Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 75239830 . C A CCDS32489.1:NM_001025200.3:c.217Gct>Tct_NP_001020371.3:p.73A>S Homo sapiens chymotrypsinogen B2 (CTRB2), mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1acb 1 P00766 80.82 1e-146 X-RAY
1993-10-31 ALA A:55 E:55 0.0 0.0 -90.1 145.5 0.0 0.0 0.0 HOH
2.837
O
O
1cgi 1 P00766 80.82 1e-146 X-RAY
1993-10-31 ALA A:55 E:55 1.0 0.009 -94.9 137.4 1.0 0.009 0.0 HOH
7.498
CB
O
1cgj 1 P00766 80.82 1e-146 X-RAY
1993-10-31 ALA A:55 E:55 1.0 0.009 -85.7 146.9 1.0 0.009 0.0 HOH
7.280
CB
O
1chg 1 P00766 80.82 1e-146 X-RAY
1976-11-22 ALA A:55 A:55 0.0 0.0 -89.2 162.0 0.0 0.0 0.0
1ex3 1 P00766 80.82 1e-146 X-RAY
2000-05-17 ALA A:55 A:55 0.0 0.0 E -82.4 134.5 0.0 0.0 0.0 HOH
4.644
O
O
1gcd 1 P00766 80.82 1e-146 X-RAY
1994-06-22 ALA A:55 A:55 1.0 0.009 -92.4 141.3 1.0 0.009 0.0 DEP
HOH
7.246
2.736
CB
O
P
O
1gl0 1 P00766 80.82 1e-146 X-RAY
2001-11-28 ALA A:55 E:55 0.0 0.0 -77.7 144.6 0.0 0.0 0.0 HOH
6.025
N
O
1gl1 1 P00766 80.82 1e-146 X-RAY
2001-11-28 ALA A:55 A:55 1.0 0.009 -91.1 143.4 1.0 0.009 0.0 HOH
2.748
O
O
ALA B:55 B:55 0.0 0.0 -87.3 143.8 NA NA NA
ALA C:55 C:55 1.0 0.009 -86.5 142.7 NA NA NA
1k2i 1 P00766 80.82 1e-146 X-RAY
2001-12-05 ALA A:55 1:55 1.0 0.009 -90.1 143.2 1.0 0.009 0.0 SN1
HOH
7.150
2.945
CB
O
C2
O
1oxg 1 P00766 80.82 1e-146 X-RAY
2004-05-18 ALA A:55 A:55 1.0 0.009 -84.4 141.1 1.0 0.009 0.0 HOH
2.953
O
O
1p2m 1 P00766 80.82 1e-146 X-RAY
2004-04-20 ALA A:55 A:55 0.0 0.0 -91.9 146.5 0.0 0.0 0.0 HOH
2.833
O
O
ALA C:55 C:55 1.0 0.009 -90.5 147.5 NA NA NA
1p2n 1 P00766 80.82 1e-146 X-RAY
2004-04-20 ALA A:55 A:55 0.0 0.0 -90.4 146.7 0.0 0.0 0.0 HOH
2.816
O
O
ALA C:55 C:55 0.0 0.0 -90.8 147.2 NA NA NA
1p2o 1 P00766 80.82 1e-146 X-RAY
2004-04-20 ALA A:55 A:55 0.0 0.0 -88.8 146.3 0.0 0.0 0.0 HOH
2.929
O
O
ALA C:55 C:55 0.0 0.0 -91.2 148.4 NA NA NA
1p2q 1 P00766 80.82 1e-146 X-RAY
2004-04-20 ALA A:55 A:55 0.0 0.0 -89.9 147.8 0.0 0.0 0.0 TRS
HOH
8.327
2.812
O
O
O2
O
ALA C:55 C:55 1.0 0.009 -90.3 147.9 NA NA NA
1t7c 1 P00766 80.82 1e-146 X-RAY
2005-03-08 ALA A:55 A:55 0.0 0.0 -90.6 148.3 0.0 0.0 0.0 HOH
