Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 75239312 . C A CCDS32489.1:NM_001025200.3:c.415Gtg>Ttg_NP_001020371.3:p.139V>L Homo sapiens chymotrypsinogen B2 (CTRB2), mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1acb 1 P00766 80.82 1e-146 X-RAY
1993-10-31 VAL A:121 E:121 2.0 0.013 -90.5 155.5 2.0 0.013 0.0 HOH
5.091
N
O
1cgi 1 P00766 80.82 1e-146 X-RAY
1993-10-31 VAL A:121 E:121 2.0 0.013 -92.9 146.6 2.0 0.013 0.0 HOH
5.657
N
O
1cgj 1 P00766 80.82 1e-146 X-RAY
1993-10-31 VAL A:121 E:121 3.0 0.019 -96.2 151.2 3.0 0.019 0.0 HOH
6.514
CG2
O
1chg 1 P00766 80.82 1e-146 X-RAY
1976-11-22 VAL A:121 A:121 2.0 0.013 -83.5 164.9 2.0 0.013 0.0
1ex3 1 P00766 80.82 1e-146 X-RAY
2000-05-17 VAL A:121 A:121 2.0 0.013 -90.0 168.4 2.0 0.013 0.0 HOH
2.941
O
O
1gcd 1 P00766 80.82 1e-146 X-RAY
1994-06-22 VAL A:121 A:121 2.0 0.013 -91.5 157.9 2.0 0.013 0.0 HOH
2.818
O
O
1gl0 1 P00766 80.82 1e-146 X-RAY
2001-11-28 VAL A:121 E:121 1.0 0.006 -94.0 155.8 1.0 0.006 0.0 CD
HOH
9.309
4.136
O
O
CD
O
1gl1 1 P00766 80.82 1e-146 X-RAY
2001-11-28 VAL A:121 A:121 2.0 0.013 -93.8 153.2 2.0 0.013 0.0 HOH
2.750
O
O
VAL B:121 B:121 2.0 0.013 -97.8 155.2 NA NA NA
VAL C:121 C:121 2.0 0.013 -94.5 156.3 NA NA NA
1k2i 1 P00766 80.82 1e-146 X-RAY
2001-12-05 VAL A:121 1:121 3.0 0.019 -94.8 157.2 3.0 0.019 0.0 HOH
2.785
O
O
1oxg 1 P00766 80.82 1e-146 X-RAY
2004-05-18 VAL A:121 A:121 1.0 0.006 -91.7 157.0 1.0 0.006 0.0 HOH
4.956
N
O
1p2m 1 P00766 80.82 1e-146 X-RAY
2004-04-20 VAL A:121 A:121 2.0 0.013 -94.6 156.3 2.0 0.013 0.0 HOH
2.741
O
O
VAL C:121 C:121 2.0 0.013 -98.6 155.5 NA NA NA
1p2n 1 P00766 80.82 1e-146 X-RAY
2004-04-20 VAL A:121 A:121 2.0 0.013 -94.9 154.6 2.0 0.013 0.0 HOH
2.781
O
O
VAL C:121 C:121 2.0 0.013 -96.8 157.0 NA NA NA
1p2o 1 P00766 80.82 1e-146 X-RAY
2004-04-20 VAL A:121 A:121 1.0 0.006 -99.6 152.3 1.0 0.006 0.0 HOH
4.746
N
O
VAL C:121 C:121 2.0 0.013 -99.1 151.1 NA NA NA
1p2q 1 P00766 80.82 1e-146 X-RAY
2004-04-20 VAL A:121 A:121 2.0 0.013 -95.3 154.5 2.0 0.013 0.0 HOH
2.735
O
O
VAL C:121 C:121 1.0 0.006 -96.3 156.5 NA NA NA
1t7c 1 P00766 80.82 1e-146 X-RAY
2005-03-08 VAL A:121 A:121 2.0 0.013 -95.1 154.4 2.0 0.013 0.0 HOH
2.699
O
O
VAL C:121 C:121 1.0 0.006 -96.3 157.6 NA NA NA
1t8l 1 P00766 80.82 1e-146 X-RAY
