Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 75257442 . G A CCDS32490.1:NM_001906.4:c.412Gcc>Acc_NP_001897.4:p.138A>T Homo sapiens chymotrypsinogen B1 (CTRB1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1acb 1 P00766 81.63 3e-148 X-RAY
 1993-10-31 ALA A:120 E:120 9.0 0.078 -92.5 144.5 9.0 0.078 0.0 HOH
 3.254
 O
 O
1cgi 1 P00766 81.63 3e-148 X-RAY
 1993-10-31 ALA A:120 E:120 7.0 0.061 -116.3 163.7 7.0 0.061 0.0 HOH
 3.195
 N
 O
1cgj 1 P00766 81.63 3e-148 X-RAY
 1993-10-31 ALA A:120 E:120 8.0 0.07 -120.7 162.9 8.0 0.07 0.0 HOH
 3.879
 N
 O
1chg 1 P00766 81.63 3e-148 X-RAY
 1976-11-22 ALA A:120 A:120 5.0 0.043 -112.3 141.9 5.0 0.043 0.0
1ex3 1 P00766 81.63 3e-148 X-RAY
 2000-05-17 ALA A:120 A:120 8.0 0.07 -116.7 159.0 8.0 0.07 0.0 HOH
 4.740
 CB
 O
1gcd 1 P00766 81.63 3e-148 X-RAY
 1994-06-22 ALA A:120 A:120 12.0 0.104 -94.5 149.1 12.0 0.104 0.0 HOH
 2.635
 O
 O
1gl0 1 P00766 81.63 3e-148 X-RAY
 2001-11-28 ALA A:120 E:120 8.0 0.07 -98.7 151.7 8.0 0.07 0.0 CD
HOH
 6.374
6.175
 CB
CB
 CD
O
1gl1 1 P00766 81.63 3e-148 X-RAY
 2001-11-28 ALA A:120 A:120 10.0 0.087 -98.4 151.8 10.0 0.087 0.0 HOH
 2.834
 O
 O
ALA B:120 B:120 10.0 0.087 -99.5 155.9 NA NA NA
ALA C:120 C:120 8.0 0.07 -102.3 155.7 NA NA NA
1k2i 1 P00766 81.63 3e-148 X-RAY
 2001-12-05 ALA A:120 1:120 10.0 0.087 -98.7 152.1 10.0 0.087 0.0 HOH
 2.869
 O
 O
1oxg 1 P00766 81.63 3e-148 X-RAY
 2004-05-18 ALA A:120 A:120 9.0 0.078 -98.2 153.6 9.0 0.078 0.0 HOH
 2.833
 O
 O
1p2m 1 P00766 81.63 3e-148 X-RAY
 2004-04-20 ALA A:120 A:120 7.0 0.061 -97.7 155.0 7.0 0.061 0.0 HOH
 2.733
 O
 O
ALA C:120 C:120 6.0 0.052 -94.6 156.9 NA NA NA
1p2n 1 P00766 81.63 3e-148 X-RAY
 2004-04-20 ALA A:120 A:120 8.0 0.07 -96.9 154.8 8.0 0.07 0.0 HOH
 2.710
 O
 O
ALA C:120 C:120 7.0 0.061 -94.6 155.2 NA NA NA
1p2o 1 P00766 81.63 3e-148 X-RAY
 2004-04-20 ALA A:120 A:120 7.0 0.061 -98.1 157.1 7.0 0.061 0.0 HOH
 2.664
 O
 O
ALA C:120 C:120 6.0 0.052 -97.6 158.4 NA NA NA
1p2q 1 P00766 81.63 3e-148 X-RAY
 2004-04-20 ALA A:120 A:120 8.0 0.07 -99.5 155.0 8.0 0.07 0.0 HOH
 2.666
 O
 O
ALA C:120 C:120 6.0 0.052 -97.8 156.1 NA NA NA
1t7c 1 P00766 81.63 3e-148 X-RAY
 2005-03-08 ALA A:120 A:120 8.0 0.07 -97.4 154.6 8.0 0.07 0.0 HOH
 2.759
 O
 O
ALA C:120 C:120 5.0 0.043 -99.2 156.2 NA NA NA
