Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 75258014 . C A CCDS32490.1:NM_001906.4:c.558tgC>tgA_NP_001897.4:p.186C>* Homo sapiens chymotrypsinogen B1 (CTRB1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1acb 1 P00766 81.63 3e-148 X-RAY
 1993-10-31 CYS A:168 E:168 0.0 0.0 H -64.4 -38.3 0.0 0.0 0.0 HOH
 4.069
 CB
 O
1cgi 1 P00766 81.63 3e-148 X-RAY
 1993-10-31 CYS A:168 E:168 0.0 0.0 H -82.2 -37.5 0.0 0.0 0.0 HOH
 6.965
 N
 O
1cgj 1 P00766 81.63 3e-148 X-RAY
 1993-10-31 CYS A:168 E:168 0.0 0.0 H -91.8 -34.1 0.0 0.0 0.0 HOH
 6.726
 N
 O
1chg 1 P00766 81.63 3e-148 X-RAY
 1976-11-22 CYS A:168 A:168 0.0 0.0 T -46.3 -48.8 0.0 0.0 0.0
1ex3 1 P00766 81.63 3e-148 X-RAY
 2000-05-17 CYS A:168 A:168 0.0 0.0 H -46.9 -45.3 0.0 0.0 0.0 HOH
 7.168
 O
 O
1gcd 1 P00766 81.63 3e-148 X-RAY
 1994-06-22 CYS A:168 A:168 0.0 0.0 H -66.7 -35.0 0.0 0.0 0.0 HOH
 4.152
 CB
 O
1gl0 1 P00766 81.63 3e-148 X-RAY
 2001-11-28 CYS A:168 E:168 0.0 0.0 H -57.4 -33.0 0.0 0.0 0.0 HOH
 4.133
 CB
 O
1gl1 1 P00766 81.63 3e-148 X-RAY
 2001-11-28 CYS A:168 A:168 0.0 0.0 H -75.7 -32.5 0.0 0.0 0.0 HOH
 4.239
 CB
 O
CYS B:168 B:168 0.0 0.0 H -69.6 -32.9 NA NA NA
CYS C:168 C:168 0.0 0.0 H -63.4 -32.7 NA NA NA
1k2i 1 P00766 81.63 3e-148 X-RAY
 2001-12-05 CYS A:168 1:168 0.0 0.0 H -68.5 -33.5 0.0 0.0 0.0 HOH
 4.319
 CB
 O
1oxg 1 P00766 81.63 3e-148 X-RAY
 2004-05-18 CYS A:168 A:168 0.0 0.0 H -66.5 -34.4 0.0 0.0 0.0 HOH
 3.747
 CB
 O
1p2m 1 P00766 81.63 3e-148 X-RAY
 2004-04-20 CYS A:168 A:168 0.0 0.0 H -65.4 -44.7 0.0 0.0 0.0 HOH
 4.348
 CB
 O
CYS C:168 C:168 0.0 0.0 H -63.4 -45.2 NA NA NA
1p2n 1 P00766 81.63 3e-148 X-RAY
 2004-04-20 CYS A:168 A:168 0.0 0.0 H -65.2 -44.6 0.0 0.0 0.0 SO4
HOH
 9.976
4.382
 O
CB
 O2
O
CYS C:168 C:168 0.0 0.0 H -63.0 -45.5 NA NA NA
1p2o 1 P00766 81.63 3e-148 X-RAY
 2004-04-20 CYS A:168 A:168 0.0 0.0 H -66.1 -43.5 0.0 0.0 0.0 HOH
 4.222
 CB
 O
CYS C:168 C:168 0.0 0.0 H -60.9 -50.7 NA NA NA
1p2q 1 P00766 81.63 3e-148 X-RAY
 2004-04-20 CYS A:168 A:168 0.0 0.0 H -63.3 -46.2 0.0 0.0 0.0 HOH
 4.369
 CB
 O
CYS C:168 C:168 0.0 0.0 H -65.4 -46.1 NA NA NA
1t7c 1 P00766 81.63 3e-148 X-RAY
 2005-03-08 CYS A:168 A:168 0.0 0.0 H -67.1 -46.6 0.0 0.0 0.0 HOH
 4.352
 CB
 O
CYS C:168 C:168 0.0 0.0 H -63.3 -49.5 NA NA NA
1t8l 1 P00766 81.63 3e-148 X-RAY
 2005-03-08 CYS A:168 A:168 0.0 0.0 H -66.3 -43.2 0.0 0.0 0.0 HOH
 4.344
 CB
 O
