Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 31004561 . C A CCDS10699.1:NM_052874.3:c.676Gga>Tga_NP_443106.1:p.226G>* Homo sapiens syntaxin 1B (STX1B), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3c98 2 P32851 83.15 8e-149 X-RAY
 2008-03-25 GLY B:239 B:227 24.0 0.32 74.3 175.0 23.0 0.307 0.013 A:P61765:0.013
 HOH
 3.669
 C
 O
4jeh 2 P32851 85.6 6e-145 X-RAY
 2013-07-17 GLY B:204 B:227 28.0 0.373 88.2 175.2 25.0 0.333 0.04 A:P61765:0.04
 HOH
 3.465
 CA
 O
6mdm 3 P32851 82.03 3e-139 EM
 2018-09-19 GLY H:227 I:227 27.0 0.36 H -57.0 -21.0 5.0 0.067 0.293 K:P54921:0.067
G:P60881:0.28
6mdn 3 P32851 82.03 3e-139 EM
 2018-09-19 GLY H:227 I:227 25.0 0.333 H -60.6 -34.1 0.0 0.0 0.333 G:P60881:0.333
6ip1 2 P32851 82.14 3e-137 EM
 2019-04-24 GLY B:228 B:227 37.0 0.493 H -68.9 -6.3 23.0 0.307 0.186 C:P60881:0.187
4jeu 2 P32851 81.4 4e-130 X-RAY
 2013-07-17 GLY B:226 B:227 25.0 0.333 77.5 -179.1 21.0 0.28 0.053 A:P61765:0.053
2m8r 1 P32851 85.85 2e-63 NMR
 2013-11-20 GLY A:48 A:227 7.0 0.093 H -62.0 -32.3 7.0 0.093 0.0
3hd7 2 P32851 85.85 2e-63 X-RAY
 2009-07-14 GLY B:48 B:227 26.0 0.347 H -63.8 -32.1 8.0 0.107 0.24 C:P60881:0.24
A:P63045:0.013
GLY F:48 F:227 24.0 0.32 H -49.8 -36.9 NA NA NA
3ipd 2 P32851 85.85 2e-63 X-RAY
 2009-09-01 GLY B:48 B:227 26.0 0.347 H -67.8 -30.4 9.0 0.12 0.227 C:P60881:0.227
GLY F:48 F:227 26.0 0.347 H -67.7 -30.8 NA NA NA
1sfc 2 P32851 89.02 6e-46 X-RAY
 1998-10-28 GLY B:48 B:227 27.0 0.36 H -60.1 -33.4 8.0 0.107 0.253 C:P60881:0.253
A:P63045:0.013
GLY F:48 F:227 27.0 0.36 H -49.8 -34.5 NA NA NA
GLY J:48 J:227 24.0 0.32 H -59.1 -17.0 NA NA NA
1jth 2 P32851 93.51 3e-45 X-RAY
 2001-11-28 GLY B:37 B:227 25.0 0.333 H -64.3 -33.8 8.0 0.107 0.226 C:P60881:0.227
 HOH
 2.904
 O
 O
GLY D:37 D:227 27.0 0.36 H -63.8 -32.4 10.0 0.133 0.227 A:P60881:0.227
 HOH
 2.828
 O
 O
1hvv 1 P32851 93.33 7e-44 X-RAY
 2001-01-31 GLY A:38 A:227 32.0 0.427 H -64.8 -37.6 7.0 0.093 0.334 C:P32851:0.333
 TAR
HOH
 2.735
3.679
 O
C
 O11
O
GLY B:38 B:227 30.0 0.4 H -57.6 -46.4 16.0 0.213 0.187 A:P32851:0.187
 HOH
 3.611
 C
 O
GLY C:38 C:227 39.0 0.52 H -60.4 -39.2 4.0 0.053 0.467 A:P32851:0.467
 HOH
 3.351
 O
 O
GLY D:38 D:227 26.0 0.347 H -63.5 -29.1 20.0 0.267 0.08 C:P32851:0.08
 HOH
 2.993
 O
 O
2n1t 2 P32851 91.67 4e-41 NMR
 2015-06-03 GLY B:40 B:227 32.0 0.427 H -62.4 -28.9 6.0 0.08 0.347 A:P63045:0.013
E:P21579:0.093
C:P60880:0.267
1urq 2 P32851 91.67 5e-41 X-RAY
 2004-08-26 GLY B:43 B:227 25.0 0.333 H -62.7 -33.9 6.0 0.08 0.253 C:P13795:0.253
A:Q9Z152:0.013
 HOH
 3.052
 O
 O
5kj7 2 P32851 92.42 1e-36 X-RAY
 2016-10-19 GLY B:37 B:227 27.0 0.36 H -63.3 -40.9 8.0 0.107 0.253 A:P63025:0.013
C:P60881:0.253
GLY H:37 H:227 28.0 0.373 H -64.1 -41.4 NA NA NA
5kj8 2 P32851 92.42 1e-36 X-RAY
 2016-10-19 GLY B:37 B:227 26.0 0.347 H -64.0 -48.5 5.0 0.067 0.28 C:P60881:0.28
GLY H:37 H:227 25.0 0.333 H -63.6 -46.8 NA NA NA
6wvw 2 P32851 92.42 1e-36 X-RAY
 2021-03-17 GLY B:37 B:227 27.0 0.36 H -59.1 -36.6 8.0 0.107 0.253 C:P60881:0.253
 HOH
 2.449
 O
 O
GLY F:37 F:227 21.0 0.28 H -58.2 -39.3 NA NA NA
