Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 68712119 . T A CCDS10868.1:NM_001793.4:c.329gTg>gAg_NP_001784.2:p.110V>E Homo sapiens cadherin 3, type 1, P-cadherin (placental) (CDH3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4zmt 1 P22223 100.0 1e-163 X-RAY
 2016-09-07 VAL A:4 A:3 154.0 0.994 S -68.5 -50.6 63.0 0.406 0.588 B:P22223:0.587
VAL B:4 B:3 152.0 0.981 S -71.4 -56.6 68.0 0.439 0.542 A:P22223:0.542
 HOH
 3.157
 CG2
 O
VAL C:4 C:3 149.0 0.961 S -70.4 -57.1 NA NA NA
VAL D:4 D:3 148.0 0.955 S -71.5 -56.7 NA NA NA
VAL E:4 E:3 150.0 0.968 S -71.0 -58.2 NA NA NA
VAL F:4 F:3 150.0 0.968 S -71.4 -57.1 NA NA NA
4zmn 1 P22223 100.0 1e-163 X-RAY
 2016-09-07 VAL A:3 A:3 95.0 0.613 -137.8 163.7 95.0 0.613 0.0 HOH
 3.556
 CG1
 O
6ztb 1 P22223 100.0 1e-151 X-RAY
 2021-05-05 VAL A:5 I:110 89.0 0.574 -155.3 144.1 89.0 0.574 0.0 HOH
 3.105
 O
 O
6ztr 3 P22223 100.0 1e-151 X-RAY
 2021-05-05 VAL D:5 I:110 138.0 0.89 -147.5 139.6 NA NA NA
VAL E:5 J:110 134.0 0.865 -166.0 143.4 134.0 0.865 0.0 HOH
 6.712
 C
 O
4zmz 1 P22223 100.0 1e-149 X-RAY
 2016-09-07 VAL A:4 A:3 70.0 0.452 -134.9 149.6 70.0 0.452 0.0 HOH
 3.317
 O
 O
7cmf 1 P22223 100.0 1e-149 X-RAY
 2021-09-15 VAL A:4 A:3 113.0 0.729 -138.3 130.6 113.0 0.729 0.0 HOH
 7.956
 C
 O
4zmq 1 P22223 100.0 9e-149 X-RAY
 2016-09-07 VAL A:4 A:3 151.0 0.974 S -68.6 -49.1 68.0 0.439 0.535 B:P22223:0.535
 HOH
 4.772
 N
 O
VAL B:4 B:3 148.0 0.955 S -66.9 -51.3 59.0 0.381 0.574 A:P22223:0.574
 HOH
 3.940
 CB
 O
7cme 1 P22223 100.0 9e-149 X-RAY
 2021-09-15 VAL A:4 A:3 148.0 0.955 S -67.1 -43.1 68.0 0.439 0.516 B:P22223:0.516
VAL B:4 B:3 150.0 0.968 S -59.4 -56.9 64.0 0.413 0.555 A:P22223:0.555
 HOH
 8.105
 O
 O
4oy9 1 P22223 100.0 9e-149 X-RAY
 2015-04-01 VAL A:3 A:3 98.0 0.632 -147.4 160.7 98.0 0.632 0.0 HOH
 2.863
 N
 O
4zml 1 P22223 100.0 9e-149 X-RAY
 2016-09-07 VAL A:3 A:3 97.0 0.626 -142.1 165.9 97.0 0.626 0.0 HOH
 2.703
 O
 O
5jym 1 P22223 100.0 9e-149 X-RAY
 2016-12-28 VAL A:3 A:3 104.0 0.671 -128.3 171.0 35.0 0.226 0.445 C:P22223:0.445
 HOH
 6.657
 CG1
 O
VAL C:3 C:3 101.0 0.652 -131.2 178.9 38.0 0.245 0.407 A:P22223:0.406
 HOH
 4.932
 O
 O
4zmo 1 P22223 99.53 4e-148 X-RAY
 2016-09-07 VAL A:3 A:3 104.0 0.671 -130.9 174.1 38.0 0.245 0.426 A:P22223:0.426
 HOH
 2.521
 O
 O
4zmy 1 P22223 99.53 4e-148 X-RAY
 2016-09-07 VAL A:4 A:3 93.0 0.6 -155.0 154.3 52.0 0.335 0.265 A:P22223:0.265
 HOH
 3.056
 O
 O
4zmp 1 P22223 99.53 2e-147 X-RAY
 2016-09-07 VAL A:3 A:3 100.0 0.645 -136.0 166.6 31.0 0.2 0.445 A:P22223:0.445
 HOH
 2.915
 O
 O
4zmw 1 P22223 99.53 2e-147 X-RAY
 2016-09-07 VAL A:4 A:3 113.0 0.729 -145.4 141.6 113.0 0.729 0.0 HOH
 3.824
 O
 O
VAL B:4 B:3 110.0 0.71 -132.0 153.7 110.0 0.71 0.0 HOH
 8.571
 N
 O
4zmx 1 P22223 99.53 3e-147 X-RAY
 2016-09-07 VAL A:3 NA:NA DO NA DO DO DO NA NA NA
VAL B:3 NA:NA DO NA DO DO DO NA NA NA
4zmv 1 P22223 98.59 5e-146 X-RAY
 2016-09-07 VAL A:4 A:3 133.0 0.858 -86.7 136.2 55.0 0.355 0.503 B:P22223:0.503
 NI
HOH
 9.353
2.663
 N
O
 NI
O
VAL B:4 B:3 135.0 0.871 -77.7 132.1 57.0 0.368 0.503 A:P22223:0.503
 NI
HOH
 9.254
2.652
 N
O
 NI
O
4nqq 1 P10287 88.26 4e-132 X-RAY
 2014-09-24 VAL A:3 A:3 92.0 0.594 -126.8 156.1 33.0 0.213 0.381 B:P10287:0.381
 HOH
 2.689
 O
 O
VAL B:3 B:3 88.0 0.568 -129.0 153.7 33.0 0.213 0.355 A:P10287:0.355
 HOH
 3.976
 HG22
 O
VAL C:3 NA:NA DO NA DO DO DO NA NA NA
VAL D:3 D:3 126.0 0.813 -121.9 139.1 NA NA NA
5jyl 1 P22223 100.0 3e-63 X-RAY
 2016-12-28 VAL A:4 NA:NA DO NA DO DO DO NA NA NA
VAL C:4 NA:NA DO NA DO DO DO NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p22223-f1 1 P22223 100.0 0.0 VAL A:110 A:110 131.0 0.845 -67.6 132.2