CYS C:168 C:168 0.0 0.0 H -66.3 -42.1 NA NA NA
1t8m 1 P00766 81.63 3e-148 X-RAY
 2005-03-08 CYS A:168 A:168 0.0 0.0 H -66.8 -46.5 0.0 0.0 0.0 HOH
 4.451
 CB
 O
CYS C:168 C:168 0.0 0.0 H -66.4 -46.3 NA NA NA
1t8n 1 P00766 81.63 3e-148 X-RAY
 2005-03-08 CYS A:168 A:168 0.0 0.0 H -67.0 -47.4 0.0 0.0 0.0 HOH
 4.388
 CB
 O
CYS C:168 C:168 0.0 0.0 H -64.7 -48.2 NA NA NA
1t8o 1 P00766 81.63 3e-148 X-RAY
 2005-03-08 CYS A:168 A:168 0.0 0.0 H -67.5 -41.8 0.0 0.0 0.0 HOH
 4.310
 CB
 O
CYS C:168 C:168 0.0 0.0 H -66.1 -45.7 NA NA NA
2cga 1 P00766 81.63 3e-148 X-RAY
 1987-04-16 CYS A:168 A:168 0.0 0.0 H -65.5 -30.4 0.0 0.0 0.0 HOH
 4.358
 CB
 O
CYS B:168 B:168 0.0 0.0 H -64.2 -29.9 0.0 0.0 0.0 HOH
 4.111
 CB
 O
2y6t 1 P00766 81.63 3e-148 X-RAY
 2011-04-20 CYS A:168 A:168 0.0 0.0 H -75.8 -29.6 0.0 0.0 0.0 HOH
 5.722
 N
 O
CYS B:168 B:168 0.0 0.0 H -71.1 -29.6 0.0 0.0 0.0
CYS C:168 C:168 0.0 0.0 H -78.4 -34.2 NA NA NA
CYS D:168 D:168 0.0 0.0 H -74.3 -30.0 NA NA NA
3t62 1 P00766 81.63 3e-148 X-RAY
 2012-08-01 CYS A:168 A:168 0.0 0.0 H -61.7 -35.2 0.0 0.0 0.0 HOH
 4.030
 CB
 O
CYS C:168 B:168 0.0 0.0 H -66.3 -37.8 NA NA NA
CYS E:168 C:168 0.0 0.0 H -68.6 -39.0 NA NA NA
4q2k 1 P00766 81.63 3e-148 X-RAY
 2014-07-23 CYS A:168 A:168 0.0 0.0 H -57.4 -38.0 0.0 0.0 0.0 HOH
 4.173
 CB
 O
CYS B:168 B:168 0.0 0.0 H -64.5 -34.7 NA NA NA
CYS C:168 C:168 0.0 0.0 H -68.4 -36.9 NA NA NA
CYS D:168 D:168 0.0 0.0 H -66.8 -47.0 0.0 0.0 0.0 HOH
 4.385
 CB
 O
5j4q 1 P00766 81.63 3e-148 X-RAY
 2017-04-12 CYS A:168 A:168 0.0 0.0 H -66.4 -33.6 0.0 0.0 0.0 HOH
 7.976
 CB
 O
5j4s 1 P00766 81.63 3e-148 X-RAY
 2017-04-12 CYS A:168 A:168 0.0 0.0 H -65.7 -34.3 0.0 0.0 0.0 HOH
 3.432
 HB2
 O
7kty 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 CYS A:168 A:168 0.0 0.0 H -65.8 -29.1 0.0 0.0 0.0 HOH
 3.979
 CB
 O
7ktz 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 CYS A:168 A:168 0.0 0.0 H -64.1 -32.1 0.0 0.0 0.0 HOH
 3.901
 CB
 O
7ku0 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 CYS A:168 A:168 0.0 0.0 H -66.7 -31.0 0.0 0.0 0.0 HOH
 3.870
 CB
 O
7ku1 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 CYS A:168 A:168 0.0 0.0 H -70.6 -32.6 0.0 0.0 0.0
7ku2 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 CYS A:168 A:168 0.0 0.0 H -68.2 -28.4 0.0 0.0 0.0 HOH
 3.974
 CB
 O
7ku3 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 CYS A:168 A:168 0.0 0.0 H -64.1 -31.9 0.0 0.0 0.0 HOH
