Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 31004521 . G A CCDS10699.1:NM_052874.3:c.716tCt>tTt_NP_443106.1:p.239S>F Homo sapiens syntaxin 1B (STX1B), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3c98 2 P32851 83.15 8e-149 X-RAY
 2008-03-25 ALA B:252 B:240 41.0 0.357 -91.7 131.9 16.0 0.139 0.218 A:P61765:0.217
 HOH
 4.871
 CB
 O
4jeh 2 P32851 85.6 6e-145 X-RAY
 2013-07-17 ALA B:217 B:240 42.0 0.365 -75.3 135.2 10.0 0.087 0.278 A:P61765:0.278
 HOH
 9.182
 CB
 O
6mdm 3 P32851 82.03 3e-139 EM
 2018-09-19 ALA H:240 I:240 42.0 0.365 H -60.5 -43.3 16.0 0.139 0.226 G:P60881:0.096
I:P63045:0.139
6mdn 3 P32851 82.03 3e-139 EM
 2018-09-19 ALA H:240 I:240 36.0 0.313 H -59.1 -43.8 4.0 0.035 0.278 I:P63045:0.209
G:P60881:0.07
6ip1 2 P32851 82.14 3e-137 EM
 2019-04-24 ALA B:241 B:240 53.0 0.461 H -70.9 -15.2 1.0 0.009 0.452 C:P60881:0.096
A:P63045:0.4
4jeu 2 P32851 81.4 4e-130 X-RAY
 2013-07-17 ALA B:239 B:240 39.0 0.339 -159.5 116.9 21.0 0.183 0.156 A:P61765:0.157
2m8r 1 P32851 85.85 2e-63 NMR
 2013-11-20 ALA A:61 A:240 42.0 0.365 H -47.1 -59.7 42.0 0.365 0.0
3hd7 2 P32851 85.85 2e-63 X-RAY
 2009-07-14 ALA B:61 B:240 49.0 0.426 H -51.9 -36.5 1.0 0.009 0.417 C:P60881:0.104
A:P63045:0.365
ALA F:61 F:240 50.0 0.435 H -40.6 -37.6 NA NA NA
3ipd 2 P32851 85.85 2e-63 X-RAY
 2009-09-01 ALA B:61 B:240 52.0 0.452 H -65.9 -26.6 6.0 0.052 0.4 A:P63045:0.33
C:P60881:0.07
ALA F:61 F:240 52.0 0.452 H -64.6 -26.6 NA NA NA
1sfc 2 P32851 89.02 6e-46 X-RAY
 1998-10-28 ALA B:61 B:240 46.0 0.4 H -50.5 -39.8 0.0 0.0 0.4 D:P60881:0.043
C:P60881:0.104
A:P63045:0.365
 SR
HOH
 9.974
8.718
 CA
N
 SR
O
ALA F:61 F:240 46.0 0.4 H -65.4 -39.4 NA NA NA
ALA J:61 J:240 48.0 0.417 H -51.8 -58.8 NA NA NA
1jth 2 P32851 93.51 3e-45 X-RAY
 2001-11-28 ALA B:50 B:240 45.0 0.391 H -66.6 -40.4 0.0 0.0 0.391 C:P60881:0.113
A:P60881:0.339
 HOH
 7.434
 O
 O
ALA D:50 D:240 43.0 0.374 H -104.6 -26.6 0.0 0.0 0.374 C:P60881:0.304
A:P60881:0.148
1hvv 1 P32851 93.33 7e-44 X-RAY
 2001-01-31 ALA A:51 A:240 47.0 0.409 H -70.4 -40.6 0.0 0.0 0.409 C:P32851:0.113
B:P32851:0.365
 HOH
 3.891
 CA
 O
