Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 75258009 . G A CCDS32490.1:NM_001906.4:c.553Gaa>Aaa_NP_001897.4:p.185E>K Homo sapiens chymotrypsinogen B1 (CTRB1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1acb 1 P00766 81.63 3e-148 X-RAY
 1993-10-31 ASN A:167 E:167 67.0 0.419 H -76.3 -31.2 67.0 0.419 0.0 HOH
 4.753
 OD1
 O
1cgi 1 P00766 81.63 3e-148 X-RAY
 1993-10-31 ASN A:167 E:167 62.0 0.388 H -86.6 -14.7 62.0 0.388 0.0 HOH
 3.338
 OD1
 O
1cgj 1 P00766 81.63 3e-148 X-RAY
 1993-10-31 ASN A:167 E:167 50.0 0.312 H -91.2 -0.7 50.0 0.312 0.0 HOH
 3.505
 ND2
 O
1chg 1 P00766 81.63 3e-148 X-RAY
 1976-11-22 ASN A:167 A:167 82.0 0.512 T -72.6 -62.0 82.0 0.512 0.0
1ex3 1 P00766 81.63 3e-148 X-RAY
 2000-05-17 ASN A:167 A:167 64.0 0.4 H -51.0 -44.5 64.0 0.4 0.0 HOH
 8.651
 O
 O
1gcd 1 P00766 81.63 3e-148 X-RAY
 1994-06-22 ASN A:167 A:167 77.0 0.481 H -72.5 -34.4 77.0 0.481 0.0 HOH
 2.896
 OD1
 O
1gl0 1 P00766 81.63 3e-148 X-RAY
 2001-11-28 ASN A:167 E:167 70.0 0.438 H -69.5 -39.1 70.0 0.438 0.0 HOH
 2.902
 ND2
 O
1gl1 1 P00766 81.63 3e-148 X-RAY
 2001-11-28 ASN A:167 A:167 78.0 0.487 H -74.6 -26.5 78.0 0.487 0.0 HOH
 3.750
 CG
 O
ASN B:167 B:167 73.0 0.456 H -72.0 -30.0 NA NA NA
ASN C:167 C:167 72.0 0.45 H -67.2 -37.3 NA NA NA
1k2i 1 P00766 81.63 3e-148 X-RAY
 2001-12-05 ASN A:167 1:167 61.0 0.381 H -68.7 -30.0 61.0 0.381 0.0 HOH
 4.207
 ND2
 O
1oxg 1 P00766 81.63 3e-148 X-RAY
 2004-05-18 ASN A:167 A:167 69.0 0.431 H -73.5 -32.2 69.0 0.431 0.0 HOH
 2.715
 ND2
 O
1p2m 1 P00766 81.63 3e-148 X-RAY
 2004-04-20 ASN A:167 A:167 67.0 0.419 H -67.1 -40.4 67.0 0.419 0.0 HOH
 3.685
 CB
 O
ASN C:167 C:167 68.0 0.425 H -67.8 -39.8 NA NA NA
1p2n 1 P00766 81.63 3e-148 X-RAY
 2004-04-20 ASN A:167 A:167 78.0 0.487 H -70.2 -35.8 78.0 0.487 0.0 HOH
 2.768
 ND2
 O
ASN C:167 C:167 66.0 0.412 H -66.8 -40.9 NA NA NA
1p2o 1 P00766 81.63 3e-148 X-RAY
 2004-04-20 ASN A:167 A:167 72.0 0.45 H -68.1 -37.3 72.0 0.45 0.0 HOH
 3.834
 CB
 O
ASN C:167 C:167 67.0 0.419 H -67.2 -39.3 NA NA NA
1p2q 1 P00766 81.63 3e-148 X-RAY
 2004-04-20 ASN A:167 A:167 63.0 0.394 H -70.5 -39.7 63.0 0.394 0.0 HOH
 3.353
 ND2
 O
ASN C:167 C:167 70.0 0.438 H -69.4 -37.3 NA NA NA
1t7c 1 P00766 81.63 3e-148 X-RAY
 2005-03-08 ASN A:167 A:167 79.0 0.494 H -71.6 -34.9 79.0 0.494 0.0 HOH
 2.948
 OD1
 O
ASN C:167 C:167 69.0 0.431 H -68.0 -39.9 NA NA NA
1t8l 1 P00766 81.63 3e-148 X-RAY
 2005-03-08 ASN A:167 A:167 79.0 0.494 H -69.5 -34.3 79.0 0.494 0.0 HOH
 2.881
 ND2
 O
ASN C:167 C:167 65.0 0.406 H -67.2 -37.5 NA NA NA