 3.782
 CB
 O
1dlk 2 P00766 80.87 2e-137 X-RAY
 2000-05-03 CYS B:153 B:168 0.0 0.0 H -61.9 -43.5 0.0 0.0 0.0 HOH
 4.085
 CB
 O
CYS D:153 D:168 0.0 0.0 H -62.7 -34.3 NA NA NA
1ab9 3 P00766 80.21 5e-51 X-RAY
 1997-08-20 CYS C:20 C:168 0.0 0.0 H -63.6 -30.8 0.0 0.0 0.0 HOH
 4.375
 CB
 O
1ca0 3 P00766 80.21 5e-51 X-RAY
 1997-07-23 CYS C:20 C:168 0.0 0.0 H -67.4 -41.4 0.0 0.0 0.0 HOH
 4.309
 CB
 O
CYS G:20 H:168 0.0 0.0 H -67.6 -42.3 NA NA NA
1cbw 3 P00766 80.21 5e-51 X-RAY
 1997-07-23 CYS C:20 C:168 0.0 0.0 H -70.2 -35.1 0.0 0.0 0.0 HOH
 4.210
 CB
 O
CYS G:20 H:168 0.0 0.0 H -67.3 -55.1 NA NA NA
1cho 3 P00766 80.21 5e-51 X-RAY
 1988-07-16 CYS C:20 G:168 0.0 0.0 H -61.9 -34.0 0.0 0.0 0.0 HOH
 4.142
 CB
 O
1gct 3 P00766 80.21 5e-51 X-RAY
 1991-10-15 CYS C:20 C:168 0.0 0.0 H -64.3 -36.0 0.0 0.0 0.0 HOH
 4.195
 CB
 O
1gg6 3 P00766 80.21 5e-51 X-RAY
 2000-09-20 CYS C:20 C:168 0.0 0.0 H -61.4 -32.3 0.0 0.0 0.0 SO4
HOH
 7.387
4.303
 CB
CB
 O2
O
1ggd 3 P00766 80.21 5e-51 X-RAY
 2000-09-20 CYS C:20 C:168 0.0 0.0 H -69.6 -27.4 0.0 0.0 0.0 HOH
 4.254
 CB
 O
1gha 3 P00766 80.21 5e-51 X-RAY
 1994-06-22 CYS C:20 G:168 0.0 0.0 H -67.8 -36.1 0.0 0.0 0.0 HOH
 4.578
 CB
 O
1ghb 3 P00766 80.21 5e-51 X-RAY
 1994-06-22 CYS C:20 G:168 0.0 0.0 H -80.4 -26.8 0.0 0.0 0.0 ACE
TRP
HOH
 9.514
9.397
4.469
 SG
SG
CB
 CH3
OXT
O
1gmc 3 P00766 80.21 5e-51 X-RAY
 1993-10-31 CYS C:20 G:168 0.0 0.0 H -64.4 -31.0 0.0 0.0 0.0 HOH
 4.690
 CB
 O
1gmd 3 P00766 80.21 5e-51 X-RAY
 1993-10-31 CYS C:20 G:168 0.0 0.0 H -64.1 -31.2 0.0 0.0 0.0 HOH
 7.112
 N
 O
1gmh 3 P00766 80.21 5e-51 X-RAY
 1994-09-30 CYS C:20 G:168 0.0 0.0 H -77.8 -23.4 0.0 0.0 0.0 HOH
 4.564
 CB
 O
1hja 3 P00766 80.21 5e-51 X-RAY
 1998-01-14 CYS C:20 C:168 0.0 0.0 H -72.7 -36.2 0.0 0.0 0.0 HOH
 4.000
 CB
 O
1mtn 3 P00766 80.21 5e-51 X-RAY
 1996-08-17 CYS C:20 C:168 0.0 0.0 H -68.4 -48.1 0.0 0.0 0.0 HOH
 4.205
 CB
 O
CYS G:20 G:168 0.0 0.0 H -71.4 -39.3 NA NA NA
1n8o 3 P00766 80.21 5e-51 X-RAY
 2002-12-18 CYS C:20 C:168 0.0 0.0 H -66.8 -31.4 0.0 0.0 0.0 HOH
 4.332
 CB
 O
1vgc 3 P00766 80.21 5e-51 X-RAY
 1997-11-12 CYS C:20 C:168 0.0 0.0 H -73.1 -29.4 0.0 0.0 0.0 HOH
 4.351
 CB
 O
1yph 3 P00766 80.21 5e-51 X-RAY
 2006-02-14 CYS C:20 E:168 0.0 0.0 H -65.1 -28.9 0.0 0.0 0.0 SO4
HOH
 9.622
3.954
 O
CB
 O4
O
CYS F:20 F:168 0.0 0.0 H -60.8 -40.3 0.0 0.0 0.0 SO4
