Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 75257487 . C A CCDS32490.1:NM_001906.4:c.457Ctg>Atg_NP_001897.4:p.153L>M Homo sapiens chymotrypsinogen B1 (CTRB1), mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1acb 1 P00766 81.63 3e-148 X-RAY
1993-10-31 THR A:135 E:135 62.0 0.443 E -83.8 127.7 62.0 0.443 0.0 HOH
2.674
O
O
1cgi 1 P00766 81.63 3e-148 X-RAY
1993-10-31 THR A:135 E:135 64.0 0.457 E -91.8 128.5 64.0 0.457 0.0 HOH
2.751
O
O
1cgj 1 P00766 81.63 3e-148 X-RAY
1993-10-31 THR A:135 E:135 64.0 0.457 E -86.0 123.9 64.0 0.457 0.0 HOH
2.765
O
O
1chg 1 P00766 81.63 3e-148 X-RAY
1976-11-22 THR A:135 A:135 103.0 0.736 E -80.2 90.2 103.0 0.736 0.0
1ex3 1 P00766 81.63 3e-148 X-RAY
2000-05-17 THR A:135 A:135 65.0 0.464 E -80.3 124.8 65.0 0.464 0.0 HOH
5.945
CG2
O
1gcd 1 P00766 81.63 3e-148 X-RAY
1994-06-22 THR A:135 A:135 91.0 0.65 E -94.5 121.7 91.0 0.65 0.0 HOH
2.533
O
O
1gl0 1 P00766 81.63 3e-148 X-RAY
2001-11-28 THR A:135 E:135 96.0 0.686 E -84.7 127.6 96.0 0.686 0.0 HOH
2.797
O
O
1gl1 1 P00766 81.63 3e-148 X-RAY
2001-11-28 THR A:135 A:135 98.0 0.7 E -92.4 115.7 98.0 0.7 0.0 HOH
2.715
O
O
THR B:135 B:135 98.0 0.7 E -89.4 121.9 NA NA NA
THR C:135 C:135 96.0 0.686 E -88.5 118.7 NA NA NA
1k2i 1 P00766 81.63 3e-148 X-RAY
2001-12-05 THR A:135 1:135 94.0 0.671 E -94.2 124.6 94.0 0.671 0.0 HOH
2.676
O
O
1oxg 1 P00766 81.63 3e-148 X-RAY
2004-05-18 THR A:135 A:135 96.0 0.686 E -84.6 117.1 96.0 0.686 0.0 HOH
2.599
O
O
1p2m 1 P00766 81.63 3e-148 X-RAY
2004-04-20 THR A:135 A:135 97.0 0.693 E -82.6 118.5 97.0 0.693 0.0 HOH
2.723
O
O
THR C:135 C:135 99.0 0.707 E -80.6 118.4 NA NA NA
1p2n 1 P00766 81.63 3e-148 X-RAY
2004-04-20 THR A:135 A:135 98.0 0.7 E -84.0 115.6 98.0 0.7 0.0 HOH
2.770
OG1
O
THR C:135 C:135 101.0 0.721 E -81.4 117.6 NA NA NA
1p2o 1 P00766 81.63 3e-148 X-RAY
2004-04-20 THR A:135 A:135 97.0 0.693 E -82.2 109.5 97.0 0.693 0.0 HOH
7.291
CG2
O
THR C:135 C:135 100.0 0.714 E -80.5 117.8 NA NA NA
1p2q 1 P00766 81.63 3e-148 X-RAY
2004-04-20 THR A:135 A:135 98.0 0.7 E -84.7 112.9 98.0 0.7 0.0 HOH
2.844
O
O
THR C:135 C:135 102.0 0.729 E -84.5 115.7 NA NA NA
1t7c 1 P00766 81.63 3e-148 X-RAY
2005-03-08 THR A:135 A:135 97.0 0.693 E -85.9 115.8 97.0 0.693 0.0 HOH
2.894
OG1
O
THR C:135 C:135 100.0 0.714 E -83.7 118.1 NA NA NA
1t8l 1 P00766 81.63 3e-148 X-RAY
2005-03-08 THR A:135 A:135 98.0 0.7 E -84.8 113.3 98.0 0.7 0.0 HOH
2.730
OG1
O
THR C:135 C:135 101.0 0.721 E -85.2 117.1 NA NA NA
1t8m 1 P00766 81.63 3e-148 X-RAY
2005-03-08 THR A:135 A:135 95.0 0.679 E -85.2 117.9 95.0 0.679 0.0 HOH
2.816
O
O
THR C:135 C:135 100.0 0.714 E -81.6 116.0 NA NA NA
