Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 75239279 . C A CCDS32489.1:NM_001025200.3:c.448Gcg>Tcg_NP_001020371.3:p.150A>S Homo sapiens chymotrypsinogen B2 (CTRB2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1acb 1 P00766 80.82 1e-146 X-RAY
 1993-10-31 ALA A:132 E:132 60.0 0.522 T -66.5 141.3 60.0 0.522 0.0 HOH
 4.070
 N
 O
1cgi 1 P00766 80.82 1e-146 X-RAY
 1993-10-31 ALA A:132 E:132 61.0 0.53 T -70.7 139.3 61.0 0.53 0.0 HOH
 5.863
 CB
 O
1cgj 1 P00766 80.82 1e-146 X-RAY
 1993-10-31 ALA A:132 E:132 61.0 0.53 T -66.1 146.2 61.0 0.53 0.0 HOH
 6.342
 CB
 O
1chg 1 P00766 80.82 1e-146 X-RAY
 1976-11-22 ALA A:132 A:132 61.0 0.53 T -73.7 154.3 61.0 0.53 0.0
1ex3 1 P00766 80.82 1e-146 X-RAY
 2000-05-17 ALA A:132 A:132 63.0 0.548 T -66.7 149.2 63.0 0.548 0.0 HOH
 4.575
 N
 O
1gcd 1 P00766 80.82 1e-146 X-RAY
 1994-06-22 ALA A:132 A:132 60.0 0.522 T -64.8 135.0 60.0 0.522 0.0 HOH
 2.533
 O
 O
1gl0 1 P00766 80.82 1e-146 X-RAY
 2001-11-28 ALA A:132 E:132 55.0 0.478 T -66.5 154.0 55.0 0.478 0.0 HOH
 3.468
 CB
 O
1gl1 1 P00766 80.82 1e-146 X-RAY
 2001-11-28 ALA A:132 A:132 60.0 0.522 T -60.9 143.8 60.0 0.522 0.0 HOH
 3.878
 CB
 O
ALA B:132 B:132 59.0 0.513 T -62.2 139.4 NA NA NA
ALA C:132 C:132 59.0 0.513 T -60.9 144.7 NA NA NA
1k2i 1 P00766 80.82 1e-146 X-RAY
 2001-12-05 ALA A:132 1:132 60.0 0.522 T -63.9 142.3 60.0 0.522 0.0 HOH
 3.044
 N
 O
1oxg 1 P00766 80.82 1e-146 X-RAY
 2004-05-18 ALA A:132 A:132 59.0 0.513 T -57.6 137.4 59.0 0.513 0.0 HOH
 3.341
 O
 O
1p2m 1 P00766 80.82 1e-146 X-RAY
 2004-04-20 ALA A:132 A:132 60.0 0.522 T -62.0 144.7 60.0 0.522 0.0 HOH
 3.934
 CB
 O
ALA C:132 C:132 61.0 0.53 T -65.0 143.0 NA NA NA
1p2n 1 P00766 80.82 1e-146 X-RAY
 2004-04-20 ALA A:132 A:132 60.0 0.522 T -62.3 143.9 60.0 0.522 0.0 HOH
 3.042
 N
 O
ALA C:132 C:132 61.0 0.53 T -61.2 142.7 NA NA NA
1p2o 1 P00766 80.82 1e-146 X-RAY
 2004-04-20 ALA A:132 A:132 60.0 0.522 T -61.2 141.3 60.0 0.522 0.0 HOH
 3.908
 CB
 O
ALA C:132 C:132 59.0 0.513 T -63.2 148.5 NA NA NA
1p2q 1 P00766 80.82 1e-146 X-RAY
 2004-04-20 ALA A:132 A:132 59.0 0.513 T -64.5 140.9 59.0 0.513 0.0 HOH
 2.979
 N
 O
ALA C:132 C:132 61.0 0.53 T -64.6 141.6 NA NA NA
1t7c 1 P00766 80.82 1e-146 X-RAY
