Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 75256734 . G A CCDS32490.1:NM_001906.4:c.121Gtc>Atc_NP_001897.4:p.41V>I Homo sapiens chymotrypsinogen B1 (CTRB1), mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1acb 1 P00766 81.63 3e-148 X-RAY
1993-10-31 VAL A:23 E:23 44.0 0.284 -82.6 132.0 44.0 0.284 0.0 HOH
3.072
N
O
1cgi 1 P00766 81.63 3e-148 X-RAY
1993-10-31 VAL A:23 E:23 51.0 0.329 -78.1 129.9 51.0 0.329 0.0 HOH
3.814
O
O
1cgj 1 P00766 81.63 3e-148 X-RAY
1993-10-31 VAL A:23 E:23 51.0 0.329 -73.6 127.3 51.0 0.329 0.0 HOH
4.581
O
O
1chg 1 P00766 81.63 3e-148 X-RAY
1976-11-22 VAL A:23 A:23 43.0 0.277 -95.0 104.8 43.0 0.277 0.0
1ex3 1 P00766 81.63 3e-148 X-RAY
2000-05-17 VAL A:23 A:23 47.0 0.303 -69.2 129.6 47.0 0.303 0.0 HOH
4.419
CG2
O
1gcd 1 P00766 81.63 3e-148 X-RAY
1994-06-22 VAL A:23 A:23 53.0 0.342 -78.5 132.2 53.0 0.342 0.0 HOH
2.854
N
O
1gl0 1 P00766 81.63 3e-148 X-RAY
2001-11-28 VAL A:23 E:23 47.0 0.303 -73.9 131.6 47.0 0.303 0.0 HOH
3.058
N
O
1gl1 1 P00766 81.63 3e-148 X-RAY
2001-11-28 VAL A:23 A:23 55.0 0.355 -72.9 129.4 55.0 0.355 0.0 HOH
3.185
N
O
VAL B:23 B:23 51.0 0.329 -74.5 127.1 NA NA NA
VAL C:23 C:23 48.0 0.31 -74.3 129.6 NA NA NA
1k2i 1 P00766 81.63 3e-148 X-RAY
2001-12-05 VAL A:23 1:23 49.0 0.316 -73.4 131.0 49.0 0.316 0.0 HOH
3.069
N
O
1oxg 1 P00766 81.63 3e-148 X-RAY
2004-05-18 VAL A:23 A:23 28.0 0.181 -65.0 133.7 28.0 0.181 0.0 HOH
2.961
N
O
1p2m 1 P00766 81.63 3e-148 X-RAY
2004-04-20 VAL A:23 A:23 45.0 0.29 -71.0 131.6 45.0 0.29 0.0 HOH
2.910
N
O
VAL C:23 C:23 48.0 0.31 -68.5 131.8 NA NA NA
1p2n 1 P00766 81.63 3e-148 X-RAY
2004-04-20 VAL A:23 A:23 46.0 0.297 -69.8 131.3 46.0 0.297 0.0 HOH
3.017
N
O
VAL C:23 C:23 49.0 0.316 -70.2 131.0 NA NA NA
1p2o 1 P00766 81.63 3e-148 X-RAY
2004-04-20 VAL A:23 A:23 47.0 0.303 -69.4 132.0 47.0 0.303 0.0 HOH
3.169
N
O
VAL C:23 C:23 46.0 0.297 -72.3 132.1 NA NA NA
1p2q 1 P00766 81.63 3e-148 X-RAY
2004-04-20 VAL A:23 A:23 47.0 0.303 -68.3 131.6 47.0 0.303 0.0 HOH
2.938
N
O
VAL C:23 C:23 47.0 0.303 -67.8 130.1 NA NA NA
1t7c 1 P00766 81.63 3e-148 X-RAY
2005-03-08 VAL A:23 A:23 46.0 0.297 -67.7 129.8 46.0 0.297 0.0 HOH
2.952
N
O
VAL C:23 C:23 47.0 0.303 -70.3 130.9 NA NA NA
1t8l 1 P00766 81.63 3e-148 X-RAY
