Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 21983253 . G A CCDS10601.1:NM_003366.2:c.776cGa>cAa_NP_003357.2:p.259R>Q Homo sapiens ubiquinol-cytochrome c reductase core protein II (UQCRC2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5xte 10 P22695 100.0 0.0 EM
 2017-08-30 ARG J:225 K:259 64.0 0.284 E -78.5 151.6 54.0 0.24 0.044 U:P22695:0.044
ARG U:225 W:259 72.0 0.32 E -132.7 154.9 71.0 0.316 0.004 J:P22695:0.004
5xth 67 P22695 100.0 0.0 EM
 2017-09-13 ARG PB:225 AK:259 63.0 0.28 E -78.5 151.6 53.0 0.236 0.044 AC:P22695:0.044
ARG AC:225 AW:259 72.0 0.32 E -132.7 154.9 71.0 0.316 0.004 PB:P22695:0.004
5xti 67 P22695 100.0 0.0 EM
 2017-09-13 ARG PB:225 AK:259 62.0 0.276 E -78.5 151.7 53.0 0.236 0.04 AC:P22695:0.04
ARG AC:225 AW:259 71.0 0.316 E -132.7 154.9 70.0 0.311 0.005 PB:P22695:0.004
1sqb 2 P23004 89.4 0.0 X-RAY
 2004-09-07 ARG B:259 B:245 77.0 0.342 E -123.1 130.5 76.0 0.338 0.004 B:P23004:0.004
 HOH
 2.714
 N
 O
1sqp 2 P23004 89.4 0.0 X-RAY
 2005-11-01 ARG B:259 B:245 76.0 0.338 E -125.1 127.6 76.0 0.338 0.0 HOH
 2.677
 O
 O
4d6t 2 P23004 89.4 0.0 X-RAY
 2015-01-14 ARG B:259 B:245 69.0 0.307 E -131.1 100.0 69.0 0.307 0.0
4d6u 2 P23004 89.4 0.0 X-RAY
 2015-01-14 ARG B:259 B:245 69.0 0.307 E -131.3 109.2 69.0 0.307 0.0
5okd 2 P23004 89.4 0.0 X-RAY
 2018-02-28 ARG B:259 B:245 66.0 0.293 E -132.2 102.2 66.0 0.293 0.0 HOH
 9.117
 N
 O
6fo6 3 P23004 89.4 0.0 EM
 2018-02-28 ARG C:259 B:245 77.0 0.342 E -144.8 97.6 74.0 0.329 0.013 L:P23004:0.013
ARG L:259 O:245 78.0 0.347 E -144.8 97.6 75.0 0.333 0.014 C:P23004:0.013
4d6t 10 P23004 89.18 0.0 X-RAY
 2015-01-14 ARG L:259 O:245 68.0 0.302 E -133.0 98.4 NA NA NA
4d6u 11 P23004 89.18 0.0 X-RAY
 2015-01-14 ARG L:259 O:245 69.0 0.307 E -131.9 109.3 NA NA NA
6fo0 2 P23004 89.18 0.0 EM
 2018-02-28 ARG B:259 O:245 85.0 0.378 E -130.7 143.3 82.0 0.364 0.014 L:P23004:0.013
ARG L:259 B:245 84.0 0.373 E -130.7 143.2 81.0 0.36 0.013 B:P23004:0.013
6fo2 2 P23004 89.18 0.0 EM
 2018-02-28 ARG B:259 O:245 78.0 0.347 E -141.2 144.4 77.0 0.342 0.005 L:P23004:0.004
ARG L:259 B:245 76.0 0.338 E -141.2 144.4 76.0 0.338 0.0
5gup 46 ? 88.3 0.0 EM
 2017-03-29 ARG VA:259 v:259 58.0 0.258 -138.7 96.1 58.0 0.258 0.0
ARG GB:259 6:259 89.0 0.396 E -132.8 97.6 80.0 0.356 0.04 VA:None:0.04
1be3 2 P23004 89.29 0.0 X-RAY
 1999-01-13 ARG B:245 B:245 81.0 0.36 E -121.9 119.7 81.0 0.36 0.0
1bgy 2 P23004 89.29 0.0 X-RAY
 1999-01-06 ARG B:245 B:245 79.0 0.351 E -119.8 123.2 77.0 0.342 0.009 M:P23004:0.009
ARG M:245 N:245 76.0 0.338 E -117.9 124.2 73.0 0.324 0.014 B:P23004:0.013
1l0l 2 P23004 89.29 0.0 X-RAY
 2003-04-08 ARG B:245 B:245 80.0 0.356 E -121.9 118.9 80.0 0.356 0.0
1l0n 2 P23004 89.29 0.0 X-RAY
 2003-04-08 ARG B:245 B:245 70.0 0.311 E -128.3 123.4 70.0 0.311 0.0
1ntk 2 P23004 89.29 0.0 X-RAY