1t8n 1 P00766 81.63 3e-148 X-RAY
2005-03-08 THR A:135 A:135 97.0 0.693 E -85.1 115.8 97.0 0.693 0.0 HOH
2.837
OG1
O
THR C:135 C:135 101.0 0.721 E -81.7 119.0 NA NA NA
1t8o 1 P00766 81.63 3e-148 X-RAY
2005-03-08 THR A:135 A:135 98.0 0.7 E -84.0 119.2 98.0 0.7 0.0 HOH
2.792
O
O
THR C:135 C:135 101.0 0.721 E -81.7 117.7 NA NA NA
2cga 1 P00766 81.63 3e-148 X-RAY
1987-04-16 THR A:135 A:135 86.0 0.614 E -87.0 123.4 86.0 0.614 0.0 HOH
2.871
O
O
THR B:135 B:135 68.0 0.486 E -89.9 124.7 68.0 0.486 0.0 HOH
2.664
O
O
2y6t 1 P00766 81.63 3e-148 X-RAY
2011-04-20 THR A:135 A:135 90.0 0.643 E -85.2 126.6 90.0 0.643 0.0
THR B:135 B:135 99.0 0.707 E -69.9 119.0 99.0 0.707 0.0 HOH
6.050
CG2
O
THR C:135 C:135 98.0 0.7 E -72.7 125.9 NA NA NA
THR D:135 D:135 97.0 0.693 E -72.2 125.5 NA NA NA
3t62 1 P00766 81.63 3e-148 X-RAY
2012-08-01 THR A:135 A:135 98.0 0.7 E -82.7 116.1 98.0 0.7 0.0 HOH
2.701
O
O
THR C:135 B:135 98.0 0.7 E -84.0 119.4 NA NA NA
THR E:135 C:135 96.0 0.686 E -82.6 118.0 NA NA NA
4q2k 1 P00766 81.63 3e-148 X-RAY
2014-07-23 THR A:135 A:135 100.0 0.714 E -90.5 116.6 100.0 0.714 0.0 HOH
2.750
O
O
THR B:135 B:135 100.0 0.714 E -80.9 117.0 NA NA NA
THR C:135 C:135 90.0 0.643 E -81.3 132.0 NA NA NA
THR D:135 D:135 96.0 0.686 E -75.9 105.9 96.0 0.686 0.0 HOH
3.052
OG1
O
5j4q 1 P00766 81.63 3e-148 X-RAY
2017-04-12 THR A:135 A:135 97.0 0.693 E -86.0 119.3 97.0 0.693 0.0 HOH
4.295
CG2
O
5j4s 1 P00766 81.63 3e-148 X-RAY
2017-04-12 THR A:135 A:135 97.0 0.693 E -83.5 118.5 97.0 0.693 0.0 HOH
3.182
O
O
7kty 1 P00766 81.63 3e-148 X-RAY
2021-03-10 THR A:135 A:135 65.0 0.464 E -80.7 119.7 65.0 0.464 0.0 HOH
6.494
CG2
O
7ktz 1 P00766 81.63 3e-148 X-RAY
2021-03-10 THR A:135 A:135 62.0 0.443 E -82.6 122.5 62.0 0.443 0.0 HOH
2.632
OG1
O
7ku0 1 P00766 81.63 3e-148 X-RAY
2021-03-10 THR A:135 A:135 62.0 0.443 E -81.5 121.5 62.0 0.443 0.0 HOH
2.708
O
O
7ku1 1 P00766 81.63 3e-148 X-RAY
2021-03-10 THR A:135 A:135 69.0 0.493 E -69.2 132.5 69.0 0.493 0.0 HOH
2.862
OG1
O
7ku2 1 P00766 81.63 3e-148 X-RAY
2021-03-10 THR A:135 A:135 69.0 0.493 E -76.6 126.6 69.0 0.493 0.0
7ku3 1 P00766 81.63 3e-148 X-RAY
2021-03-10 THR A:135 A:135 63.0 0.45 E -82.1 126.2 63.0 0.45 0.0 HOH
2.687
OG1
O
1dlk 2 P00766 80.87 2e-137 X-RAY
2000-05-03 THR B:120 B:135 100.0 0.714 E -85.9 118.0 54.0 0.386 0.328 A:P00766:0.329
HOH
2.560
O
O
THR D:120 D:135 95.0 0.679 E -92.6 117.0 NA NA NA
1kdq 1 P07338 89.31 3e-84 X-RAY
2003-06-10 VAL A:120 A:135 142.0 0.916 -90.4 134.7 91.0 0.587 0.329 B:P07338:0.329
2jet 2 P07338 89.84 5e-83 X-RAY
2007-09-18 VAL B:117 B:135 147.0 0.948 -81.1 111.0 102.0 0.658 0.29 A:P07338:0.039
