Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 75257466 . G A CCDS32490.1:NM_001906.4:c.436Gac>Aac_NP_001897.4:p.146D>N Homo sapiens chymotrypsinogen B1 (CTRB1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1acb 1 P00766 81.63 3e-148 X-RAY
 1993-10-31 ASP A:128 E:128 51.0 0.34 -72.6 176.4 51.0 0.34 0.0 HOH
 2.492
 OD1
 O
1cgi 1 P00766 81.63 3e-148 X-RAY
 1993-10-31 ASP A:128 E:128 51.0 0.34 -49.9 141.0 51.0 0.34 0.0 HOH
 3.407
 O
 O
1cgj 1 P00766 81.63 3e-148 X-RAY
 1993-10-31 ASP A:128 E:128 49.0 0.327 -67.4 139.7 49.0 0.327 0.0 HOH
 3.526
 O
 O
1chg 1 P00766 81.63 3e-148 X-RAY
 1976-11-22 ASP A:128 A:128 59.0 0.393 -35.7 157.9 59.0 0.393 0.0
1ex3 1 P00766 81.63 3e-148 X-RAY
 2000-05-17 ASP A:128 A:128 58.0 0.387 -48.2 151.5 58.0 0.387 0.0 HOH
 3.787
 O
 O
1gcd 1 P00766 81.63 3e-148 X-RAY
 1994-06-22 ASP A:128 A:128 65.0 0.433 -55.4 145.2 65.0 0.433 0.0 HOH
 2.533
 OD1
 O
1gl0 1 P00766 81.63 3e-148 X-RAY
 2001-11-28 ASP A:128 E:128 53.0 0.353 -50.3 139.4 53.0 0.353 0.0 HOH
 3.550
 OD2
 O
1gl1 1 P00766 81.63 3e-148 X-RAY
 2001-11-28 ASP A:128 A:128 47.0 0.313 -48.1 141.9 47.0 0.313 0.0 HOH
 2.785
 O
 O
ASP B:128 B:128 36.0 0.24 -60.6 148.8 NA NA NA
ASP C:128 C:128 45.0 0.3 -56.8 149.0 NA NA NA
1k2i 1 P00766 81.63 3e-148 X-RAY
 2001-12-05 ASP A:128 1:128 53.0 0.353 -63.2 141.1 53.0 0.353 0.0 HOH
 3.087
 O
 O
1oxg 1 P00766 81.63 3e-148 X-RAY
 2004-05-18 ASP A:128 A:128 36.0 0.24 -59.3 144.7 36.0 0.24 0.0 HOH
 2.601
 O
 O
1p2m 1 P00766 81.63 3e-148 X-RAY
 2004-04-20 ASP A:128 A:128 37.0 0.247 -59.8 143.3 37.0 0.247 0.0 HOH
 2.659
 O
 O
ASP C:128 C:128 37.0 0.247 -57.9 148.5 NA NA NA
1p2n 1 P00766 81.63 3e-148 X-RAY
 2004-04-20 ASP A:128 A:128 37.0 0.247 -58.9 141.9 37.0 0.247 0.0 HOH
 2.716
 O
 O
ASP C:128 C:128 34.0 0.227 -57.8 145.1 NA NA NA
1p2o 1 P00766 81.63 3e-148 X-RAY
 2004-04-20 ASP A:128 A:128 39.0 0.26 -57.5 143.8 39.0 0.26 0.0 HOH
 4.857
 O
 O
ASP C:128 C:128 40.0 0.267 -54.6 146.4 NA NA NA
1p2q 1 P00766 81.63 3e-148 X-RAY
 2004-04-20 ASP A:128 A:128 38.0 0.253 -58.9 142.0 38.0 0.253 0.0 HOH
 2.579
 O
 O
ASP C:128 C:128 38.0 0.253 -59.1 143.4 NA NA NA
1t7c 1 P00766 81.63 3e-148 X-RAY
 2005-03-08 ASP A:128 A:128 38.0 0.253 -60.2 141.9 38.0 0.253 0.0 HOH
 2.626