 2003-10-07 ARG B:245 B:245 73.0 0.324 E -123.5 131.3 73.0 0.324 0.0 HOH
 2.933
 NH1
 O
1ntm 2 P23004 89.29 0.0 X-RAY
 2003-10-07 ARG B:245 B:245 75.0 0.333 E -125.4 131.1 75.0 0.333 0.0 HOH
 2.867
 NH1
 O
1ntz 2 P23004 89.29 0.0 X-RAY
 2003-10-07 ARG B:245 B:245 70.0 0.311 E -121.1 122.6 70.0 0.311 0.0 HOH
 9.106
 O
 O
1nu1 2 P23004 89.29 0.0 X-RAY
 2003-10-07 ARG B:245 B:245 77.0 0.342 E -126.3 127.4 77.0 0.342 0.0
1pp9 2 P23004 89.29 0.0 X-RAY
 2004-07-20 ARG B:245 B:245 74.0 0.329 E -117.0 127.4 74.0 0.329 0.0 HOH
 2.688
 NH1
 O
ARG L:245 O:245 74.0 0.329 E -116.9 125.9 74.0 0.329 0.0 HOH
 2.734
 NH1
 O
1ppj 2 P23004 89.29 0.0 X-RAY
 2004-07-20 ARG B:245 B:245 74.0 0.329 E -115.2 121.7 74.0 0.329 0.0 HOH
 2.799
 NH1
 O
ARG L:245 O:245 72.0 0.32 E -114.0 123.2 71.0 0.316 0.004 B:P23004:0.004
 HOH
 2.685
 NH2
 O
1sqq 2 P23004 89.29 0.0 X-RAY
 2005-10-25 ARG B:245 B:245 79.0 0.351 E -142.5 114.6 77.0 0.342 0.009 B:P23004:0.009
 HOH
 2.984
 NH1
 O
1sqv 2 P23004 89.29 0.0 X-RAY
 2005-09-06 ARG B:245 B:245 80.0 0.356 E -122.8 137.7 78.0 0.347 0.009 B:P23004:0.009
 HOH
 2.735
 NH1
 O
1sqx 2 P23004 89.29 0.0 X-RAY
 2005-09-06 ARG B:245 B:245 76.0 0.338 E -124.7 127.1 76.0 0.338 0.0 HOH
 3.177
 NE
 O
2a06 2 P23004 89.29 0.0 X-RAY
 2005-06-21 ARG B:245 B:245 71.0 0.316 E -112.8 121.6 71.0 0.316 0.0 UNL
UNL
HOH
 4.093
7.725
2.554
 NH2
N
NH2
 O1
O1
O
ARG L:245 O:245 70.0 0.311 E -110.4 120.8 69.0 0.307 0.004 B:P23004:0.004
 UNL
HOH
 6.036
2.844
 CD
NH1
 O1
O
2fyu 2 P23004 89.29 0.0 X-RAY
 2006-08-29 ARG B:245 B:245 69.0 0.307 E -129.4 113.3 69.0 0.307 0.0 HOH
 9.223
 O
 O
2ybb 10 P23004 89.29 0.0 EM
 2011-10-19 ARG J:245 B:245 75.0 0.333 E -116.9 127.4 75.0 0.333 0.0 HOH
 2.687
 NH1
 O
ARG IA:245 b:245 76.0 0.338 E -116.8 125.9 76.0 0.338 0.0 HOH
 2.734
 NH1
 O
5gpn 2 P23004 89.29 0.0 EM
 2017-04-05 ARG B:245 B:245 86.0 NA E -119.8 123.2 86.0 NA NA
ARG N:245 N:245 89.0 NA E -117.9 124.2 89.0 NA NA
5klv 2 P23004 89.29 0.0 X-RAY
 2016-10-12 ARG B:245 B:245 72.0 0.32 E -126.2 117.6 72.0 0.32 0.0 GOL
HOH
 2.047
2.351
 HE
H
 HO2
O
5luf 2 P23004 89.29 0.0 EM
 2016-11-30 ARG B:245 m:245 80.0 0.356 E -119.8 123.2 77.0 0.342 0.014 M:P23004:0.013
ARG M:245 n:245 75.0 0.333 E -117.9 124.3 72.0 0.32 0.013 B:P23004:0.013
6nhg 2 P23004 89.29 0.0 X-RAY
 2019-06-19 ARG B:245 B:245 72.0 0.32 E -121.4 131.3 72.0 0.32 0.0 HOH
 6.804
 HD2
 O
7o37 2 Q9DB77 85.42 0.0 EM
 2021-10-13 ARG B:245 B:245 67.0 0.298 E -124.4 131.0 42.0 0.187 0.111 L:Q9DB77:0.111
ARG L:245 M:245 57.0 0.253 E -131.6 125.4 43.0 0.191 0.062 B:Q9DB77:0.062
7o3c 2 Q9DB77 85.42 0.0 EM
 2021-10-13 ARG B:245 B:245 62.0 0.276 E -136.8 92.3 42.0 0.187 0.089 L:Q9DB77:0.089
ARG L:245 M:245 68.0 0.302 E -127.8 115.3 48.0 0.213 0.089 B:Q9DB77:0.089
7o3e 2 Q9DB77 85.42 0.0 EM