2005-03-08 VAL A:121 A:121 2.0 0.013 -95.2 154.4 2.0 0.013 0.0 HOH
2.708
O
O
VAL C:121 C:121 1.0 0.006 -94.8 155.6 NA NA NA
1t8m 1 P00766 80.82 1e-146 X-RAY
2005-03-08 VAL A:121 A:121 2.0 0.013 -95.3 156.1 2.0 0.013 0.0 HOH
2.750
O
O
VAL C:121 C:121 1.0 0.006 -97.3 157.4 NA NA NA
1t8n 1 P00766 80.82 1e-146 X-RAY
2005-03-08 VAL A:121 A:121 2.0 0.013 -94.6 154.0 2.0 0.013 0.0 HOH
2.739
O
O
VAL C:121 C:121 1.0 0.006 -96.0 155.2 NA NA NA
1t8o 1 P00766 80.82 1e-146 X-RAY
2005-03-08 VAL A:121 A:121 2.0 0.013 -95.0 155.0 2.0 0.013 0.0 HOH
2.703
O
O
VAL C:121 C:121 2.0 0.013 -98.1 155.3 NA NA NA
2cga 1 P00766 80.82 1e-146 X-RAY
1987-04-16 VAL A:121 A:121 2.0 0.013 -86.3 147.9 2.0 0.013 0.0 HOH
2.633
O
O
VAL B:121 B:121 2.0 0.013 -91.3 164.2 2.0 0.013 0.0 HOH
2.657
O
O
2y6t 1 P00766 80.82 1e-146 X-RAY
2011-04-20 VAL A:121 A:121 1.0 0.006 -85.6 152.7 1.0 0.006 0.0 HOH
7.151
N
O
VAL B:121 B:121 2.0 0.013 -88.4 161.5 2.0 0.013 0.0
VAL C:121 C:121 1.0 0.006 -97.9 148.8 NA NA NA
VAL D:121 D:121 2.0 0.013 -81.9 155.3 NA NA NA
3t62 1 P00766 80.82 1e-146 X-RAY
2012-08-01 VAL A:121 A:121 2.0 0.013 -87.5 153.1 2.0 0.013 0.0 HOH
2.754
O
O
VAL C:121 B:121 2.0 0.013 -81.6 153.1 NA NA NA
VAL E:121 C:121 2.0 0.013 -80.9 155.8 NA NA NA
4q2k 1 P00766 80.82 1e-146 X-RAY
2014-07-23 VAL A:121 A:121 3.0 0.019 -78.9 154.6 3.0 0.019 0.0 HOH
2.862
O
O
VAL B:121 B:121 2.0 0.013 -84.9 154.0 NA NA NA
VAL C:121 C:121 2.0 0.013 -86.5 155.2 NA NA NA
VAL D:121 D:121 2.0 0.013 -86.5 150.4 2.0 0.013 0.0 HOH
2.865
O
O
5j4q 1 P00766 80.82 1e-146 X-RAY
2017-04-12 VAL A:121 A:121 1.0 0.006 -84.2 148.7 1.0 0.006 0.0 HOH
4.737
N
O
5j4s 1 P00766 80.82 1e-146 X-RAY
2017-04-12 VAL A:121 A:121 2.0 0.013 -86.5 155.9 2.0 0.013 0.0 HOH
2.612
O
O
7kty 1 P00766 80.82 1e-146 X-RAY
2021-03-10 VAL A:121 A:121 3.0 0.019 -81.0 153.8 3.0 0.019 0.0 HOH
2.799
O
O
7ktz 1 P00766 80.82 1e-146 X-RAY
2021-03-10 VAL A:121 A:121 2.0 0.013 -78.4 153.6 2.0 0.013 0.0 HOH
2.750
O
O
7ku0 1 P00766 80.82 1e-146 X-RAY
2021-03-10 VAL A:121 A:121 2.0 0.013 -78.1 154.1 2.0 0.013 0.0 HOH
2.676
O
O
7ku1 1 P00766 80.82 1e-146 X-RAY
2021-03-10 VAL A:121 A:121 2.0 0.013 -82.0 151.9 2.0 0.013 0.0 HOH
8.051
O
O
7ku2 1 P00766 80.82 1e-146 X-RAY
2021-03-10 VAL A:121 A:121 3.0 0.019 -81.5 153.4 3.0 0.019 0.0 HOH
2.736
O
O