2.767
O
O
ALA C:55 C:55 1.0 0.009 -92.0 148.5 NA NA NA
1t8l 1 P00766 80.82 1e-146 X-RAY
2005-03-08 ALA A:55 A:55 0.0 0.0 -90.6 147.1 0.0 0.0 0.0 HOH
2.888
O
O
ALA C:55 C:55 1.0 0.009 -92.1 148.6 NA NA NA
1t8m 1 P00766 80.82 1e-146 X-RAY
2005-03-08 ALA A:55 A:55 0.0 0.0 -90.5 147.2 0.0 0.0 0.0 HOH
2.849
O
O
ALA C:55 C:55 1.0 0.009 -90.9 148.6 NA NA NA
1t8n 1 P00766 80.82 1e-146 X-RAY
2005-03-08 ALA A:55 A:55 0.0 0.0 -92.4 145.6 0.0 0.0 0.0 HOH
2.774
O
O
ALA C:55 C:55 0.0 0.0 -93.3 146.2 NA NA NA
1t8o 1 P00766 80.82 1e-146 X-RAY
2005-03-08 ALA A:55 A:55 0.0 0.0 -92.4 148.1 0.0 0.0 0.0 HOH
2.801
O
O
ALA C:55 C:55 0.0 0.0 -91.4 147.8 NA NA NA
2cga 1 P00766 80.82 1e-146 X-RAY
1987-04-16 ALA A:55 A:55 0.0 0.0 -85.5 135.5 0.0 0.0 0.0 HOH
2.925
O
O
ALA B:55 B:55 0.0 0.0 -80.0 146.7 0.0 0.0 0.0 HOH
3.990
O
O
2y6t 1 P00766 80.82 1e-146 X-RAY
2011-04-20 ALA A:55 A:55 1.0 0.009 -86.3 146.3 1.0 0.009 0.0 HOH
6.639
O
O
ALA B:55 B:55 1.0 0.009 -79.6 143.8 1.0 0.009 0.0
ALA C:55 C:55 0.0 0.0 -93.2 148.8 NA NA NA
ALA D:55 D:55 1.0 0.009 -73.5 148.8 NA NA NA
3t62 1 P00766 80.82 1e-146 X-RAY
2012-08-01 ALA A:55 A:55 0.0 0.0 -94.4 144.1 0.0 0.0 0.0 HOH
2.978
O
O
ALA C:55 B:55 0.0 0.0 -86.4 145.0 NA NA NA
ALA E:55 C:55 0.0 0.0 -92.2 145.8 NA NA NA
4q2k 1 P00766 80.82 1e-146 X-RAY
2014-07-23 ALA A:55 A:55 0.0 0.0 -87.4 144.5 0.0 0.0 0.0 5BF
HOH
6.817
2.756
CB
O
C02
O
ALA B:55 B:55 1.0 0.009 -89.8 134.1 NA NA NA
ALA C:55 C:55 0.0 0.0 -116.3 143.4 NA NA NA
ALA D:55 D:55 0.0 0.0 -80.4 141.6 0.0 0.0 0.0 5BF
HOH
6.839
2.937
CB
O
C05
O
5j4q 1 P00766 80.82 1e-146 X-RAY
2017-04-12 ALA A:55 A:55 0.0 0.0 -96.0 141.5 0.0 0.0 0.0 HOH
4.459
O
O
5j4s 1 P00766 80.82 1e-146 X-RAY
2017-04-12 ALA A:55 A:55 1.0 0.009 -88.6 143.7 1.0 0.009 0.0 HOH
2.906
O
O
7kty 1 P00766 80.82 1e-146 X-RAY
2021-03-10 ALA A:55 A:55 1.0 0.009 -88.3 147.7 1.0 0.009 0.0 SO4
SO4
HOH
7.004
7.617
2.878
O
O
O
O2
O3
O
7ktz 1 P00766 80.82 1e-146 X-RAY
2021-03-10 ALA A:55 A:55 0.0 0.0 -85.8 144.6 0.0 0.0 0.0 SO4
SO4
HOH
7.427
6.974
2.825
O
O
O
O2
O3
O
7ku0 1 P00766 80.82 1e-146 X-RAY
2021-03-10 ALA A:55 A:55 0.0 0.0 -84.9 143.5 0.0 0.0 0.0 SO4
