Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr15 67479834 . G A CCDS10222.1:NM_005902.3:c.1141Gga>Aga_NP_005893.1:p.381G>R Homo sapiens SMAD family member 3 (SMAD3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1khx 1 Q15796 92.51 1e-157 X-RAY
 2002-02-06 GLY A:183 A:423 10.0 0.133 S 95.4 -161.4 10.0 0.133 0.0 HOH
 3.445
 C
 O
6zvq 1 Q15796 92.51 1e-157 X-RAY
 2021-06-09 GLY A:183 A:423 12.0 0.16 S 109.3 -162.6 12.0 0.16 0.0 SO4
GOL
HOH
 5.899
7.246
4.185
 CA
C
CA
 O3
HO1
O
1mk2 1 P84022 100.0 4e-154 X-RAY
 2002-10-16 GLY A:162 A:380 10.0 0.133 S 117.2 -178.8 3.0 0.04 0.093 A:P84022:0.093
 ACY
ACY
 5.284
6.759
 N
O
 O
O
6m64 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 GLY A:164 A:423 13.0 0.173 S 87.2 -179.7 13.0 0.173 0.0 HOH
 3.645
 CA
 O
GLY C:164 C:423 11.0 0.147 S 90.3 -178.9 11.0 0.147 0.0 HOH
 3.526
 C
 O
GLY E:164 E:423 13.0 0.173 S 101.5 -167.0 13.0 0.173 0.0 HOH
 3.076
 O
 O
7co1 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 GLY A:164 A:423 11.0 0.147 S 90.4 -165.2 11.0 0.147 0.0
GLY C:164 C:423 10.0 0.133 S 88.9 -164.9 10.0 0.133 0.0
GLY E:164 E:423 8.0 0.107 S 86.0 -163.7 8.0 0.107 0.0
1u7f 1 P84022 100.0 2e-147 X-RAY
 2004-09-28 GLY A:154 A:381 7.0 0.093 S 86.2 -166.9 7.0 0.093 0.0 HOH
 3.797
 CA
 O
GLY C:154 C:381 10.0 0.133 S 90.2 -158.1 10.0 0.133 0.0 HOH
 3.425
 C
 O
5xoc 1 P84022 100.0 2e-147 X-RAY
 2018-03-28 GLY A:164 A:381 18.0 0.24 S 135.0 -169.0 0.0 0.0 0.24 B:P0AA25+O75593:0.24
 HOH
 6.547
 C
 O
1mjs 1 P84022 100.0 9e-147 X-RAY
 2002-10-16 GLY A:153 NA:NA DO NA DO DO DO NA NA NA
1u7v 1 Q15796 96.97 6e-145 X-RAY
 2004-09-28 GLY A:154 A:423 8.0 0.107 S 84.6 -170.0 8.0 0.107 0.0
GLY B:154 C:423 7.0 0.093 S 87.9 -156.0 7.0 0.093 0.0
5xod 1 Q15796 97.46 3e-144 X-RAY
 2018-03-28 GLY A:164 A:423 11.0 0.147 S 126.2 -149.4 11.0 0.147 0.0 HOH
 6.272
 N
 O
5zoj 1 Q15796 97.46 4e-144 X-RAY
 2018-10-10 GLY A:165 A:423 14.0 0.187 S 146.7 -164.8 13.0 0.173 0.014 D:Q9Y2U8:0.013
GLY B:165 B:423 22.0 0.293 S 145.6 -162.3 22.0 0.293 0.0
GLY C:165 C:423 15.0 0.2 S 148.7 -166.0 15.0 0.2 0.0
1dev 1 Q15796 97.45 9e-144 X-RAY
 2000-01-21 GLY A:163 A:423 8.0 0.107 S 66.0 -163.7 8.0 0.107 0.0
GLY C:163 C:423 81.0 1.0 -172.4 360.0 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p84022-f1 1 P84022 100.0 0.0 GLY A:381 A:381 7.0 0.093 S 95.7 -172.8
af-q15796-f1 1 Q15796 83.73 0.0 GLY A:423 A:423 3.0 0.04 S 99.6 -169.3