Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 21974164 . C A CCDS10601.1:NM_003366.2:c.472Cta>Ata_NP_003357.2:p.158L>I Homo sapiens ubiquinol-cytochrome c reductase core protein II (UQCRC2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5xte 10 P22695 100.0 0.0 EM
 2017-08-30 LEU J:124 K:158 0.0 0.0 H -61.0 -35.8 0.0 0.0 0.0
LEU U:124 W:158 0.0 0.0 H -60.1 -35.0 0.0 0.0 0.0
5xth 67 P22695 100.0 0.0 EM
 2017-09-13 LEU PB:124 AK:158 0.0 0.0 H -61.0 -35.8 0.0 0.0 0.0
LEU AC:124 AW:158 1.0 0.006 H -60.1 -34.9 1.0 0.006 0.0
5xti 67 P22695 100.0 0.0 EM
 2017-09-13 LEU PB:124 AK:158 0.0 0.0 H -61.0 -35.8 0.0 0.0 0.0
LEU AC:124 AW:158 1.0 0.006 H -60.1 -35.0 1.0 0.006 0.0
1sqb 2 P23004 89.4 0.0 X-RAY
 2004-09-07 LEU B:158 B:144 0.0 0.0 H -63.6 -39.8 0.0 0.0 0.0 HOH
 6.445
 N
 O
1sqp 2 P23004 89.4 0.0 X-RAY
 2005-11-01 LEU B:158 B:144 0.0 0.0 H -65.4 -41.1 0.0 0.0 0.0 HOH
 6.870
 O
 O
4d6t 2 P23004 89.4 0.0 X-RAY
 2015-01-14 LEU B:158 B:144 0.0 0.0 H -53.8 -48.9 0.0 0.0 0.0
4d6u 2 P23004 89.4 0.0 X-RAY
 2015-01-14 LEU B:158 B:144 0.0 0.0 H -46.5 -52.3 0.0 0.0 0.0
5okd 2 P23004 89.4 0.0 X-RAY
 2018-02-28 LEU B:158 B:144 0.0 0.0 H -61.8 -41.8 0.0 0.0 0.0 HOH
 5.280
 O
 O
6fo6 3 P23004 89.4 0.0 EM
 2018-02-28 LEU C:158 B:144 0.0 0.0 H -57.8 -46.8 0.0 0.0 0.0
LEU L:158 O:144 0.0 0.0 H -57.8 -46.8 0.0 0.0 0.0
4d6t 10 P23004 89.18 0.0 X-RAY
 2015-01-14 LEU L:158 O:144 0.0 0.0 H -51.7 -51.7 NA NA NA
4d6u 11 P23004 89.18 0.0 X-RAY
 2015-01-14 LEU L:158 O:144 0.0 0.0 H -45.8 -54.0 NA NA NA
6fo0 2 P23004 89.18 0.0 EM
 2018-02-28 LEU B:158 O:144 2.0 0.012 H -61.5 -40.6 2.0 0.012 0.0
LEU L:158 B:144 2.0 0.012 H -61.5 -40.6 2.0 0.012 0.0
6fo2 2 P23004 89.18 0.0 EM
 2018-02-28 LEU B:158 O:144 1.0 0.006 H -60.5 -38.1 1.0 0.006 0.0
LEU L:158 B:144 1.0 0.006 H -60.5 -38.0 1.0 0.006 0.0
5gup 46 ? 88.3 0.0 EM
 2017-03-29 LEU VA:158 v:158 1.0 0.006 H -61.1 -36.9 1.0 0.006 0.0
LEU GB:158 6:158 0.0 0.0 H -66.6 -35.9 0.0 0.0 0.0
1be3 2 P23004 89.29 0.0 X-RAY
 1999-01-13 LEU B:144 B:144 0.0 0.0 H -61.3 -42.6 0.0 0.0 0.0
1bgy 2 P23004 89.29 0.0 X-RAY
 1999-01-06 LEU B:144 B:144 1.0 0.006 H -56.3 -53.6 1.0 0.006 0.0
LEU M:144 N:144 1.0 0.006 H -54.5 -46.1 1.0 0.006 0.0
1l0l 2 P23004 89.29 0.0 X-RAY
 2003-04-08 LEU B:144 B:144 1.0 0.006 H -63.7 -39.9 1.0 0.006 0.0
1l0n 2 P23004 89.29 0.0 X-RAY
 2003-04-08 LEU B:144 B:144 0.0 0.0 H -50.2 -40.7 0.0 0.0 0.0
1ntk 2 P23004 89.29 0.0 X-RAY
 2003-10-07 LEU B:144 B:144 0.0 0.0 H -59.7 -38.9 0.0 0.0 0.0 HOH