 2021-10-13 ARG B:245 B:245 77.0 0.342 E -127.0 127.3 46.0 0.204 0.138 I:Q9DB77:0.138
ARG I:245 M:245 72.0 0.32 E -121.5 124.9 46.0 0.204 0.116 B:Q9DB77:0.116
7o3h 2 Q9DB77 85.42 0.0 EM
 2021-10-13 ARG B:245 B:245 63.0 0.28 E -127.1 130.4 44.0 0.196 0.084 L:Q9DB77:0.084
ARG L:245 M:245 63.0 0.28 E -114.2 120.9 41.0 0.182 0.098 B:Q9DB77:0.098
6q9e 2 W5Q0F9 89.29 0.0 EM
 2019-08-21 ARG B:245 a2:245 65.0 0.289 E -113.6 150.8 60.0 0.267 0.022 L:W5Q0F9:0.022
ARG L:245 a4:245 104.0 0.462 E -109.8 132.5 74.0 0.329 0.133 B:W5Q0F9:0.133
6qbx 2 W5Q0F9 89.29 0.0 EM
 2019-08-21 ARG B:245 a2:245 80.0 0.356 E -117.2 141.8 61.0 0.271 0.085 L:W5Q0F9:0.084
ARG L:245 a4:245 115.0 0.511 E -111.8 131.5 86.0 0.382 0.129 B:W5Q0F9:0.129
6qc2 30 W5Q0F9 89.29 0.0 EM
 2019-08-21 ARG DA:245 a2:245 68.0 0.302 E -110.4 128.9 58.0 0.258 0.044 NA:W5Q0F9:0.044
ARG NA:245 a4:245 115.0 0.511 E -111.7 123.1 69.0 0.307 0.204 DA:W5Q0F9:0.204
6qc3 2 W5Q0F9 89.29 0.0 EM
 2019-08-21 ARG B:245 a2:245 73.0 0.324 E -103.7 150.5 73.0 0.324 0.0
ARG L:245 a4:245 121.0 0.538 E -104.0 130.6 72.0 0.32 0.218 B:W5Q0F9:0.218
6qc4 2 W5Q0F9 89.29 0.0 EM
 2019-08-21 ARG B:245 a2:245 67.0 0.298 E -112.4 118.8 66.0 0.293 0.005 L:W5Q0F9:0.004
ARG L:245 a4:245 120.0 0.533 E -116.2 125.1 74.0 0.329 0.204 B:W5Q0F9:0.204
5j4z 52 W5Q0F9 89.34 0.0 EM
 2016-09-21 ARG DB:229 AB:245 81.0 NA -102.1 126.6 81.0 NA NA
ARG OB:229 AM:245 81.0 NA -102.2 126.6 81.0 NA NA
5j7y 52 W5Q0F9 89.34 0.0 EM
 2016-09-21 ARG DB:229 AB:245 82.0 NA -102.1 126.6 82.0 NA NA
ARG OB:229 AM:245 82.0 NA -102.2 126.6 82.0 NA NA
5j8k 52 W5Q0F9 89.34 0.0 EM
 2016-09-21 ARG DB:229 AB:245 82.0 NA -102.1 126.7 82.0 NA NA
ARG OB:229 AM:245 82.0 NA -102.2 126.5 82.0 NA NA
5nmi 2 P23004 89.34 0.0 X-RAY
 2017-06-14 ARG B:229 B:245 62.0 0.276 E -125.5 98.8 62.0 0.276 0.0
ARG M:229 O:245 61.0 0.271 E -125.4 98.4 61.0 0.271 0.0
6zfs 2 P23004 89.29 0.0 X-RAY
 2021-06-30 ARG B:226 B:245 70.0 0.311 E -125.6 105.7 70.0 0.311 0.0 HOH
 4.693
 NH2
 O
6zft 2 P23004 89.29 0.0 X-RAY
 2021-06-30 ARG B:226 B:245 71.0 0.316 E -132.2 102.9 71.0 0.316 0.0
6zfu 2 P23004 89.29 0.0 X-RAY
 2021-06-30 ARG B:226 B:245 69.0 0.307 E -129.4 102.4 69.0 0.307 0.0
6xvf 2 P23004 89.47 0.0 X-RAY
 2020-07-22 ARG B:224 B:245 69.0 0.307 E -126.6 106.7 69.0 0.307 0.0
2bcc 2 ? 87.91 0.0 X-RAY
 1999-08-02 ARG B:228 B:245 76.0 0.338 E -113.5 130.3 76.0 0.338 0.0
3bcc 2 P23004 87.91 0.0 X-RAY
 1998-08-19 ARG B:228 B:245 77.0 0.342 E -92.5 141.4 72.0 0.32 0.022 B:P23004:0.022
6haw 2 P23004 88.28 0.0 X-RAY
 2019-01-16 ARG B:219 B:245 71.0 0.316 E -125.0 102.1 71.0 0.316 0.0
1bcc 2 P23004 87.68 0.0 X-RAY
 1998-08-19 ARG B:228 B:245 76.0 0.338 E -112.1 130.7 69.0 0.307 0.031 B:P23004:0.031

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p22695-f1 1 P22695 100.0 0.0 ARG A:259 A:259 71.0 0.316 E -122.3 126.6