7ku3 1 P00766 80.82 1e-146 X-RAY
2021-03-10 VAL A:121 A:121 2.0 0.013 -79.8 155.1 2.0 0.013 0.0 HOH
2.639
O
O
1kdq 1 P07338 89.31 3e-84 X-RAY
2003-06-10 VAL A:106 A:121 40.0 0.258 -102.7 142.6 6.0 0.039 0.219 B:P07338:0.219
HOH
7.263
CG2
O
2jet 2 P07338 89.84 6e-83 X-RAY
2007-09-18 VAL B:103 B:121 43.0 0.277 -112.4 148.1 2.0 0.013 0.264 A:P07338:0.065
C:P07338:0.239
HOH
4.999
N
O
1ab9 2 P00766 83.21 3e-76 X-RAY
1997-08-20 VAL B:106 B:121 44.0 0.284 -92.1 153.1 3.0 0.019 0.265 C:P00766:0.245
A:P00766:0.032
HOH
2.739
O
O
1afq 2 P00766 83.21 3e-76 X-RAY
1997-09-17 VAL B:106 B:121 42.0 0.271 -91.8 152.6 0.0 0.0 0.271 A:P00766:0.013
C:P00766:0.232
0FG
HOH
4.628
2.649
O
O
O
O
1ca0 2 P00766 83.21 3e-76 X-RAY
1997-07-23 VAL B:106 B:121 42.0 0.271 -92.5 151.6 2.0 0.013 0.258 C:P00766:0.232
A:P00766:0.032
HOH
2.918
O
O
VAL F:106 G:121 43.0 0.277 -101.9 151.0 NA NA NA
1cbw 2 P00766 83.21 3e-76 X-RAY
1997-07-23 VAL B:106 B:121 45.0 0.29 -91.1 160.7 2.0 0.013 0.277 C:P00766:0.239
A:P00767:0.052
HOH
5.974
O
O
VAL F:106 G:121 42.0 0.271 -92.5 157.3 NA NA NA
1cho 2 P00766 83.21 3e-76 X-RAY
1988-07-16 VAL B:106 F:121 44.0 0.284 -97.5 154.4 2.0 0.013 0.271 C:P00766:0.245
A:P00766:0.039
HOH
4.446
O
O
1gct 2 P00766 83.21 3e-76 X-RAY
1991-10-15 VAL B:106 B:121 42.0 0.271 -89.4 153.6 3.0 0.019 0.252 A:P00766:0.032
C:P00766:0.232
HOH
2.458
O
O
1gg6 2 P00766 83.21 3e-76 X-RAY
2000-09-20 VAL B:106 B:121 43.0 0.277 -90.4 158.7 2.0 0.013 0.264 C:P00766:0.232
A:P00766:0.045
EDO
EDO
HOH
7.902
6.378
2.660
C
O
O
C1
C1
O
1ggd 2 P00766 83.21 3e-76 X-RAY
2000-09-20 VAL B:106 B:121 43.0 0.277 -92.8 156.4 3.0 0.019 0.258 C:P00766:0.239
A:P00766:0.032
HOH
2.772
O
O
1gha 2 P00766 83.21 3e-76 X-RAY
1994-06-22 VAL B:106 F:121 42.0 0.271 -92.8 154.4 2.0 0.013 0.258 C:P00766:0.232
A:P00766:0.039
HOH
2.834
O
O
1ghb 2 P00766 83.21 3e-76 X-RAY
1994-06-22 VAL B:106 F:121 48.0 0.31 -90.7 153.3 2.0 0.013 0.297 A:P00766:0.039
C:P00766:0.277
HEX
HOH
5.048
3.329
N
O
C1
O
1gmc 2 P00766 83.21 3e-76 X-RAY
1993-10-31 VAL B:106 F:121 42.0 0.271 -87.3 154.6 3.0 0.019 0.252 A:P00766:0.032
C:P00766:0.232
HOH
2.608
O
O
1gmd 2 P00766 83.21 3e-76 X-RAY
1993-10-31 VAL B:106 F:121 47.0 0.303 -90.7 156.2 2.0 0.013 0.29 A:P00766:0.039
C:P00766:0.265
HEX
HEX
HEX
HOH
6.387
9.371
7.543
