Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 75239708 . C A CCDS32489.1:NM_001025200.3:c.247Gtg>Ttg_NP_001020371.3:p.83V>L Homo sapiens chymotrypsinogen B2 (CTRB2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1acb 1 P00766 80.82 1e-146 X-RAY
 1993-10-31 VAL A:65 E:65 20.0 0.129 E -121.6 145.8 20.0 0.129 0.0 HOH
 3.296
 CG1
 O
1cgi 1 P00766 80.82 1e-146 X-RAY
 1993-10-31 VAL A:65 E:65 18.0 0.116 E -120.0 139.3 18.0 0.116 0.0 HOH
 6.736
 CG1
 O
1cgj 1 P00766 80.82 1e-146 X-RAY
 1993-10-31 VAL A:65 E:65 23.0 0.148 E -113.5 142.3 23.0 0.148 0.0 HOH
 6.859
 CG1
 O
1chg 1 P00766 80.82 1e-146 X-RAY
 1976-11-22 VAL A:65 A:65 23.0 0.148 E -120.2 144.2 23.0 0.148 0.0
1ex3 1 P00766 80.82 1e-146 X-RAY
 2000-05-17 VAL A:65 A:65 20.0 0.129 E -143.0 145.7 20.0 0.129 0.0 HOH
 7.462
 N
 O
1gcd 1 P00766 80.82 1e-146 X-RAY
 1994-06-22 VAL A:65 A:65 43.0 0.277 E -125.5 148.3 43.0 0.277 0.0 HOH
 3.839
 CG2
 O
1gl0 1 P00766 80.82 1e-146 X-RAY
 2001-11-28 VAL A:65 E:65 30.0 0.194 E -127.9 143.6 30.0 0.194 0.0 HOH
 3.622
 CG1
 O
1gl1 1 P00766 80.82 1e-146 X-RAY
 2001-11-28 VAL A:65 A:65 38.0 0.245 E -126.4 144.5 38.0 0.245 0.0 HOH
 4.643
 N
 O
VAL B:65 B:65 42.0 0.271 E -122.6 143.3 NA NA NA
VAL C:65 C:65 30.0 0.194 E -126.1 146.5 NA NA NA
1k2i 1 P00766 80.82 1e-146 X-RAY
 2001-12-05 VAL A:65 1:65 38.0 0.245 E -124.5 142.7 38.0 0.245 0.0 HOH
 4.045
 CG2
 O
1oxg 1 P00766 80.82 1e-146 X-RAY
 2004-05-18 VAL A:65 A:65 26.0 0.168 E -130.0 151.7 26.0 0.168 0.0 SO4
HOH
 9.991
3.214
 N
CG1
 O2
O
1p2m 1 P00766 80.82 1e-146 X-RAY
 2004-04-20 VAL A:65 A:65 32.0 0.206 E -130.7 154.0 32.0 0.206 0.0 HOH
 3.419
 CG2
 O
VAL C:65 C:65 13.0 0.084 E -130.5 152.8 NA NA NA
1p2n 1 P00766 80.82 1e-146 X-RAY
 2004-04-20 VAL A:65 A:65 34.0 0.219 E -128.5 155.7 34.0 0.219 0.0 HOH
 3.319
 CG2
 O
VAL C:65 C:65 33.0 0.213 E -131.7 153.4 NA NA NA
1p2o 1 P00766 80.82 1e-146 X-RAY
 2004-04-20 VAL A:65 A:65 31.0 0.2 E -134.7 151.7 31.0 0.2 0.0 HOH
 4.094
 CG2
 O
VAL C:65 C:65 11.0 0.071 E -131.9 153.1 NA NA NA
1p2q 1 P00766 80.82 1e-146 X-RAY
 2004-04-20 VAL A:65 A:65 32.0 0.206 E -128.4 149.9 32.0 0.206 0.0 TRS
HOH
 7.253
5.884
 N
N
 O3
O
VAL C:65 C:65 19.0 0.123 E -129.9 151.7 NA NA NA
1t7c 1 P00766 80.82 1e-146 X-RAY
 2005-03-08 VAL A:65 A:65 31.0 0.2 E -129.2 152.3 31.0 0.2 0.0 HOH
 3.322
 CG2
 O
VAL C:65 C:65 30.0 0.194 E -130.1 153.1 NA NA NA
1t8l 1 P00766 80.82 1e-146 X-RAY
 2005-03-08 VAL A:65 A:65 32.0 0.206 E -129.6 153.0 32.0 0.206 0.0 HOH
 3.332
 CG2