 2005-03-08 ALA A:132 A:132 60.0 0.522 T -62.8 146.8 60.0 0.522 0.0 HOH
 2.973
 N
 O
ALA C:132 C:132 63.0 0.548 T -64.3 141.6 NA NA NA
1t8l 1 P00766 80.82 1e-146 X-RAY
 2005-03-08 ALA A:132 A:132 59.0 0.513 T -64.2 144.6 59.0 0.513 0.0 HOH
 3.011
 N
 O
ALA C:132 C:132 62.0 0.539 T -64.6 142.3 NA NA NA
1t8m 1 P00766 80.82 1e-146 X-RAY
 2005-03-08 ALA A:132 A:132 59.0 0.513 T -64.9 145.0 59.0 0.513 0.0 HOH
 3.047
 O
 O
ALA C:132 C:132 64.0 0.557 T -66.1 144.8 NA NA NA
1t8n 1 P00766 80.82 1e-146 X-RAY
 2005-03-08 ALA A:132 A:132 61.0 0.53 T -66.9 142.5 61.0 0.53 0.0 HOH
 2.979
 N
 O
ALA C:132 C:132 60.0 0.522 T -64.3 142.6 NA NA NA
1t8o 1 P00766 80.82 1e-146 X-RAY
 2005-03-08 ALA A:132 A:132 58.0 0.504 T -63.1 144.8 58.0 0.504 0.0 HOH
 2.941
 N
 O
ALA C:132 C:132 59.0 0.513 T -65.8 145.0 NA NA NA
2cga 1 P00766 80.82 1e-146 X-RAY
 1987-04-16 ALA A:132 A:132 66.0 0.574 T -57.2 136.7 66.0 0.574 0.0 HOH
 4.077
 CB
 O
ALA B:132 B:132 65.0 0.565 T -55.8 128.5 65.0 0.565 0.0 HOH
 3.798
 CB
 O
2y6t 1 P00766 80.82 1e-146 X-RAY
 2011-04-20 ALA A:132 A:132 58.0 0.504 T -57.0 143.7 58.0 0.504 0.0 HOH
 3.911
 CB
 O
ALA B:132 B:132 61.0 0.53 T -71.5 149.6 61.0 0.53 0.0
ALA C:132 C:132 62.0 0.539 T -68.4 150.7 NA NA NA
ALA D:132 D:132 60.0 0.522 T -58.6 139.6 NA NA NA
3t62 1 P00766 80.82 1e-146 X-RAY
 2012-08-01 ALA A:132 A:132 64.0 0.557 T -52.5 141.7 64.0 0.557 0.0 HOH
 2.658
 O
 O
ALA C:132 B:132 61.0 0.53 T -63.7 137.1 NA NA NA
ALA E:132 C:132 61.0 0.53 T -60.7 139.9 NA NA NA
4q2k 1 P00766 80.82 1e-146 X-RAY
 2014-07-23 ALA A:132 A:132 55.0 0.478 T -59.5 140.3 55.0 0.478 0.0 HOH
 4.033
 CB
 O
ALA B:132 B:132 59.0 0.513 T -61.2 143.6 NA NA NA
ALA C:132 C:132 57.0 0.496 T -49.6 142.8 NA NA NA
ALA D:132 D:132 58.0 0.504 T -51.6 137.6 58.0 0.504 0.0 HOH
 3.460
 CB
 O
5j4q 1 P00766 80.82 1e-146 X-RAY
 2017-04-12 ALA A:132 A:132 63.0 0.548 T -55.1 127.9 63.0 0.548 0.0 HOH
 5.880
 N
 O
5j4s 1 P00766 80.82 1e-146 X-RAY
 2017-04-12 ALA A:132 A:132 61.0 0.53 T -43.8 136.9 61.0 0.53 0.0 HOH
 2.191
 H
 O
7kty 1 P00766 80.82 1e-146 X-RAY
 2021-03-10 ALA A:132 A:132 62.0 0.539 T -53.1 139.5 62.0 0.539 0.0 HOH
 2.978
 N
 O
7ktz 1 P00766 80.82 1e-146 X-RAY
 2021-03-10 ALA A:132 A:132 59.0 0.513 T -52.5 141.8 59.0 0.513 0.0 HOH
 2.867
 O
 O