HOH
 9.641
4.005
 O
CB
 O3
O
2cha 3 P00766 80.21 5e-51 X-RAY
 1977-01-18 CYS C:20 C:168 0.0 0.0 H -87.8 -20.4 0.0 0.0 0.0 HOH
 9.756
 SG
 O
CYS F:20 G:168 0.0 0.0 H -87.8 -20.4 0.0 0.0 0.0
2gch 3 P00766 80.21 5e-51 X-RAY
 1980-07-09 CYS C:20 G:168 0.0 0.0 H -64.9 -26.9 0.0 0.0 0.0 HOH
 3.949
 CB
 O
2gct 3 P00766 80.21 5e-51 X-RAY
 1991-10-15 CYS C:20 C:168 0.0 0.0 H -59.8 -43.4 0.0 0.0 0.0 HOH
 4.109
 CB
 O
2gmt 3 P00766 80.21 5e-51 X-RAY
 1994-11-01 CYS C:20 C:168 0.0 0.0 H -46.8 -51.4 0.0 0.0 0.0 HOH
 4.637
 CB
 O
2p8o 3 P00766 80.21 5e-51 X-RAY
 2007-05-08 CYS C:20 C:168 0.0 0.0 H -64.1 -33.3 0.0 0.0 0.0 HOH
 4.169
 CB
 O
2vgc 3 P00766 80.21 5e-51 X-RAY
 1997-11-12 CYS C:20 C:168 0.0 0.0 H -69.9 -30.8 0.0 0.0 0.0 HOH
 4.020
 CB
 O
3bg4 3 P00766 80.21 5e-51 X-RAY
 2008-07-29 CYS C:20 C:168 0.0 0.0 H -52.7 -37.3 0.0 0.0 0.0 HOH
 4.223
 CB
 O
3gch 3 P00766 80.21 5e-51 X-RAY
 1990-10-15 CYS C:20 C:168 0.0 0.0 H -78.9 -37.3 0.0 0.0 0.0 HOH
 6.532
 CB
 O
3gct 3 P00766 80.21 5e-51 X-RAY
 1991-10-15 CYS C:20 G:168 0.0 0.0 H -63.0 -37.1 0.0 0.0 0.0 HOH
 4.114
 CB
 O
3vgc 3 P00766 80.21 5e-51 X-RAY
 1997-11-12 CYS C:20 C:168 0.0 0.0 H -70.4 -31.5 0.0 0.0 0.0 HOH
 4.372
 CB
 O
4cha 3 P00766 80.21 5e-51 X-RAY
 1985-04-01 CYS C:20 C:168 0.0 0.0 H -62.8 -34.1 0.0 0.0 0.0 HOH
 9.406
 SG
 O
CYS F:20 G:168 0.0 0.0 H -67.0 -33.8 0.0 0.0 0.0 HOH
 9.451
 SG
 O
4gch 3 P00766 80.21 5e-51 X-RAY
 1990-10-15 CYS C:20 G:168 0.0 0.0 H -66.0 -44.5 0.0 0.0 0.0 HOH
 7.475
 CB
 O
4vgc 3 P00766 80.21 5e-51 X-RAY
 1997-11-12 CYS C:20 C:168 0.0 0.0 H -76.8 -32.4 0.0 0.0 0.0 HOH
 4.810
 CB
 O
5cha 3 P00766 80.21 5e-51 X-RAY
 1985-04-01 CYS C:20 C:168 0.0 0.0 H -65.3 -31.6 0.0 0.0 0.0 HOH
 4.367
 CB
 O
CYS F:20 G:168 0.0 0.0 H -72.1 -27.4 0.0 0.0 0.0 HOH
 2.460
 CB
 O
5gch 3 P00766 80.21 5e-51 X-RAY
 1990-10-15 CYS C:20 G:168 0.0 0.0 H -76.8 -42.8 0.0 0.0 0.0 HOH
 6.856
 CB
 O
5r42 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 CYS C:20 C:168 0.0 0.0 H -61.1 -31.9 0.0 0.0 0.0 HOH
 4.223
 CB
 O
5r43 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 CYS C:20 C:168 0.0 0.0 H -59.0 -34.5 0.0 0.0 0.0 HOH
 4.075
 CB
 O
5r44 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 CYS C:20 C:168 0.0 0.0 H -61.0 -31.6 0.0 0.0 0.0 HOH
 4.227
 CB
 O
5r45 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 CYS C:20 C:168 0.0 0.0 H -58.5 -34.6 0.0 0.0 0.0 HOH