2005-03-08 VAL A:23 A:23 46.0 0.297 -71.4 130.5 46.0 0.297 0.0 HOH
2.921
N
O
VAL C:23 C:23 47.0 0.303 -69.0 130.3 NA NA NA
1t8m 1 P00766 81.63 3e-148 X-RAY
2005-03-08 VAL A:23 A:23 46.0 0.297 -68.7 131.5 46.0 0.297 0.0 HOH
3.026
N
O
VAL C:23 C:23 46.0 0.297 -67.5 132.0 NA NA NA
1t8n 1 P00766 81.63 3e-148 X-RAY
2005-03-08 VAL A:23 A:23 45.0 0.29 -68.0 131.3 45.0 0.29 0.0 HOH
2.911
N
O
VAL C:23 C:23 46.0 0.297 -68.2 130.4 NA NA NA
1t8o 1 P00766 81.63 3e-148 X-RAY
2005-03-08 VAL A:23 A:23 45.0 0.29 -72.0 129.8 45.0 0.29 0.0 HOH
2.948
N
O
VAL C:23 C:23 49.0 0.316 -71.2 132.1 NA NA NA
2cga 1 P00766 81.63 3e-148 X-RAY
1987-04-16 VAL A:23 A:23 52.0 0.335 -78.0 128.1 52.0 0.335 0.0 HOH
3.221
N
O
VAL B:23 B:23 47.0 0.303 -79.9 123.9 10.0 0.065 0.238 A:P00766:0.239
HOH
3.054
N
O
2y6t 1 P00766 81.63 3e-148 X-RAY
2011-04-20 VAL A:23 A:23 44.0 0.284 -72.1 128.6 44.0 0.284 0.0 HOH
2.832
N
O
VAL B:23 B:23 46.0 0.297 -70.1 123.7 46.0 0.297 0.0 HOH
2.679
N
O
VAL C:23 C:23 53.0 0.342 -70.2 120.6 NA NA NA
VAL D:23 D:23 44.0 0.284 -69.6 126.7 NA NA NA
3t62 1 P00766 81.63 3e-148 X-RAY
2012-08-01 VAL A:23 A:23 50.0 0.323 -59.8 124.3 50.0 0.323 0.0 HOH
2.990
N
O
VAL C:23 B:23 46.0 0.297 -66.5 123.8 NA NA NA
VAL E:23 C:23 42.0 0.271 -69.6 118.9 NA NA NA
4q2k 1 P00766 81.63 3e-148 X-RAY
2014-07-23 VAL A:23 A:23 51.0 0.329 -60.1 129.8 51.0 0.329 0.0 HOH
3.217
N
O
VAL B:23 B:23 48.0 0.31 -53.5 138.3 NA NA NA
VAL C:23 C:23 54.0 0.348 -53.2 125.2 NA NA NA
VAL D:23 D:23 45.0 0.29 -53.8 125.6 45.0 0.29 0.0 HOH
3.053
N
O
5j4q 1 P00766 81.63 3e-148 X-RAY
2017-04-12 VAL A:23 A:23 48.0 0.31 -53.6 122.7 48.0 0.31 0.0 HOH
2.952
N
O
5j4s 1 P00766 81.63 3e-148 X-RAY
2017-04-12 VAL A:23 A:23 48.0 0.31 -57.3 127.7 48.0 0.31 0.0 HOH
2.191
H
O
7kty 1 P00766 81.63 3e-148 X-RAY
2021-03-10 VAL A:23 A:23 50.0 0.323 -70.2 129.6 50.0 0.323 0.0 HOH
2.880
N
O
7ktz 1 P00766 81.63 3e-148 X-RAY
2021-03-10 VAL A:23 A:23 49.0 0.316 -67.2 131.4 49.0 0.316 0.0 HOH
2.802
N
O
7ku0 1 P00766 81.63 3e-148 X-RAY
2021-03-10 VAL A:23 A:23 50.0 0.323 -68.8 129.5 50.0 0.323 0.0 HOH
2.878
N
O
7ku1 1 P00766 81.63 3e-148 X-RAY
2021-03-10 VAL A:23 A:23 45.0 0.29 -66.9 132.0 45.0 0.29 0.0 HOH
3.897
CG1
O
7ku2 1 P00766 81.63 3e-148 X-RAY
2021-03-10 VAL A:23 A:23 47.0 0.303 -68.2 133.7 47.0 0.303 0.0 HOH
