Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 75258039 . A C CCDS32490.1:NM_001906.4:c.583Acc>Ccc_NP_001897.4:p.195T>P Homo sapiens chymotrypsinogen B1 (CTRB1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1acb 1 P00766 81.63 3e-148 X-RAY
 1993-10-31 LYS A:177 E:177 76.0 0.38 -113.7 179.0 76.0 0.38 0.0 HOH
 3.648
 CB
 O
1cgi 1 P00766 81.63 3e-148 X-RAY
 1993-10-31 LYS A:177 E:177 69.0 0.345 -98.7 -171.1 69.0 0.345 0.0 HOH
 5.212
 CG
 O
1cgj 1 P00766 81.63 3e-148 X-RAY
 1993-10-31 LYS A:177 E:177 67.0 0.335 -97.1 -175.1 66.0 0.33 0.005 B:P00995:0.005
 HOH
 2.635
 NZ
 O
1chg 1 P00766 81.63 3e-148 X-RAY
 1976-11-22 LYS A:177 A:177 84.0 0.42 -106.5 163.8 84.0 0.42 0.0
1ex3 1 P00766 81.63 3e-148 X-RAY
 2000-05-17 LYS A:177 A:177 69.0 0.345 -106.3 167.3 69.0 0.345 0.0 HOH
 4.068
 CG
 O
1gcd 1 P00766 81.63 3e-148 X-RAY
 1994-06-22 LYS A:177 A:177 71.0 0.355 -113.1 170.9 71.0 0.355 0.0 HOH
 2.636
 NZ
 O
1gl0 1 P00766 81.63 3e-148 X-RAY
 2001-11-28 LYS A:177 E:177 68.0 0.34 -92.0 -176.1 68.0 0.34 0.0 HOH
 3.879
 NZ
 O
1gl1 1 P00766 81.63 3e-148 X-RAY
 2001-11-28 LYS A:177 A:177 81.0 0.405 -96.5 173.3 81.0 0.405 0.0 HOH
 2.767
 NZ
 O
LYS B:177 B:177 83.0 0.415 -102.3 168.2 NA NA NA
LYS C:177 C:177 88.0 0.44 -105.4 170.9 NA NA NA
1k2i 1 P00766 81.63 3e-148 X-RAY
 2001-12-05 LYS A:177 1:177 75.0 0.375 -103.9 171.6 75.0 0.375 0.0 HOH
 3.552
 C
 O
1oxg 1 P00766 81.63 3e-148 X-RAY
 2004-05-18 LYS A:177 A:177 70.0 0.35 -103.8 167.6 70.0 0.35 0.0 SO4
SO4
HOH
 3.045
4.950
3.729
 CA
CG
CG
 O3
O2
O
1p2m 1 P00766 81.63 3e-148 X-RAY
 2004-04-20 LYS A:177 A:177 74.0 0.37 -103.5 174.2 74.0 0.37 0.0 HOH
 2.773
 NZ
 O
LYS C:177 C:177 76.0 0.38 -105.1 175.2 NA NA NA
1p2n 1 P00766 81.63 3e-148 X-RAY
 2004-04-20 LYS A:177 A:177 74.0 0.37 -104.6 172.7 74.0 0.37 0.0 HOH
 2.795
 NZ
 O
LYS C:177 C:177 75.0 0.375 -105.2 174.9 NA NA NA
1p2o 1 P00766 81.63 3e-148 X-RAY
 2004-04-20 LYS A:177 A:177 76.0 0.38 -98.9 177.3 76.0 0.38 0.0 HOH
 2.874
 O
 O
LYS C:177 C:177 76.0 0.38 -105.8 173.4 NA NA NA
1p2q 1 P00766 81.63 3e-148 X-RAY
 2004-04-20 LYS A:177 A:177 75.0 0.375 -104.0 172.4 75.0 0.375 0.0 SO4
HOH
 5.288
2.719
 CB
NZ
 O2
O
LYS C:177 C:177 75.0 0.375 -104.2 173.4 NA NA NA
1t7c 1 P00766 81.63 3e-148 X-RAY
 2005-03-08 LYS A:177 A:177 76.0 0.38 -103.2 174.0 76.0 0.38 0.0 SO4
HOH
 5.514
2.935
 CB
O
 O4
O
LYS C:177 C:177 76.0 0.38 -104.4 173.1 NA NA NA
1t8l 1 P00766 81.63 3e-148 X-RAY
 2005-03-08 LYS A:177 A:177 77.0 0.385 -101.9 173.8 77.0 0.385 0.0 SO4
HOH
 5.065
2.741
