Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 75239336 . G A CCDS32489.1:NM_001025200.3:c.391Cgc>Tgc_NP_001020371.3:p.131R>C Homo sapiens chymotrypsinogen B2 (CTRB2), mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1acb 1 P00766 80.82 1e-146 X-RAY
1993-10-31 SER A:113 E:113 76.0 0.661 -97.2 113.6 76.0 0.661 0.0 HOH
6.924
C
O
1cgi 1 P00766 80.82 1e-146 X-RAY
1993-10-31 SER A:113 E:113 75.0 0.652 -84.7 95.3 75.0 0.652 0.0 HOH
8.602
C
O
1cgj 1 P00766 80.82 1e-146 X-RAY
1993-10-31 SER A:113 E:113 83.0 0.722 -105.7 101.0 83.0 0.722 0.0 HOH
8.175
OG
O
1chg 1 P00766 80.82 1e-146 X-RAY
1976-11-22 SER A:113 A:113 81.0 0.704 -97.5 89.9 81.0 0.704 0.0
1ex3 1 P00766 80.82 1e-146 X-RAY
2000-05-17 SER A:113 A:113 74.0 0.643 -79.5 115.8 74.0 0.643 0.0 HOH
8.206
O
O
1gcd 1 P00766 80.82 1e-146 X-RAY
1994-06-22 SER A:113 A:113 79.0 0.687 -98.2 104.2 79.0 0.687 0.0 SO4
HOH
6.896
3.057
O
O
O2
O
1gl0 1 P00766 80.82 1e-146 X-RAY
2001-11-28 SER A:113 E:113 80.0 0.696 -111.4 108.9 80.0 0.696 0.0 CD
HOH
9.318
8.221
C
O
CD
O
1gl1 1 P00766 80.82 1e-146 X-RAY
2001-11-28 SER A:113 A:113 79.0 0.687 -92.9 108.5 79.0 0.687 0.0 HOH
3.530
CA
O
SER B:113 B:113 81.0 0.704 -97.1 106.4 NA NA NA
SER C:113 C:113 83.0 0.722 -96.4 105.3 NA NA NA
1k2i 1 P00766 80.82 1e-146 X-RAY
2001-12-05 SER A:113 1:113 77.0 0.67 -104.9 105.9 77.0 0.67 0.0 HOH
6.890
C
O
1oxg 1 P00766 80.82 1e-146 X-RAY
2004-05-18 SER A:113 A:113 83.0 0.722 -92.2 118.3 83.0 0.722 0.0 SO4
HOH
7.880
3.044
O
OG
O4
O
1p2m 1 P00766 80.82 1e-146 X-RAY
2004-04-20 SER A:113 A:113 81.0 0.704 -95.6 103.5 81.0 0.704 0.0 HOH
3.652
CA
O
SER C:113 C:113 80.0 0.696 -96.4 102.8 NA NA NA
1p2n 1 P00766 80.82 1e-146 X-RAY
2004-04-20 SER A:113 A:113 83.0 0.722 -94.9 103.2 83.0 0.722 0.0 HOH
3.642
CA
O
SER C:113 C:113 79.0 0.687 -99.0 102.7 NA NA NA
1p2o 1 P00766 80.82 1e-146 X-RAY
2004-04-20 SER A:113 A:113 83.0 0.722 -94.1 95.4 83.0 0.722 0.0 HOH
8.377
O
O
SER C:113 C:113 81.0 0.704 -91.3 102.2 NA NA NA
1p2q 1 P00766 80.82 1e-146 X-RAY
2004-04-20 SER A:113 A:113 84.0 0.73 -91.4 104.3 84.0 0.73 0.0 HOH
3.539
OG
O
SER C:113 C:113 77.0 0.67 -99.8 103.3 NA NA NA
1t7c 1 P00766 80.82 1e-146 X-RAY
2005-03-08 SER A:113 A:113 84.0 0.73 -87.5 101.3 84.0 0.73 0.0 HOH
3.526
CA
O
SER C:113 C:113 77.0 0.67 -98.6 104.8 NA NA NA
1t8l 1 P00766 80.82 1e-146 X-RAY
2005-03-08 SER A:113 A:113 79.0 0.687 -93.5 101.0 79.0 0.687 0.0 HOH