 6.529
 N
 O
1ntm 2 P23004 89.29 0.0 X-RAY
 2003-10-07 LEU B:144 B:144 0.0 0.0 H -59.4 -45.1 0.0 0.0 0.0 HOH
 6.445
 N
 O
1ntz 2 P23004 89.29 0.0 X-RAY
 2003-10-07 LEU B:144 B:144 0.0 0.0 H -55.7 -43.5 0.0 0.0 0.0 HOH
 6.894
 CD1
 O
1nu1 2 P23004 89.29 0.0 X-RAY
 2003-10-07 LEU B:144 B:144 0.0 0.0 H -60.3 -37.2 0.0 0.0 0.0
1pp9 2 P23004 89.29 0.0 X-RAY
 2004-07-20 LEU B:144 B:144 0.0 0.0 H -61.2 -37.2 0.0 0.0 0.0 JZR
HOH
 9.379
6.615
 N
N
 C6'
O
LEU L:144 O:144 0.0 0.0 H -60.6 -39.6 0.0 0.0 0.0 HOH
 5.221
 O
 O
1ppj 2 P23004 89.29 0.0 X-RAY
 2004-07-20 LEU B:144 B:144 0.0 0.0 H -63.4 -39.7 0.0 0.0 0.0 JZR
HOH
 9.342
6.096
 N
N
 C6'
O
LEU L:144 O:144 0.0 0.0 H -64.6 -38.9 0.0 0.0 0.0 HOH
 5.899
 N
 O
1sqq 2 P23004 89.29 0.0 X-RAY
 2005-10-25 LEU B:144 B:144 0.0 0.0 H -56.4 -44.2 0.0 0.0 0.0 HOH
 6.432
 N
 O
1sqv 2 P23004 89.29 0.0 X-RAY
 2005-09-06 LEU B:144 B:144 0.0 0.0 H -59.9 -30.6 0.0 0.0 0.0 HOH
 7.417
 N
 O
1sqx 2 P23004 89.29 0.0 X-RAY
 2005-09-06 LEU B:144 B:144 0.0 0.0 H -55.7 -42.6 0.0 0.0 0.0 HOH
 6.387
 N
 O
2a06 2 P23004 89.29 0.0 X-RAY
 2005-06-21 LEU B:144 B:144 0.0 0.0 H -60.1 -40.3 0.0 0.0 0.0 UNL
UNL
JZR
HOH
 9.981
7.897
9.263
6.264
 C
C
N
N
 O1
O1
C6'
O
LEU L:144 O:144 0.0 0.0 H -59.0 -38.9 0.0 0.0 0.0 UNL
UNL
HOH
 8.201
7.800
5.257
 N
O
O
 O1
O1
O
2fyu 2 P23004 89.29 0.0 X-RAY
 2006-08-29 LEU B:144 B:144 0.0 0.0 H -51.3 -43.2 0.0 0.0 0.0 HOH
 7.178
 CD1
 O
2ybb 10 P23004 89.29 0.0 EM
 2011-10-19 LEU J:144 B:144 0.0 0.0 H -61.2 -37.2 0.0 0.0 0.0 HOH
 6.616
 N
 O
LEU IA:144 b:144 0.0 0.0 H -60.7 -39.6 0.0 0.0 0.0 HOH
 5.221
 O
 O
5gpn 2 P23004 89.29 0.0 EM
 2017-04-05 LEU B:144 B:144 27.0 NA H -56.3 -53.6 27.0 NA NA
LEU N:144 N:144 28.0 NA H -54.6 -46.0 28.0 NA NA
5klv 2 P23004 89.29 0.0 X-RAY
 2016-10-12 LEU B:144 B:144 0.0 0.0 H -57.2 -44.4 0.0 0.0 0.0 GOL
HOH
 6.071
6.719
 H
HD22
 O3
O
5luf 2 P23004 89.29 0.0 EM
 2016-11-30 LEU B:144 m:144 1.0 0.006 H -56.4 -53.6 1.0 0.006 0.0
LEU M:144 n:144 1.0 0.006 H -54.5 -46.1 1.0 0.006 0.0
6nhg 2 P23004 89.29 0.0 X-RAY
 2019-06-19 LEU B:144 B:144 0.0 0.0 H -57.8 -40.4 0.0 0.0 0.0 HOH
 6.262
 HB2
 O
7o37 2 Q9DB77 85.42 0.0 EM
 2021-10-13 LEU B:144 B:144 0.0 0.0 H -71.5 -31.0 0.0 0.0 0.0
LEU L:144 M:144 0.0 0.0 H -61.5 -47.8 0.0 0.0 0.0
7o3c 2 Q9DB77 85.42 0.0 EM
 2021-10-13 LEU B:144 B:144 0.0 0.0 H -73.6 -30.7 0.0 0.0 0.0
LEU L:144 M:144 0.0 0.0 H -59.2 -46.3 0.0 0.0 0.0
7o3e 2 Q9DB77 85.42 0.0 EM
 2021-10-13 LEU B:144 B:144 0.0 0.0 H -71.0 -32.0 0.0 0.0 0.0