C:P07338:0.277
HOH
3.476
CG2
O
1ab9 2 P00766 83.21 3e-76 X-RAY
1997-08-20 THR B:120 B:135 134.0 0.957 -93.8 120.8 92.0 0.657 0.3 C:P00766:0.3
HOH
2.743
O
O
1afq 2 P00766 83.21 3e-76 X-RAY
1997-09-17 THR B:120 B:135 135.0 0.964 -93.6 121.2 94.0 0.671 0.293 C:P00766:0.293
HOH
2.731
O
O
1ca0 2 P00766 83.21 3e-76 X-RAY
1997-07-23 THR B:120 B:135 137.0 0.979 -79.0 119.6 100.0 0.714 0.265 C:P00766:0.264
HOH
5.362
CG2
O
THR F:120 G:135 133.0 0.95 -89.1 129.0 NA NA NA
1cbw 2 P00766 83.21 3e-76 X-RAY
1997-07-23 THR B:120 B:135 137.0 0.979 -87.4 107.3 93.0 0.664 0.315 C:P00766:0.314
HOH
2.661
O
O
THR F:120 G:135 135.0 0.964 -76.3 111.2 NA NA NA
1cho 2 P00766 83.21 3e-76 X-RAY
1988-07-16 THR B:120 F:135 140.0 1.0 -80.8 124.7 97.0 0.693 0.307 C:P00766:0.307
HOH
2.517
O
O
1gct 2 P00766 83.21 3e-76 X-RAY
1991-10-15 THR B:120 B:135 135.0 0.964 -94.3 118.3 94.0 0.671 0.293 C:P00766:0.293
HOH
2.576
O
O
1gg6 2 P00766 83.21 3e-76 X-RAY
2000-09-20 THR B:120 B:135 133.0 0.95 -93.0 125.5 92.0 0.657 0.293 C:P00766:0.293
SO4
HOH
9.109
2.781
N
OG1
O3
O
1ggd 2 P00766 83.21 3e-76 X-RAY
2000-09-20 THR B:120 B:135 134.0 0.957 -94.6 125.5 92.0 0.657 0.3 C:P00766:0.3
HOH
2.721
O
O
1gha 2 P00766 83.21 3e-76 X-RAY
1994-06-22 THR B:120 F:135 133.0 0.95 -80.8 130.4 91.0 0.65 0.3 C:P00766:0.3
HOH
2.678
O
O
1ghb 2 P00766 83.21 3e-76 X-RAY
1994-06-22 THR B:120 F:135 137.0 0.979 -90.0 126.8 95.0 0.679 0.3 C:P00766:0.3
HEX
HOH
9.039
2.600
CG2
OG1
C6
O
1gmc 2 P00766 83.21 3e-76 X-RAY
1993-10-31 THR B:120 F:135 136.0 0.971 -94.4 116.1 89.0 0.636 0.335 C:P00766:0.336
HOH
2.672
OG1
O
1gmd 2 P00766 83.21 3e-76 X-RAY
1993-10-31 THR B:120 F:135 138.0 0.986 -84.2 114.8 94.0 0.671 0.315 C:P00766:0.314
HEX
HEX
HOH
8.980
9.007
2.711
CG2
CG2
OG1
C1
C2
O
1gmh 2 P00766 83.21 3e-76 X-RAY
1994-09-30 THR B:120 F:135 136.0 0.971 -88.2 122.5 93.0 0.664 0.307 C:P00766:0.307
HOH
2.384
O
O
1hja 2 P00766 83.21 3e-76 X-RAY
1998-01-14 THR B:120 B:135 137.0 0.979 -84.2 118.2 98.0 0.7 0.279 C:P00766:0.279
HOH
2.659
O
O
1mtn 2 P00766 83.21 3e-76 X-RAY
1996-08-17 THR B:120 B:135 130.0 0.929 -100.4 123.9 83.0 0.593 0.336 C:P00766:0.336
HOH
7.344
O
O
THR F:120 F:135 131.0 0.936 -77.0 129.6 NA NA NA
1n8o 2 P00766 83.21 3e-76 X-RAY
2002-12-18 THR B:120 B:135 135.0 0.964 -89.0 122.5 90.0 0.643 0.321 C:P00766:0.321
HOH
2.567
O
O
1vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 THR B:120 B:135 135.0 0.964 -94.5 123.8 92.0 0.657 0.307 C:P00766:0.307
HOH
2.645
O
O
1yph 2 P00766 83.21 3e-76 X-RAY
2006-02-14 THR B:120 C:135 136.0 0.971 -86.0 117.3 93.0 0.664 0.307 C:P00766:0.307
HOH
2.653
O
O