1t8m 1 P00766 81.63 3e-148 X-RAY
 2005-03-08 ASN A:167 A:167 81.0 0.506 H -69.9 -34.0 81.0 0.506 0.0 HOH
 2.827
 ND2
 O
ASN C:167 C:167 65.0 0.406 H -67.0 -35.7 NA NA NA
1t8n 1 P00766 81.63 3e-148 X-RAY
 2005-03-08 ASN A:167 A:167 79.0 0.494 H -71.1 -34.7 79.0 0.494 0.0 HOH
 2.868
 OD1
 O
ASN C:167 C:167 64.0 0.4 H -67.6 -38.7 NA NA NA
1t8o 1 P00766 81.63 3e-148 X-RAY
 2005-03-08 ASN A:167 A:167 78.0 0.487 H -69.6 -35.6 78.0 0.487 0.0 HOH
 2.752
 ND2
 O
ASN C:167 C:167 70.0 0.438 H -67.7 -38.1 NA NA NA
2cga 1 P00766 81.63 3e-148 X-RAY
 1987-04-16 ASN A:167 A:167 56.0 0.35 H -72.6 -34.6 56.0 0.35 0.0 HOH
 2.832
 ND2
 O
ASN B:167 B:167 46.0 0.287 H -74.9 -36.2 46.0 0.287 0.0 HOH
 4.787
 OD1
 O
2y6t 1 P00766 81.63 3e-148 X-RAY
 2011-04-20 ASN A:167 A:167 70.0 0.438 H -73.3 -20.5 70.0 0.438 0.0 HOH
 2.784
 OD1
 O
ASN B:167 B:167 83.0 0.519 H -74.0 -34.1 83.0 0.519 0.0
ASN C:167 C:167 74.0 0.463 H -65.9 -22.3 NA NA NA
ASN D:167 D:167 97.0 0.606 H -73.3 -35.4 NA NA NA
3t62 1 P00766 81.63 3e-148 X-RAY
 2012-08-01 ASN A:167 A:167 88.0 0.55 H -66.6 -36.8 88.0 0.55 0.0 HOH
 3.273
 ND2
 O
ASN C:167 B:167 75.0 0.469 H -66.2 -39.2 NA NA NA
ASN E:167 C:167 71.0 0.444 H -67.2 -37.0 NA NA NA
4q2k 1 P00766 81.63 3e-148 X-RAY
 2014-07-23 ASN A:167 A:167 67.0 0.419 H -70.3 -41.2 67.0 0.419 0.0 HOH
 2.739
 ND2
 O
ASN B:167 B:167 101.0 0.631 H -61.4 -37.0 NA NA NA
ASN C:167 C:167 75.0 0.469 H -63.7 -38.7 NA NA NA
ASN D:167 D:167 79.0 0.494 H -64.8 -31.3 79.0 0.494 0.0 HOH
 3.730
 OD1
 O
5j4q 1 P00766 81.63 3e-148 X-RAY
 2017-04-12 ASN A:167 A:167 83.0 0.519 H -63.0 -35.5 83.0 0.519 0.0 HOH
 8.776
 N
 O
5j4s 1 P00766 81.63 3e-148 X-RAY
 2017-04-12 ASN A:167 A:167 73.0 0.456 H -68.4 -33.7 73.0 0.456 0.0 HOH
 1.917
 HD22
 O
7kty 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 ASN A:167 A:167 70.0 0.438 H -64.4 -32.9 70.0 0.438 0.0 HOH
 2.862
 ND2
 O
7ktz 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 ASN A:167 A:167 69.0 0.431 H -70.9 -30.9 69.0 0.431 0.0 HOH
 2.780
 ND2
 O
7ku0 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 ASN A:167 A:167 69.0 0.431 H -67.9 -29.7 69.0 0.431 0.0 HOH
 3.036
 ND2
 O
7ku1 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 ASN A:167 A:167 71.0 0.444 H -74.7 -31.3 71.0 0.444 0.0
7ku2 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 ASN A:167 A:167 76.0 0.475 H -66.3 -30.9 76.0 0.475 0.0 HOH
 2.986
 ND2
 O
7ku3 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 ASN A:167 A:167 71.0 0.444 H -69.1 -33.0 71.0 0.444 0.0 HOH