 CB
NZ
 O4
O
LYS C:177 C:177 75.0 0.375 -101.6 174.1 NA NA NA
1t8m 1 P00766 81.63 3e-148 X-RAY
 2005-03-08 LYS A:177 A:177 75.0 0.375 -103.7 173.3 75.0 0.375 0.0 SO4
HOH
 5.221
2.982
 CB
O
 O4
O
LYS C:177 C:177 75.0 0.375 -105.9 172.8 NA NA NA
1t8n 1 P00766 81.63 3e-148 X-RAY
 2005-03-08 LYS A:177 A:177 76.0 0.38 -102.4 174.6 76.0 0.38 0.0 HOH
 2.912
 O
 O
LYS C:177 C:177 75.0 0.375 -103.8 173.8 NA NA NA
1t8o 1 P00766 81.63 3e-148 X-RAY
 2005-03-08 LYS A:177 A:177 75.0 0.375 -104.5 173.1 75.0 0.375 0.0 SO4
HOH
 5.159
2.728
 CB
NZ
 O4
O
LYS C:177 C:177 74.0 0.37 -103.2 174.5 NA NA NA
2cga 1 P00766 81.63 3e-148 X-RAY
 1987-04-16 LYS A:177 A:177 76.0 0.38 -97.9 160.9 76.0 0.38 0.0 HOH
 3.010
 NZ
 O
LYS B:177 B:177 77.0 0.385 -110.0 169.8 77.0 0.385 0.0 HOH
 3.663
 C
 O
2y6t 1 P00766 81.63 3e-148 X-RAY
 2011-04-20 LYS A:177 A:177 72.0 0.36 -111.6 172.0 64.0 0.32 0.04 E:B1JSA0:0.04
 SO4
 6.088
 CE
 O2
LYS B:177 B:177 75.0 0.375 -95.8 178.4 73.0 0.365 0.01 F:B1JSA0:0.01
 SO4
 6.273
 CG
 O3
LYS C:177 C:177 65.0 0.325 -102.7 175.3 NA NA NA
LYS D:177 D:177 78.0 0.39 -102.7 171.8 NA NA NA
3t62 1 P00766 81.63 3e-148 X-RAY
 2012-08-01 LYS A:177 A:177 68.0 0.34 -106.2 176.1 68.0 0.34 0.0 HOH
 2.675
 NZ
 O
LYS C:177 B:177 74.0 0.37 -110.2 179.5 NA NA NA
LYS E:177 C:177 68.0 0.34 -106.5 172.6 NA NA NA
4q2k 1 P00766 81.63 3e-148 X-RAY
 2014-07-23 LYS A:177 A:177 117.0 0.585 -98.3 166.2 117.0 0.585 0.0 5BF
HOH
 7.303
7.053
 CE
CG
 C11
O
LYS B:177 B:177 116.0 0.58 -91.9 167.0 NA NA NA
LYS C:177 C:177 92.0 0.46 -81.6 166.2 NA NA NA
LYS D:177 D:177 126.0 0.63 -84.4 164.8 126.0 0.63 0.0 5BF
HOH
 7.122
3.390
 CE
C
 C11
O
5j4q 1 P00766 81.63 3e-148 X-RAY
 2017-04-12 LYS A:177 A:177 76.0 0.38 -107.1 173.1 76.0 0.38 0.0 HOH
 3.533
 O
 O
5j4s 1 P00766 81.63 3e-148 X-RAY
 2017-04-12 LYS A:177 A:177 85.0 0.425 -112.6 169.2 85.0 0.425 0.0 HOH
 1.615
 HZ3
 O
7kty 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 LYS A:177 A:177 82.0 0.41 -113.1 173.4 82.0 0.41 0.0 HOH
 3.940
 CB
 O
7ktz 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 LYS A:177 A:177 78.0 0.39 -108.6 168.9 78.0 0.39 0.0 HOH
 2.809
 NZ
 O
7ku0 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 LYS A:177 A:177 77.0 0.385 -110.6 170.7 77.0 0.385 0.0 HOH
 3.560
 CA
 O
7ku1 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 LYS A:177 A:177 62.0 0.31 -98.8 -176.3 62.0 0.31 0.0 HOH
 3.982
 CB
 O
7ku2 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 LYS A:177 A:177 73.0 0.365 -106.3 173.6 73.0 0.365 0.0 HOH