5.398
CG2
N
N
N
C5
C6
C1
O
1gmh 2 P00766 83.21 3e-76 X-RAY
1994-09-30 VAL B:106 F:121 45.0 0.29 -92.8 157.5 2.0 0.013 0.277 A:P00766:0.039
C:P00766:0.258
HOH
2.962
O
O
1hja 2 P00766 83.21 3e-76 X-RAY
1998-01-14 VAL B:106 B:121 43.0 0.277 -101.4 155.1 2.0 0.013 0.264 C:P00766:0.226
A:P00766:0.045
HOH
2.744
O
O
1mtn 2 P00766 83.21 3e-76 X-RAY
1996-08-17 VAL B:106 B:121 46.0 0.297 -96.5 156.7 3.0 0.019 0.278 C:P00766:0.239
A:P00766:0.058
HOH
6.587
CG1
O
VAL F:106 F:121 51.0 0.329 -95.3 164.4 NA NA NA
1n8o 2 P00766 83.21 3e-76 X-RAY
2002-12-18 VAL B:106 B:121 44.0 0.284 -91.3 151.5 2.0 0.013 0.271 C:P00766:0.245
A:P00766:0.032
HOH
2.745
O
O
1vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 VAL B:106 B:121 44.0 0.284 -93.1 159.7 3.0 0.019 0.265 C:P00766:0.239
A:P00766:0.039
HOH
2.685
O
O
1yph 2 P00766 83.21 3e-76 X-RAY
2006-02-14 VAL B:106 C:121 41.0 0.265 -85.3 153.1 2.0 0.013 0.252 C:P00766:0.226
A:P00766:0.032
HOH
2.732
O
O
VAL E:106 D:121 42.0 0.271 -88.2 151.4 2.0 0.013 0.258 F:P00766:0.232
D:P00766:0.032
HOH
2.760
O
O
2cha 2 P00766 83.21 3e-76 X-RAY
1977-01-18 VAL B:106 B:121 43.0 0.277 -78.9 141.5 2.0 0.013 0.264 C:P00766:0.239
A:P00766:0.032
HOH
2.869
O
O
VAL E:106 F:121 41.0 0.265 -78.9 141.5 2.0 0.013 0.252 F:P00766:0.232
D:P00766:0.019
2gch 2 P00766 83.21 3e-76 X-RAY
1980-07-09 VAL B:106 F:121 45.0 0.29 -87.8 156.9 2.0 0.013 0.277 C:P00766:0.252
A:P00766:0.039
HOH
2.371
O
O
2gct 2 P00766 83.21 3e-76 X-RAY
1991-10-15 VAL B:106 B:121 43.0 0.277 -91.8 153.3 1.0 0.006 0.271 A:P00766:0.032
C:P00766:0.252
HOH
2.750
O
O
2gmt 2 P00766 83.21 3e-76 X-RAY
1994-11-01 VAL B:106 B:121 43.0 0.277 -83.1 152.7 3.0 0.019 0.258 C:P00766:0.232
A:P00766:0.039
HOH
2.281
O
O
2p8o 2 P00766 83.21 3e-76 X-RAY
2007-05-08 VAL B:106 B:121 41.0 0.265 -81.8 156.0 2.0 0.013 0.252 C:P00766:0.219
A:P00766:0.032
HOH
2.712
O
O
2vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 VAL B:106 B:121 42.0 0.271 -96.1 153.4 3.0 0.019 0.252 C:P00766:0.232
A:P00766:0.032
HOH
2.730
O
O
3bg4 2 P00766 83.21 3e-76 X-RAY
2008-07-29 VAL B:106 B:121 40.0 0.258 -100.4 156.6 2.0 0.013 0.245 C:P00766:0.219
A:P00766:0.039
HOH
2.896
O
O
3gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 VAL B:106 B:121 44.0 0.284 -98.4 159.7 2.0 0.013 0.271 C:P00766:0.245