7ku0 1 P00766 80.82 1e-146 X-RAY
 2021-03-10 ALA A:132 A:132 60.0 0.522 T -56.0 141.4 60.0 0.522 0.0 HOH
 2.749
 O
 O
7ku1 1 P00766 80.82 1e-146 X-RAY
 2021-03-10 ALA A:132 A:132 59.0 0.513 T -53.2 140.0 59.0 0.513 0.0
7ku2 1 P00766 80.82 1e-146 X-RAY
 2021-03-10 ALA A:132 A:132 65.0 0.565 T -59.3 142.5 65.0 0.565 0.0 HOH
 3.893
 CB
 O
7ku3 1 P00766 80.82 1e-146 X-RAY
 2021-03-10 ALA A:132 A:132 59.0 0.513 T -52.1 141.1 59.0 0.513 0.0 HOH
 3.124
 N
 O
1kdq 1 P07338 89.31 3e-84 X-RAY
 2003-06-10 PRO A:117 A:132 138.0 0.952 T -64.7 130.2 86.0 0.593 0.359 B:P07338:0.359
 HOH
 4.821
 N
 O
2jet 2 P07338 89.84 6e-83 X-RAY
 2007-09-18 PRO B:114 B:132 137.0 0.945 T -56.3 138.5 76.0 0.524 0.421 C:P07338:0.421
 HOH
 4.241
 CB
 O
1ab9 2 P00766 83.21 3e-76 X-RAY
 1997-08-20 ALA B:117 B:132 107.0 0.93 T -62.2 143.7 58.0 0.504 0.426 C:P00766:0.426
 HOH
 4.215
 CB
 O
1afq 2 P00766 83.21 3e-76 X-RAY
 1997-09-17 ALA B:117 B:132 108.0 0.939 T -58.4 141.6 58.0 0.504 0.435 C:P00766:0.435
 HOH
 2.526
 O
 O
1ca0 2 P00766 83.21 3e-76 X-RAY
 1997-07-23 ALA B:117 B:132 110.0 0.957 T -61.0 134.5 62.0 0.539 0.418 C:P00766:0.417
 HOH
 2.977
 N
 O
ALA F:117 G:132 105.0 0.913 T -54.8 155.0 NA NA NA
1cbw 2 P00766 83.21 3e-76 X-RAY
 1997-07-23 ALA B:117 B:132 112.0 0.974 T -71.6 125.5 61.0 0.53 0.444 C:P00766:0.443
 HOH
 3.824
 CB
 O
ALA F:117 G:132 107.0 0.93 T -80.8 132.5 NA NA NA
1cho 2 P00766 83.21 3e-76 X-RAY
 1988-07-16 ALA B:117 F:132 108.0 0.939 T -61.4 141.1 60.0 0.522 0.417 C:P00766:0.417
 HOH
 3.162
 CB
 O
1gct 2 P00766 83.21 3e-76 X-RAY
 1991-10-15 ALA B:117 B:132 109.0 0.948 T -60.3 140.9 60.0 0.522 0.426 C:P00766:0.426
 HOH
 4.138
 N
 O
1gg6 2 P00766 83.21 3e-76 X-RAY
 2000-09-20 ALA B:117 B:132 108.0 0.939 T -63.7 139.2 60.0 0.522 0.417 C:P00766:0.417
 SO4
HOH
 3.824
2.636
 N
O
 O4
O
1ggd 2 P00766 83.21 3e-76 X-RAY
 2000-09-20 ALA B:117 B:132 108.0 0.939 T -62.4 140.8 58.0 0.504 0.435 C:P00766:0.435
 HOH
 2.895
 N
 O
1gha 2 P00766 83.21 3e-76 X-RAY
 1994-06-22 ALA B:117 F:132 111.0 0.965 T -65.1 139.3 60.0 0.522 0.443 C:P00766:0.443
 HOH
 5.005
 N
 O
1ghb 2 P00766 83.21 3e-76 X-RAY
 1994-06-22 ALA B:117 F:132 105.0 0.913 T -67.3 153.6 58.0 0.504 0.409 C:P00766:0.409
 HOH
 5.579
 O
 O