THR E:120 D:135 136.0 0.971 -86.9 119.0 96.0 0.686 0.285 F:P00766:0.271
D:P00766:0.05
HOH
2.644
O
O
2cha 2 P00766 83.21 3e-76 X-RAY
1977-01-18 THR B:120 B:135 137.0 0.979 -90.1 116.0 103.0 0.736 0.243 C:P00766:0.243
THR E:120 F:135 137.0 0.979 -90.1 116.0 104.0 0.743 0.236 F:P00766:0.236
2gch 2 P00766 83.21 3e-76 X-RAY
1980-07-09 THR B:120 F:135 136.0 0.971 -96.2 122.2 90.0 0.643 0.328 C:P00766:0.329
HOH
2.668
O
O
2gct 2 P00766 83.21 3e-76 X-RAY
1991-10-15 THR B:120 B:135 137.0 0.979 -89.0 114.6 95.0 0.679 0.3 C:P00766:0.3
HOH
2.503
O
O
2gmt 2 P00766 83.21 3e-76 X-RAY
1994-11-01 THR B:120 B:135 133.0 0.95 -94.4 116.8 96.0 0.686 0.264 C:P00766:0.264
HOH
2.165
O
O
2p8o 2 P00766 83.21 3e-76 X-RAY
2007-05-08 THR B:120 B:135 136.0 0.971 -93.9 130.0 89.0 0.636 0.335 C:P00766:0.336
HOH
2.606
O
O
2vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 THR B:120 B:135 136.0 0.971 -92.1 119.2 92.0 0.657 0.314 C:P00766:0.314
HOH
2.631
O
O
3bg4 2 P00766 83.21 3e-76 X-RAY
2008-07-29 THR B:120 B:135 135.0 0.964 -79.6 115.9 98.0 0.7 0.264 C:P00766:0.264
HOH
3.064
O
O
3gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 THR B:120 B:135 133.0 0.95 -78.6 114.7 97.0 0.693 0.257 C:P00766:0.257
HOH
2.811
OG1
O
3gct 2 P00766 83.21 3e-76 X-RAY
1991-10-15 THR B:120 F:135 137.0 0.979 -92.1 118.9 95.0 0.679 0.3 C:P00766:0.3
HOH
2.551
O
O
3ru4 4 P00766 83.21 3e-76 X-RAY
2012-08-29 THR D:120 D:135 137.0 0.979 -84.2 121.2 NA NA NA
3vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 THR B:120 B:135 134.0 0.957 -93.1 122.7 93.0 0.664 0.293 C:P00766:0.293
HOH
2.653
O
O
4cha 2 P00766 83.21 3e-76 X-RAY
1985-04-01 THR B:120 B:135 138.0 0.986 -89.8 119.5 95.0 0.679 0.307 C:P00766:0.307
THR E:120 F:135 139.0 0.993 -93.3 123.3 102.0 0.729 0.264 F:P00766:0.264
4gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 THR B:120 F:135 135.0 0.964 -86.2 126.1 94.0 0.671 0.293 C:P00766:0.293
HOH
2.625
N
O
4vgc 2 P00766 83.21 3e-76 X-RAY
1997-11-12 THR B:120 B:135 134.0 0.957 -89.0 122.7 95.0 0.679 0.278 C:P00766:0.279
HOH
2.786
O
O
5cha 2 P00766 83.21 3e-76 X-RAY
1985-04-01 THR B:120 B:135 136.0 0.971 -89.2 109.0 98.0 0.7 0.271 C:P00766:0.271
HOH
3.014
O
O
THR E:120 F:135 140.0 1.0 -83.8 111.3 104.0 0.743 0.257 F:P00766:0.257
HOH
3.063
N
O
5gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 THR B:120 F:135 133.0 0.95 -85.0 128.3 95.0 0.679 0.271 C:P00766:0.271
HOH
2.634
O
O
5r42 2 P00766 83.21 3e-76 X-RAY
2021-09-01 THR B:120 B:135 136.0 0.971 -92.7 122.2 93.0 0.664 0.307 C:P00766:0.307
HOH
2.747
O
O
5r43 2 P00766 83.21 3e-76 X-RAY
2021-09-01 THR B:120 B:135 135.0 0.964 -93.6 121.4 91.0 0.65 0.314 C:P00766:0.314