SO4
HOH
7.065
7.339
2.791
O
O
O
O2
O3
O
7ku1 1 P00766 80.82 1e-146 X-RAY
2021-03-10 ALA A:55 A:55 0.0 0.0 -96.1 148.3 0.0 0.0 0.0
7ku2 1 P00766 80.82 1e-146 X-RAY
2021-03-10 ALA A:55 A:55 1.0 0.009 -92.8 146.7 1.0 0.009 0.0 HOH
2.932
O
O
7ku3 1 P00766 80.82 1e-146 X-RAY
2021-03-10 ALA A:55 A:55 0.0 0.0 -88.5 145.1 0.0 0.0 0.0 SO4
SO4
HOH
6.827
7.441
2.809
O
O
O
O2
O3
O
1kdq 1 P07338 89.31 3e-84 X-RAY
2003-06-10 ALA A:40 A:55 19.0 0.165 -111.8 154.9 0.0 0.0 0.165 B:P07338:0.165
HOH
8.604
CB
O
2jet 2 P07338 89.84 6e-83 X-RAY
2007-09-18 ALA B:37 B:55 19.0 0.165 -90.4 154.9 0.0 0.0 0.165 C:P07338:0.165
HOH
5.819
N
O
1ab9 2 P00766 83.21 3e-76 X-RAY
1997-08-20 ALA B:40 B:55 23.0 0.2 -90.6 138.4 1.0 0.009 0.191 C:P00766:0.191
HOH
2.787
O
O
1afq 2 P00766 83.21 3e-76 X-RAY
1997-09-17 ALA B:40 B:55 22.0 0.191 -88.2 143.0 1.0 0.009 0.182 C:P00766:0.183
0FG
HOH
7.653
2.898
CB
O
CD11
O
1ca0 2 P00766 83.21 3e-76 X-RAY
1997-07-23 ALA B:40 B:55 22.0 0.191 -95.0 143.0 0.0 0.0 0.191 C:P00766:0.191
HOH
2.814
O
O
ALA F:40 G:55 20.0 0.174 -91.3 147.5 NA NA NA
1cbw 2 P00766 83.21 3e-76 X-RAY
1997-07-23 ALA B:40 B:55 28.0 0.243 -77.1 145.0 0.0 0.0 0.243 C:P00766:0.243
HOH
4.176
O
O
ALA F:40 G:55 23.0 0.2 -79.6 139.9 NA NA NA
1cho 2 P00766 83.21 3e-76 X-RAY
1988-07-16 ALA B:40 F:55 22.0 0.191 -90.4 144.3 1.0 0.009 0.182 C:P00766:0.183
HOH
2.875
O
O
1gct 2 P00766 83.21 3e-76 X-RAY
1991-10-15 ALA B:40 B:55 22.0 0.191 -89.3 143.6 1.0 0.009 0.182 C:P00766:0.183
HOH
2.831
O
O
1gg6 2 P00766 83.21 3e-76 X-RAY
2000-09-20 ALA B:40 B:55 21.0 0.183 -90.0 141.4 0.0 0.0 0.183 C:P00766:0.183
APF
HOH
7.259
2.895
CB
O
C2
O
1ggd 2 P00766 83.21 3e-76 X-RAY
2000-09-20 ALA B:40 B:55 22.0 0.191 -89.1 139.2 1.0 0.009 0.182 C:P00766:0.183
FAF
HOH
6.965
2.897
CB
O
CW
O
1gha 2 P00766 83.21 3e-76 X-RAY
1994-06-22 ALA B:40 F:55 22.0 0.191 -78.9 136.9 0.0 0.0 0.191 C:P00766:0.191
HOH
3.083
O
O
1ghb 2 P00766 83.21 3e-76 X-RAY
1994-06-22 ALA B:40 F:55 21.0 0.183 -90.8 141.4 0.0 0.0 0.183 C:P00766:0.183
TRP
IPA
IPA
IPA
HOH
8.142
7.560
5.067
9.188
2.689
CB
CB
O
O
O
CD1
O2
C1
C3
O
1gmc 2 P00766 83.21 3e-76 X-RAY
