Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 21982936 . G A CCDS10601.1:NM_003366.2:c.761cGt>cAt_NP_003357.2:p.254R>H Homo sapiens ubiquinol-cytochrome c reductase core protein II (UQCRC2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5xte 10 P22695 100.0 0.0 EM
 2017-08-30 ARG J:220 K:254 85.0 0.378 -146.1 147.4 23.0 0.102 0.276 U:P22695:0.276
ARG U:220 W:254 88.0 0.391 -152.8 163.6 23.0 0.102 0.289 J:P22695:0.289
5xth 67 P22695 100.0 0.0 EM
 2017-09-13 ARG PB:220 AK:254 84.0 0.373 -146.1 147.4 22.0 0.098 0.275 AC:P22695:0.276
ARG AC:220 AW:254 88.0 0.391 -152.8 163.6 23.0 0.102 0.289 PB:P22695:0.289
5xti 67 P22695 100.0 0.0 EM
 2017-09-13 ARG PB:220 AK:254 87.0 0.387 -146.1 147.4 23.0 0.102 0.285 AC:P22695:0.284
ARG AC:220 AW:254 87.0 0.387 -152.8 163.7 22.0 0.098 0.289 PB:P22695:0.289
1sqb 2 P23004 89.4 0.0 X-RAY
 2004-09-07 HIS B:254 B:240 68.0 0.349 -130.3 -52.8 10.0 0.051 0.298 B:P23004:0.297
 HOH
 3.367
 NE2
 O
1sqp 2 P23004 89.4 0.0 X-RAY
 2005-11-01 HIS B:254 B:240 64.0 0.328 -128.9 -59.2 10.0 0.051 0.277 B:P23004:0.277
 HOH
 6.255
 N
 O
4d6t 2 P23004 89.4 0.0 X-RAY
 2015-01-14 HIS B:254 B:240 115.0 0.59 -97.1 -68.6 115.0 0.59 0.0
4d6u 2 P23004 89.4 0.0 X-RAY
 2015-01-14 HIS B:254 B:240 100.0 0.513 -103.6 -71.9 100.0 0.513 0.0
5okd 2 P23004 89.4 0.0 X-RAY
 2018-02-28 HIS B:254 B:240 70.0 0.359 -120.7 -61.9 70.0 0.359 0.0 HOH
 3.335
 CE1
 O
6fo6 3 P23004 89.4 0.0 EM
 2018-02-28 HIS C:254 B:240 94.0 0.482 -129.3 -35.6 30.0 0.154 0.328 L:P23004:0.328
HIS L:254 O:240 95.0 0.487 -129.4 -35.6 32.0 0.164 0.323 C:P23004:0.323
4d6t 10 P23004 89.18 0.0 X-RAY
 2015-01-14 HIS L:254 O:240 118.0 0.605 -97.8 -65.9 NA NA NA
4d6u 11 P23004 89.18 0.0 X-RAY
 2015-01-14 HIS L:254 O:240 75.0 0.385 -104.6 -69.9 NA NA NA
6fo0 2 P23004 89.18 0.0 EM
 2018-02-28 HIS B:254 O:240 94.0 0.482 -119.6 -57.8 45.0 0.231 0.251 L:P23004:0.251
HIS L:254 B:240 95.0 0.487 -119.5 -57.6 48.0 0.246 0.241 B:P23004:0.241
6fo2 2 P23004 89.18 0.0 EM
 2018-02-28 HIS B:254 O:240 108.0 0.554 -124.1 -41.6 50.0 0.256 0.298 L:P23004:0.297
HIS L:254 B:240 109.0 0.559 -124.1 -41.6 51.0 0.262 0.297 B:P23004:0.297
5gup 46 ? 88.3 0.0 EM