1t8l 1 P00766 81.63 3e-148 X-RAY
 2005-03-08 ALA A:120 A:120 8.0 0.07 -97.7 154.1 8.0 0.07 0.0 HOH
 2.631
 O
 O
ALA C:120 C:120 7.0 0.061 -95.7 153.9 NA NA NA
1t8m 1 P00766 81.63 3e-148 X-RAY
 2005-03-08 ALA A:120 A:120 8.0 0.07 -96.9 154.8 8.0 0.07 0.0 HOH
 2.695
 O
 O
ALA C:120 C:120 7.0 0.061 -94.5 155.7 NA NA NA
1t8n 1 P00766 81.63 3e-148 X-RAY
 2005-03-08 ALA A:120 A:120 8.0 0.07 -98.7 153.9 8.0 0.07 0.0 HOH
 2.678
 O
 O
ALA C:120 C:120 5.0 0.043 -97.9 154.9 NA NA NA
1t8o 1 P00766 81.63 3e-148 X-RAY
 2005-03-08 ALA A:120 A:120 8.0 0.07 -98.4 154.8 8.0 0.07 0.0 HOH
 2.709
 O
 O
ALA C:120 C:120 7.0 0.061 -94.1 156.7 NA NA NA
2cga 1 P00766 81.63 3e-148 X-RAY
 1987-04-16 ALA A:120 A:120 9.0 0.078 -98.4 148.0 7.0 0.061 0.017 B:P00766:0.017
 HOH
 2.658
 O
 O
ALA B:120 B:120 10.0 0.087 -89.5 156.7 10.0 0.087 0.0 HOH
 2.617
 O
 O
2y6t 1 P00766 81.63 3e-148 X-RAY
 2011-04-20 ALA A:120 A:120 8.0 0.07 -123.5 143.6 8.0 0.07 0.0 HOH
 4.893
 O
 O
ALA B:120 B:120 8.0 0.07 -100.2 152.0 8.0 0.07 0.0
ALA C:120 C:120 8.0 0.07 -100.5 152.2 NA NA NA
ALA D:120 D:120 10.0 0.087 -100.1 147.0 NA NA NA
3t62 1 P00766 81.63 3e-148 X-RAY
 2012-08-01 ALA A:120 A:120 10.0 0.087 -97.8 148.1 10.0 0.087 0.0 HOH
 2.924
 O
 O
ALA C:120 B:120 10.0 0.087 -94.6 143.7 NA NA NA
ALA E:120 C:120 8.0 0.07 -94.4 146.2 NA NA NA
4q2k 1 P00766 81.63 3e-148 X-RAY
 2014-07-23 ALA A:120 A:120 10.0 0.087 -108.7 145.2 10.0 0.087 0.0 HOH
 2.808
 N
 O
ALA B:120 B:120 11.0 0.096 -101.8 146.6 NA NA NA
ALA C:120 C:120 11.0 0.096 -99.8 146.3 NA NA NA
ALA D:120 D:120 8.0 0.07 -104.4 151.9 8.0 0.07 0.0 HOH
 2.780
 O
 O
5j4q 1 P00766 81.63 3e-148 X-RAY
 2017-04-12 ALA A:120 A:120 9.0 0.078 -105.3 141.9 9.0 0.078 0.0 HOH
 2.903
 O
 O
5j4s 1 P00766 81.63 3e-148 X-RAY
 2017-04-12 ALA A:120 A:120 9.0 0.078 -101.8 147.4 9.0 0.078 0.0 HOH
 2.081
 H
 O
7kty 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 ALA A:120 A:120 11.0 0.096 -97.8 147.5 11.0 0.096 0.0 HOH
 2.966
 O
 O
7ktz 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 ALA A:120 A:120 9.0 0.078 -100.8 144.8 9.0 0.078 0.0 HOH
 2.839
 O
 O
7ku0 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 ALA A:120 A:120 9.0 0.078 -98.1 144.8 9.0 0.078 0.0 HOH
 2.864
 O
 O