 O
 O
ASP C:128 C:128 36.0 0.24 -55.3 143.7 NA NA NA
1t8l 1 P00766 81.63 3e-148 X-RAY
 2005-03-08 ASP A:128 A:128 38.0 0.253 -64.4 140.9 38.0 0.253 0.0 HOH
 2.688
 O
 O
ASP C:128 C:128 36.0 0.24 -57.6 143.4 NA NA NA
1t8m 1 P00766 81.63 3e-148 X-RAY
 2005-03-08 ASP A:128 A:128 40.0 0.267 -59.7 143.8 40.0 0.267 0.0 HOH
 2.690
 O
 O
ASP C:128 C:128 36.0 0.24 -52.8 143.5 NA NA NA
1t8n 1 P00766 81.63 3e-148 X-RAY
 2005-03-08 ASP A:128 A:128 38.0 0.253 -58.4 141.8 38.0 0.253 0.0 HOH
 2.584
 O
 O
ASP C:128 C:128 37.0 0.247 -55.2 143.6 NA NA NA
1t8o 1 P00766 81.63 3e-148 X-RAY
 2005-03-08 ASP A:128 A:128 39.0 0.26 -58.6 142.7 39.0 0.26 0.0 HOH
 2.696
 O
 O
ASP C:128 C:128 37.0 0.247 -57.4 145.7 NA NA NA
2cga 1 P00766 81.63 3e-148 X-RAY
 1987-04-16 ASP A:128 A:128 37.0 0.247 -63.5 132.2 37.0 0.247 0.0 HOH
 2.753
 O
 O
ASP B:128 B:128 44.0 0.293 -62.9 131.2 44.0 0.293 0.0 HOH
 4.668
 O
 O
2y6t 1 P00766 81.63 3e-148 X-RAY
 2011-04-20 ASP A:128 A:128 43.0 0.287 -63.5 158.6 43.0 0.287 0.0
ASP B:128 B:128 31.0 0.207 -67.1 148.8 31.0 0.207 0.0 HOH
 6.273
 OD1
 O
ASP C:128 C:128 28.0 0.187 -77.0 148.2 NA NA NA
ASP D:128 D:128 66.0 0.44 -61.2 130.7 NA NA NA
3t62 1 P00766 81.63 3e-148 X-RAY
 2012-08-01 ASP A:128 A:128 45.0 0.3 -65.6 143.7 45.0 0.3 0.0 HOH
 2.962
 OD1
 O
ASP C:128 B:128 53.0 0.353 -65.8 144.3 NA NA NA
ASP E:128 C:128 51.0 0.34 -61.1 138.5 NA NA NA
4q2k 1 P00766 81.63 3e-148 X-RAY
 2014-07-23 ASP A:128 A:128 52.0 0.347 -59.2 136.8 52.0 0.347 0.0 HOH
 3.000
 O
 O
ASP B:128 B:128 28.0 0.187 -58.8 141.5 NA NA NA
ASP C:128 C:128 71.0 0.473 -47.6 126.4 NA NA NA
ASP D:128 D:128 38.0 0.253 -58.7 142.9 38.0 0.253 0.0 HOH
 2.769
 O
 O
5j4q 1 P00766 81.63 3e-148 X-RAY
 2017-04-12 ASP A:128 A:128 49.0 0.327 -55.3 145.1 49.0 0.327 0.0 HOH
 6.315
 O
 O
5j4s 1 P00766 81.63 3e-148 X-RAY
 2017-04-12 ASP A:128 A:128 36.0 0.24 -60.4 143.3 36.0 0.24 0.0 HOH
 2.713
 OD1
 O
7kty 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 ASP A:128 A:128 70.0 0.467 -67.1 147.6 70.0 0.467 0.0 HOH
 2.739
 O
 O
7ktz 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 ASP A:128 A:128 47.0 0.313 -65.2 142.6 47.0 0.313 0.0 HOH
 2.523
 OD2
 O
7ku0 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 ASP A:128 A:128 68.0 0.453 -63.1 142.4 68.0 0.453 0.0 HOH