 2017-03-29 ARG VA:254 v:254 91.0 0.404 -140.8 154.1 16.0 0.071 0.333 GB:None:0.333
ARG GB:254 6:254 64.0 0.284 -138.0 145.4 6.0 0.027 0.257 VA:None:0.258
1be3 2 P23004 89.29 0.0 X-RAY
 1999-01-13 HIS B:240 B:240 63.0 0.323 -134.2 124.7 63.0 0.323 0.0
1bgy 2 P23004 89.29 0.0 X-RAY
 1999-01-06 HIS B:240 B:240 64.0 0.328 -150.0 119.7 7.0 0.036 0.292 M:P23004:0.292
HIS M:240 N:240 63.0 0.323 -142.1 121.0 7.0 0.036 0.287 B:P23004:0.287
1l0l 2 P23004 89.29 0.0 X-RAY
 2003-04-08 HIS B:240 B:240 61.0 0.313 -133.5 -53.0 61.0 0.313 0.0
1l0n 2 P23004 89.29 0.0 X-RAY
 2003-04-08 HIS B:240 B:240 65.0 0.333 -129.1 -46.6 65.0 0.333 0.0
1ntk 2 P23004 89.29 0.0 X-RAY
 2003-10-07 HIS B:240 B:240 65.0 0.333 -115.0 -63.9 9.0 0.046 0.287 B:P23004:0.287
 HOH
 2.953
 ND1
 O
1ntm 2 P23004 89.29 0.0 X-RAY
 2003-10-07 HIS B:240 B:240 75.0 0.385 -127.1 -64.4 18.0 0.092 0.293 B:P23004:0.292
 HOH
 3.185
 CE1
 O
1ntz 2 P23004 89.29 0.0 X-RAY
 2003-10-07 HIS B:240 B:240 68.0 0.349 -126.7 -56.5 12.0 0.062 0.287 B:P23004:0.287
 HOH
 7.051
 O
 O
1nu1 2 P23004 89.29 0.0 X-RAY
 2003-10-07 HIS B:240 B:240 68.0 0.349 -147.9 -59.0 12.0 0.062 0.287 B:P23004:0.287
1pp9 2 P23004 89.29 0.0 X-RAY
 2004-07-20 HIS B:240 B:240 62.0 0.318 -119.5 -52.1 8.0 0.041 0.277 L:P23004:0.277
 HOH
 2.564
 NE2
 O
HIS L:240 O:240 61.0 0.313 -122.8 -48.9 8.0 0.041 0.272 B:P23004:0.272
 HOH
 2.567
 NE2
 O
1ppj 2 P23004 89.29 0.0 X-RAY
 2004-07-20 HIS B:240 B:240 65.0 0.333 -124.0 -55.8 8.0 0.041 0.292 L:P23004:0.292
 HOH
 2.689
 NE2
 O
HIS L:240 O:240 65.0 0.333 -125.8 -51.4 7.0 0.036 0.297 B:P23004:0.297
 HOH
 2.579
 NE2
 O
1sqq 2 P23004 89.29 0.0 X-RAY
 2005-10-25 HIS B:240 B:240 69.0 0.354 -141.9 -62.7 12.0 0.062 0.292 B:P23004:0.292
 HOH
 6.480
 CD2
 O
1sqv 2 P23004 89.29 0.0 X-RAY
 2005-09-06 HIS B:240 B:240 73.0 0.374 -145.1 -42.3 13.0 0.067 0.307 B:P23004:0.308
 HOH
 5.026
 NE2
 O
1sqx 2 P23004 89.29 0.0 X-RAY
 2005-09-06 HIS B:240 B:240 74.0 0.379 -116.5 -55.7 12.0 0.062 0.317 B:P23004:0.318
 HOH
 2.780
 ND1
 O
2a06 2 P23004 89.29 0.0 X-RAY
 2005-06-21 HIS B:240 B:240 66.0 0.338 -126.5 -52.9 8.0 0.041 0.297 L:P23004:0.297
 UNL
HOH
 5.323
2.747
 CE1
NE2
 O1
O