1993-10-31 ALA B:40 F:55 22.0 0.191 -88.5 142.2 1.0 0.009 0.182 C:P00766:0.183
HOH
2.804
O
O
1gmd 2 P00766 83.21 3e-76 X-RAY
1993-10-31 ALA B:40 F:55 22.0 0.191 -84.0 137.1 0.0 0.0 0.191 C:P00766:0.191
HEX
HEX
HOH
6.823
7.694
3.186
O
O
O
C6
C6
O
1gmh 2 P00766 83.21 3e-76 X-RAY
1994-09-30 ALA B:40 F:55 22.0 0.191 -89.4 132.9 0.0 0.0 0.191 C:P00766:0.191
ISP
HOH
6.851
2.660
CB
O
P
O
1hja 2 P00766 83.21 3e-76 X-RAY
1998-01-14 ALA B:40 B:55 20.0 0.174 -88.5 145.8 0.0 0.0 0.174 C:P00766:0.174
HOH
3.074
O
O
1mtn 2 P00766 83.21 3e-76 X-RAY
1996-08-17 ALA B:40 B:55 25.0 0.217 -77.6 148.3 0.0 0.0 0.217 C:P00766:0.217
HOH
3.205
O
O
ALA F:40 F:55 24.0 0.209 -86.2 136.2 NA NA NA
1n8o 2 P00766 83.21 3e-76 X-RAY
2002-12-18 ALA B:40 B:55 22.0 0.191 -93.7 139.9 0.0 0.0 0.191 C:P00766:0.191
HOH
2.842
O
O
1vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 ALA B:40 B:55 21.0 0.183 -88.0 142.0 1.0 0.009 0.174 C:P00766:0.174
V36
HOH
6.950
2.853
CB
O
B
O
1yph 2 P00766 83.21 3e-76 X-RAY
2006-02-14 ALA B:40 C:55 20.0 0.174 -89.1 142.2 0.0 0.0 0.174 C:P00766:0.174
SO4
HOH
8.203
2.890
O
O
O2
O
ALA E:40 D:55 18.0 0.157 -89.7 140.8 0.0 0.0 0.157 F:P00766:0.157
HOH
2.897
O
O
2cha 2 P00766 83.21 3e-76 X-RAY
1977-01-18 ALA B:40 B:55 25.0 0.217 -98.9 148.6 0.0 0.0 0.217 C:P00766:0.217
TSU
HOH
7.961
5.576
CB
N
S
O
ALA E:40 F:55 26.0 0.226 -98.9 148.6 0.0 0.0 0.226 F:P00766:0.226
TSU
7.961
CB
S
2gch 2 P00766 83.21 3e-76 X-RAY
1980-07-09 ALA B:40 F:55 20.0 0.174 -95.7 138.9 0.0 0.0 0.174 C:P00766:0.174
HOH
2.974
O
O
2gct 2 P00766 83.21 3e-76 X-RAY
1991-10-15 ALA B:40 B:55 21.0 0.183 -93.0 145.2 0.0 0.0 0.183 C:P00766:0.183
HOH
2.918
O
O
2gmt 2 P00766 83.21 3e-76 X-RAY
1994-11-01 ALA B:40 B:55 26.0 0.226 -78.3 129.4 1.0 0.009 0.217 C:P00766:0.217
HIN
HOH
6.098
2.955
CB
O
C2
O
2p8o 2 P00766 83.21 3e-76 X-RAY
2007-05-08 ALA B:40 B:55 21.0 0.183 -89.0 143.2 1.0 0.009 0.174 C:P00766:0.174
BVA
HOH
7.457
2.932
CB
O
O12
O
2vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 ALA B:40 B:55 21.0 0.183 -93.5 145.5 1.0 0.009 0.174 C:P00766:0.174
V35
HOH
6.100
2.848
CB
O
B
O
3bg4 2 P00766 83.21 3e-76 X-RAY
