
 O
1u7v 1 Q15796 96.97 6e-145 X-RAY
 2004-09-28 VAL A:104 A:373 30.0 0.194 -109.6 118.1 30.0 0.194 0.0
VAL B:104 C:373 25.0 0.161 -99.9 131.8 25.0 0.161 0.0
5xod 1 Q15796 97.46 3e-144 X-RAY
 2018-03-28 VAL A:114 A:373 32.0 0.206 E -107.9 125.7 32.0 0.206 0.0 HOH
 9.048
 CG1
 O
5zoj 1 Q15796 97.46 4e-144 X-RAY
 2018-10-10 VAL A:115 A:373 13.0 0.084 -99.6 133.2 5.0 0.032 0.052 D:Q9Y2U8:0.052
VAL B:115 B:373 15.0 0.097 -100.2 133.0 2.0 0.013 0.084 E:Q9Y2U8:0.084
VAL C:115 C:373 27.0 0.174 -100.9 136.7 27.0 0.174 0.0
1dev 1 Q15796 97.45 9e-144 X-RAY
 2000-01-21 VAL A:113 A:373 19.0 0.123 -119.1 122.3 14.0 0.09 0.033 B:O95405:0.032
VAL C:113 C:373 3.0 0.019 -105.0 116.9 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p84022-f1 1 P84022 100.0 0.0 VAL A:331 A:331 22.0 0.142 -114.6 104.1
af-q15796-f1 1 Q15796 83.73 0.0 VAL A:373 A:373 21.0 0.135 -111.3 109.4