HIS L:240 O:240 66.0 0.338 -133.0 -47.4 8.0 0.041 0.297 B:P23004:0.297
 UNL
UNL
HOH
 8.892
9.367
2.591
 ND1
CE1
NE2
 O1
O1
O
2fyu 2 P23004 89.29 0.0 X-RAY
 2006-08-29 HIS B:240 B:240 76.0 0.39 -135.1 -47.9 14.0 0.072 0.318 B:P23004:0.318
 HOH
 6.145
 N
 O
2ybb 10 P23004 89.29 0.0 EM
 2011-10-19 HIS J:240 B:240 62.0 0.318 -119.4 -52.2 8.0 0.041 0.277 IA:P23004:0.277
 HOH
 2.563
 NE2
 O
HIS IA:240 b:240 63.0 0.323 -122.8 -48.9 9.0 0.046 0.277 J:P23004:0.277
 HOH
 2.567
 NE2
 O
5gpn 2 P23004 89.29 0.0 EM
 2017-04-05 HIS B:240 B:240 44.0 NA -150.0 119.8 39.0 NA NA N:P23004:NA
HIS N:240 N:240 43.0 NA -142.1 120.9 39.0 NA NA B:P23004:NA
5klv 2 P23004 89.29 0.0 X-RAY
 2016-10-12 HIS B:240 B:240 78.0 0.4 -140.3 -43.8 16.0 0.082 0.318 B:P23004:0.318
 GOL
HOH
 6.315
4.326
 ND1
O
 H12
O
5luf 2 P23004 89.29 0.0 EM
 2016-11-30 HIS B:240 m:240 64.0 0.328 -150.0 119.7 7.0 0.036 0.292 M:P23004:0.292
HIS M:240 n:240 64.0 0.328 -142.1 120.9 6.0 0.031 0.297 B:P23004:0.297
6nhg 2 P23004 89.29 0.0 X-RAY
 2019-06-19 HIS B:240 B:240 64.0 0.328 -129.7 -38.3 9.0 0.046 0.282 B:P23004:0.282
 HOH
 2.795
 NE2
 O
7o37 2 Q9DB77 85.42 0.0 EM
 2021-10-13 ARG B:240 B:240 115.0 0.511 -122.9 -33.0 27.0 0.12 0.391 L:Q9DB77:0.391
ARG L:240 M:240 113.0 0.502 -118.3 -54.0 16.0 0.071 0.431 B:Q9DB77:0.431
7o3c 2 Q9DB77 85.42 0.0 EM
 2021-10-13 ARG B:240 B:240 108.0 0.48 -119.0 -43.2 23.0 0.102 0.378 L:Q9DB77:0.378
ARG L:240 M:240 116.0 0.516 -114.7 -58.6 17.0 0.076 0.44 B:Q9DB77:0.44
7o3e 2 Q9DB77 85.42 0.0 EM
 2021-10-13 ARG B:240 B:240 120.0 0.533 -130.2 -31.0 28.0 0.124 0.409 I:Q9DB77:0.409
ARG I:240 M:240 108.0 0.48 -115.4 -57.6 24.0 0.107 0.373 B:Q9DB77:0.373
7o3h 2 Q9DB77 85.42 0.0 EM
 2021-10-13 ARG B:240 B:240 109.0 0.484 -127.9 -32.2 29.0 0.129 0.355 L:Q9DB77:0.356
ARG L:240 M:240 101.0 0.449 -121.3 -47.5 20.0 0.089 0.36 B:Q9DB77:0.36
6q9e 2 W5Q0F9 89.29 0.0 EM
 2019-08-21 ARG B:240 a2:240 90.0 0.4 -114.7 -58.4 13.0 0.058 0.342 L:W5Q0F9:0.342
ARG L:240 a4:240 96.0 0.427 -107.7 -46.8 27.0 0.12 0.307 B:W5Q0F9:0.307
6qbx 2 W5Q0F9 89.29 0.0 EM
 2019-08-21 ARG B:240 a2:240 79.0 0.351 -111.9 -59.1 11.0 0.049 0.302 L:W5Q0F9:0.302
ARG L:240 a4:240 98.0 0.436 -106.3 -54.3 20.0 0.089 0.347 B:W5Q0F9:0.347
