Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr15 67479832 . G A CCDS10222.1:NM_005902.3:c.1139tGg>tAg_NP_005893.1:p.380W>* Homo sapiens SMAD family member 3 (SMAD3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1khx 1 Q15796 92.51 1e-157 X-RAY
 2002-02-06 TRP A:182 A:422 5.0 0.02 -152.2 165.3 5.0 0.02 0.0 HOH
 2.740
 O
 O
6zvq 1 Q15796 92.51 1e-157 X-RAY
 2021-06-09 TRP A:182 A:422 10.0 0.039 -155.3 161.8 10.0 0.039 0.0 SO4
GOL
HOH
 3.157
6.572
4.431
 NE1
O
O
 O4
H2
O
1mk2 1 P84022 100.0 4e-154 X-RAY
 2002-10-16 TRP A:161 A:379 2.0 0.008 -139.7 -176.4 1.0 0.004 0.004 A:P84022:0.004
 ACY
ACY
ACY
 9.254
2.842
9.452
 CZ2
NE1
C
 O
O
O
6m64 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 TRP A:163 A:422 10.0 0.039 -145.9 165.4 10.0 0.039 0.0 HOH
 3.291
 NE1
 O
TRP C:163 C:422 9.0 0.035 -148.3 160.8 9.0 0.035 0.0 HOH
 2.632
 O
 O
TRP E:163 E:422 10.0 0.039 -145.8 167.6 10.0 0.039 0.0 HOH
 2.793
 O
 O
7co1 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 TRP A:163 A:422 8.0 0.031 -137.3 179.5 8.0 0.031 0.0
TRP C:163 C:422 10.0 0.039 -136.7 178.5 10.0 0.039 0.0
TRP E:163 E:422 6.0 0.024 -137.2 176.5 6.0 0.024 0.0
1u7f 1 P84022 100.0 2e-147 X-RAY
 2004-09-28 TRP A:153 A:380 6.0 0.024 -142.2 176.5 6.0 0.024 0.0 HOH
 3.580
 NE1
 O
TRP C:153 C:380 5.0 0.02 -166.1 171.2 5.0 0.02 0.0 HOH
 2.421
 O
 O
5xoc 1 P84022 100.0 2e-147 X-RAY
 2018-03-28 TRP A:163 A:380 11.0 0.043 -145.1 155.0 3.0 0.012 0.031 B:P0AA25+O75593:0.031
 HOH
 3.160
 NE1
 O
1mjs 1 P84022 100.0 9e-147 X-RAY
 2002-10-16 TRP A:152 A:379 71.0 0.278 -167.9 360.0 71.0 0.278 0.0 HOH
 3.186
 CA
 O
1u7v 1 Q15796 96.97 6e-145 X-RAY
 2004-09-28 TRP A:153 A:422 6.0 0.024 -143.6 177.6 6.0 0.024 0.0
TRP B:153 C:422 4.0 0.016 -164.3 173.1 4.0 0.016 0.0
5xod 1 Q15796 97.46 3e-144 X-RAY
 2018-03-28 TRP A:163 A:422 6.0 0.024 -152.3 162.6 6.0 0.024 0.0 HOH
 4.542
 N
 O
5zoj 1 Q15796 97.46 4e-144 X-RAY
 2018-10-10 TRP A:164 A:422 10.0 0.039 -142.8 147.4 10.0 0.039 0.0
TRP B:164 B:422 12.0 0.047 -143.2 145.6 12.0 0.047 0.0
TRP C:164 C:422 10.0 0.039 -141.1 147.9 10.0 0.039 0.0
1dev 1 Q15796 97.45 9e-144 X-RAY
 2000-01-21 TRP A:162 A:422 3.0 0.012 -158.2 175.8 3.0 0.012 0.0
TRP C:162 C:422 197.0 0.773 -106.9 -28.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p84022-f1 1 P84022 100.0 0.0 TRP A:380 A:380 0.0 0.0 -145.3 170.4
af-q15796-f1 1 Q15796 83.73 0.0 TRP A:422 A:422 0.0 0.0 -142.6 170.6