 2.686
 O
 O
7ku1 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 ASP A:128 A:128 39.0 0.26 -66.1 152.0 39.0 0.26 0.0 HOH
 4.945
 OD2
 O
7ku2 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 ASP A:128 A:128 42.0 0.28 -65.0 144.6 42.0 0.28 0.0 HOH
 2.517
 O
 O
7ku3 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 ASP A:128 A:128 69.0 0.46 -66.2 143.8 69.0 0.46 0.0 HOH
 2.557
 O
 O
1dlk 2 P00766 80.87 2e-137 X-RAY
 2000-05-03 ASP B:113 B:128 33.0 0.22 -56.6 159.7 33.0 0.22 0.0 HOH
 2.568
 OD1
 O
ASP D:113 D:128 49.0 0.327 -61.0 143.8 NA NA NA
1kdq 1 P07338 89.31 3e-84 X-RAY
 2003-06-10 ASP A:113 A:128 81.0 0.54 -90.0 140.8 38.0 0.253 0.287 B:P07338:0.287
 HOH
 7.099
 OD2
 O
2jet 2 P07338 89.84 5e-83 X-RAY
 2007-09-18 ASP B:110 B:128 85.0 0.567 -68.4 154.8 39.0 0.26 0.307 C:P07338:0.307
 HOH
 3.847
 O
 O
1ab9 2 P00766 83.21 3e-76 X-RAY
 1997-08-20 ASP B:113 B:128 80.0 0.533 -58.9 140.6 52.0 0.347 0.186 C:P00766:0.187
 HOH
 2.666
 O
 O
1afq 2 P00766 83.21 3e-76 X-RAY
 1997-09-17 ASP B:113 B:128 81.0 0.54 -64.6 137.2 58.0 0.387 0.153 C:P00766:0.153
 0FG
HOH
 6.645
2.836
 OD2
O
 CD11
O
1ca0 2 P00766 83.21 3e-76 X-RAY
 1997-07-23 ASP B:113 B:128 82.0 0.547 -86.3 142.4 45.0 0.3 0.247 C:P00766:0.247
 HOH
 3.026
 O
 O
ASP F:113 G:128 81.0 0.54 -53.3 139.6 NA NA NA
1cbw 2 P00766 83.21 3e-76 X-RAY
 1997-07-23 ASP B:113 B:128 87.0 0.58 -62.8 149.6 42.0 0.28 0.3 C:P00766:0.3
 HOH
 5.432
 O
 O
ASP F:113 G:128 84.0 0.56 -73.5 141.3 NA NA NA
1cho 2 P00766 83.21 3e-76 X-RAY
 1988-07-16 ASP B:113 F:128 94.0 0.627 -68.8 150.7 52.0 0.347 0.28 C:P00766:0.28
 HOH
 2.573
 CG
 O
1gct 2 P00766 83.21 3e-76 X-RAY
 1991-10-15 ASP B:113 B:128 81.0 0.54 -66.7 140.0 49.0 0.327 0.213 C:P00766:0.213
 HOH
 2.664
 O
 O
1gg6 2 P00766 83.21 3e-76 X-RAY
 2000-09-20 ASP B:113 B:128 78.0 0.52 -66.1 139.5 68.0 0.453 0.067 C:P00766:0.067
 EDO
SO4
HOH
 6.813
6.901
2.688
 OD2
O
OD2
 O2
O1
O
1ggd 2 P00766 83.21 3e-76 X-RAY
 2000-09-20 ASP B:113 B:128 83.0 0.553 -66.8 145.0 65.0 0.433 0.12 C:P00766:0.12
 HOH
 2.863
 O
 O
1gha 2 P00766 83.21 3e-76 X-RAY
 1994-06-22 ASP B:113 F:128 79.0 0.527 -64.3 148.1 48.0 0.32 0.207 C:P00766:0.207
 HOH
 2.770
 O
 O
