Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr16 | 68712559 | . | G | A | CCDS10868.1:NM_001793.4:c.546gaG>gaA_NP_001784.2:p.182E>E | Homo sapiens cadherin 3, type 1, P-cadherin (placental) (CDH3), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
4zmt | 1 | P22223 | 100.0 | 1e-163 |
X-RAY |
2016-09-07 | GLU | A:76 | A:75 | 77.0 | 0.405 | E | -122.3 | 107.5 | 77.0 | 0.405 | 0.0 | ||||||
GLU | B:76 | B:75 | 77.0 | 0.405 | E | -122.7 | 108.3 | 77.0 | 0.405 | 0.0 |
HOH |
2.781 |
N |
O |
|||||||||
GLU | C:76 | C:75 | 78.0 | 0.411 | E | -122.5 | 108.2 | NA | NA | NA | |||||||||||||
GLU | D:76 | D:75 | 72.0 | 0.379 | E | -122.1 | 107.9 | NA | NA | NA | |||||||||||||
GLU | E:76 | E:75 | 70.0 | 0.368 | E | -122.7 | 107.8 | NA | NA | NA | |||||||||||||
GLU | F:76 | F:75 | 64.0 | 0.337 | E | -123.1 | 107.8 | NA | NA | NA | |||||||||||||
4zmn | 1 | P22223 | 100.0 | 1e-163 |
X-RAY |
2016-09-07 | GLU | A:75 | A:75 | 90.0 | 0.474 | E | -131.2 | 122.3 | 26.0 | 0.137 | 0.337 |
A:P22223:0.337 |
HOH |
2.761 |
O |
O |
|
6ztb | 1 | P22223 | 100.0 | 1e-151 |
X-RAY |
2021-05-05 | GLU | A:77 | I:182 | 68.0 | 0.358 | E | -125.0 | 105.6 | 68.0 | 0.358 | 0.0 |
HOH |
2.712 |
O |
O |
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6ztr | 3 | P22223 | 100.0 | 1e-151 |
X-RAY |
2021-05-05 | GLU | D:77 | I:182 | 65.0 | 0.342 | E | -125.8 | 110.2 | NA | NA | NA | ||||||
GLU | E:77 | J:182 | 65.0 | 0.342 | E | -126.1 | 110.0 | 65.0 | 0.342 | 0.0 |
HOH |
2.753 |
O |
O |
|||||||||
4zmz | 1 | P22223 | 100.0 | 1e-149 |
X-RAY |
2016-09-07 | GLU | A:76 | A:75 | 83.0 | 0.437 | E | -117.5 | 111.2 | 83.0 | 0.437 | 0.0 |
HOH |
6.562 |
O |
O |
||
7cmf | 1 | P22223 | 100.0 | 1e-149 |
X-RAY |
2021-09-15 | GLU | A:76 | A:75 | 61.0 | 0.321 | E | -128.1 | 96.7 | 61.0 | 0.321 | 0.0 |
HOH |
2.145 |
OE2 |
O |
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4zmq | 1 | P22223 | 100.0 | 9e-149 |
X-RAY |
2016-09-07 | GLU | A:76 | A:75 | 80.0 | 0.421 | E | -125.8 | 108.1 | 80.0 | 0.421 | 0.0 |
HOH |
2.906 |
N |
O |
||
GLU | B:76 | B:75 | 79.0 | 0.416 | E | -126.0 | 106.3 | 79.0 | 0.416 | 0.0 |
HOH |
2.869 |
OE1 |
O |
|||||||||
7cme | 1 | P22223 | 100.0 | 9e-149 |
X-RAY |
2021-09-15 | GLU | A:76 | A:75 | 79.0 | 0.416 | E | -125.4 | 104.5 | 79.0 | 0.416 | 0.0 |
G60 |
9.776 |
OE1 |
H111 |
||
GLU | B:76 | B:75 | 81.0 | 0.426 | E | -124.8 | 106.8 | 81.0 | 0.426 | 0.0 |
G60 HOH |
9.384 6.613 |
OE1 OE2 |
CL O |
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4oy9 | 1 | P22223 | 100.0 | 9e-149 |
X-RAY |
2015-04-01 | GLU | A:75 | A:75 | 107.0 | 0.563 | E | -124.6 | 106.7 | 107.0 | 0.563 | 0.0 |