5.364
O
O
SER C:113 C:113 76.0 0.661 -101.9 101.4 NA NA NA
1t8m 1 P00766 80.82 1e-146 X-RAY
2005-03-08 SER A:113 A:113 81.0 0.704 -91.6 102.0 81.0 0.704 0.0 HOH
3.556
CA
O
SER C:113 C:113 81.0 0.704 -94.3 103.6 NA NA NA
1t8n 1 P00766 80.82 1e-146 X-RAY
2005-03-08 SER A:113 A:113 81.0 0.704 -91.9 104.3 81.0 0.704 0.0 HOH
3.515
CA
O
SER C:113 C:113 78.0 0.678 -94.3 106.7 NA NA NA
1t8o 1 P00766 80.82 1e-146 X-RAY
2005-03-08 SER A:113 A:113 80.0 0.696 -94.8 102.1 80.0 0.696 0.0 HOH
3.256
OG
O
SER C:113 C:113 80.0 0.696 -96.8 102.6 NA NA NA
2cga 1 P00766 80.82 1e-146 X-RAY
1987-04-16 SER A:113 A:113 74.0 0.643 -105.6 98.0 49.0 0.426 0.217 B:P00766:0.217
HOH
3.536
CB
O
SER B:113 B:113 81.0 0.704 -104.0 92.7 81.0 0.704 0.0 HOH
3.329
O
O
2y6t 1 P00766 80.82 1e-146 X-RAY
2011-04-20 SER A:113 A:113 80.0 0.696 -96.4 103.4 80.0 0.696 0.0
SER B:113 B:113 78.0 0.678 -91.5 121.6 78.0 0.678 0.0
SER C:113 C:113 78.0 0.678 -89.7 112.2 NA NA NA
SER D:113 D:113 83.0 0.722 -86.7 101.9 NA NA NA
3t62 1 P00766 80.82 1e-146 X-RAY
2012-08-01 SER A:113 A:113 77.0 0.67 -99.8 115.4 77.0 0.67 0.0 HOH
2.879
OG
O
SER C:113 B:113 76.0 0.661 -99.9 112.5 NA NA NA
SER E:113 C:113 78.0 0.678 -95.8 117.9 NA NA NA
4q2k 1 P00766 80.82 1e-146 X-RAY
2014-07-23 SER A:113 A:113 78.0 0.678 -75.5 123.8 78.0 0.678 0.0 HOH
3.468
O
O
SER B:113 B:113 82.0 0.713 -103.8 110.6 NA NA NA
SER C:113 C:113 73.0 0.635 -89.8 123.0 NA NA NA
SER D:113 D:113 85.0 0.739 -90.5 120.8 85.0 0.739 0.0 HOH
3.838
N
O
5j4q 1 P00766 80.82 1e-146 X-RAY
2017-04-12 SER A:113 A:113 83.0 0.722 -90.9 110.1 83.0 0.722 0.0 HOH
3.658
CA
O
5j4s 1 P00766 80.82 1e-146 X-RAY
2017-04-12 SER A:113 A:113 77.0 0.67 -104.1 105.0 77.0 0.67 0.0 HOH
3.944
H
O
7kty 1 P00766 80.82 1e-146 X-RAY
2021-03-10 SER A:113 A:113 85.0 0.739 -103.4 108.2 85.0 0.739 0.0 HOH
4.740
O
O
7ktz 1 P00766 80.82 1e-146 X-RAY
2021-03-10 SER A:113 A:113 84.0 0.73 -98.7 106.2 84.0 0.73 0.0 HOH
2.794
OG
O
7ku0 1 P00766 80.82 1e-146 X-RAY
2021-03-10 SER A:113 A:113 82.0 0.713 -98.2 106.1 82.0 0.713 0.0 HOH
2.685
OG
O
7ku1 1 P00766 80.82 1e-146 X-RAY
2021-03-10 SER A:113 A:113 85.0 0.739 -92.1 107.5 85.0 0.739 0.0 HOH
5.313
O
O
7ku2 1 P00766 80.82 1e-146 X-RAY
2021-03-10 SER A:113 A:113 81.0 0.704 -95.1 111.2 81.0 0.704 0.0 HOH
4.491
O
O
7ku3 1 P00766 80.82 1e-146 X-RAY
2021-03-10 SER A:113 A:113 82.0 0.713 -92.3 106.7 82.0 0.713 0.0 HOH