3j96 4 P32851 92.42 1e-36 EM
 2015-01-28 GLY L:38 L:227 20.0 0.267 H -71.1 -10.3 11.0 0.147 0.12 M:None:0.12
K:P63045:0.027
3j97 4 P32851 92.42 1e-36 EM
 2015-01-28 GLY L:38 L:227 28.0 0.373 H -57.4 -50.6 6.0 0.08 0.293 M:None:0.293
3j98 4 P32851 92.42 1e-36 EM
 2015-01-28 GLY L:38 L:227 28.0 0.373 H -60.0 -37.7 4.0 0.053 0.32 M:None:0.32
3j99 4 P32851 92.42 1e-36 EM
 2015-01-28 GLY L:38 L:227 28.0 0.373 H -60.0 -37.8 4.0 0.053 0.32 M:None:0.32
5ccg 2 P32851 92.42 1e-36 X-RAY
 2015-08-12 GLY B:38 B:227 26.0 0.347 H -61.4 -45.9 8.0 0.107 0.24 C:P60881:0.24
A:P63045:0.013
GLY H:38 H:227 27.0 0.36 H -61.8 -44.5 NA NA NA
5cch 2 P32851 92.42 1e-36 X-RAY
 2015-08-12 GLY B:38 B:227 25.0 0.333 H -62.4 -43.6 6.0 0.08 0.253 C:P60881:0.253
A:P63045:0.013
5cci 2 P32851 92.42 1e-36 X-RAY
 2015-08-12 GLY B:38 B:227 26.0 0.347 H -59.7 -46.3 8.0 0.107 0.24 C:P60881:0.24
A:P63045:0.013
5w5c 2 P32851 92.42 1e-36 X-RAY
 2017-08-23 GLY B:38 B:227 28.0 0.373 H -72.0 -27.5 8.0 0.107 0.266 C:P60881:0.267
A:P63045:0.013
 HOH
 3.106
 O
 O
5w5d 2 P32851 92.42 1e-36 X-RAY
 2017-08-23 GLY B:38 B:227 29.0 0.387 H -68.8 -42.3 9.0 0.12 0.267 C:P60881:0.267
A:P63045:0.013
 HOH
 8.912
 CA
 O
6mti 4 P32851 92.42 1e-36 EM
 2019-04-24 GLY H:38 B:227 26.0 0.347 H -59.7 -46.4 7.0 0.093 0.254 G:P63045:0.027
I:P60881:0.253
GLY L:38 F:227 26.0 0.347 H -59.7 -46.3 7.0 0.093 0.254 K:P63045:0.027
M:P60881:0.253
GLY P:38 J:227 26.0 0.347 H -59.7 -46.3 8.0 0.107 0.24 O:P63045:0.027
Q:P60881:0.24
GLY T:38 N:227 25.0 0.333 H -59.7 -46.3 7.0 0.093 0.24 U:P60881:0.24
S:P63045:0.013
GLY X:38 R:227 26.0 0.347 H -59.7 -46.3 6.0 0.08 0.267 Y:P60881:0.267
W:P63045:0.027
GLY BA:38 V:227 27.0 0.36 H -59.6 -46.4 8.0 0.107 0.253 AA:P63045:0.027
CA:P60881:0.253
1n7s 2 P32851 92.42 1e-36 X-RAY
 2002-12-27 GLY B:39 B:227 26.0 0.347 H -67.8 -31.7 8.0 0.107 0.24 C:P60881:0.24
 HOH
 3.017
 O
 O
3rk2 2 P32851 92.06 1e-34 X-RAY
 2011-07-27 GLY B:39 B:227 30.0 0.4 H -55.6 -45.5 9.0 0.12 0.28 C:P60880:0.28
 CA
CA
HOH
 4.146
5.611
3.232
 O
O
O
 CA
CA
O
GLY F:39 F:227 28.0 0.373 H -51.0 -47.0 NA NA NA
3rk3 2 P32851 92.06 1e-34 X-RAY
 2011-07-27 GLY B:39 B:227 34.0 0.453 H -47.4 -44.4 10.0 0.133 0.32 A:P63027:0.04
C:P60880:0.32
3rl0 2 P32851 92.06 1e-34 X-RAY
 2011-07-27 GLY B:39 B:227 25.0 0.333 H -52.8 -34.5 1.0 0.013 0.32 A:P63027:0.027
C:P60880:0.32
GLY F:39 F:227 27.0 0.36 H -53.5 -33.7 NA NA NA
GLY J:39 J:227 24.0 0.32 H -53.4 -35.0 NA NA NA
GLY N:39 N:227 25.0 0.333 H -53.3 -35.4 NA NA NA
GLY R:39 R:227 24.0 0.32 H -53.3 -34.1 NA NA NA
GLY V:39 V:227 24.0 0.32 H -53.0 -33.7 NA NA NA
GLY Z:39 Z:227 26.0 0.347 H -53.6 -35.4 NA NA NA
GLY DA:39 d:227 25.0 0.333 H -53.0 -35.2 NA NA NA
1kil 2 P32851 91.67 3e-32 X-RAY
 2002-03-13 GLY B:39 B:227 24.0 0.32 H -66.0 -21.3 6.0 0.08 0.24 A:P63045:0.013
C:P60880:0.24
 HOH
 2.636
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p61266-f1 1 P61266 100.0 0.0 GLY A:226 A:226 37.0 0.493 H -54.3 -52.0
af-q16623-f1 1 Q16623 81.6 2e-161 GLY A:227 A:227 40.0 0.533 H -55.6 -54.7