HOH |
2.936 |
N |
O |
||
4zml | 1 | P22223 | 100.0 | 9e-149 |
X-RAY |
2016-09-07 | GLU | A:75 | A:75 | 115.0 | 0.605 | E | -124.9 | 103.5 | 115.0 | 0.605 | 0.0 |
HOH |
2.667 |
OE2 |
O |
||
5jym | 1 | P22223 | 100.0 | 9e-149 |
X-RAY |
2016-12-28 | GLU | A:75 | A:75 | 72.0 | 0.379 | E | -127.9 | 117.0 | 72.0 | 0.379 | 0.0 |
HOH |
4.671 |
N |
O |
||
GLU | C:75 | C:75 | 64.0 | 0.337 | E | -126.0 | 115.0 | 64.0 | 0.337 | 0.0 |
HOH |
6.845 |
O |
O |
|||||||||
4zmo | 1 | P22223 | 99.53 | 4e-148 |
X-RAY |
2016-09-07 | GLU | A:75 | A:75 | 81.0 | 0.426 | E | -113.3 | 109.3 | 81.0 | 0.426 | 0.0 |
HOH |
6.912 |
OE1 |
O |
||
4zmy | 1 | P22223 | 99.53 | 4e-148 |
X-RAY |
2016-09-07 | GLU | A:76 | A:75 | 77.0 | 0.405 | E | -128.9 | 107.7 | 77.0 | 0.405 | 0.0 |
HOH |
2.828 |
O |
O |
||
4zmp | 1 | P22223 | 99.53 | 2e-147 |
X-RAY |
2016-09-07 | GLU | A:75 | A:75 | 107.0 | 0.563 | E | -131.6 | 111.4 | 107.0 | 0.563 | 0.0 |
HOH |
2.850 |
O |
O |
||
4zmw | 1 | P22223 | 99.53 | 2e-147 |
X-RAY |
2016-09-07 | GLU | A:76 | A:75 | 60.0 | 0.316 | E | -114.9 | 118.2 | 60.0 | 0.316 | 0.0 |
HOH |
2.863 |
N |
O |
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GLU | B:76 | B:75 | 63.0 | 0.332 | E | -113.9 | 101.9 | 63.0 | 0.332 | 0.0 | |||||||||||||
4zmx | 1 | P22223 | 99.53 | 3e-147 |
X-RAY |
2016-09-07 | GLU | A:75 | A:75 | 77.0 | 0.405 | E | -127.8 | 98.9 | 77.0 | 0.405 | 0.0 | ||||||
GLU | B:75 | B:75 | 84.0 | 0.442 | E | -122.8 | 96.1 | 84.0 | 0.442 | 0.0 | |||||||||||||
4zmv | 1 | P22223 | 98.59 | 5e-146 |
X-RAY |
2016-09-07 | GLU | A:76 | A:75 | 81.0 | 0.426 | E | -122.9 | 105.1 | 81.0 | 0.426 | 0.0 |
HOH |
2.909 |
N |
O |
||
GLU | B:76 | B:75 | 69.0 | 0.363 | E | -126.4 | 109.6 | 69.0 | 0.363 | 0.0 |
HOH |
2.874 |
N |
O |
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4nqq | 1 | P10287 | 88.26 | 4e-132 |
X-RAY |
2014-09-24 | GLU | A:75 | A:75 | 65.0 | 0.342 | E | -118.8 | 96.1 | 65.0 | 0.342 | 0.0 | ||||||
GLU | B:75 | B:75 | 59.0 | 0.311 | E | -118.2 | 96.7 | 59.0 | 0.311 | 0.0 |
HOH |
3.410 |
HB3 |
O |
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GLU | C:75 | C:75 | 69.0 | 0.363 | E | -118.3 | 97.5 | NA | NA | NA | |||||||||||||
GLU | D:75 | D:75 | 61.0 | 0.321 | E | -116.6 | 96.0 | NA | NA | NA | |||||||||||||
5jyl | 1 | P22223 | 100.0 | 3e-63 |
X-RAY |
2016-12-28 | GLU | A:76 | A:75 | 88.0 | 0.463 | E | -123.4 | 114.5 | 88.0 | 0.463 | 0.0 | ||||||
GLU | C:76 | C:75 | 79.0 | 0.416 | E | -123.5 | 114.5 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p22223-f1 | 1 | P22223 | 100.0 | 0.0 | GLU | A:182 | A:182 | 88.0 | 0.463 | E | -120.5 | 107.7 |