2.989
OG
O
1kdq 1 P07338 89.31 3e-84 X-RAY
2003-06-10 GLN A:98 A:113 148.0 0.822 -91.1 105.2 148.0 0.822 0.0 HOH
7.811
O
O
2jet 2 P07338 89.84 6e-83 X-RAY
2007-09-18 GLN B:95 B:113 147.0 0.817 -76.0 100.9 147.0 0.817 0.0 HOH
3.247
CB
O
1ab9 2 P00766 83.21 3e-76 X-RAY
1997-08-20 SER B:98 B:113 79.0 0.687 -103.5 110.9 79.0 0.687 0.0 HOH
3.812
C
O
1afq 2 P00766 83.21 3e-76 X-RAY
1997-09-17 SER B:98 B:113 79.0 0.687 -103.6 110.5 79.0 0.687 0.0 HOH
3.883
CA
O
1ca0 2 P00766 83.21 3e-76 X-RAY
1997-07-23 SER B:98 B:113 78.0 0.678 -106.7 112.0 78.0 0.678 0.0 HOH
4.895
O
O
SER F:98 G:113 84.0 0.73 -82.1 116.6 NA NA NA
1cbw 2 P00766 83.21 3e-76 X-RAY
1997-07-23 SER B:98 B:113 84.0 0.73 -92.0 111.0 84.0 0.73 0.0 HOH
7.769
O
O
SER F:98 G:113 85.0 0.739 -88.6 121.8 NA NA NA
1cho 2 P00766 83.21 3e-76 X-RAY
1988-07-16 SER B:98 F:113 84.0 0.73 -95.6 104.6 84.0 0.73 0.0 HOH
2.906
OG
O
1gct 2 P00766 83.21 3e-76 X-RAY
1991-10-15 SER B:98 B:113 79.0 0.687 -107.7 109.2 79.0 0.687 0.0 HOH
4.382
CA
O
1gg6 2 P00766 83.21 3e-76 X-RAY
2000-09-20 SER B:98 B:113 80.0 0.696 -98.8 105.8 80.0 0.696 0.0 HOH
2.989
OG
O
1ggd 2 P00766 83.21 3e-76 X-RAY
2000-09-20 SER B:98 B:113 77.0 0.67 -98.1 108.3 77.0 0.67 0.0 HOH
4.049
C
O
1gha 2 P00766 83.21 3e-76 X-RAY
1994-06-22 SER B:98 F:113 77.0 0.67 -112.8 107.1 77.0 0.67 0.0 HOH
3.125
OG
O
1ghb 2 P00766 83.21 3e-76 X-RAY
1994-06-22 SER B:98 F:113 81.0 0.704 -95.7 119.4 81.0 0.704 0.0 HOH
3.736
OG
O
1gmc 2 P00766 83.21 3e-76 X-RAY
1993-10-31 SER B:98 F:113 75.0 0.652 -107.2 112.0 75.0 0.652 0.0 HOH
3.603
OG
O
1gmd 2 P00766 83.21 3e-76 X-RAY
1993-10-31 SER B:98 F:113 80.0 0.696 -98.4 123.1 80.0 0.696 0.0 HEX
HEX
HOH
7.898
8.794
3.686
O
C
OG
C6
C5
O
1gmh 2 P00766 83.21 3e-76 X-RAY
1994-09-30 SER B:98 F:113 59.0 NA -105.7 115.4 59.0 NA NA HOH
5.557
O
O
1hja 2 P00766 83.21 3e-76 X-RAY
1998-01-14 SER B:98 B:113 79.0 0.687 -98.7 117.5 79.0 0.687 0.0 HOH
3.123
OG
O
1mtn 2 P00766 83.21 3e-76 X-RAY
1996-08-17 SER B:98 B:113 85.0 0.739 -83.2 102.2 85.0 0.739 0.0 HOH
8.140
O
O
SER F:98 F:113 83.0 0.722 -105.3 103.7 NA NA NA
1n8o 2 P00766 83.21 3e-76 X-RAY
2002-12-18 SER B:98 B:113 79.0 0.687 -91.4 117.7 79.0 0.687 0.0 HOH
3.235
OG
O
1vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 SER B:98 B:113 80.0 0.696 -100.6 113.2 80.0 0.696 0.0 HOH
4.022
CA
O
1yph 2 P00766 83.21 3e-76 X-RAY