6qc2 30 W5Q0F9 89.29 0.0 EM
 2019-08-21 ARG DA:240 a2:240 108.0 0.48 -116.3 -56.5 20.0 0.089 0.391 NA:W5Q0F9:0.391
ARG NA:240 a4:240 110.0 0.489 -76.9 -34.2 38.0 0.169 0.32 DA:W5Q0F9:0.32
6qc3 2 W5Q0F9 89.29 0.0 EM
 2019-08-21 ARG B:240 a2:240 100.0 0.444 -75.1 -63.2 16.0 0.071 0.373 L:W5Q0F9:0.373
ARG L:240 a4:240 60.0 0.267 -111.0 -60.9 21.0 0.093 0.174 B:W5Q0F9:0.173
6qc4 2 W5Q0F9 89.29 0.0 EM
 2019-08-21 ARG B:240 a2:240 106.0 0.471 -113.2 -57.5 16.0 0.071 0.4 L:W5Q0F9:0.4
ARG L:240 a4:240 74.0 0.329 -78.3 -62.1 14.0 0.062 0.267 B:W5Q0F9:0.267
5j4z 52 W5Q0F9 89.34 0.0 EM
 2016-09-21 ARG DB:224 AB:240 82.0 NA -89.0 -14.3 82.0 NA NA
ARG OB:224 AM:240 83.0 NA -89.0 -14.2 83.0 NA NA
5j7y 52 W5Q0F9 89.34 0.0 EM
 2016-09-21 ARG DB:224 AB:240 84.0 NA -89.0 -14.3 84.0 NA NA
ARG OB:224 AM:240 82.0 NA -89.0 -14.3 82.0 NA NA
5j8k 52 W5Q0F9 89.34 0.0 EM
 2016-09-21 ARG DB:224 AB:240 83.0 NA -89.1 -14.3 83.0 NA NA
ARG OB:224 AM:240 83.0 NA -89.0 -14.3 82.0 NA NA DB:W5Q0F9:NA
5nmi 2 P23004 89.34 0.0 X-RAY
 2017-06-14 HIS B:224 B:240 72.0 0.369 -143.3 -178.5 6.0 0.031 0.338 M:P23004:0.338
HIS M:224 O:240 72.0 0.369 -143.2 -178.5 6.0 0.031 0.338 B:P23004:0.338
6zfs 2 P23004 89.29 0.0 X-RAY
 2021-06-30 HIS B:221 B:240 72.0 0.369 -116.9 -59.0 72.0 0.369 0.0
6zft 2 P23004 89.29 0.0 X-RAY
 2021-06-30 HIS B:221 B:240 75.0 0.385 -122.1 -54.7 75.0 0.385 0.0
6zfu 2 P23004 89.29 0.0 X-RAY
 2021-06-30 HIS B:221 B:240 71.0 0.364 -118.7 -59.2 71.0 0.364 0.0
6xvf 2 P23004 89.47 0.0 X-RAY
 2020-07-22 HIS B:219 B:240 70.0 0.359 -119.1 -58.3 14.0 0.072 0.287 B:P23004:0.287
2bcc 2 ? 87.91 0.0 X-RAY
 1999-08-02 ARG B:223 B:240 120.0 0.533 -161.5 149.5 120.0 0.533 0.0
3bcc 2 P23004 87.91 0.0 X-RAY
 1998-08-19 ARG B:223 B:240 116.0 0.516 -154.8 143.1 24.0 0.107 0.409 B:P23004:0.409
6haw 2 P23004 88.28 0.0 X-RAY
 2019-01-16 HIS B:214 B:240 94.0 0.482 -121.5 -58.0 94.0 0.482 0.0
1bcc 2 P23004 87.68 0.0 X-RAY
 1998-08-19 ARG B:223 B:240 111.0 0.493 -150.5 149.3 23.0 0.102 0.391 B:P23004:0.391

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p22695-f1 1 P22695 100.0 0.0 ARG A:254 A:254 136.0 0.604 -124.0 -24.7