 3.863
 CB
 O
7ku3 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 LYS A:177 A:177 80.0 0.4 -107.1 169.2 80.0 0.4 0.0 HOH
 3.708
 CA
 O
1dlk 2 P00766 80.87 2e-137 X-RAY
 2000-05-03 LYS B:162 B:177 73.0 0.365 -100.3 174.3 73.0 0.365 0.0 HOH
 3.757
 CB
 O
LYS D:162 D:177 70.0 0.35 -108.6 174.2 NA NA NA
1ab9 3 P00766 80.21 5e-51 X-RAY
 1997-08-20 LYS C:29 C:177 115.0 0.575 -107.0 168.0 70.0 0.35 0.225 B:P00766:0.225
 HOH
 3.677
 C
 O
1ca0 3 P00766 80.21 5e-51 X-RAY
 1997-07-23 LYS C:29 C:177 113.0 0.565 -104.4 168.8 75.0 0.375 0.19 B:P00766:0.19
 HOH
 2.769
 O
 O
LYS G:29 H:177 111.0 0.555 -95.3 -177.7 NA NA NA
1cbw 3 P00766 80.21 5e-51 X-RAY
 1997-07-23 LYS C:29 C:177 111.0 0.555 -116.8 178.7 72.0 0.36 0.195 B:P00766:0.195
 HOH
 3.590
 NZ
 O
LYS G:29 H:177 107.0 0.535 -128.9 177.5 NA NA NA
1cho 3 P00766 80.21 5e-51 X-RAY
 1988-07-16 LYS C:29 G:177 120.0 0.6 -109.7 167.6 68.0 0.34 0.26 B:P00766:0.26
 HOH
 2.627
 NZ
 O
1gct 3 P00766 80.21 5e-51 X-RAY
 1991-10-15 LYS C:29 C:177 114.0 0.57 -105.5 175.1 69.0 0.345 0.225 B:P00766:0.225
 HOH
 3.595
 O
 O
1gg6 3 P00766 80.21 5e-51 X-RAY
 2000-09-20 LYS C:29 C:177 120.0 0.6 -113.0 166.3 76.0 0.38 0.22 B:P00766:0.22
 SO4
EDO
HOH
 8.172
6.915
2.693
 O
CE
NZ
 O2
O1
O
1ggd 3 P00766 80.21 5e-51 X-RAY
 2000-09-20 LYS C:29 C:177 120.0 0.6 -103.4 172.6 70.0 0.35 0.25 B:P00766:0.25
 HOH
 2.640
 NZ
 O
1gha 3 P00766 80.21 5e-51 X-RAY
 1994-06-22 LYS C:29 G:177 124.0 0.62 -99.0 170.0 77.0 0.385 0.235 B:P00766:0.235
 HOH
 4.178
 NZ
 O
1ghb 3 P00766 80.21 5e-51 X-RAY
 1994-06-22 LYS C:29 G:177 111.0 0.555 -113.2 172.6 64.0 0.32 0.235 B:P00766:0.235
 HOH
 2.922
 NZ
 O
1gmc 3 P00766 80.21 5e-51 X-RAY
 1993-10-31 LYS C:29 G:177 104.0 0.52 -95.7 174.1 64.0 0.32 0.2 B:P00766:0.2
 HOH
 3.205
 NZ
 O
1gmd 3 P00766 80.21 5e-51 X-RAY
 1993-10-31 LYS C:29 G:177 120.0 0.6 -104.5 168.2 56.0 0.28 0.32 B:P00766:0.32
 HEX
HOH
 6.781
3.615
 CE
CD
 C6
O
1gmh 3 P00766 80.21 5e-51 X-RAY
 1994-09-30 LYS C:29 G:177 107.0 0.535 -106.6 170.6 66.0 0.33 0.205 B:P00766:0.205
 HOH
 3.562
 CB
 O
1hja 3 P00766 80.21 5e-51 X-RAY
 1998-01-14 LYS C:29 C:177 117.0 0.585 -107.7 179.0 70.0 0.35 0.235 B:P00766:0.235
 HOH
 4.203
 CB
 O
1mtn 3 P00766 80.21 5e-51 X-RAY
 1996-08-17 LYS C:29 C:177 111.0 0.555 -81.4 -175.3 67.0 0.335 0.22 B:P00766:0.22
 HOH
 3.710
 NZ
 O
LYS G:29 G:177 112.0 0.56 -84.2 178.1 NA NA NA
1n8o 3 P00766 80.21 5e-51 X-RAY
 2002-12-18 LYS C:29 C:177 118.0 0.59 -109.3 176.3 52.0 0.26 0.33 D:P23827:0.145
B:P00766:0.225