2008-07-29 ALA B:40 B:55 21.0 0.183 -90.3 140.4 0.0 0.0 0.183 C:P00766:0.183
HOH
3.894
O
O
3gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 ALA B:40 B:55 20.0 0.174 -90.0 149.9 0.0 0.0 0.174 C:P00766:0.174
OAC
HOH
5.742
1.869
CB
O
O
O
3gct 2 P00766 83.21 3e-76 X-RAY
1991-10-15 ALA B:40 F:55 22.0 0.191 -87.7 145.7 1.0 0.009 0.182 C:P00766:0.183
HOH
2.869
O
O
3ru4 4 P00766 83.21 3e-76 X-RAY
2012-08-29 ALA D:40 D:55 21.0 0.183 -84.7 140.3 NA NA NA
3vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 ALA B:40 B:55 21.0 0.183 -93.5 142.0 1.0 0.009 0.174 C:P00766:0.174
SRB
HOH
6.841
2.822
CB
O
O1B
O
4cha 2 P00766 83.21 3e-76 X-RAY
1985-04-01 ALA B:40 B:55 20.0 0.174 -92.5 146.0 0.0 0.0 0.174 C:P00766:0.174
HOH
3.094
O
O
ALA E:40 F:55 18.0 0.157 -92.9 139.4 0.0 0.0 0.157 F:P00766:0.157
HOH
3.040
O
O
4gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 ALA B:40 F:55 20.0 0.174 -90.1 147.3 0.0 0.0 0.174 C:P00766:0.174
DMC
HOH
5.030
1.943
CB
O
O
O
4vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 ALA B:40 B:55 23.0 0.2 -87.4 140.9 1.0 0.009 0.191 C:P00766:0.191
SRD
HOH
5.924
2.847
CB
O
B
O
5cha 2 P00766 83.21 3e-76 X-RAY
1985-04-01 ALA B:40 B:55 21.0 0.183 -84.4 145.8 0.0 0.0 0.183 C:P00766:0.183
HOH
3.424
O
O
ALA E:40 F:55 21.0 0.183 -92.7 145.1 0.0 0.0 0.183 F:P00766:0.183
HOH
2.092
O
O
5gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 ALA B:40 F:55 24.0 0.209 -93.7 145.1 0.0 0.0 0.209 C:P00766:0.209
HOH
2.222
O
O
5r42 2 P00766 83.21 3e-76 X-RAY
2021-09-01 ALA B:40 B:55 22.0 0.191 -89.1 140.3 0.0 0.0 0.191 C:P00766:0.191
HOH
2.952
O
O
5r43 2 P00766 83.21 3e-76 X-RAY
2021-09-01 ALA B:40 B:55 21.0 0.183 -88.0 140.6 0.0 0.0 0.183 C:P00766:0.183
HOH
2.915
O
O
5r44 2 P00766 83.21 3e-76 X-RAY
2021-09-01 ALA B:40 B:55 22.0 0.191 -88.9 139.8 0.0 0.0 0.191 C:P00766:0.191
HOH
2.935
O
O
5r45 2 P00766 83.21 3e-76 X-RAY
2021-09-01 ALA B:40 B:55 22.0 0.191 -89.5 141.2 0.0 0.0 0.191 C:P00766:0.191
HOH
2.904
O
O
5r46 2 P00766 83.21 3e-76 X-RAY
2021-09-01 ALA B:40 B:55 22.0 0.191 -87.5 139.6 0.0 0.0 0.191 C:P00766:0.191
HOH
2.951
O
O
5r47 2 P00766 83.21 3e-76 X-RAY