7ku1 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 ALA A:120 A:120 10.0 0.087 -95.4 142.4 10.0 0.087 0.0 HOH
 6.273
 N
 O
7ku2 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 ALA A:120 A:120 10.0 0.087 -98.9 145.4 10.0 0.087 0.0 HOH
 4.180
 CB
 O
7ku3 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 ALA A:120 A:120 10.0 0.087 -99.2 145.8 10.0 0.087 0.0 HOH
 2.784
 O
 O
1dlk 2 P00766 80.87 2e-137 X-RAY
 2000-05-03 ALA B:105 B:120 36.0 0.313 -89.8 157.9 10.0 0.087 0.226 A:P00766:0.226
 HOH
 2.901
 N
 O
ALA D:105 D:120 34.0 0.296 -98.2 150.9 NA NA NA
1kdq 1 P07338 89.31 3e-84 X-RAY
 2003-06-10 ALA A:105 A:120 28.0 0.243 -109.7 162.0 28.0 0.243 0.0 HOH
 7.456
 N
 O
2jet 2 P07338 89.84 5e-83 X-RAY
 2007-09-18 ALA B:102 B:120 34.0 0.296 -94.0 166.5 7.0 0.061 0.235 A:P07338:0.235
 HOH
 2.744
 O
 O
1ab9 2 P00766 83.21 3e-76 X-RAY
 1997-08-20 ALA B:105 B:120 35.0 0.304 -99.1 150.6 10.0 0.087 0.217 A:P00766:0.217
 HOH
 2.856
 O
 O
1afq 2 P00766 83.21 3e-76 X-RAY
 1997-09-17 ALA B:105 B:120 35.0 0.304 -99.9 149.5 10.0 0.087 0.217 A:P00766:0.217
 0FG
HOH
 6.020
3.041
 CB
O
 N
O
1ca0 2 P00766 83.21 3e-76 X-RAY
 1997-07-23 ALA B:105 B:120 34.0 0.296 -99.8 151.1 9.0 0.078 0.218 A:P00766:0.217
 HOH
 2.603
 O
 O
ALA F:105 G:120 33.0 0.287 -99.0 160.0 NA NA NA
1cbw 2 P00766 83.21 3e-76 X-RAY
 1997-07-23 ALA B:105 B:120 31.0 0.27 -142.1 147.9 9.0 0.078 0.192 A:P00767:0.191
 HOH
 3.916
 CB
 O
ALA F:105 G:120 30.0 0.261 -108.7 158.5 NA NA NA
1cho 2 P00766 83.21 3e-76 X-RAY
 1988-07-16 ALA B:105 F:120 36.0 0.313 -91.7 157.8 9.0 0.078 0.235 A:P00766:0.235
 HOH
 2.803
 O
 O
1gct 2 P00766 83.21 3e-76 X-RAY
 1991-10-15 ALA B:105 B:120 37.0 0.322 -100.1 150.9 11.0 0.096 0.226 A:P00766:0.226
 HOH
 2.940
 N
 O
1gg6 2 P00766 83.21 3e-76 X-RAY
 2000-09-20 ALA B:105 B:120 36.0 0.313 -96.1 148.7 11.0 0.096 0.217 A:P00766:0.217
 EDO
EDO
HOH
 9.073
6.508
2.824
 O
CB
O
 C1
C2
O
1ggd 2 P00766 83.21 3e-76 X-RAY
 2000-09-20 ALA B:105 B:120 35.0 0.304 -98.9 151.6 9.0 0.078 0.226 A:P00766:0.226
 HOH
 2.761
 O
 O
1gha 2 P00766 83.21 3e-76 X-RAY
 1994-06-22 ALA B:105 F:120 38.0 0.33 -94.6 147.8 11.0 0.096 0.234 A:P00766:0.235
 HOH
 3.217
 N
 O
1ghb 2 P00766 83.21 3e-76 X-RAY
 1994-06-22 ALA B:105 F:120 39.0 0.339 -100.5 141.6 14.0 0.122 0.217 A:P00766:0.217