1gmc 2 P00766 83.21 3e-76 X-RAY
 1993-10-31 ALA B:117 F:132 107.0 0.93 T -59.9 141.7 60.0 0.522 0.408 C:P00766:0.409
 HOH
 6.173
 N
 O
1gmd 2 P00766 83.21 3e-76 X-RAY
 1993-10-31 ALA B:117 F:132 108.0 0.939 T -64.7 143.1 59.0 0.513 0.426 C:P00766:0.426
 HOH
 6.097
 N
 O
1gmh 2 P00766 83.21 3e-76 X-RAY
 1994-09-30 ALA B:117 F:132 106.0 0.922 T -61.1 143.3 57.0 0.496 0.426 C:P00766:0.426
 HOH
 3.330
 N
 O
1hja 2 P00766 83.21 3e-76 X-RAY
 1998-01-14 ALA B:117 B:132 103.0 0.896 T -68.6 153.8 58.0 0.504 0.392 C:P00766:0.391
 HOH
 4.054
 CB
 O
1mtn 2 P00766 83.21 3e-76 X-RAY
 1996-08-17 ALA B:117 B:132 108.0 0.939 T -65.9 135.9 60.0 0.522 0.417 C:P00766:0.417
 HOH
 7.062
 CB
 O
ALA F:117 F:132 105.0 0.913 T -51.0 142.3 NA NA NA
1n8o 2 P00766 83.21 3e-76 X-RAY
 2002-12-18 ALA B:117 B:132 107.0 0.93 T -62.8 140.9 59.0 0.513 0.417 C:P00766:0.417
 HOH
 5.212
 O
 O
1vgc 2 P00766 83.21 3e-76 X-RAY
 1997-11-12 ALA B:117 B:132 109.0 0.948 T -64.1 138.0 63.0 0.548 0.4 C:P00766:0.4
 HOH
 4.836
 N
 O
1yph 2 P00766 83.21 3e-76 X-RAY
 2006-02-14 ALA B:117 C:132 110.0 0.957 T -53.5 137.3 61.0 0.53 0.427 C:P00766:0.426
 HOH
 2.759
 O
 O
ALA E:117 D:132 107.0 0.93 T -54.5 137.2 59.0 0.513 0.417 F:P00766:0.417
 HOH
 2.810
 O
 O
2cha 2 P00766 83.21 3e-76 X-RAY
 1977-01-18 ALA B:117 B:132 107.0 0.93 T -61.4 151.7 50.0 0.435 0.495 C:P00766:0.496
ALA E:117 F:132 108.0 0.939 T -61.4 151.7 50.0 0.435 0.504 F:P00766:0.504
2gch 2 P00766 83.21 3e-76 X-RAY
 1980-07-09 ALA B:117 F:132 111.0 0.965 T -63.6 143.7 61.0 0.53 0.435 C:P00766:0.435
 HOH
 4.514
 CB
 O
2gct 2 P00766 83.21 3e-76 X-RAY
 1991-10-15 ALA B:117 B:132 110.0 0.957 T -61.1 140.6 63.0 0.548 0.409 C:P00766:0.409
 HOH
 3.981
 CB
 O
2gmt 2 P00766 83.21 3e-76 X-RAY
 1994-11-01 ALA B:117 B:132 113.0 0.983 T -59.1 130.4 64.0 0.557 0.426 C:P00766:0.426
 HOH
 2.574
 O
 O
2p8o 2 P00766 83.21 3e-76 X-RAY
 2007-05-08 ALA B:117 B:132 110.0 0.957 T -60.4 141.0 57.0 0.496 0.461 C:P00766:0.461
 HOH
 2.761
 N
 O
2vgc 2 P00766 83.21 3e-76 X-RAY
 1997-11-12 ALA B:117 B:132 109.0 0.948 T -65.7 137.7 62.0 0.539 0.409 C:P00766:0.409
 HOH
 3.247
 N
 O
3bg4 2 P00766 83.21 3e-76 X-RAY
 2008-07-29 ALA B:117 B:132 105.0 0.913 T -59.0 151.7 55.0 0.478 0.435 C:P00766:0.435
 HOH
 4.294
 CB