 O
VAL C:65 C:65 30.0 0.194 E -129.0 153.5 NA NA NA
1t8m 1 P00766 80.82 1e-146 X-RAY
 2005-03-08 VAL A:65 A:65 30.0 0.194 E -133.4 151.4 30.0 0.194 0.0 HOH
 3.328
 CG2
 O
VAL C:65 C:65 30.0 0.194 E -131.0 153.1 NA NA NA
1t8n 1 P00766 80.82 1e-146 X-RAY
 2005-03-08 VAL A:65 A:65 30.0 0.194 E -130.5 152.4 30.0 0.194 0.0 HOH
 3.338
 CG2
 O
VAL C:65 C:65 29.0 0.187 E -130.1 154.3 NA NA NA
1t8o 1 P00766 80.82 1e-146 X-RAY
 2005-03-08 VAL A:65 A:65 31.0 0.2 E -131.6 154.2 31.0 0.2 0.0 HOH
 3.401
 CG2
 O
VAL C:65 C:65 33.0 0.213 E -130.8 154.1 NA NA NA
2cga 1 P00766 80.82 1e-146 X-RAY
 1987-04-16 VAL A:65 A:65 29.0 0.187 E -114.3 150.9 29.0 0.187 0.0 HOH
 4.069
 CG1
 O
VAL B:65 B:65 27.0 0.174 E -131.2 146.5 27.0 0.174 0.0 HOH
 4.832
 N
 O
2y6t 1 P00766 80.82 1e-146 X-RAY
 2011-04-20 VAL A:65 A:65 33.0 0.213 E -126.4 138.8 33.0 0.213 0.0
VAL B:65 B:65 28.0 0.181 E -125.1 132.8 28.0 0.181 0.0
VAL C:65 C:65 30.0 0.194 E -122.1 141.4 NA NA NA
VAL D:65 D:65 32.0 0.206 E -130.8 133.0 NA NA NA
3t62 1 P00766 80.82 1e-146 X-RAY
 2012-08-01 VAL A:65 A:65 21.0 0.135 E -130.7 154.9 21.0 0.135 0.0 HOH
 3.563
 CG1
 O
VAL C:65 B:65 13.0 0.084 E -125.6 150.2 NA NA NA
VAL E:65 C:65 21.0 0.135 E -134.8 151.4 NA NA NA
4q2k 1 P00766 80.82 1e-146 X-RAY
 2014-07-23 VAL A:65 A:65 38.0 0.245 E -139.7 138.4 38.0 0.245 0.0 HOH
 3.241
 CB
 O
VAL B:65 B:65 23.0 0.148 E -125.1 134.1 NA NA NA
VAL C:65 C:65 19.0 0.123 E -138.3 138.0 NA NA NA
VAL D:65 D:65 32.0 0.206 E -128.1 136.8 32.0 0.206 0.0 HOH
 4.120
 CG1
 O
5j4q 1 P00766 80.82 1e-146 X-RAY
 2017-04-12 VAL A:65 A:65 21.0 0.135 E -123.7 139.3 21.0 0.135 0.0 HOH
 4.158
 CG2
 O
5j4s 1 P00766 80.82 1e-146 X-RAY
 2017-04-12 VAL A:65 A:65 22.0 0.142 E -123.6 139.5 22.0 0.142 0.0 HOH
 2.862
 HG11
 O
7kty 1 P00766 80.82 1e-146 X-RAY
 2021-03-10 VAL A:65 A:65 36.0 0.232 E -135.2 154.8 36.0 0.232 0.0 SO4
HOH
 9.852
3.662
 N
CG2
 O3
O
7ktz 1 P00766 80.82 1e-146 X-RAY
 2021-03-10 VAL A:65 A:65 9.0 0.058 E -127.3 139.8 9.0 0.058 0.0 SO4
HOH
 9.641
2.717
 N
CG2
 O3
O
7ku0 1 P00766 80.82 1e-146 X-RAY
 2021-03-10 VAL A:65 A:65 32.0 0.206 E -133.6 137.7 32.0 0.206 0.0 SO4
HOH
 9.543
3.724
 N
CG2
 O3
O
7ku1 1 P00766 80.82 1e-146 X-RAY
 2021-03-10 VAL A:65 A:65 34.0 0.219 E -135.8 137.1 34.0 0.219 0.0
7ku2 1 P00766 80.82 1e-146 X-RAY
 2021-03-10 VAL A:65 A:65 36.0 0.232 E -124.6 146.3 36.0 0.232 0.0 HOH
 4.220
 CG1
 O
7ku3 1 P00766 80.82 1e-146 X-RAY
 2021-03-10 VAL A:65 A:65 31.0 0.2 E -130.2 139.9 31.0 0.2 0.0 SO4