 HEX
HEX
HOH
 3.111
7.570
2.918
 O
CB
N
 C1
C6
O
1gmc 2 P00766 83.21 3e-76 X-RAY
 1993-10-31 ALA B:105 F:120 37.0 0.322 -105.7 145.3 11.0 0.096 0.226 A:P00766:0.226
 HOH
 3.037
 N
 O
1gmd 2 P00766 83.21 3e-76 X-RAY
 1993-10-31 ALA B:105 F:120 35.0 0.304 -98.5 151.9 9.0 0.078 0.226 A:P00766:0.226
 HEX
HEX
HEX
HOH
 9.060
8.040
5.356
3.102
 C
N
O
N
 C6
C6
C1
O
1gmh 2 P00766 83.21 3e-76 X-RAY
 1994-09-30 ALA B:105 F:120 35.0 0.304 -94.3 150.4 10.0 0.087 0.217 A:P00766:0.217
 HOH
 2.943
 N
 O
1hja 2 P00766 83.21 3e-76 X-RAY
 1998-01-14 ALA B:105 B:120 36.0 0.313 -86.5 156.0 11.0 0.096 0.217 A:P00766:0.217
 HOH
 4.516
 O
 O
1mtn 2 P00766 83.21 3e-76 X-RAY
 1996-08-17 ALA B:105 B:120 33.0 0.287 -111.8 155.1 10.0 0.087 0.2 A:P00766:0.2
 HOH
 7.852
 N
 O
ALA F:105 F:120 31.0 0.27 -94.1 154.9 NA NA NA
1n8o 2 P00766 83.21 3e-76 X-RAY
 2002-12-18 ALA B:105 B:120 35.0 0.304 -104.6 151.8 8.0 0.07 0.234 A:P00766:0.235
 HOH
 2.833
 O
 O
1vgc 2 P00766 83.21 3e-76 X-RAY
 1997-11-12 ALA B:105 B:120 37.0 0.322 -97.2 148.8 11.0 0.096 0.226 A:P00766:0.226
 HOH
 2.869
 O
 O
1yph 2 P00766 83.21 3e-76 X-RAY
 2006-02-14 ALA B:105 C:120 38.0 0.33 -99.3 151.5 11.0 0.096 0.234 A:P00766:0.235
 HOH
 2.762
 O
 O
ALA E:105 D:120 37.0 0.322 -98.2 152.3 10.0 0.087 0.235 D:P00766:0.235
 HOH
 2.807
 O
 O
2cha 2 P00766 83.21 3e-76 X-RAY
 1977-01-18 ALA B:105 B:120 37.0 0.322 -108.5 147.9 13.0 0.113 0.209 A:P00766:0.209
 HOH
 3.802
 N
 O
ALA E:105 F:120 35.0 0.304 -108.5 147.9 12.0 0.104 0.2 D:P00766:0.2
2gch 2 P00766 83.21 3e-76 X-RAY
 1980-07-09 ALA B:105 F:120 35.0 0.304 -109.6 147.5 11.0 0.096 0.208 A:P00766:0.209
 HOH
 2.808
 O
 O
2gct 2 P00766 83.21 3e-76 X-RAY
 1991-10-15 ALA B:105 B:120 37.0 0.322 -95.1 151.6 10.0 0.087 0.235 A:P00766:0.235
 HOH
 2.950
 N
 O
2gmt 2 P00766 83.21 3e-76 X-RAY
 1994-11-01 ALA B:105 B:120 36.0 0.313 -98.5 147.2 11.0 0.096 0.217 A:P00766:0.217
 HOH
 2.760
 N
 O
2p8o 2 P00766 83.21 3e-76 X-RAY
 2007-05-08 ALA B:105 B:120 35.0 0.304 -97.8 149.3 10.0 0.087 0.217 A:P00766:0.217
 HOH
 2.882
 O
 O
2vgc 2 P00766 83.21 3e-76 X-RAY
 1997-11-12 ALA B:105 B:120 39.0 0.339 -96.5 150.7 12.0 0.104 0.235 A:P00766:0.235
 HOH
 2.968
 N
 O
3bg4 2 P00766 83.21 3e-76 X-RAY