2006-02-14 SER B:98 C:113 77.0 0.67 -94.9 108.4 77.0 0.67 0.0 HOH
4.603
O
O
SER E:98 D:113 82.0 0.713 -98.1 111.3 82.0 0.713 0.0 HOH
3.687
CA
O
2cha 2 P00766 83.21 3e-76 X-RAY
1977-01-18 SER B:98 B:113 75.0 0.652 -93.0 127.2 75.0 0.652 0.0 HOH
3.762
CB
O
SER E:98 F:113 76.0 0.661 -93.0 127.2 76.0 0.661 0.0
2gch 2 P00766 83.21 3e-76 X-RAY
1980-07-09 SER B:98 F:113 79.0 0.687 -99.5 105.6 79.0 0.687 0.0 HOH
3.038
OG
O
2gct 2 P00766 83.21 3e-76 X-RAY
1991-10-15 SER B:98 B:113 75.0 0.652 -101.0 113.2 75.0 0.652 0.0 HOH
4.461
O
O
2gmt 2 P00766 83.21 3e-76 X-RAY
1994-11-01 SER B:98 B:113 83.0 0.722 -90.7 112.5 83.0 0.722 0.0 HOH
2.629
CA
O
2p8o 2 P00766 83.21 3e-76 X-RAY
2007-05-08 SER B:98 B:113 81.0 0.704 -98.9 110.5 81.0 0.704 0.0 HOH
3.761
OG
O
2vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 SER B:98 B:113 81.0 0.704 -102.7 111.4 81.0 0.704 0.0 HOH
3.795
C
O
3bg4 2 P00766 83.21 3e-76 X-RAY
2008-07-29 SER B:98 B:113 81.0 0.704 -104.5 106.2 81.0 0.704 0.0 HOH
3.787
N
O
3gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 SER B:98 B:113 81.0 0.704 -98.9 116.5 81.0 0.704 0.0 HOH
4.193
C
O
3gct 2 P00766 83.21 3e-76 X-RAY
1991-10-15 SER B:98 F:113 82.0 0.713 -104.5 114.2 82.0 0.713 0.0 HOH
4.475
O
O
3ru4 4 P00766 83.21 3e-76 X-RAY
2012-08-29 SER D:98 D:113 78.0 0.678 -95.5 113.3 NA NA NA
3vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 SER B:98 B:113 80.0 0.696 -103.3 111.8 80.0 0.696 0.0 SO4
HOH
6.890
3.929
OG
C
O2
O
4cha 2 P00766 83.21 3e-76 X-RAY
1985-04-01 SER B:98 B:113 73.0 0.635 -101.3 118.0 73.0 0.635 0.0 HOH
7.698
O
O
SER E:98 F:113 82.0 0.713 -89.7 116.8 82.0 0.713 0.0 HOH
8.022
O
O
4gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 SER B:98 F:113 82.0 0.713 -92.9 106.0 82.0 0.713 0.0 HOH
4.417
C
O
4vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 SER B:98 B:113 81.0 0.704 -98.9 111.5 81.0 0.704 0.0 HOH
3.874
C
O
5cha 2 P00766 83.21 3e-76 X-RAY
1985-04-01 SER B:98 B:113 78.0 0.678 -116.3 89.4 78.0 0.678 0.0 HOH
2.951
O
O
SER E:98 F:113 79.0 0.687 -106.1 109.6 79.0 0.687 0.0 HOH
3.885
CA
O
5gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 SER B:98 F:113 80.0 0.696 -110.9 109.1 80.0 0.696 0.0 HOH
4.231
C
O
5r42 2 P00766 83.21 3e-76 X-RAY
2021-09-01 SER B:98 B:113 79.0 0.687 -99.3 111.4 79.0 0.687 0.0 HOH
5.228
O
O
5r43 2 P00766 83.21 3e-76 X-RAY
2021-09-01 SER B:98 B:113 78.0 0.678 -97.1 111.2 78.0 0.678 0.0 MLA