LEU I:144 M:144 0.0 0.0 H -59.0 -44.5 0.0 0.0 0.0
7o3h 2 Q9DB77 85.42 0.0 EM
 2021-10-13 LEU B:144 B:144 0.0 0.0 H -61.4 -44.6 0.0 0.0 0.0
LEU L:144 M:144 0.0 0.0 H -59.4 -46.8 0.0 0.0 0.0
6q9e 2 W5Q0F9 89.29 0.0 EM
 2019-08-21 LEU B:144 a2:144 1.0 0.006 H -60.9 -45.3 1.0 0.006 0.0
LEU L:144 a4:144 1.0 0.006 H -64.1 -43.4 1.0 0.006 0.0
6qbx 2 W5Q0F9 89.29 0.0 EM
 2019-08-21 LEU B:144 a2:144 1.0 0.006 H -64.7 -43.1 1.0 0.006 0.0
LEU L:144 a4:144 3.0 0.018 H -63.3 -43.4 3.0 0.018 0.0
6qc2 30 W5Q0F9 89.29 0.0 EM
 2019-08-21 LEU DA:144 a2:144 0.0 0.0 H -67.1 -40.5 0.0 0.0 0.0
LEU NA:144 a4:144 2.0 0.012 H -61.8 -41.6 2.0 0.012 0.0
6qc3 2 W5Q0F9 89.29 0.0 EM
 2019-08-21 LEU B:144 a2:144 1.0 0.006 H -64.4 -43.1 1.0 0.006 0.0
LEU L:144 a4:144 1.0 0.006 H -64.3 -43.3 1.0 0.006 0.0
6qc4 2 W5Q0F9 89.29 0.0 EM
 2019-08-21 LEU B:144 a2:144 2.0 0.012 H -64.7 -40.5 2.0 0.012 0.0
LEU L:144 a4:144 3.0 0.018 H -65.3 -42.8 3.0 0.018 0.0
5j4z 52 W5Q0F9 89.34 0.0 EM
 2016-09-21 LEU DB:128 AB:144 46.0 NA H -61.1 -58.0 46.0 NA NA
LEU OB:128 AM:144 45.0 NA H -61.0 -58.1 45.0 NA NA
5j7y 52 W5Q0F9 89.34 0.0 EM
 2016-09-21 LEU DB:128 AB:144 47.0 NA H -61.1 -58.0 47.0 NA NA
LEU OB:128 AM:144 45.0 NA H -61.0 -58.2 45.0 NA NA
5j8k 52 W5Q0F9 89.34 0.0 EM
 2016-09-21 LEU DB:128 AB:144 46.0 NA H -61.2 -58.0 46.0 NA NA
LEU OB:128 AM:144 46.0 NA H -61.1 -58.1 46.0 NA NA
5nmi 2 P23004 89.34 0.0 X-RAY
 2017-06-14 LEU B:128 B:144 1.0 0.006 H -73.7 -19.5 1.0 0.006 0.0
LEU M:128 O:144 0.0 0.0 H -73.8 -19.5 0.0 0.0 0.0
6zfs 2 P23004 89.29 0.0 X-RAY
 2021-06-30 LEU B:125 B:144 0.0 0.0 H -60.6 -42.3 0.0 0.0 0.0 HOH
 7.731
 N
 O
6zft 2 P23004 89.29 0.0 X-RAY
 2021-06-30 LEU B:125 B:144 0.0 0.0 H -58.5 -43.2 0.0 0.0 0.0 HOH
 8.745
 N
 O
6zfu 2 P23004 89.29 0.0 X-RAY
 2021-06-30 LEU B:125 B:144 0.0 0.0 H -62.3 -40.0 0.0 0.0 0.0
6xvf 2 P23004 89.47 0.0 X-RAY
 2020-07-22 LEU B:123 B:144 0.0 0.0 H -62.7 -40.9 0.0 0.0 0.0 HOH
 8.182
 N
 O
2bcc 2 ? 87.91 0.0 X-RAY
 1999-08-02 LEU B:127 B:144 0.0 0.0 H -49.5 -52.4 0.0 0.0 0.0
3bcc 2 P23004 87.91 0.0 X-RAY
 1998-08-19 LEU B:127 B:144 0.0 0.0 H -49.8 -44.3 0.0 0.0 0.0
6haw 2 P23004 88.28 0.0 X-RAY
 2019-01-16 LEU B:123 B:144 0.0 0.0 H -61.7 -41.2 0.0 0.0 0.0 PO4
PO4
HOH
 7.930
6.149
5.826
 N
CB
O
 O4
O1
O
1bcc 2 P23004 87.68 0.0 X-RAY
 1998-08-19 LEU B:127 B:144 0.0 0.0 H -29.6 -52.2 0.0 0.0 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p22695-f1 1 P22695 100.0 0.0 LEU A:158 A:158 1.0 0.006 H -58.4 -41.1