1ghb 2 P00766 83.21 3e-76 X-RAY
 1994-06-22 ASP B:113 F:128 72.0 0.48 -53.7 141.6 34.0 0.227 0.253 C:P00766:0.253
 HOH
 3.878
 OD1
 O
1gmc 2 P00766 83.21 3e-76 X-RAY
 1993-10-31 ASP B:113 F:128 80.0 0.533 -55.1 137.2 49.0 0.327 0.206 C:P00766:0.207
 HOH
 4.540
 O
 O
1gmd 2 P00766 83.21 3e-76 X-RAY
 1993-10-31 ASP B:113 F:128 74.0 0.493 -57.2 129.5 43.0 0.287 0.206 C:P00766:0.207
 HOH
 4.002
 O
 O
1gmh 2 P00766 83.21 3e-76 X-RAY
 1994-09-30 ASP B:113 F:128 78.0 0.52 -60.9 131.8 53.0 0.353 0.167 C:P00766:0.167
 HOH
 4.572
 O
 O
1hja 2 P00766 83.21 3e-76 X-RAY
 1998-01-14 ASP B:113 B:128 83.0 0.553 -57.0 139.9 44.0 0.293 0.26 C:P00766:0.26
 HOH
 3.021
 OD1
 O
1mtn 2 P00766 83.21 3e-76 X-RAY
 1996-08-17 ASP B:113 B:128 79.0 0.527 -67.6 141.7 38.0 0.253 0.274 C:P00766:0.273
 HOH
 2.788
 O
 O
ASP F:113 F:128 83.0 0.553 -60.4 161.0 NA NA NA
1n8o 2 P00766 83.21 3e-76 X-RAY
 2002-12-18 ASP B:113 B:128 80.0 0.533 -71.8 141.8 48.0 0.32 0.213 C:P00766:0.213
 HOH
 2.663
 O
 O
1vgc 2 P00766 83.21 3e-76 X-RAY
 1997-11-12 ASP B:113 B:128 82.0 0.547 -71.2 144.9 52.0 0.347 0.2 C:P00766:0.2
 HOH
 2.734
 O
 O
1yph 2 P00766 83.21 3e-76 X-RAY
 2006-02-14 ASP B:113 C:128 85.0 0.567 -72.6 147.6 51.0 0.34 0.227 C:P00766:0.227
 HOH
 2.739
 O
 O
ASP E:113 D:128 84.0 0.56 -69.4 149.7 47.0 0.313 0.247 F:P00766:0.247
 HOH
 2.696
 O
 O
2cha 2 P00766 83.21 3e-76 X-RAY
 1977-01-18 ASP B:113 B:128 70.0 0.467 -82.6 151.9 38.0 0.253 0.214 C:P00766:0.213
 HOH
 6.354
 O
 O
ASP E:113 F:128 69.0 0.46 -82.6 151.9 37.0 0.247 0.213 F:P00766:0.213
2gch 2 P00766 83.21 3e-76 X-RAY
 1980-07-09 ASP B:113 F:128 80.0 0.533 -60.8 139.2 47.0 0.313 0.22 C:P00766:0.22
 HOH
 2.700
 O
 O
2gct 2 P00766 83.21 3e-76 X-RAY
 1991-10-15 ASP B:113 B:128 79.0 0.527 -65.9 143.1 44.0 0.293 0.234 C:P00766:0.233
 HOH
 3.088
 O
 O
2gmt 2 P00766 83.21 3e-76 X-RAY
 1994-11-01 ASP B:113 B:128 79.0 0.527 -68.1 142.3 53.0 0.353 0.174 C:P00766:0.173
 HOH
 2.339
 OD2
 O
2p8o 2 P00766 83.21 3e-76 X-RAY
 2007-05-08 ASP B:113 B:128 79.0 0.527 -65.1 149.2 68.0 0.453 0.074 C:P00766:0.073
 HOH
 2.752
 O
 O
2vgc 2 P00766 83.21 3e-76 X-RAY
 1997-11-12 ASP B:113 B:128 83.0 0.553 -69.8 136.1 53.0 0.353 0.2 C:P00766:0.2
 HOH
 3.315
 O
 O
3bg4 2 P00766 83.21 3e-76 X-RAY
