Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 68712537 . G A CCDS10868.1:NM_001793.4:c.524cGg>cAg_NP_001784.2:p.175R>Q Homo sapiens cadherin 3, type 1, P-cadherin (placental) (CDH3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4zmt 1 P22223 100.0 1e-163 X-RAY
 2016-09-07 ARG A:69 A:68 46.0 0.204 T -59.9 -35.1 46.0 0.204 0.0 CA
CA
CA
HOH
 4.315
4.426
8.570
9.826
 N
NE
NH2
CD
 CA
CA
CA
O
ARG B:69 B:68 46.0 0.204 T -60.2 -35.7 46.0 0.204 0.0 CA
CA
CA
HOH
 4.219
8.680
4.532
5.355
 N
NH2
NE
N
 CA
CA
CA
O
ARG C:69 C:68 42.0 0.187 T -60.3 -35.4 NA NA NA
ARG D:69 D:68 45.0 0.2 T -59.6 -35.9 NA NA NA
ARG E:69 E:68 47.0 0.209 T -59.6 -36.2 NA NA NA
ARG F:69 F:68 47.0 0.209 T -58.9 -35.9 NA NA NA
4zmn 1 P22223 100.0 1e-163 X-RAY
 2016-09-07 ARG A:68 A:68 45.0 0.2 T -54.3 -37.0 45.0 0.2 0.0 CA
CA
CA
HOH
 4.402
8.704
4.479
4.023
 N
NH2
NE
NH2
 CA
CA
CA
O
6ztb 1 P22223 100.0 1e-151 X-RAY
 2021-05-05 ARG A:70 I:175 56.0 0.249 T -60.5 -33.8 56.0 0.249 0.0 CA
CA
CA
NA
HOH
 8.627
4.100
4.464
5.654
2.762
 NH2
N
NE
NH2
O
 CA
CA
CA
NA
O
6ztr 3 P22223 100.0 1e-151 X-RAY
 2021-05-05 ARG D:70 I:175 49.0 0.218 T -57.7 -37.8 NA NA NA
ARG E:70 J:175 50.0 0.222 T -59.8 -40.4 50.0 0.222 0.0 CA
CA
CA
HOH
 4.484
4.080
8.789
2.760
 NE
N
NH2
NH1
 CA
CA
CA
O
4zmz 1 P22223 100.0 1e-149 X-RAY
 2016-09-07 ARG A:69 A:68 60.0 0.267 T -64.4 -35.1 60.0 0.267 0.0 CA
CA
CA
HOH
 4.486
8.605
4.116
4.538
 NE
NH2
N
CD
 CA
CA
CA
O
7cmf 1 P22223 100.0 1e-149 X-RAY
 2021-09-15 ARG A:69 A:68 56.0 0.249 T -54.5 -33.5 56.0 0.249 0.0 CA
CA
CA
G60
HOH
 4.292
8.566
4.313
2.386
6.674
 NH1
NH1
N
NE
N
 CA
CA
CA
H62
O
4zmq 1 P22223 100.0 9e-149 X-RAY
 2016-09-07 ARG A:69 A:68 46.0 0.204 T -58.1 -39.4 46.0 0.204 0.0 CA
CA
CA
CA
HOH
 4.230
4.413
8.833
6.020
2.748
 N
NE
NH2
O
NH2
 CA
CA
CA
CA
O
ARG B:69 B:68 47.0 0.209 T -58.5 -34.7 47.0 0.209 0.0 CA
CA
CA
HOH
 4.194
4.478
8.804
2.479
 N
NE
NH2
O
 CA
CA
CA
O
7cme 1 P22223 100.0 9e-149 X-RAY
 2021-09-15 ARG A:69 A:68 51.0 0.227 T -56.0 -43.2 51.0 0.227 0.0 G60
CA
CA
CA
HOH
 3.058
8.774
4.471
6.375
4.414
 CD
NH2
NE
N
N
 H11
CA
CA
CA
O
ARG B:69 B:68 48.0 0.213 T -54.1 -44.5 48.0 0.213 0.0 G60
CA
CA
CA
HOH
 5.185
8.667
4.471
6.451
4.486
 CD
NH2
NE
N
N
 H121
CA
CA
CA
O
4oy9 1 P22223 100.0 9e-149 X-RAY
 2015-04-01 ARG A:68 A:68 60.0 0.267 T -56.1 -36.7 60.0 0.267 0.0 CA
CA
CA
HOH
 8.577
4.404
4.078
2.706
 NH2
NE
N
NH1
 CA
CA
CA
O
4zml 1 P22223 100.0 9e-149 X-RAY
 2016-09-07 ARG A:68 A:68 57.0 0.253 T -51.6 -38.0 57.0 0.253 0.0 CA
CA
CA
CA
CL
P6G
CA