 2.722
 ND2
 O
1dlk 2 P00766 80.87 2e-137 X-RAY
 2000-05-03 ASN B:152 B:167 63.0 0.394 H -69.7 -34.4 63.0 0.394 0.0 HOH
 3.304
 ND2
 O
ASN D:152 D:167 57.0 0.356 H -67.3 -37.5 NA NA NA
1ab9 3 P00766 80.21 5e-51 X-RAY
 1997-08-20 ASN C:19 C:167 75.0 0.469 H -71.7 -35.5 75.0 0.469 0.0 HOH
 3.037
 ND2
 O
1ca0 3 P00766 80.21 5e-51 X-RAY
 1997-07-23 ASN C:19 C:167 75.0 0.469 H -56.7 -41.6 75.0 0.469 0.0 HOH
 2.792
 ND2
 O
ASN G:19 H:167 86.0 0.537 H -75.7 -31.2 NA NA NA
1cbw 3 P00766 80.21 5e-51 X-RAY
 1997-07-23 ASN C:19 C:167 75.0 0.469 H -65.4 -32.2 75.0 0.469 0.0 HOH
 3.792
 CB
 O
ASN G:19 H:167 90.0 0.562 H -49.2 -35.8 NA NA NA
1cho 3 P00766 80.21 5e-51 X-RAY
 1988-07-16 ASN C:19 G:167 87.0 0.544 H -70.2 -35.1 87.0 0.544 0.0 HOH
 2.591
 OD1
 O
1gct 3 P00766 80.21 5e-51 X-RAY
 1991-10-15 ASN C:19 C:167 63.0 0.394 H -69.1 -35.2 63.0 0.394 0.0 HOH
 2.787
 CB
 O
1gg6 3 P00766 80.21 5e-51 X-RAY
 2000-09-20 ASN C:19 C:167 60.0 0.375 H -68.4 -41.2 60.0 0.375 0.0 SO4
HOH
 7.987
2.630
 N
OD1
 O2
O
1ggd 3 P00766 80.21 5e-51 X-RAY
 2000-09-20 ASN C:19 C:167 72.0 0.45 H -67.2 -31.3 72.0 0.45 0.0 HOH
 2.777
 ND2
 O
1gha 3 P00766 80.21 5e-51 X-RAY
 1994-06-22 ASN C:19 G:167 58.0 0.362 H -63.3 -35.2 58.0 0.362 0.0 HOH
 3.088
 ND2
 O
1ghb 3 P00766 80.21 5e-51 X-RAY
 1994-06-22 ASN C:19 G:167 55.0 0.344 H -73.7 -29.0 55.0 0.344 0.0 HOH
 5.207
 O
 O
1gmc 3 P00766 80.21 5e-51 X-RAY
 1993-10-31 ASN C:19 G:167 62.0 0.388 H -72.8 -41.3 62.0 0.388 0.0 HOH
 6.035
 ND2
 O
1gmd 3 P00766 80.21 5e-51 X-RAY
 1993-10-31 ASN C:19 G:167 60.0 0.375 H -62.2 -41.6 60.0 0.375 0.0 HOH
 3.634
 ND2
 O
1gmh 3 P00766 80.21 5e-51 X-RAY
 1994-09-30 ASN C:19 G:167 55.0 0.344 H -72.0 -25.7 55.0 0.344 0.0 HOH
 5.739
 N
 O
1hja 3 P00766 80.21 5e-51 X-RAY
 1998-01-14 ASN C:19 C:167 80.0 0.5 H -64.9 -29.7 79.0 0.494 0.006 B:P00766:0.006
 HOH
 3.027
 ND2
 O
1mtn 3 P00766 80.21 5e-51 X-RAY
 1996-08-17 ASN C:19 C:167 83.0 0.519 H -59.4 -22.3 81.0 0.506 0.013 B:P00766:0.013
 HOH
 6.419
 OD1
 O
ASN G:19 G:167 85.0 0.531 H -61.1 -25.4 NA NA NA
1n8o 3 P00766 80.21 5e-51 X-RAY
 2002-12-18 ASN C:19 C:167 47.0 0.294 H -61.5 -35.1 47.0 0.294 0.0 HOH
 2.841
 ND2
 O
1vgc 3 P00766 80.21 5e-51 X-RAY
 1997-11-12 ASN C:19 C:167 54.0 0.338 H -72.7 -36.6 53.0 0.331 0.007 B:P00766:0.006
 HOH
 6.793
 C
 O
1yph 3 P00766 80.21 5e-51 X-RAY
 2006-02-14 ASN C:19 E:167 85.0 0.531 H -64.8 -31.8 82.0 0.512 0.019 B:P00766:0.019
 HOH
 2.770
 ND2
 O
ASN F:19 F:167 77.0 0.481 H -67.5 -38.1 77.0 0.481 0.0 HOH