A:P00766:0.039
HOH
2.249
O
O
3gct 2 P00766 83.21 3e-76 X-RAY
1991-10-15 VAL B:106 F:121 42.0 0.271 -94.3 156.7 3.0 0.019 0.252 C:P00766:0.232
A:P00766:0.039
HOH
2.649
O
O
3ru4 4 P00766 83.21 3e-76 X-RAY
2012-08-29 VAL D:106 D:121 40.0 0.258 -86.8 153.1 NA NA NA
3vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 VAL B:106 B:121 46.0 0.297 -93.8 155.0 4.0 0.026 0.271 A:P00766:0.039
C:P00766:0.252
HOH
2.787
O
O
4cha 2 P00766 83.21 3e-76 X-RAY
1985-04-01 VAL B:106 B:121 44.0 0.284 -88.6 157.3 2.0 0.013 0.271 C:P00766:0.245
A:P00766:0.039
HOH
2.677
O
O
VAL E:106 F:121 43.0 0.277 -89.1 155.6 2.0 0.013 0.264 F:P00766:0.232
D:P00766:0.039
HOH
2.731
O
O
4gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 VAL B:106 F:121 47.0 0.303 -93.1 169.9 2.0 0.013 0.29 C:P00766:0.265
A:P00766:0.045
HOH
2.385
O
O
4vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 VAL B:106 B:121 42.0 0.271 -95.7 153.6 4.0 0.026 0.245 C:P00766:0.226
A:P00766:0.032
HOH
2.849
O
O
5cha 2 P00766 83.21 3e-76 X-RAY
1985-04-01 VAL B:106 B:121 44.0 0.284 -87.2 158.9 3.0 0.019 0.265 C:P00766:0.252
A:P00766:0.026
HOH
2.961
O
O
VAL E:106 F:121 44.0 0.284 -91.7 158.2 2.0 0.013 0.271 F:P00766:0.245
D:P00766:0.039
HOH
3.112
O
O
5gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 VAL B:106 F:121 41.0 0.265 -103.9 158.9 3.0 0.019 0.246 A:P00766:0.039
C:P00766:0.219
HOH
2.848
O
O
5r42 2 P00766 83.21 3e-76 X-RAY
2021-09-01 VAL B:106 B:121 44.0 0.284 -86.2 153.3 3.0 0.019 0.265 C:P00766:0.239
A:P00766:0.032
HOH
2.742
O
O
5r43 2 P00766 83.21 3e-76 X-RAY
2021-09-01 VAL B:106 B:121 41.0 0.265 -85.4 153.1 2.0 0.013 0.252 C:P00766:0.226
A:P00766:0.032
MLA
HOH
6.195
2.719
N
O
O3B
O
5r44 2 P00766 83.21 3e-76 X-RAY
2021-09-01 VAL B:106 B:121 44.0 0.284 -86.6 153.4 2.0 0.013 0.271 A:P00766:0.032
C:P00766:0.245
HOH
2.750
O
O
5r45 2 P00766 83.21 3e-76 X-RAY
2021-09-01 VAL B:106 B:121 41.0 0.265 -83.8 152.0 2.0 0.013 0.252 A:P00766:0.026
C:P00766:0.226
MLI
HOH
6.305
2.749
N
O
O7
O
5r46 2 P00766 83.21 3e-76 X-RAY
2021-09-01 VAL B:106 B:121 44.0 0.284 -84.6 153.6 3.0 0.019 0.265 A:P00766:0.039
C:P00766:0.239
HOH
2.734
O
O
5r47 2 P00766 83.21 3e-76 X-RAY
2021-09-01 VAL B:106 B:121 40.0 0.258 -84.6 152.4 2.0 0.013 0.245 A:P00766:0.026
C:P00766:0.219
MLA
MLA
HOH
6.355
6.203
