Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 31283270 . C A CCDS45470.1:NM_000632.3:c.661Ctg>Atg_NP_000623.2:p.221L>M Homo sapiens integrin subunit alpha M (ITGAM), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6rhw 3 P11215 100.0 2e-133 X-RAY
 2019-12-18 LEU C:79 C:205 32.0 0.188 -85.0 -41.6 12.0 0.071 0.117 A:A0A0D6HCK9:0.118
 DMS
MG
 7.130
9.535
 O
HB2
 H13
MG
1jlm 1 P11215 100.0 2e-131 X-RAY
 1997-01-11 LEU A:79 A:205 28.0 0.165 -80.4 -29.3 28.0 0.165 0.0 HOH
 6.501
 O
 O
4m76 2 P11215 98.97 2e-131 X-RAY
 2013-10-02 LEU B:82 B:205 21.0 0.124 -85.6 -35.3 12.0 0.071 0.053 A:P01024:0.053
 NI
HOH
 9.582
6.124
 C
O
 NI
O
4xw2 1 P11215 98.97 2e-131 X-RAY
 2016-01-13 LEU A:82 A:205 24.0 0.141 -70.1 -39.2 24.0 0.141 0.0 SIM
HOH
 9.341
6.147
 C
N
 O1A
O
1m1u 1 P11215 99.48 2e-131 X-RAY
 2002-08-07 LEU A:85 A:205 26.0 0.153 -74.5 -37.3 26.0 0.153 0.0 HOH
 4.332
 CD2
 O
1na5 1 P11215 100.0 6e-131 X-RAY
 2003-05-20 LEU A:78 A:205 18.0 0.106 -72.4 -39.5 18.0 0.106 0.0 HOH
 2.925
 O
 O
1mf7 1 P11215 99.48 4e-130 X-RAY
 2003-05-20 LEU A:78 A:205 37.0 0.218 -70.8 -38.5 37.0 0.218 0.0 HOH
 3.032
 O
 O
1ido 1 P11215 100.0 3e-129 X-RAY
 1996-08-01 LEU A:79 A:205 29.0 0.171 -70.2 -37.6 29.0 0.171 0.0 HOH
 2.475
 O
 O
3q3g 3 P11215 100.0 3e-129 X-RAY
 2011-11-30 LEU C:74 G:205 51.0 0.3 -74.6 -44.1 7.0 0.041 0.259 B:None:0.259
 GOL
HOH
 8.437
3.259
 CD1
O
 C3
O
LEU F:74 E:205 53.0 0.312 -74.8 -43.6 NA NA NA
LEU I:74 I:205 53.0 0.312 -74.1 -44.0 NA NA NA
LEU L:74 L:205 53.0 0.312 -74.8 -43.6 NA NA NA
1bhq 1 P11215 100.0 2e-128 X-RAY
 1998-11-04 LEU A:73 1:205 36.0 0.212 -85.5 -26.9 36.0 0.212 0.0 HOH
 5.590
 N
 O
LEU B:73 2:505 20.0 0.118 -111.7 -21.5 20.0 0.118 0.0 CD
HOH
 9.643
4.992
 C
N
 CD
O
1bho 1 P11215 100.0 2e-128 X-RAY
 1998-11-04 LEU A:74 1:205 32.0 0.188 -75.4 -23.6 32.0 0.188 0.0 HOH
 5.141
 N
 O
LEU B:74 2:505 30.0 0.176 -102.5 -23.7 30.0 0.176 0.0 HOH
 5.107
 N
 O
1idn 1 P11215 100.0 2e-128 X-RAY
 1998-11-04 LEU A:74 1:205 22.0 0.129 -79.6 -36.2 22.0 0.129 0.0 HOH
 5.230
 N
 O
LEU B:74 2:505 34.0 0.2 -109.5 -20.7 34.0 0.2 0.0 HOH
 3.923
 CD2
 O
3qa3 3 P11215 99.47 6e-128 X-RAY
 2011-11-30 LEU C:74 G:205 55.0 0.324 -73.8 -42.5 6.0 0.035 0.289 B:None:0.288
 EDO
GOL
HOH
 6.659
7.983
6.929
 O
CD1
CD2
 O2
C1
O
LEU F:74 E:205 55.0 0.324 -74.6 -41.8 NA NA NA
LEU I:74 I:205 54.0 0.318 -74.0 -42.3 NA NA NA
LEU L:74 L:205 53.0 0.312 -74.5 -41.9 NA NA NA
1n9z 1 P11215 98.44 5e-127 X-RAY
 2003-05-20 LEU A:78 A:205 39.0 0.229 -69.9 -47.6 39.0 0.229 0.0 MG
 9.989
 N
 MG

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p11215-f1 1 P11215 99.91 0.0 LEU A:221 A:221 39.0 0.229 -84.6 -31.1