 3.048
 ND2
 O
2cha 3 P00766 80.21 5e-51 X-RAY
 1977-01-18 ASN C:19 C:167 72.0 0.45 H -68.7 -23.6 72.0 0.45 0.0
ASN F:19 G:167 73.0 0.456 H -68.7 -23.6 73.0 0.456 0.0
2gch 3 P00766 80.21 5e-51 X-RAY
 1980-07-09 ASN C:19 G:167 62.0 0.388 H -67.2 -33.4 62.0 0.388 0.0 HOH
 3.700
 CB
 O
2gct 3 P00766 80.21 5e-51 X-RAY
 1991-10-15 ASN C:19 C:167 58.0 0.362 H -76.6 -30.5 58.0 0.362 0.0 HOH
 3.111
 ND2
 O
2gmt 3 P00766 80.21 5e-51 X-RAY
 1994-11-01 ASN C:19 C:167 57.0 0.356 H -71.7 -44.0 57.0 0.356 0.0 HOH
 3.159
 ND2
 O
2p8o 3 P00766 80.21 5e-51 X-RAY
 2007-05-08 ASN C:19 C:167 70.0 0.438 H -62.6 -38.7 70.0 0.438 0.0 HOH
 2.569
 ND2
 O
2vgc 3 P00766 80.21 5e-51 X-RAY
 1997-11-12 ASN C:19 C:167 54.0 0.338 H -69.2 -33.6 54.0 0.338 0.0 HOH
 6.425
 ND2
 O
3bg4 3 P00766 80.21 5e-51 X-RAY
 2008-07-29 ASN C:19 C:167 70.0 0.438 H -61.0 -49.3 70.0 0.438 0.0 HOH
 2.525
 OD1
 O
3gch 3 P00766 80.21 5e-51 X-RAY
 1990-10-15 ASN C:19 C:167 61.0 0.381 H -66.9 -20.9 61.0 0.381 0.0 HOH
 5.729
 ND2
 O
3gct 3 P00766 80.21 5e-51 X-RAY
 1991-10-15 ASN C:19 G:167 73.0 0.456 H -70.1 -30.1 73.0 0.456 0.0 HOH
 2.807
 ND2
 O
3vgc 3 P00766 80.21 5e-51 X-RAY
 1997-11-12 ASN C:19 C:167 51.0 0.319 H -64.0 -35.4 51.0 0.319 0.0 HOH
 6.522
 ND2
 O
4cha 3 P00766 80.21 5e-51 X-RAY
 1985-04-01 ASN C:19 C:167 85.0 0.531 H -59.9 -41.1 84.0 0.525 0.006 B:P00766:0.006
ASN F:19 G:167 78.0 0.487 H -63.7 -34.2 76.0 0.475 0.012 E:P00766:0.013
4gch 3 P00766 80.21 5e-51 X-RAY
 1990-10-15 ASN C:19 G:167 62.0 0.388 H -74.4 -20.7 62.0 0.388 0.0 HOH
 5.741
 ND2
 O
4vgc 3 P00766 80.21 5e-51 X-RAY
 1997-11-12 ASN C:19 C:167 49.0 0.306 H -65.7 -28.3 49.0 0.306 0.0 HOH
 6.291
 ND2
 O
5cha 3 P00766 80.21 5e-51 X-RAY
 1985-04-01 ASN C:19 C:167 63.0 0.394 H -66.1 -41.1 63.0 0.394 0.0 HOH
 3.217
 CG
 O
ASN F:19 G:167 67.0 0.419 H -69.9 -31.3 66.0 0.412 0.007 E:P00766:0.006
 HOH
 2.274
 OD1
 O
5gch 3 P00766 80.21 5e-51 X-RAY
 1990-10-15 ASN C:19 G:167 65.0 0.406 H -67.1 -20.5 65.0 0.406 0.0 HOH
 5.218
 ND2
 O
5r42 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 ASN C:19 C:167 67.0 0.419 H -71.7 -36.1 67.0 0.419 0.0 HOH
 2.867
 OD1
 O
5r43 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 ASN C:19 C:167 65.0 0.406 H -70.2 -38.3 65.0 0.406 0.0 HOH
 2.605
 ND2
 O
5r44 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 ASN C:19 C:167 50.0 0.312 H -71.4 -37.4 50.0 0.312 0.0 HOH
 4.490
 CB
 O
5r45 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 ASN C:19 C:167 67.0 0.419 H -71.4 -38.2 67.0 0.419 0.0 HOH