ALA B:51 B:240 50.0 0.435 H -66.3 -37.4 23.0 0.2 0.235 C:P32851:0.191
D:P32851:0.104
 HOH
 3.777
 CB
 O
ALA C:51 C:240 54.0 0.47 H -61.6 -43.6 0.0 0.0 0.47 D:P32851:0.426
A:P32851:0.148
 HOH
 4.254
 N
 O
ALA D:51 D:240 50.0 0.435 H -65.9 -38.6 15.0 0.13 0.305 A:P32851:0.157
B:P32851:0.191
 HOH
 3.967
 N
 O
2n1t 2 P32851 91.67 4e-41 NMR
 2015-06-03 ALA B:53 B:240 50.0 0.435 H -60.2 -38.7 0.0 0.0 0.435 A:P63045:0.4
C:P60880:0.061
1urq 2 P32851 91.67 5e-41 X-RAY
 2004-08-26 ALA B:56 B:240 50.0 0.435 H -65.8 -44.8 0.0 0.0 0.435 D:P13795:0.017
C:P13795:0.113
A:Q9Z152:0.4
 HOH
 4.940
 O
 O
5kj7 2 P32851 92.42 1e-36 X-RAY
 2016-10-19 ALA B:50 B:240 48.0 0.417 H -65.2 -34.9 1.0 0.009 0.408 D:P60881:0.017
A:P63025:0.339
C:P60881:0.104
 HOH
 9.396
 N
 O
ALA H:50 H:240 49.0 0.426 H -65.4 -35.6 NA NA NA
5kj8 2 P32851 92.42 1e-36 X-RAY
 2016-10-19 ALA B:50 B:240 47.0 0.409 H -62.8 -39.9 1.0 0.009 0.4 D:P60881:0.009
A:P63025:0.339
C:P60881:0.104
ALA H:50 H:240 48.0 0.417 H -63.1 -40.0 NA NA NA
6wvw 2 P32851 92.42 1e-36 X-RAY
 2021-03-17 ALA B:50 B:240 48.0 0.417 H -65.8 -40.5 1.0 0.009 0.408 D:P60881:0.035
C:P60881:0.113
A:P63045:0.339
 HOH
 4.616
 O
 O
ALA F:50 F:240 49.0 0.426 H -65.6 -41.7 NA NA NA
3j96 4 P32851 92.42 1e-36 EM
 2015-01-28 ALA L:51 L:240 48.0 0.417 H -58.6 -32.9 3.0 0.026 0.391 M:None:0.104
K:P63045:0.348
3j97 4 P32851 92.42 1e-36 EM
 2015-01-28 ALA L:51 L:240 41.0 0.357 H -56.0 -28.8 4.0 0.035 0.322 M:None:0.052
K:P63045:0.27
3j98 4 P32851 92.42 1e-36 EM
 2015-01-28 ALA L:51 L:240 40.0 0.348 H -59.9 -27.2 3.0 0.026 0.322 M:None:0.13
K:P63045:0.191
3j99 4 P32851 92.42 1e-36 EM
 2015-01-28 ALA L:51 L:240 39.0 0.339 H -59.9 -27.3 3.0 0.026 0.313 M:None:0.13
K:P63045:0.191
5ccg 2 P32851 92.42 1e-36 X-RAY
 2015-08-12 ALA B:51 B:240 47.0 0.409 H -62.4 -39.6 1.0 0.009 0.4 D:P60881:0.009
C:P60881:0.087
A:P63045:0.339
 HOH
 9.506
 N
 O
ALA H:51 H:240 50.0 0.435 H -63.1 -40.1 NA NA NA
5cch 2 P32851 92.42 1e-36 X-RAY
 2015-08-12 ALA B:51 B:240 49.0 0.426 H -58.0 -44.7 0.0 0.0 0.426 D:P60881:0.017
C:P60881:0.113
A:P63045:0.374
5cci 2 P32851 92.42 1e-36 X-RAY
 2015-08-12 ALA B:51 B:240 49.0 0.426 H -57.5 -42.7 1.0 0.009 0.417 C:P60881:0.096