 2008-07-29 ASP B:113 B:128 85.0 0.567 -66.2 142.5 33.0 0.22 0.347 C:P00766:0.347
 HOH
 2.532
 O
 O
3gch 2 P00766 83.21 3e-76 X-RAY
 1990-10-15 ASP B:113 B:128 71.0 0.473 -36.4 131.7 40.0 0.267 0.206 C:P00766:0.207
 HOH
 2.898
 OD1
 O
3gct 2 P00766 83.21 3e-76 X-RAY
 1991-10-15 ASP B:113 F:128 83.0 0.553 -63.1 138.4 47.0 0.313 0.24 C:P00766:0.24
 HOH
 2.738
 O
 O
3ru4 4 P00766 83.21 3e-76 X-RAY
 2012-08-29 ASP D:113 D:128 77.0 0.513 -62.6 138.7 NA NA NA
3vgc 2 P00766 83.21 3e-76 X-RAY
 1997-11-12 ASP B:113 B:128 83.0 0.553 -68.3 140.4 53.0 0.353 0.2 C:P00766:0.2
 HOH
 3.004
 O
 O
4cha 2 P00766 83.21 3e-76 X-RAY
 1985-04-01 ASP B:113 B:128 75.0 0.5 -81.6 156.9 32.0 0.213 0.287 C:P00766:0.287
 HOH
 4.646
 O
 O
ASP E:113 F:128 78.0 0.52 -80.0 157.3 42.0 0.28 0.24 F:P00766:0.24
 HOH
 4.739
 O
 O
4gch 2 P00766 83.21 3e-76 X-RAY
 1990-10-15 ASP B:113 F:128 78.0 0.52 -45.3 131.2 46.0 0.307 0.213 C:P00766:0.213
 HOH
 3.232
 OD1
 O
4vgc 2 P00766 83.21 3e-76 X-RAY
 1997-11-12 ASP B:113 B:128 83.0 0.553 -75.3 140.9 51.0 0.34 0.213 C:P00766:0.213
 HOH
 2.890
 O
 O
5cha 2 P00766 83.21 3e-76 X-RAY
 1985-04-01 ASP B:113 B:128 78.0 0.52 -72.3 150.2 30.0 0.2 0.32 C:P00766:0.32
 HOH
 2.235
 OD2
 O
ASP E:113 F:128 71.0 0.473 -73.1 154.7 35.0 0.233 0.24 F:P00766:0.24
 HOH
 2.650
 O
 O
5gch 2 P00766 83.21 3e-76 X-RAY
 1990-10-15 ASP B:113 F:128 72.0 0.48 -43.8 140.7 37.0 0.247 0.233 C:P00766:0.233
 HOH
 3.297
 OD1
 O
5r42 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ASP B:113 B:128 82.0 0.547 -66.4 146.9 50.0 0.333 0.214 C:P00766:0.213
 HOH
 2.902
 O
 O
5r43 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ASP B:113 B:128 79.0 0.527 -67.6 147.1 68.0 0.453 0.074 C:P00766:0.073
 HOH
 2.620
 OD2
 O
5r44 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ASP B:113 B:128 81.0 0.54 -65.2 148.7 49.0 0.327 0.213 C:P00766:0.213
 HOH
 2.810
 OD1
 O
5r45 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ASP B:113 B:128 81.0 0.54 -64.8 147.1 47.0 0.313 0.227 C:P00766:0.227
 HOH
 2.797
 OD1
 O
5r46 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ASP B:113 B:128 83.0 0.553 -66.6 145.7 48.0 0.32 0.233 C:P00766:0.233
 HOH
 2.888
 O
 O