HOH
 9.685
3.664
 N
CG2
 O3
O
1kdq 1 P07338 89.31 3e-84 X-RAY
 2003-06-10 VAL A:50 A:65 24.0 0.155 E -108.3 163.5 24.0 0.155 0.0
2jet 2 P07338 89.84 6e-83 X-RAY
 2007-09-18 VAL B:47 B:65 30.0 0.194 E -124.0 151.1 30.0 0.194 0.0 HOH
 3.216
 CG2
 O
1ab9 2 P00766 83.21 3e-76 X-RAY
 1997-08-20 VAL B:50 B:65 38.0 0.245 E -121.8 141.8 38.0 0.245 0.0 HOH
 3.879
 CG2
 O
1afq 2 P00766 83.21 3e-76 X-RAY
 1997-09-17 VAL B:50 B:65 39.0 0.252 E -124.4 141.4 39.0 0.252 0.0 HOH
 4.618
 CA
 O
1ca0 2 P00766 83.21 3e-76 X-RAY
 1997-07-23 VAL B:50 B:65 36.0 0.232 E -122.4 135.6 36.0 0.232 0.0 HOH
 3.628
 CB
 O
VAL F:50 G:65 22.0 0.142 E -129.3 149.5 NA NA NA
1cbw 2 P00766 83.21 3e-76 X-RAY
 1997-07-23 VAL B:50 B:65 17.0 0.11 E -123.4 139.6 17.0 0.11 0.0 HOH
 3.185
 CB
 O
VAL F:50 G:65 15.0 0.097 E -137.1 134.6 NA NA NA
1cho 2 P00766 83.21 3e-76 X-RAY
 1988-07-16 VAL B:50 F:65 18.0 0.116 E -128.4 149.4 18.0 0.116 0.0 HOH
 3.601
 CG2
 O
1gct 2 P00766 83.21 3e-76 X-RAY
 1991-10-15 VAL B:50 B:65 31.0 0.2 E -123.0 145.8 31.0 0.2 0.0 HOH
 2.855
 CG1
 O
1gg6 2 P00766 83.21 3e-76 X-RAY
 2000-09-20 VAL B:50 B:65 30.0 0.194 E -129.9 152.1 30.0 0.194 0.0 HOH
 5.751
 N
 O
1ggd 2 P00766 83.21 3e-76 X-RAY
 2000-09-20 VAL B:50 B:65 40.0 0.258 E -125.7 141.3 40.0 0.258 0.0 HOH
 3.925
 CG2
 O
1gha 2 P00766 83.21 3e-76 X-RAY
 1994-06-22 VAL B:50 F:65 29.0 0.187 E -140.9 145.9 29.0 0.187 0.0 HOH
 3.217
 CG1
 O
1ghb 2 P00766 83.21 3e-76 X-RAY
 1994-06-22 VAL B:50 F:65 34.0 0.219 E -127.2 149.2 34.0 0.219 0.0 HOH
 3.692
 CG2
 O
1gmc 2 P00766 83.21 3e-76 X-RAY
 1993-10-31 VAL B:50 F:65 38.0 0.245 E -120.0 146.4 38.0 0.245 0.0 HOH
 4.398
 CB
 O
1gmd 2 P00766 83.21 3e-76 X-RAY
 1993-10-31 VAL B:50 F:65 38.0 0.245 E -125.2 144.5 38.0 0.245 0.0 HEX
HOH
 8.678
4.182
 O
CB
 C1
O
1gmh 2 P00766 83.21 3e-76 X-RAY
 1994-09-30 VAL B:50 F:65 33.0 0.213 E -120.6 147.3 33.0 0.213 0.0 HOH
 3.515
 CG1
 O
1hja 2 P00766 83.21 3e-76 X-RAY
 1998-01-14 VAL B:50 B:65 18.0 0.116 E -128.5 147.4 18.0 0.116 0.0 HOH
 6.235
 N
 O
1mtn 2 P00766 83.21 3e-76 X-RAY
 1996-08-17 VAL B:50 B:65 31.0 0.2 E -129.3 145.0 31.0 0.2 0.0 HOH
 4.790
 CA
 O
VAL F:50 F:65 31.0 0.2 E -136.2 141.7 NA NA NA
1n8o 2 P00766 83.21 3e-76 X-RAY
 2002-12-18 VAL B:50 B:65 13.0 0.084 E -128.9 141.3 13.0 0.084 0.0 HOH
 4.045
 CG2
 O
1vgc 2 P00766 83.21 3e-76 X-RAY
 1997-11-12 VAL B:50 B:65 41.0 0.265 E -119.2 142.2 41.0 0.265 0.0 HOH
 3.807
 CG2
 O
1yph 2 P00766 83.21 3e-76 X-RAY
 2006-02-14 VAL B:50 C:65 36.0 0.232 E -127.5 137.8 36.0 0.232 0.0 HOH