HOH
2.720
O
O
5r44 2 P00766 83.21 3e-76 X-RAY
2021-09-01 THR B:120 B:135 135.0 0.964 -92.3 122.9 93.0 0.664 0.3 C:P00766:0.3
HOH
2.737
O
O
5r45 2 P00766 83.21 3e-76 X-RAY
2021-09-01 THR B:120 B:135 134.0 0.957 -94.9 123.3 91.0 0.65 0.307 C:P00766:0.307
HOH
2.703
O
O
5r46 2 P00766 83.21 3e-76 X-RAY
2021-09-01 THR B:120 B:135 136.0 0.971 -92.4 122.1 94.0 0.671 0.3 C:P00766:0.3
HOH
2.752
OG1
O
5r47 2 P00766 83.21 3e-76 X-RAY
2021-09-01 THR B:120 B:135 134.0 0.957 -94.9 123.9 91.0 0.65 0.307 C:P00766:0.307
HOH
2.712
O
O
5r48 2 P00766 83.21 3e-76 X-RAY
2021-09-01 THR B:120 B:135 136.0 0.971 -92.1 122.0 94.0 0.671 0.3 C:P00766:0.3
HOH
2.752
O
O
5r49 2 P00766 83.21 3e-76 X-RAY
2021-09-01 THR B:120 B:135 135.0 0.964 -95.5 123.9 91.0 0.65 0.314 C:P00766:0.314
HOH
2.727
O
O
5r4a 2 P00766 83.21 3e-76 X-RAY
2021-09-01 THR B:120 B:135 136.0 0.971 -93.3 121.7 94.0 0.671 0.3 C:P00766:0.3
HOH
2.722
O
O
5r4b 2 P00766 83.21 3e-76 X-RAY
2021-09-01 THR B:120 B:135 136.0 0.971 -93.4 123.8 93.0 0.664 0.307 C:P00766:0.307
HOH
2.608
O
O
5r4c 2 P00766 83.21 3e-76 X-RAY
2021-09-01 THR B:120 B:135 136.0 0.971 -95.1 122.7 95.0 0.679 0.292 C:P00766:0.293
HOH
2.760
OG1
O
5r4d 2 P00766 83.21 3e-76 X-RAY
2021-09-01 THR B:120 B:135 135.0 0.964 -94.7 124.4 92.0 0.657 0.307 C:P00766:0.307
HOH
2.733
OG1
O
6cha 2 P00766 83.21 3e-76 X-RAY
1987-04-16 THR B:120 B:135 135.0 0.964 -82.0 112.6 96.0 0.686 0.278 C:P00766:0.279
HOH
7.323
N
O
THR E:120 F:135 137.0 0.979 -75.1 99.8 103.0 0.736 0.243 F:P00766:0.243
HOH
1.919
O
O
6di8 2 P00766 83.21 3e-76 X-RAY
2019-01-23 THR B:120 B:135 136.0 0.971 -85.4 122.1 99.0 0.707 0.264 C:P00766:0.264
HOH
2.687
O
O
THR E:120 E:135 139.0 0.993 -84.1 122.6 NA NA NA
THR H:120 H:135 136.0 0.971 -85.3 121.8 NA NA NA
THR K:120 K:135 137.0 0.979 -83.8 124.0 NA NA NA
6gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 THR B:120 F:135 138.0 0.986 -86.8 114.5 92.0 0.657 0.329 C:P00766:0.329
HOH
2.537
O
O
7gch 2 P00766 83.21 3e-76 X-RAY
1990-10-15 THR B:120 F:135 134.0 0.957 -89.2 114.1 32.0 0.229 0.728 C:P00766:0.329
C:P00766:0.514
HOH
2.739
O
O
7jrx 2 P00766 83.21 3e-76 X-RAY
2021-07-21 THR B:120 B:135 137.0 0.979 -84.9 114.2 98.0 0.7 0.279 C:P00766:0.264
A:P00766:0.014
HOH
2.700
OG1
O
THR F:120 b:135 134.0 0.957 -83.7 113.7 NA NA NA
8gch 2 P00766 83.21 3e-76 X-RAY
1992-04-15 THR B:120 F:135 135.0 0.964 -90.6 121.7 93.0 0.664 0.3 C:P00766:0.3
A:P00766:0.007
HOH
2.690
OG1
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p17538-f1 1 P17538 100.0 0.0 LEU A:153 A:153 115.0 0.676 E -77.8 122.3
af-q6gpi1-f1 1 Q6GPI1 95.82 0.0 LEU A:153 A:153 115.0 0.676 E -77.6 121.3