P6G
HOH
 4.432
4.227
8.334
8.692
4.439
9.613
8.692
6.714
2.937
 NE
N
NH2
N
CD
N
N
C
NH1
 CA
CA
CA
CA
CL
C9
CA
C14
O
5jym 1 P22223 100.0 9e-149 X-RAY
 2016-12-28 ARG A:68 A:68 54.0 0.24 T -60.5 -31.5 54.0 0.24 0.0 CA
CA
CA
HOH
 4.219
4.389
8.731
4.999
 N
NE
NH2
N
 CA
CA
CA
O
ARG C:68 C:68 47.0 0.209 T -61.8 -31.2 47.0 0.209 0.0 CA
CA
CA
HOH
 4.422
8.826
4.360
2.958
 NE
NH2
N
NH1
 CA
CA
CA
O
4zmo 1 P22223 99.53 4e-148 X-RAY
 2016-09-07 ARG A:68 A:68 60.0 0.267 T -61.9 -28.9 60.0 0.267 0.0 CA
CA
HOH
 4.434
8.499
4.574
 NE
NH2
N
 CA
CA
O
4zmy 1 P22223 99.53 4e-148 X-RAY
 2016-09-07 ARG A:69 A:68 58.0 0.258 T -59.0 -35.0 58.0 0.258 0.0 CA
CA
CA
CA
HOH
 4.463
8.557
4.084
6.294
2.633
 NE
NH2
N
O
O
 CA
CA
CA
CA
O
4zmp 1 P22223 99.53 2e-147 X-RAY
 2016-09-07 ARG A:68 A:68 49.0 0.218 T -74.3 -29.7 49.0 0.218 0.0 CA
CA
CA
HOH
 4.309
4.045
8.301
2.883
 NH2
N
NH2
O
 CA
CA
CA
O
4zmw 1 P22223 99.53 2e-147 X-RAY
 2016-09-07 ARG A:69 A:68 55.0 0.244 T -61.8 -29.7 29.0 0.129 0.115 B:P22223:0.116
 CA
CA
SO4
SO4
NI
SO4
HOH
 4.409
8.506
6.434
7.134
7.880
2.991
4.097
 NE
NH2
C
N
C
NH1
NH1
 CA
CA
O1
O3
NI
O3
O
ARG B:69 B:68 52.0 0.231 T -56.2 -28.8 52.0 0.231 0.0 CA
CA
SO4
SO4
NI
HOH
 4.431
8.838
7.277
6.333
8.095
2.857
 NE
NH2
N
C
C
NH1
 CA
CA
O1
O4
NI
O
4zmx 1 P22223 99.53 3e-147 X-RAY
 2016-09-07 ARG A:68 A:68 44.0 0.196 T -51.1 -42.2 44.0 0.196 0.0 CA
CA
CA
 4.250
4.328
8.753
 N
NE
NH2
 CA
CA
CA
ARG B:68 B:68 45.0 0.2 T -56.3 -36.0 45.0 0.2 0.0 CA
CA
CA
 4.463
4.513
8.625
 N
NE
NH2
 CA
CA
CA
4zmv 1 P22223 98.59 5e-146 X-RAY
 2016-09-07 ARG A:69 A:68 50.0 0.222 T -60.4 -37.7 50.0 0.222 0.0 CA
CA
NI
SO4
SO4
HOH
 8.641
4.389
8.171
6.711
7.054
3.058
 NH2
NE
C
C
N
NH1
 CA
CA
NI
O1
O2
O
ARG B:69 B:68 56.0 0.249 T -60.3 -30.1 56.0 0.249 0.0 CA
CA
NI
SO4
SO4
HOH
 4.657
8.938
8.068
6.994
7.174
4.096
 NE
NH2
C
N
C
CD
 CA
CA
NI
O2
O2
O
4nqq 1 P10287 88.26 4e-132 X-RAY
 2014-09-24 ARG A:68 A:68 27.0 0.12 T -67.7 -33.3 27.0 0.12 0.0 CA
CA
CA
HOH
 3.770
3.658
8.129
4.183
 H
HE
HH21
H
 CA
CA
CA
O
ARG B:68 B:68 26.0 0.116 T -67.9 -33.3 26.0 0.116 0.0 CA
CA
CA
HOH
 3.746
3.738
8.127
2.841
 H
HE
HH21
HH22
 CA
CA
CA
O
ARG C:68 C:68 33.0 0.147 T -67.8 -32.9 NA NA NA
ARG D:68 D:68 12.0 0.053 T -68.7 -33.1 NA NA NA
5jyl 1 P22223 100.0 3e-63 X-RAY
 2016-12-28 ARG A:69 A:68 84.0 0.373 T -63.3 -27.4 84.0 0.373 0.0 HOH
 7.612
 N
 O
ARG C:69 C:68 105.0 0.467 T -63.8 -27.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p22223-f1 1 P22223 100.0 0.0 ARG A:175 A:175 44.0 0.196 H -81.1 -34.4