 2008-07-29 ALA B:105 B:120 35.0 0.304 -103.6 154.6 10.0 0.087 0.217 A:P00766:0.217
 HOH
 2.635
 O
 O
3gch 2 P00766 83.21 3e-76 X-RAY
 1990-10-15 ALA B:105 B:120 40.0 0.348 -90.4 150.5 16.0 0.139 0.209 A:P00766:0.209
 HOH
 2.836
 N
 O
3gct 2 P00766 83.21 3e-76 X-RAY
 1991-10-15 ALA B:105 F:120 37.0 0.322 -96.5 154.6 11.0 0.096 0.226 A:P00766:0.226
 HOH
 2.992
 O
 O
3ru4 4 P00766 83.21 3e-76 X-RAY
 2012-08-29 ALA D:105 D:120 35.0 0.304 -99.7 147.1 NA NA NA
3vgc 2 P00766 83.21 3e-76 X-RAY
 1997-11-12 ALA B:105 B:120 38.0 0.33 -98.2 148.9 12.0 0.104 0.226 A:P00766:0.226
 HOH
 2.972
 N
 O
4cha 2 P00766 83.21 3e-76 X-RAY
 1985-04-01 ALA B:105 B:120 37.0 0.322 -102.9 151.2 10.0 0.087 0.235 A:P00766:0.235
 HOH
 2.704
 O
 O
ALA E:105 F:120 35.0 0.304 -102.2 153.6 9.0 0.078 0.226 D:P00766:0.226
 HOH
 2.770
 O
 O
4gch 2 P00766 83.21 3e-76 X-RAY
 1990-10-15 ALA B:105 F:120 39.0 0.339 -101.7 144.3 12.0 0.104 0.235 A:P00766:0.235
 HOH
 2.698
 N
 O
4vgc 2 P00766 83.21 3e-76 X-RAY
 1997-11-12 ALA B:105 B:120 38.0 0.33 -97.0 149.9 14.0 0.122 0.208 A:P00766:0.209
 HOH
 3.055
 O
 O
5cha 2 P00766 83.21 3e-76 X-RAY
 1985-04-01 ALA B:105 B:120 36.0 0.313 -99.5 148.0 14.0 0.122 0.191 A:P00766:0.191
 HOH
 2.698
 O
 O
ALA E:105 F:120 34.0 0.296 -95.9 153.9 10.0 0.087 0.209 D:P00766:0.209
 HOH
 3.084
 N
 O
5gch 2 P00766 83.21 3e-76 X-RAY
 1990-10-15 ALA B:105 F:120 41.0 0.357 -95.1 148.2 15.0 0.13 0.227 A:P00766:0.226
 HOH
 2.887
 N
 O
5r42 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:105 B:120 36.0 0.313 -100.6 149.6 10.0 0.087 0.226 A:P00766:0.226
 HOH
 2.858
 O
 O
5r43 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:105 B:120 35.0 0.304 -101.6 150.6 10.0 0.087 0.217 A:P00766:0.217
 MLA
HOH
 3.957
2.812
 O
O
 O3B
O
5r44 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:105 B:120 36.0 0.313 -100.9 150.0 10.0 0.087 0.226 A:P00766:0.226
 HOH
 2.853
 O
 O
5r45 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:105 B:120 36.0 0.313 -98.8 149.8 10.0 0.087 0.226 A:P00766:0.226
 MLI
HOH
 4.063
2.824
 O
O
 O7
O
5r46 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:105 B:120 37.0 0.322 -101.5 148.4 10.0 0.087 0.235 A:P00766:0.235
 HOH
 2.846
 O
 O
5r47 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:105 B:120 36.0 0.313 -99.2 149.7 10.0 0.087 0.226 A:P00766:0.226