HOH
8.986
4.485
C
O
O1A
O
5r44 2 P00766 83.21 3e-76 X-RAY
2021-09-01 SER B:98 B:113 79.0 0.687 -99.4 110.6 79.0 0.687 0.0 HOH
5.121
O
O
5r45 2 P00766 83.21 3e-76 X-RAY
2021-09-01 SER B:98 B:113 78.0 0.678 -102.0 105.8 78.0 0.678 0.0 MLI
HOH
9.061
4.842
C
O
O9
O
5r46 2 P00766 83.21 3e-76 X-RAY
2021-09-01 SER B:98 B:113 79.0 0.687 -99.0 112.1 79.0 0.687 0.0 HOH
5.269
O
O
5r47 2 P00766 83.21 3e-76 X-RAY
2021-09-01 SER B:98 B:113 80.0 0.696 -101.8 109.0 80.0 0.696 0.0 MLA
HOH
8.937
4.455
C
O
O3B
O
5r48 2 P00766 83.21 3e-76 X-RAY
2021-09-01 SER B:98 B:113 78.0 0.678 -98.2 111.9 78.0 0.678 0.0 HOH
5.236
O
O
5r49 2 P00766 83.21 3e-76 X-RAY
2021-09-01 SER B:98 B:113 79.0 0.687 -100.1 109.3 79.0 0.687 0.0 MLI
HOH
8.991
3.211
C
O
O9
O
5r4a 2 P00766 83.21 3e-76 X-RAY
2021-09-01 SER B:98 B:113 77.0 0.67 -97.7 111.5 77.0 0.67 0.0 HOH
5.309
O
O
5r4b 2 P00766 83.21 3e-76 X-RAY
2021-09-01 SER B:98 B:113 79.0 0.687 -97.5 115.2 79.0 0.687 0.0 HOH
3.339
OG
O
5r4c 2 P00766 83.21 3e-76 X-RAY
2021-09-01 SER B:98 B:113 79.0 0.687 -97.9 110.7 79.0 0.687 0.0 HOH
5.290
O
O
5r4d 2 P00766 83.21 3e-76 X-RAY
2021-09-01 SER B:98 B:113 78.0 0.678 -96.5 110.3 78.0 0.678 0.0 HOH
4.587
O
O
6cha 2 P00766 83.21 3e-76 X-RAY
1987-04-16 SER B:98 B:113 71.0 0.617 -109.4 99.2 71.0 0.617 0.0 HOH
8.948
O
O
SER E:98 F:113 76.0 0.661 -114.0 106.3 76.0 0.661 0.0 HOH
4.086
OG
O
6di8 2 P00766 83.21 3e-76 X-RAY
2019-01-23 SER B:98 B:113 80.0 0.696 -99.3 106.2 80.0 0.696 0.0 HOH
2.968
OG
O
SER E:98 E:113 80.0 0.696 -97.4 105.8 NA NA NA
SER H:98 H:113 80.0 0.696 -99.0 106.7 NA NA NA
SER K:98 K:113 78.0 0.678 -97.6 104.9 NA NA NA
6gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 SER B:98 F:113 83.0 0.722 -87.7 103.7 83.0 0.722 0.0 HOH
2.861
OG
O
7gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 SER B:98 F:113 80.0 0.696 -96.3 122.5 80.0 0.696 0.0 HOH
3.411
CB
O
7jrx 2 P00766 83.21 3e-76 X-RAY
2021-07-21 SER B:98 B:113 80.0 0.696 -93.0 105.0 80.0 0.696 0.0 HOH
2.850
OG
O
SER F:98 b:113 81.0 0.704 -89.0 106.0 NA NA NA
8gch 2 P00766 83.21 3e-76 X-RAY
1992-04-15 SER B:98 F:113 57.0 NA -98.9 110.0 57.0 NA NA SO4
HOH
7.020
3.183
O
O
O2
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q6gpi1-f1 1 Q6GPI1 100.0 0.0 ARG A:131 A:131 206.0 0.916 -86.9 103.2
af-p17538-f1 1 P17538 95.82 0.0 ARG A:131 A:131 203.0 0.902 -85.8 105.6