 O
3gch 2 P00766 83.21 3e-76 X-RAY
 1990-10-15 ALA B:117 B:132 110.0 0.957 T -66.6 136.3 61.0 0.53 0.427 C:P00766:0.426
 HOH
 6.365
 CB
 O
3gct 2 P00766 83.21 3e-76 X-RAY
 1991-10-15 ALA B:117 F:132 109.0 0.948 T -56.8 142.2 60.0 0.522 0.426 C:P00766:0.426
 HOH
 4.198
 CB
 O
3ru4 4 P00766 83.21 3e-76 X-RAY
 2012-08-29 ALA D:117 D:132 107.0 0.93 T -47.2 136.0 NA NA NA
3vgc 2 P00766 83.21 3e-76 X-RAY
 1997-11-12 ALA B:117 B:132 109.0 0.948 T -62.5 140.6 61.0 0.53 0.418 C:P00766:0.417
 HOH
 3.116
 N
 O
4cha 2 P00766 83.21 3e-76 X-RAY
 1985-04-01 ALA B:117 B:132 110.0 0.957 T -58.0 135.1 60.0 0.522 0.435 C:P00766:0.435
 HOH
 8.514
 N
 O
ALA E:117 F:132 109.0 0.948 T -61.7 140.3 47.0 0.409 0.539 F:P00766:0.539
 HOH
 8.526
 N
 O
4gch 2 P00766 83.21 3e-76 X-RAY
 1990-10-15 ALA B:117 F:132 112.0 0.974 T -64.2 130.2 61.0 0.53 0.444 C:P00766:0.443
 HOH
 6.384
 CB
 O
4vgc 2 P00766 83.21 3e-76 X-RAY
 1997-11-12 ALA B:117 B:132 108.0 0.939 T -59.9 137.4 58.0 0.504 0.435 C:P00766:0.435
 HOH
 4.676
 N
 O
5cha 2 P00766 83.21 3e-76 X-RAY
 1985-04-01 ALA B:117 B:132 109.0 0.948 T -49.3 129.0 54.0 0.47 0.478 C:P00766:0.478
 HOH
 3.860
 CB
 O
ALA E:117 F:132 110.0 0.957 T -58.4 131.4 58.0 0.504 0.453 F:P00766:0.452
 HOH
 3.802
 CB
 O
5gch 2 P00766 83.21 3e-76 X-RAY
 1990-10-15 ALA B:117 F:132 108.0 0.939 T -49.0 145.5 57.0 0.496 0.443 C:P00766:0.443
 HOH
 6.492
 CB
 O
5r42 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:117 B:132 110.0 0.957 T -53.3 139.4 60.0 0.522 0.435 C:P00766:0.435
 HOH
 2.906
 N
 O
5r43 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:117 B:132 110.0 0.957 T -49.9 137.2 58.0 0.504 0.453 C:P00766:0.452
 HOH
 2.917
 N
 O
5r44 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:117 B:132 109.0 0.948 T -53.1 138.9 61.0 0.53 0.418 C:P00766:0.417
 HOH
 2.001
 O
 O
5r45 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:117 B:132 107.0 0.93 T -53.2 137.4 58.0 0.504 0.426 C:P00766:0.426
 HOH
 2.619
 O
 O
5r46 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:117 B:132 110.0 0.957 T -53.2 138.3 62.0 0.539 0.418 C:P00766:0.417
 HOH
 2.905
 N
 O
5r47 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:117 B:132 110.0 0.957 T -50.0 136.5 58.0 0.504 0.453 C:P00766:0.452