 MLA
MLA
HOH
 4.116
6.704
2.818
 O
CB
O
 O1A
C2
O
5r48 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:105 B:120 37.0 0.322 -101.4 149.0 10.0 0.087 0.235 A:P00766:0.235
 HOH
 2.849
 O
 O
5r49 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:105 B:120 35.0 0.304 -99.5 149.9 10.0 0.087 0.217 A:P00766:0.217
 MLI
HOH
 4.044
2.818
 O
O
 O7
O
5r4a 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:105 B:120 37.0 0.322 -101.2 148.1 11.0 0.096 0.226 A:P00766:0.226
 HOH
 2.842
 O
 O
5r4b 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:105 B:120 36.0 0.313 -101.6 147.1 11.0 0.096 0.217 A:P00766:0.217
 SO4
HOH
 5.438
2.809
 N
O
 O1
O
5r4c 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:105 B:120 38.0 0.33 -100.9 148.1 11.0 0.096 0.234 A:P00766:0.235
 HOH
 2.842
 O
 O
5r4d 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ALA B:105 B:120 36.0 0.313 -97.9 147.8 10.0 0.087 0.226 A:P00766:0.226
 HOH
 2.808
 O
 O
6cha 2 P00766 83.21 3e-76 X-RAY
 1987-04-16 ALA B:105 B:120 35.0 0.304 -102.1 156.2 14.0 0.122 0.182 A:P00766:0.183
 HOH
 2.414
 O
 O
ALA E:105 F:120 33.0 0.287 -98.1 154.8 8.0 0.07 0.217 D:P00766:0.217
 HOH
 2.446
 O
 O
6di8 2 P00766 83.21 3e-76 X-RAY
 2019-01-23 ALA B:105 B:120 34.0 0.296 -103.3 148.6 10.0 0.087 0.209 A:P00766:0.209
 HOH
 2.922
 O
 O
ALA E:105 E:120 34.0 0.296 -103.8 145.6 NA NA NA
ALA H:105 H:120 34.0 0.296 -102.8 148.4 NA NA NA
ALA K:105 K:120 35.0 0.304 -104.0 145.0 NA NA NA
6gch 2 P00766 83.21 3e-76 X-RAY
 1990-10-15 ALA B:105 F:120 38.0 0.33 -97.7 152.7 13.0 0.113 0.217 A:P00766:0.217
 HOH
 2.388
 N
 O
7gch 2 P00766 83.21 3e-76 X-RAY
 1990-10-15 ALA B:105 F:120 39.0 0.339 -97.0 152.8 15.0 0.13 0.209 A:P00766:0.209
 HOH
 3.196
 O
 O
7jrx 2 P00766 83.21 3e-76 X-RAY
 2021-07-21 ALA B:105 B:120 36.0 0.313 -101.2 148.4 9.0 0.078 0.235 A:P00766:0.235
 HOH
 2.776
 O
 O
ALA F:105 b:120 36.0 0.313 -100.2 147.8 NA NA NA
8gch 2 P00766 83.21 3e-76 X-RAY
 1992-04-15 ALA B:105 F:120 34.0 0.296 -101.2 156.4 9.0 0.078 0.218 A:P00766:0.217
 HOH
 2.822
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p17538-f1 1 P17538 100.0 0.0 ALA A:138 A:138 7.0 0.061 -83.5 148.2
af-q6gpi1-f1 1 Q6GPI1 95.82 0.0 ALA A:138 A:138 6.0 0.052 -84.4 149.4