2.825
N
O
7ku3 1 P00766 81.63 3e-148 X-RAY
2021-03-10 VAL A:23 A:23 49.0 0.316 -63.5 129.9 49.0 0.316 0.0 HOH
2.788
N
O
1dlk 2 P00766 80.87 2e-137 X-RAY
2000-05-03 VAL B:8 B:23 99.0 0.639 -75.6 136.7 46.0 0.297 0.342 A:P00766:0.342
HOH
2.862
N
O
VAL D:8 D:23 100.0 0.645 -70.6 134.3 NA NA NA
1kdq 1 P07338 89.31 3e-84 X-RAY
2003-06-10 ILE A:8 A:23 127.0 0.726 -70.8 128.1 118.0 0.674 0.052 B:P07338:0.051
HOH
3.987
CA
O
2jet 2 P07338 89.84 5e-83 X-RAY
2007-09-18 ILE B:5 B:23 126.0 0.72 -74.5 138.0 66.0 0.377 0.343 A:P07338:0.326
C:P07338:0.023
HOH
3.201
N
O
1ab9 2 P00766 83.21 3e-76 X-RAY
1997-08-20 VAL B:8 B:23 108.0 0.697 -73.3 127.4 51.0 0.329 0.368 C:P00766:0.032
A:P00766:0.361
HOH
2.979
N
O
1afq 2 P00766 83.21 3e-76 X-RAY
1997-09-17 VAL B:8 B:23 106.0 0.684 -69.0 129.6 49.0 0.316 0.368 A:P00766:0.355
C:P00766:0.039
HOH
3.109
N
O
1ca0 2 P00766 83.21 3e-76 X-RAY
1997-07-23 VAL B:8 B:23 102.0 0.658 -72.3 129.9 44.0 0.284 0.374 C:P00766:0.026
A:P00766:0.374
HOH
3.142
N
O
VAL F:8 G:23 96.0 0.619 -83.2 131.3 NA NA NA
1cbw 2 P00766 83.21 3e-76 X-RAY
1997-07-23 VAL B:8 B:23 102.0 0.658 -86.6 117.2 43.0 0.277 0.381 C:P00766:0.019
A:P00767:0.381
HOH
2.824
N
O
VAL F:8 G:23 107.0 0.69 -78.0 122.5 NA NA NA
1cho 2 P00766 83.21 3e-76 X-RAY
1988-07-16 VAL B:8 F:23 104.0 0.671 -83.0 135.6 47.0 0.303 0.368 C:P00766:0.013
A:P00766:0.361
HOH
2.843
N
O
1gct 2 P00766 83.21 3e-76 X-RAY
1991-10-15 VAL B:8 B:23 107.0 0.69 -73.2 132.2 52.0 0.335 0.355 A:P00766:0.348
C:P00766:0.019
HOH
2.945
N
O
1gg6 2 P00766 83.21 3e-76 X-RAY
2000-09-20 VAL B:8 B:23 104.0 0.671 -71.2 130.0 50.0 0.323 0.348 C:P00766:0.032
A:P00766:0.342
HOH
2.985
N
O
1ggd 2 P00766 83.21 3e-76 X-RAY
2000-09-20 VAL B:8 B:23 105.0 0.677 -72.1 127.2 49.0 0.316 0.361 C:P00766:0.032
A:P00766:0.361
HOH
3.017
N
O
1gha 2 P00766 83.21 3e-76 X-RAY
1994-06-22 VAL B:8 F:23 106.0 0.684 -78.3 127.2 49.0 0.316 0.368 C:P00766:0.019
A:P00766:0.355
HOH
3.007
N
O
1ghb 2 P00766 83.21 3e-76 X-RAY
1994-06-22 VAL B:8 F:23 103.0 0.665 -83.7 131.2 47.0 0.303 0.362 A:P00766:0.342
C:P00766:0.058
HEX
HOH
6.433
3.273
CG2
N
C6
O
1gmc 2 P00766 83.21 3e-76 X-RAY
1993-10-31 VAL B:8 F:23 107.0 0.69 -73.9 137.1 49.0 0.316 0.374 A:P00766:0.361
C:P00766:0.026
HOH
2.834
N
O
1gmd 2 P00766 83.21 3e-76 X-RAY