5r47 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ASP B:113 B:128 80.0 0.533 -68.4 148.6 54.0 0.36 0.173 C:P00766:0.173
 HOH
 2.547
 OD2
 O
5r48 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ASP B:113 B:128 83.0 0.553 -65.6 145.4 47.0 0.313 0.24 C:P00766:0.24
 HOH
 2.753
 O
 O
5r49 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ASP B:113 B:128 80.0 0.533 -68.1 147.7 66.0 0.44 0.093 C:P00766:0.093
 HOH
 2.518
 OD2
 O
5r4a 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ASP B:113 B:128 83.0 0.553 -66.6 145.0 49.0 0.327 0.226 C:P00766:0.227
 HOH
 2.859
 O
 O
5r4b 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ASP B:113 B:128 79.0 0.527 -66.1 146.4 69.0 0.46 0.067 C:P00766:0.067
 HOH
 2.652
 OD2
 O
5r4c 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ASP B:113 B:128 84.0 0.56 -65.9 144.7 50.0 0.333 0.227 C:P00766:0.227
 HOH
 2.865
 O
 O
5r4d 2 P00766 83.21 3e-76 X-RAY
 2021-09-01 ASP B:113 B:128 78.0 0.52 -67.5 145.7 69.0 0.46 0.06 C:P00766:0.06
 HOH
 2.624
 OD2
 O
6cha 2 P00766 83.21 3e-76 X-RAY
 1987-04-16 ASP B:113 B:128 82.0 0.547 -70.9 155.7 31.0 0.207 0.34 C:P00766:0.34
 HOH
 2.140
 OD2
 O
ASP E:113 F:128 76.0 0.507 -61.2 150.2 37.0 0.247 0.26 F:P00766:0.26
 HOH
 2.511
 OD2
 O
6di8 2 P00766 83.21 3e-76 X-RAY
 2019-01-23 ASP B:113 B:128 76.0 0.507 -61.3 139.7 37.0 0.247 0.26 C:P00766:0.26
 HOH
 2.635
 OD1
 O
ASP E:113 E:128 80.0 0.533 -63.0 140.9 NA NA NA
ASP H:113 H:128 77.0 0.513 -61.3 140.3 NA NA NA
ASP K:113 K:128 79.0 0.527 -62.8 140.5 NA NA NA
6gch 2 P00766 83.21 3e-76 X-RAY
 1990-10-15 ASP B:113 F:128 88.0 0.587 -68.0 140.7 40.0 0.267 0.32 C:P00766:0.32
 HOH
 2.774
 OD2
 O
7gch 2 P00766 83.21 3e-76 X-RAY
 1990-10-15 ASP B:113 F:128 82.0 0.547 -85.8 153.1 53.0 0.353 0.194 C:P00766:0.193
 HOH
 2.831
 OD2
 O
7jrx 2 P00766 83.21 3e-76 X-RAY
 2021-07-21 ASP B:113 B:128 78.0 0.52 -63.0 141.3 33.0 0.22 0.3 C:P00766:0.3
 HOH
 2.607
 OD1
 O
ASP F:113 b:128 76.0 0.507 -64.3 142.9 NA NA NA
8gch 2 P00766 83.21 3e-76 X-RAY
 1992-04-15 ASP B:113 F:128 75.0 0.5 -67.6 136.2 59.0 0.393 0.107 C:P00766:0.107
 HOH
 2.524
 OD2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p17538-f1 1 P17538 100.0 0.0 ASP A:146 A:146 28.0 0.187 -63.7 124.9
af-q6gpi1-f1 1 Q6GPI1 95.82 0.0 ASP A:146 A:146 35.0 0.233 -65.5 129.3