 2.960
 ND2
 O
5r46 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 ASN C:19 C:167 65.0 0.406 H -72.2 -35.1 65.0 0.406 0.0 HOH
 2.974
 OD1
 O
5r47 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 ASN C:19 C:167 64.0 0.4 H -70.0 -39.1 64.0 0.4 0.0 HOH
 2.807
 OD1
 O
5r48 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 ASN C:19 C:167 69.0 0.431 H -70.5 -36.1 69.0 0.431 0.0 HOH
 2.972
 OD1
 O
5r49 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 ASN C:19 C:167 64.0 0.4 H -69.4 -38.6 64.0 0.4 0.0 HOH
 2.811
 OD1
 O
5r4a 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 ASN C:19 C:167 64.0 0.4 H -73.4 -35.7 64.0 0.4 0.0 HOH
 3.869
 ND2
 O
5r4b 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 ASN C:19 C:167 64.0 0.4 H -72.4 -37.0 64.0 0.4 0.0 HOH
 2.706
 ND2
 O
5r4c 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 ASN C:19 C:167 56.0 0.35 H -73.7 -34.8 56.0 0.35 0.0 HOH
 5.448
 N
 O
5r4d 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 ASN C:19 C:167 62.0 0.388 H -71.3 -37.4 62.0 0.388 0.0 HOH
 2.571
 OD1
 O
6cha 3 P00766 80.21 5e-51 X-RAY
 1987-04-16 ASN C:19 C:167 58.0 0.362 H -70.0 -31.3 58.0 0.362 0.0 HOH
 5.661
 OD1
 O
ASN F:19 G:167 77.0 0.481 H -81.4 -28.8 77.0 0.481 0.0 HOH
 2.663
 OD1
 O
6di8 3 P00766 80.21 5e-51 X-RAY
 2019-01-23 ASN C:19 C:167 81.0 0.506 H -70.2 -32.5 80.0 0.5 0.006 B:P00766:0.006
 HOH
 3.049
 ND2
 O
ASN F:19 F:167 76.0 0.475 H -69.0 -30.0 NA NA NA
ASN I:19 I:167 54.0 0.338 H -66.0 -34.9 NA NA NA
ASN L:19 L:167 80.0 0.5 H -70.1 -30.0 NA NA NA
6gch 3 P00766 80.21 5e-51 X-RAY
 1990-10-15 ASN C:19 G:167 69.0 0.431 H -70.9 -23.2 69.0 0.431 0.0 HOH
 2.305
 ND2
 O
7gch 3 P00766 80.21 5e-51 X-RAY
 1990-10-15 ASN C:19 G:167 68.0 0.425 H -60.7 -28.1 16.0 0.1 0.325 B:P00766:0.325
 HOH
 2.869
 ND2
 O
7jrx 3 P00766 80.21 5e-51 X-RAY
 2021-07-21 ASN C:19 C:167 71.0 0.444 H -68.1 -36.5 70.0 0.438 0.006 B:P00766:0.006
 HOH
 2.979
 CB
 O
ASN G:19 c:167 99.0 0.619 H -66.0 -34.5 NA NA NA
8gch 3 P00766 80.21 5e-51 X-RAY
 1992-04-15 ASN C:19 G:167 62.0 0.388 H -69.8 -37.7 62.0 0.388 0.0 HOH
 2.887
 OD1
 O
1afq 3 P00766 80.21 6e-51 X-RAY
 1997-09-17 ASN C:18 C:167 73.0 0.456 H -68.7 -34.2 73.0 0.456 0.0 HOH
 6.568
 OD1
 O
3ru4 5 P00766 80.21 6e-51 X-RAY
 2012-08-29 ASN E:18 E:167 73.0 0.456 H -61.5 -44.2 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p17538-f1 1 P17538 100.0 0.0 GLU A:185 A:185 74.0 0.389 H -69.9 -44.5
af-q6gpi1-f1 1 Q6GPI1 95.82 0.0 GLU A:185 A:185 81.0 0.426 H -67.1 -43.4