1993-10-31 VAL B:8 F:23 103.0 0.665 -77.7 127.6 48.0 0.31 0.355 A:P00766:0.355
C:P00766:0.019
HEX
HEX
HOH
8.332
8.439
2.826
N
O
N
C1
C4
O
1gmh 2 P00766 83.21 3e-76 X-RAY
1994-09-30 VAL B:8 F:23 107.0 0.69 -75.1 126.5 54.0 0.348 0.342 A:P00766:0.335
C:P00766:0.026
HOH
3.308
N
O
1hja 2 P00766 83.21 3e-76 X-RAY
1998-01-14 VAL B:8 B:23 104.0 0.671 -67.6 133.0 43.0 0.277 0.394 C:P00766:0.045
A:P00766:0.381
HOH
3.223
N
O
1mtn 2 P00766 83.21 3e-76 X-RAY
1996-08-17 VAL B:8 B:23 99.0 0.639 -79.5 122.5 47.0 0.303 0.336 C:P00766:0.013
A:P00766:0.329
HOH
7.457
O
O
VAL F:8 F:23 105.0 0.677 -63.0 134.3 NA NA NA
1n8o 2 P00766 83.21 3e-76 X-RAY
2002-12-18 VAL B:8 B:23 105.0 0.677 -69.6 130.6 50.0 0.323 0.354 C:P00766:0.013
A:P00766:0.355
HOH
3.006
N
O
1vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 VAL B:8 B:23 107.0 0.69 -74.2 125.7 48.0 0.31 0.38 C:P00766:0.052
A:P00766:0.374
HOH
2.839
N
O
1yph 2 P00766 83.21 3e-76 X-RAY
2006-02-14 VAL B:8 C:23 106.0 0.684 -70.4 127.2 49.0 0.316 0.368 C:P00766:0.026
A:P00766:0.361
HOH
3.008
N
O
VAL E:8 D:23 104.0 0.671 -62.4 132.5 48.0 0.31 0.361 F:P00766:0.013
D:P00766:0.361
HOH
2.951
N
O
2cha 2 P00766 83.21 3e-76 X-RAY
1977-01-18 VAL B:8 B:23 109.0 0.703 -68.6 130.0 69.0 0.445 0.258 C:P00766:0.032
A:P00766:0.226
HOH
2.742
N
O
VAL E:8 F:23 111.0 0.716 -68.6 130.0 70.0 0.452 0.264 F:P00766:0.039
D:P00766:0.239
2gch 2 P00766 83.21 3e-76 X-RAY
1980-07-09 VAL B:8 F:23 105.0 0.677 -76.1 130.8 42.0 0.271 0.406 C:P00766:0.045
A:P00766:0.4
HOH
2.990
N
O
2gct 2 P00766 83.21 3e-76 X-RAY
1991-10-15 VAL B:8 B:23 109.0 0.703 -72.8 126.7 50.0 0.323 0.38 A:P00766:0.381
C:P00766:0.013
HOH
2.909
N
O
2gmt 2 P00766 83.21 3e-76 X-RAY
1994-11-01 VAL B:8 B:23 105.0 0.677 -71.8 139.3 49.0 0.316 0.361 C:P00766:0.026
A:P00766:0.348
HOH
3.007
N
O
2p8o 2 P00766 83.21 3e-76 X-RAY
2007-05-08 VAL B:8 B:23 105.0 0.677 -60.8 129.1 48.0 0.31 0.367 C:P00766:0.045
A:P00766:0.361
HOH
2.855
N
O
2vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 VAL B:8 B:23 108.0 0.697 -77.3 128.0 50.0 0.323 0.374 C:P00766:0.045
A:P00766:0.361
HOH
2.996
N
O
3bg4 2 P00766 83.21 3e-76 X-RAY
2008-07-29 VAL B:8 B:23 103.0 0.665 -76.2 126.5 45.0 0.29 0.375 C:P00766:0.045
A:P00766:0.361
HOH
2.851
N
O
3gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 VAL B:8 B:23 110.0 0.71 -87.5 130.1 46.0 0.297 0.413 C:P00766:0.039
A:P00766:0.4
HOH
3.138
N
O
3gct 2 P00766 83.21 3e-76 X-RAY
1991-10-15 VAL B:8 F:23 107.0 0.69 -73.8 133.0 48.0 0.31 0.38 C:P00766:0.032
A:P00766:0.374
HOH
2.893
N
O
3ru4 4 P00766 83.21 3e-76 X-RAY
2012-08-29 VAL D:8 D:23 107.0 0.69 -63.9 130.1 NA NA NA
3vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 VAL B:8 B:23 105.0 0.677 -77.4 127.9 46.0 0.297 0.38 A:P00766:0.368
C:P00766:0.039
HOH
2.954
N
O
4cha 2 P00766 83.21 3e-76 X-RAY
1985-04-01 VAL B:8 B:23 107.0 0.69 -72.1 131.5 49.0 0.316 0.374 C:P00766:0.039
A:P00766:0.361
HOH
2.944
N
O
VAL E:8 F:23 106.0 0.684 -75.4 132.4 52.0 0.335 0.349 F:P00766:0.013
D:P00766:0.335
HOH
2.948
N
O
4gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 VAL B:8 F:23 110.0 0.71 -73.2 134.2 52.0 0.335 0.375 C:P00766:0.032
A:P00766:0.361
HOH
3.290
N
O
4vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 VAL B:8 B:23 105.0 0.677 -80.0 124.8 49.0 0.316 0.361 C:P00766:0.026
A:P00766:0.355
HOH
2.925
N
O
5cha 2 P00766 83.21 3e-76 X-RAY
1985-04-01 VAL B:8 B:23 107.0 0.69 -75.5 128.9 76.0 0.49 0.2 C:P00766:0.039
A:P00766:0.161
HOH
2.994
N
O
VAL E:8 F:23 107.0 0.69 -80.6 132.5 72.0 0.465 0.225 F:P00766:0.019
D:P00766:0.206
HOH
3.128
N
O
5gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 VAL B:8 F:23 107.0 0.69 -81.5 131.7 49.0 0.316 0.374 A:P00766:0.368
C:P00766:0.019
HOH
3.125
N
O
5r42 2 P00766 83.21 3e-76 X-RAY
2021-09-01 VAL B:8 B:23 104.0 0.671 -66.8 129.9 49.0 0.316 0.355 C:P00766:0.032
A:P00766:0.348
HOH
3.028
N
O
5r43 2 P00766 83.21 3e-76 X-RAY
2021-09-01 VAL B:8 B:23 105.0 0.677 -64.1 128.5 48.0 0.31 0.367 C:P00766:0.039
A:P00766:0.355
HOH
2.961
N
O
5r44 2 P00766 83.21 3e-76 X-RAY
2021-09-01 VAL B:8 B:23 104.0 0.671 -67.0 129.7 49.0 0.316 0.355 A:P00766:0.348
C:P00766:0.032
HOH
3.025
N
O
5r45 2 P00766 83.21 3e-76 X-RAY
2021-09-01 VAL B:8 B:23 105.0 0.677 -62.8 128.0 47.0 0.303 0.374 A:P00766:0.361
C:P00766:0.039
HOH
2.973
N
O
5r46 2 P00766 83.21 3e-76 X-RAY
2021-09-01 VAL B:8 B:23 104.0 0.671 -68.0 129.6 49.0 0.316 0.355 A:P00766:0.355
C:P00766:0.032
HOH
3.027
N
O
5r47 2 P00766 83.21 3e-76 X-RAY
2021-09-01 VAL B:8 B:23 103.0 0.665 -62.2 128.5 48.0 0.31 0.355 A:P00766:0.348