 4.109
 CB
 O
5r46 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 CYS C:20 C:168 0.0 0.0 H -62.0 -32.6 0.0 0.0 0.0 HOH
 4.205
 CB
 O
5r47 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 CYS C:20 C:168 0.0 0.0 H -60.4 -33.5 0.0 0.0 0.0 HOH
 4.093
 CB
 O
5r48 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 CYS C:20 C:168 0.0 0.0 H -61.4 -32.9 0.0 0.0 0.0 HOH
 4.234
 CB
 O
5r49 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 CYS C:20 C:168 0.0 0.0 H -60.7 -33.2 0.0 0.0 0.0 HOH
 4.115
 CB
 O
5r4a 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 CYS C:20 C:168 0.0 0.0 H -60.6 -32.2 0.0 0.0 0.0 HOH
 4.264
 CB
 O
5r4b 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 CYS C:20 C:168 0.0 0.0 H -60.0 -32.8 0.0 0.0 0.0 HOH
 4.132
 CB
 O
5r4c 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 CYS C:20 C:168 0.0 0.0 H -59.4 -33.0 0.0 0.0 0.0 HOH
 4.355
 CB
 O
5r4d 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 CYS C:20 C:168 0.0 0.0 H -59.5 -30.6 0.0 0.0 0.0 HOH
 4.210
 CB
 O
6cha 3 P00766 80.21 5e-51 X-RAY
 1987-04-16 CYS C:20 C:168 0.0 0.0 H -65.9 -31.5 0.0 0.0 0.0 HOH
 4.231
 CB
 O
CYS F:20 G:168 0.0 0.0 H -72.6 -35.4 0.0 0.0 0.0 HOH
 2.418
 CA
 O
6di8 3 P00766 80.21 5e-51 X-RAY
 2019-01-23 CYS C:20 C:168 0.0 0.0 H -66.0 -37.6 0.0 0.0 0.0 SO4
HOH
 9.800
4.053
 O
CB
 O4
O
CYS F:20 F:168 0.0 0.0 H -68.6 -36.5 NA NA NA
CYS I:20 I:168 0.0 0.0 H -68.7 -36.9 NA NA NA
CYS L:20 L:168 0.0 0.0 H -67.4 -37.3 NA NA NA
6gch 3 P00766 80.21 5e-51 X-RAY
 1990-10-15 CYS C:20 G:168 0.0 0.0 H -74.0 -40.3 0.0 0.0 0.0 HOH
 4.704
 N
 O
7gch 3 P00766 80.21 5e-51 X-RAY
 1990-10-15 CYS C:20 G:168 0.0 0.0 H -72.0 -38.2 0.0 0.0 0.0 HOH
 1.654
 O
 O
7jrx 3 P00766 80.21 5e-51 X-RAY
 2021-07-21 CYS C:20 C:168 0.0 0.0 H -62.1 -34.2 0.0 0.0 0.0 HOH
 3.925
 CA
 O
CYS G:20 c:168 0.0 0.0 H -65.3 -33.4 NA NA NA
8gch 3 P00766 80.21 5e-51 X-RAY
 1992-04-15 CYS C:20 G:168 0.0 0.0 H -63.5 -38.4 0.0 0.0 0.0 HOH
 4.001
 CB
 O
1afq 3 P00766 80.21 6e-51 X-RAY
 1997-09-17 CYS C:19 C:168 0.0 0.0 H -65.9 -29.7 0.0 0.0 0.0 HOH
 4.401
 CB
 O
3ru4 5 P00766 80.21 6e-51 X-RAY
 2012-08-29 CYS E:19 E:168 0.0 0.0 H -60.3 -37.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p17538-f1 1 P17538 100.0 0.0 CYS A:186 A:186 0.0 0.0 H -61.3 -33.2
af-q6gpi1-f1 1 Q6GPI1 95.82 0.0 CYS A:186 A:186 0.0 0.0 H -62.1 -36.8