 HOH
 2.917
 N
 O
5r48 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:117 B:132 110.0 0.957 T -52.7 138.5 62.0 0.539 0.418 C:P00766:0.417
 HOH
 2.897
 N
 O
5r49 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:117 B:132 110.0 0.957 T -50.3 136.9 58.0 0.504 0.453 C:P00766:0.452
 HOH
 2.914
 N
 O
5r4a 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:117 B:132 110.0 0.957 T -54.5 138.9 63.0 0.548 0.409 C:P00766:0.409
 HOH
 2.574
 O
 O
5r4b 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:117 B:132 111.0 0.965 T -52.8 136.4 60.0 0.522 0.443 C:P00766:0.443
 HOH
 2.928
 N
 O
5r4c 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:117 B:132 109.0 0.948 T -54.5 138.6 64.0 0.557 0.391 C:P00766:0.391
 HOH
 2.672
 O
 O
5r4d 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:117 B:132 110.0 0.957 T -52.7 136.5 62.0 0.539 0.418 C:P00766:0.417
 HOH
 2.856
 N
 O
6cha 2 P00766 83.21 3e-76 X-RAY
 1987-04-16 ALA B:117 B:132 110.0 0.957 T -57.7 130.9 57.0 0.496 0.461 C:P00766:0.461
 HOH
 5.676
 N
 O
ALA E:117 F:132 111.0 0.965 T -63.4 112.9 63.0 0.548 0.417 F:P00766:0.417
 HOH
 4.590
 CB
 O
6di8 2 P00766 83.21 3e-76 X-RAY
 2019-01-23 ALA B:117 B:132 110.0 0.957 T -58.5 140.7 57.0 0.496 0.461 C:P00766:0.461
 HOH
 3.081
 N
 O
ALA E:117 E:132 110.0 0.957 T -59.0 141.1 NA NA NA
ALA H:117 H:132 109.0 0.948 T -58.9 140.7 NA NA NA
ALA K:117 K:132 109.0 0.948 T -58.8 142.0 NA NA NA
6gch 2 P00766 83.21 3e-76 X-RAY
 1990-10-15 ALA B:117 F:132 102.0 0.887 T -55.4 159.2 55.0 0.478 0.409 C:P00766:0.409
 HOH
 3.405
 N
 O
7gch 2 P00766 83.21 3e-76 X-RAY
 1990-10-15 ALA B:117 F:132 107.0 0.93 T -74.8 139.3 19.0 0.165 0.765 B:P00766:0.287
C:P00766:0.391
C:P00766:0.209
 HOH
 1.992
 O
 O
7jrx 2 P00766 83.21 3e-76 X-RAY
 2021-07-21 ALA B:117 B:132 107.0 0.93 T -44.3 135.6 60.0 0.522 0.408 C:P00766:0.409
 HOH
 2.670
 O
 O
ALA F:117 b:132 109.0 0.948 T -49.5 136.5 NA NA NA
8gch 2 P00766 83.21 3e-76 X-RAY
 1992-04-15 ALA B:117 F:132 108.0 0.939 T -55.4 136.2 57.0 0.496 0.443 C:P00766:0.443
 HOH
 2.400
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q6gpi1-f1 1 Q6GPI1 100.0 0.0 ALA A:150 A:150 57.0 0.496 T -58.5 140.5
af-p17538-f1 1 P17538 95.82 0.0 ALA A:150 A:150 56.0 0.487 T -60.0 138.8