 3.870
 CG2
 O
VAL E:50 D:65 37.0 0.239 E -124.6 139.0 37.0 0.239 0.0 HOH
 3.569
 CB
 O
2cha 2 P00766 83.21 3e-76 X-RAY
 1977-01-18 VAL B:50 B:65 12.0 0.077 E -117.7 153.1 12.0 0.077 0.0 HOH
 4.062
 CG2
 O
VAL E:50 F:65 12.0 0.077 E -117.7 153.1 12.0 0.077 0.0
2gch 2 P00766 83.21 3e-76 X-RAY
 1980-07-09 VAL B:50 F:65 35.0 0.226 E -132.1 146.8 35.0 0.226 0.0 HOH
 2.824
 CG1
 O
2gct 2 P00766 83.21 3e-76 X-RAY
 1991-10-15 VAL B:50 B:65 31.0 0.2 E -125.4 141.9 31.0 0.2 0.0 SO4
HOH
 7.522
3.965
 CG2
CG1
 O2
O
2gmt 2 P00766 83.21 3e-76 X-RAY
 1994-11-01 VAL B:50 B:65 35.0 0.226 E -135.0 138.6 35.0 0.226 0.0 HOH
 2.891
 CG1
 O
2p8o 2 P00766 83.21 3e-76 X-RAY
 2007-05-08 VAL B:50 B:65 39.0 0.252 E -127.4 137.2 39.0 0.252 0.0 HOH
 2.793
 CG2
 O
2vgc 2 P00766 83.21 3e-76 X-RAY
 1997-11-12 VAL B:50 B:65 38.0 0.245 E -117.3 144.7 38.0 0.245 0.0 HOH
 9.124
 O
 O
3bg4 2 P00766 83.21 3e-76 X-RAY
 2008-07-29 VAL B:50 B:65 20.0 0.129 E -119.0 146.7 20.0 0.129 0.0 HOH
 4.488
 CG2
 O
3gch 2 P00766 83.21 3e-76 X-RAY
 1990-10-15 VAL B:50 B:65 37.0 0.239 E -120.3 137.4 37.0 0.239 0.0 HOH
 3.407
 CG1
 O
3gct 2 P00766 83.21 3e-76 X-RAY
 1991-10-15 VAL B:50 F:65 30.0 0.194 E -121.1 137.9 30.0 0.194 0.0 HOH
 3.702
 CG2
 O
3ru4 4 P00766 83.21 3e-76 X-RAY
 2012-08-29 VAL D:50 D:65 29.0 0.187 E -130.5 148.8 NA NA NA
3vgc 2 P00766 83.21 3e-76 X-RAY
 1997-11-12 VAL B:50 B:65 31.0 0.2 E -126.0 146.0 31.0 0.2 0.0 HOH
 3.162
 CG1
 O
4cha 2 P00766 83.21 3e-76 X-RAY
 1985-04-01 VAL B:50 B:65 37.0 0.239 E -121.8 148.9 37.0 0.239 0.0 HOH
 4.036
 CG2
 O
VAL E:50 F:65 13.0 0.084 E -126.6 144.2 13.0 0.084 0.0 HOH
 4.650
 N
 O
4gch 2 P00766 83.21 3e-76 X-RAY
 1990-10-15 VAL B:50 F:65 31.0 0.2 E -140.8 148.9 31.0 0.2 0.0 HOH
 2.546
 CG2
 O
4vgc 2 P00766 83.21 3e-76 X-RAY
 1997-11-12 VAL B:50 B:65 30.0 0.194 E -118.9 142.0 30.0 0.194 0.0 HOH
 9.087
 O
 O
5cha 2 P00766 83.21 3e-76 X-RAY
 1985-04-01 VAL B:50 B:65 22.0 0.142 E -124.8 146.3 22.0 0.142 0.0 HOH
 3.041
 CG1
 O
VAL E:50 F:65 10.0 0.065 E -123.6 137.5 10.0 0.065 0.0 HOH
 4.145
 CG2
 O
5gch 2 P00766 83.21 3e-76 X-RAY
 1990-10-15 VAL B:50 F:65 36.0 0.232 E -121.8 139.4 36.0 0.232 0.0 HOH
 3.071
 CG1
 O
5r42 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 VAL B:50 B:65 31.0 0.2 E -131.5 145.0 31.0 0.2 0.0 HOH
 5.969
 N
 O
5r43 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 VAL B:50 B:65 41.0 0.265 E -132.4 147.2 41.0 0.265 0.0 HOH
 6.095
 N
 O