2.723
N
O
O
O1A
C2
O
5r48 2 P00766 83.21 3e-76 X-RAY
2021-09-01 VAL B:106 B:121 43.0 0.277 -85.2 153.4 3.0 0.019 0.258 C:P00766:0.232
A:P00766:0.032
HOH
2.738
O
O
5r49 2 P00766 83.21 3e-76 X-RAY
2021-09-01 VAL B:106 B:121 40.0 0.258 -84.4 152.0 2.0 0.013 0.245 C:P00766:0.219
A:P00766:0.026
MLI
HOH
6.298
2.731
N
O
O7
O
5r4a 2 P00766 83.21 3e-76 X-RAY
2021-09-01 VAL B:106 B:121 44.0 0.284 -84.4 153.3 3.0 0.019 0.265 A:P00766:0.032
C:P00766:0.239
HOH
2.729
O
O
5r4b 2 P00766 83.21 3e-76 X-RAY
2021-09-01 VAL B:106 B:121 40.0 0.258 -84.1 153.4 2.0 0.013 0.245 C:P00766:0.219
A:P00766:0.026
SO4
HOH
7.675
2.725
N
O
O4
O
5r4c 2 P00766 83.21 3e-76 X-RAY
2021-09-01 VAL B:106 B:121 44.0 0.284 -84.5 154.0 3.0 0.019 0.265 A:P00766:0.032
C:P00766:0.239
HOH
2.723
O
O
5r4d 2 P00766 83.21 3e-76 X-RAY
2021-09-01 VAL B:106 B:121 40.0 0.258 -84.3 153.6 2.0 0.013 0.245 C:P00766:0.219
A:P00766:0.026
HOH
2.712
O
O
6cha 2 P00766 83.21 3e-76 X-RAY
1987-04-16 VAL B:106 B:121 47.0 0.303 -90.5 162.4 3.0 0.019 0.284 A:P00766:0.052
C:P00766:0.252
HOH
2.723
O
O
VAL E:106 F:121 44.0 0.284 -84.4 161.2 2.0 0.013 0.271 F:P00766:0.239
D:P00766:0.039
HOH
3.974
O
O
6di8 2 P00766 83.21 3e-76 X-RAY
2019-01-23 VAL B:106 B:121 42.0 0.271 -82.7 155.6 2.0 0.013 0.258 A:P00766:0.039
C:P00766:0.232
HOH
2.552
O
O
VAL E:106 E:121 40.0 0.258 -82.2 154.7 NA NA NA
VAL H:106 H:121 44.0 0.284 -83.2 155.8 NA NA NA
VAL K:106 K:121 40.0 0.258 -80.5 154.9 NA NA NA
6gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 VAL B:106 F:121 44.0 0.284 -92.5 163.0 4.0 0.026 0.258 C:P00766:0.219
A:P00766:0.052
HOH
2.398
O
O
7gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 VAL B:106 F:121 42.0 0.271 -93.0 155.4 3.0 0.019 0.252 C:P00766:0.226
A:P00766:0.032
HOH
2.597
O
O
7jrx 2 P00766 83.21 3e-76 X-RAY
2021-07-21 VAL B:106 B:121 44.0 0.284 -87.7 151.0 2.0 0.013 0.271 C:P00766:0.245
A:P00766:0.039
HOH
2.652
O
O
VAL F:106 b:121 43.0 0.277 -83.1 151.9 NA NA NA
8gch 2 P00766 83.21 3e-76 X-RAY
1992-04-15 VAL B:106 F:121 40.0 0.258 -91.3 158.0 2.0 0.013 0.245 C:P00766:0.226
A:P00766:0.026
HOH
2.654
O
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q6gpi1-f1 1 Q6GPI1 100.0 0.0 VAL A:139 A:139 2.0 0.013 -80.8 150.9
af-p17538-f1 1 P17538 95.82 0.0 VAL A:139 A:139 2.0 0.013 -79.3 150.2