A:P63045:0.374
5w5c 2 P32851 92.42 1e-36 X-RAY
 2017-08-23 ALA B:51 B:240 62.0 0.539 H -83.0 -17.9 44.0 0.383 0.156 C:P60881:0.157
5w5d 2 P32851 92.42 1e-36 X-RAY
 2017-08-23 ALA B:51 B:240 50.0 0.435 H -105.4 -34.0 35.0 0.304 0.131 C:P60881:0.13
6mti 4 P32851 92.42 1e-36 EM
 2019-04-24 ALA H:51 B:240 49.0 0.426 H -57.5 -42.6 1.0 0.009 0.417 G:P63045:0.365
I:P60881:0.096
ALA L:51 F:240 48.0 0.417 H -57.5 -42.6 0.0 0.0 0.417 K:P63045:0.365
M:P60881:0.104
ALA P:51 J:240 49.0 0.426 H -57.5 -42.7 0.0 0.0 0.426 O:P63045:0.374
Q:P60881:0.104
ALA T:51 N:240 47.0 0.409 H -57.5 -42.7 0.0 0.0 0.409 U:P60881:0.096
S:P63045:0.365
ALA X:51 R:240 48.0 0.417 H -57.6 -42.7 1.0 0.009 0.408 Y:P60881:0.104
W:P63045:0.365
ALA BA:51 V:240 48.0 0.417 H -57.5 -42.7 0.0 0.0 0.417 AA:P63045:0.365
CA:P60881:0.096
1n7s 2 P32851 92.42 1e-36 X-RAY
 2002-12-27 ALA B:52 B:240 47.0 0.409 H -65.0 -37.7 0.0 0.0 0.409 A:P63045:0.365
D:P60881:0.035
C:P60881:0.113
 HOH
 4.841
 O
 O
3rk2 2 P32851 92.06 1e-34 X-RAY
 2011-07-27 ALA B:52 B:240 52.0 0.452 H -64.9 -37.5 39.0 0.339 0.113 C:P60880:0.113
 HOH
 6.497
 C
 O
ALA F:52 F:240 53.0 0.461 H -71.3 -33.8 NA NA NA
3rk3 2 P32851 92.06 1e-34 X-RAY
 2011-07-27 ALA B:52 B:240 57.0 0.496 H -44.0 -33.7 49.0 0.426 0.07 C:P60880:0.07
3rl0 2 P32851 92.06 1e-34 X-RAY
 2011-07-27 ALA B:52 B:240 54.0 0.47 H -53.2 -41.7 48.0 0.417 0.053 C:P60880:0.052
ALA F:52 F:240 55.0 0.478 H -53.7 -40.6 NA NA NA
ALA J:52 J:240 55.0 0.478 H -53.9 -41.3 NA NA NA
ALA N:52 N:240 55.0 0.478 H -55.3 -40.7 NA NA NA
ALA R:52 R:240 55.0 0.478 H -53.9 -41.1 NA NA NA
ALA V:52 V:240 55.0 0.478 H -53.8 -40.8 NA NA NA
ALA Z:52 Z:240 54.0 0.47 H -55.2 -40.8 NA NA NA
ALA DA:52 d:240 55.0 0.478 H -53.4 -42.1 NA NA NA
1kil 2 P32851 91.67 3e-32 X-RAY
 2002-03-13 ALA B:52 B:240 50.0 0.435 H -61.0 -43.9 0.0 0.0 0.435 A:P63045:0.391
D:P60880:0.026
C:P60880:0.122
 MG
HOH
 9.870
5.646
 N
N
 MG
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p61266-f1 1 P61266 100.0 0.0 SER A:239 A:239 64.0 0.557 H -64.9 -34.9
af-q16623-f1 1 Q16623 81.6 2e-161 ALA A:240 A:240 45.0 0.391 H -61.4 -38.1