5r44 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 VAL B:50 B:65 37.0 0.239 E -127.4 140.7 37.0 0.239 0.0 HOH
 3.761
 CG2
 O
5r45 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 VAL B:50 B:65 26.0 0.168 E -133.3 144.8 26.0 0.168 0.0 HOH
 6.276
 N
 O
5r46 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 VAL B:50 B:65 31.0 0.2 E -132.6 146.7 31.0 0.2 0.0 HOH
 5.920
 N
 O
5r47 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 VAL B:50 B:65 22.0 0.142 E -131.8 147.4 22.0 0.142 0.0 HOH
 6.419
 N
 O
5r48 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 VAL B:50 B:65 42.0 0.271 E -132.7 146.5 42.0 0.271 0.0 HOH
 5.887
 N
 O
5r49 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 VAL B:50 B:65 33.0 0.213 E -132.9 146.6 33.0 0.213 0.0 HOH
 6.450
 N
 O
5r4a 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 VAL B:50 B:65 38.0 0.245 E -127.4 140.3 38.0 0.245 0.0 HOH
 3.793
 CG2
 O
5r4b 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 VAL B:50 B:65 36.0 0.232 E -126.0 138.7 36.0 0.232 0.0 HOH
 5.752
 N
 O
5r4c 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 VAL B:50 B:65 30.0 0.194 E -132.0 146.4 30.0 0.194 0.0 HOH
 5.862
 N
 O
5r4d 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 VAL B:50 B:65 34.0 0.219 E -122.8 143.4 34.0 0.219 0.0 HOH
 5.610
 N
 O
6cha 2 P00766 83.21 3e-76 X-RAY
 1987-04-16 VAL B:50 B:65 30.0 0.194 E -128.5 147.3 30.0 0.194 0.0 HOH
 5.182
 CA
 O
VAL E:50 F:65 17.0 0.11 E -130.0 147.6 17.0 0.11 0.0 HOH
 2.788
 CG2
 O
6di8 2 P00766 83.21 3e-76 X-RAY
 2019-01-23 VAL B:50 B:65 34.0 0.219 E -127.3 138.2 34.0 0.219 0.0 SO4
HOH
 9.171
6.340
 N
N
 O4
O
VAL E:50 E:65 39.0 0.252 E -124.8 140.3 NA NA NA
VAL H:50 H:65 37.0 0.239 E -123.6 140.2 NA NA NA
VAL K:50 K:65 36.0 0.232 E -123.8 138.0 NA NA NA
6gch 2 P00766 83.21 3e-76 X-RAY
 1990-10-15 VAL B:50 F:65 28.0 0.181 E -125.6 146.5 28.0 0.181 0.0 HOH
 3.111
 CB
 O
7gch 2 P00766 83.21 3e-76 X-RAY
 1990-10-15 VAL B:50 F:65 33.0 0.213 E -122.8 132.7 33.0 0.213 0.0 HOH
 4.464
 N
 O
7jrx 2 P00766 83.21 3e-76 X-RAY
 2021-07-21 VAL B:50 B:65 35.0 0.226 E -122.8 133.1 35.0 0.226 0.0 HOH
 3.852
 CG2
 O
VAL F:50 b:65 33.0 0.213 E -125.1 134.0 NA NA NA
8gch 2 P00766 83.21 3e-76 X-RAY
 1992-04-15 VAL B:50 F:65 34.0 0.219 E -129.0 144.0 34.0 0.219 0.0 HOH
 5.685
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q6gpi1-f1 1 Q6GPI1 100.0 0.0 VAL A:83 A:83 29.0 0.187 E -121.3 150.2
af-p17538-f1 1 P17538 95.82 0.0 VAL A:83 A:83 28.0 0.181 E -119.2 150.3