C:P00766:0.032
HOH
2.948
N
O
5r48 2 P00766 83.21 3e-76 X-RAY
2021-09-01 VAL B:8 B:23 104.0 0.671 -67.6 129.9 48.0 0.31 0.361 C:P00766:0.039
A:P00766:0.355
HOH
3.026
N
O
5r49 2 P00766 83.21 3e-76 X-RAY
2021-09-01 VAL B:8 B:23 104.0 0.671 -62.2 126.9 48.0 0.31 0.361 C:P00766:0.039
A:P00766:0.355
HOH
2.965
N
O
5r4a 2 P00766 83.21 3e-76 X-RAY
2021-09-01 VAL B:8 B:23 104.0 0.671 -67.2 128.9 49.0 0.316 0.355 A:P00766:0.355
C:P00766:0.032
HOH
3.038
N
O
5r4b 2 P00766 83.21 3e-76 X-RAY
2021-09-01 VAL B:8 B:23 104.0 0.671 -64.2 130.1 49.0 0.316 0.355 C:P00766:0.039
A:P00766:0.342
HOH
2.980
N
O
5r4c 2 P00766 83.21 3e-76 X-RAY
2021-09-01 VAL B:8 B:23 104.0 0.671 -68.1 129.4 50.0 0.323 0.348 A:P00766:0.342
C:P00766:0.026
HOH
3.039
N
O
5r4d 2 P00766 83.21 3e-76 X-RAY
2021-09-01 VAL B:8 B:23 104.0 0.671 -63.9 130.6 48.0 0.31 0.361 C:P00766:0.039
A:P00766:0.348
HOH
2.983
N
O
6cha 2 P00766 83.21 3e-76 X-RAY
1987-04-16 VAL B:8 B:23 108.0 0.697 -83.8 126.7 80.0 0.516 0.181 A:P00766:0.155
C:P00766:0.026
HOH
3.474
N
O
VAL E:8 F:23 107.0 0.69 -68.0 127.7 68.0 0.439 0.251 F:P00766:0.026
D:P00766:0.226
HOH
3.411
N
O
6di8 2 P00766 83.21 3e-76 X-RAY
2019-01-23 VAL B:8 B:23 104.0 0.671 -64.1 133.2 49.0 0.316 0.355 A:P00766:0.355
C:P00766:0.019
HOH
2.806
N
O
VAL E:8 E:23 103.0 0.665 -64.4 132.4 NA NA NA
VAL H:8 H:23 103.0 0.665 -64.1 133.3 NA NA NA
VAL K:8 K:23 104.0 0.671 -65.8 134.1 NA NA NA
6gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 VAL B:8 F:23 105.0 0.677 -76.3 125.3 48.0 0.31 0.367 C:P00766:0.032
A:P00766:0.348
HOH
2.620
CG1
O
7gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 VAL B:8 F:23 105.0 0.677 -79.1 121.0 44.0 0.284 0.393 C:P00766:0.019
A:P00766:0.387
HOH
3.112
N
O
7jrx 2 P00766 83.21 3e-76 X-RAY
2021-07-21 VAL B:8 B:23 107.0 0.69 -62.4 125.9 48.0 0.31 0.38 C:P00766:0.039
A:P00766:0.374
HOH
3.069
N
O
VAL F:8 b:23 105.0 0.677 -65.6 126.1 NA NA NA
8gch 2 P00766 83.21 3e-76 X-RAY
1992-04-15 VAL B:8 F:23 106.0 0.684 -67.9 131.8 49.0 0.316 0.368 C:P00766:0.045
A:P00766:0.355
HOH
3.151
N
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p17538-f1 1 P17538 100.0 0.0 VAL A:41 A:41 46.0 0.297 -68.7 130.8
af-q6gpi1-f1 1 Q6GPI1 95.82 0.0 VAL A:41 A:41 47.0 0.303 -70.4 131.4