2021-09-01 ALA B:40 B:55 21.0 0.183 -89.4 140.1 0.0 0.0 0.183 C:P00766:0.183
HOH
2.903
O
O
5r48 2 P00766 83.21 3e-76 X-RAY
2021-09-01 ALA B:40 B:55 22.0 0.191 -88.0 140.0 0.0 0.0 0.191 C:P00766:0.191
HOH
2.949
O
O
5r49 2 P00766 83.21 3e-76 X-RAY
2021-09-01 ALA B:40 B:55 21.0 0.183 -88.3 140.1 0.0 0.0 0.183 C:P00766:0.183
HOH
2.906
O
O
5r4a 2 P00766 83.21 3e-76 X-RAY
2021-09-01 ALA B:40 B:55 23.0 0.2 -87.4 140.7 1.0 0.009 0.191 C:P00766:0.191
HOH
2.963
O
O
5r4b 2 P00766 83.21 3e-76 X-RAY
2021-09-01 ALA B:40 B:55 22.0 0.191 -87.5 139.0 0.0 0.0 0.191 C:P00766:0.191
HOH
2.937
O
O
5r4c 2 P00766 83.21 3e-76 X-RAY
2021-09-01 ALA B:40 B:55 23.0 0.2 -88.0 141.1 1.0 0.009 0.191 C:P00766:0.191
HOH
2.975
O
O
5r4d 2 P00766 83.21 3e-76 X-RAY
2021-09-01 ALA B:40 B:55 22.0 0.191 -88.8 139.6 0.0 0.0 0.191 C:P00766:0.191
HOH
2.945
O
O
6cha 2 P00766 83.21 3e-76 X-RAY
1987-04-16 ALA B:40 B:55 20.0 0.174 -87.0 156.7 0.0 0.0 0.174 C:P00766:0.174
PBA
HOH
7.745
2.937
CB
O
B
O
ALA E:40 F:55 21.0 0.183 -80.2 150.6 0.0 0.0 0.183 F:P00766:0.183
PBA
HOH
7.820
3.157
CB
O
O1
O
6di8 2 P00766 83.21 3e-76 X-RAY
2019-01-23 ALA B:40 B:55 21.0 0.183 -88.9 142.5 0.0 0.0 0.183 C:P00766:0.183
SO4
HOH
7.417
2.788
O
O
O2
O
ALA E:40 E:55 20.0 0.174 -88.3 143.8 NA NA NA
ALA H:40 H:55 22.0 0.191 -88.9 143.1 NA NA NA
ALA K:40 K:55 20.0 0.174 -89.4 143.8 NA NA NA
6gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 ALA B:40 F:55 20.0 0.174 -96.9 131.0 0.0 0.0 0.174 C:P00766:0.174
APF
HOH
7.179
3.575
CB
O
F11
O
7gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 ALA B:40 F:55 19.0 0.165 -80.5 157.4 0.0 0.0 0.165 C:P00766:0.165
LPF
HOH
6.513
3.434
CB
O
CA4
O
7jrx 2 P00766 83.21 3e-76 X-RAY
2021-07-21 ALA B:40 B:55 21.0 0.183 -87.2 141.3 1.0 0.009 0.174 C:P00766:0.174
HOH
2.924
O
O
ALA F:40 b:55 22.0 0.191 -86.9 141.6 NA NA NA
8gch 2 P00766 83.21 3e-76 X-RAY
1992-04-15 ALA B:40 F:55 21.0 0.183 -94.1 139.3 0.0 0.0 0.183 C:P00766:0.183
HOH
2.980
O
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q6gpi1-f1 1 Q6GPI1 100.0 0.0 ALA A:73 A:73 0.0 0.0 -80.2 146.2
af-p17538-f1 1 P17538 95.82 0.0 ALA A:73 A:73 0.0 0.0 -78.2 151.7