D:P23827:0.01
 HOH
 3.747
 CE
 O
1vgc 3 P00766 80.21 5e-51 X-RAY
 1997-11-12 LYS C:29 C:177 118.0 0.59 -97.4 171.5 73.0 0.365 0.225 B:P00766:0.225
 HOH
 6.562
 CB
 O
1yph 3 P00766 80.21 5e-51 X-RAY
 2006-02-14 LYS C:29 E:177 111.0 0.555 -111.1 174.6 74.0 0.37 0.185 B:P00766:0.185
 HOH
 2.944
 NZ
 O
LYS F:29 F:177 117.0 0.585 -107.8 166.9 70.0 0.35 0.235 E:P00766:0.235
 HOH
 2.799
 NZ
 O
2cha 3 P00766 80.21 5e-51 X-RAY
 1977-01-18 LYS C:29 C:177 115.0 0.575 -104.9 157.7 74.0 0.37 0.205 B:P00766:0.205
 HOH
 6.041
 CB
 O
LYS F:29 G:177 116.0 0.58 -104.9 157.7 75.0 0.375 0.205 E:P00766:0.205
2gch 3 P00766 80.21 5e-51 X-RAY
 1980-07-09 LYS C:29 G:177 121.0 0.605 -112.9 169.2 77.0 0.385 0.22 B:P00766:0.22
 HOH
 3.157
 CE
 O
2gct 3 P00766 80.21 5e-51 X-RAY
 1991-10-15 LYS C:29 C:177 116.0 0.58 -106.2 172.6 70.0 0.35 0.23 B:P00766:0.23
 HOH
 3.832
 O
 O
2gmt 3 P00766 80.21 5e-51 X-RAY
 1994-11-01 LYS C:29 C:177 114.0 0.57 -113.7 170.1 71.0 0.355 0.215 B:P00766:0.215
 HIN
HOH
 7.861
2.843
 NZ
NZ
 C10
O
2p8o 3 P00766 80.21 5e-51 X-RAY
 2007-05-08 LYS C:29 C:177 114.0 0.57 -101.1 165.2 67.0 0.335 0.235 B:P00766:0.235
 HOH
 3.603
 CA
 O
2vgc 3 P00766 80.21 5e-51 X-RAY
 1997-11-12 LYS C:29 C:177 120.0 0.6 -92.4 169.7 77.0 0.385 0.215 B:P00766:0.215
 HOH
 6.570
 CB
 O
3bg4 3 P00766 80.21 5e-51 X-RAY
 2008-07-29 LYS C:29 C:177 125.0 0.625 -93.5 169.3 79.0 0.395 0.23 B:P00766:0.23
 HOH
 2.942
 NZ
 O
3gch 3 P00766 80.21 5e-51 X-RAY
 1990-10-15 LYS C:29 C:177 114.0 0.57 -115.2 174.6 72.0 0.36 0.21 B:P00766:0.21
 HOH
 4.202
 CA
 O
3gct 3 P00766 80.21 5e-51 X-RAY
 1991-10-15 LYS C:29 G:177 120.0 0.6 -105.1 175.8 76.0 0.38 0.22 B:P00766:0.22
 HOH
 3.513
 C
 O
3vgc 3 P00766 80.21 5e-51 X-RAY
 1997-11-12 LYS C:29 C:177 118.0 0.59 -98.6 169.7 76.0 0.38 0.21 B:P00766:0.21
 HOH
 6.573
 CB
 O
4cha 3 P00766 80.21 5e-51 X-RAY
 1985-04-01 LYS C:29 C:177 112.0 0.56 -103.0 166.9 69.0 0.345 0.215 B:P00766:0.215
 HOH
 4.273
 CD
 O
LYS F:29 G:177 110.0 0.55 -100.8 171.6 63.0 0.315 0.235 E:P00766:0.235
 HOH
 3.949
 CD
 O
4gch 3 P00766 80.21 5e-51 X-RAY
 1990-10-15 LYS C:29 G:177 119.0 0.595 -108.5 155.6 78.0 0.39 0.205 B:P00766:0.205
 HOH
 4.066
 CG
 O
4vgc 3 P00766 80.21 5e-51 X-RAY
 1997-11-12 LYS C:29 C:177 117.0 0.585 -97.7 175.1 78.0 0.39 0.195 B:P00766:0.195
 HOH
 6.434
 CB
 O
5cha 3 P00766 80.21 5e-51 X-RAY
 1985-04-01 LYS C:29 C:177 128.0 0.64 -102.5 164.4 76.0 0.38 0.26 B:P00766:0.26
 HOH
 3.903
 CE
 O
LYS F:29 G:177 101.0 0.505 -104.0 170.6 61.0 0.305 0.2 E:P00766:0.2
 HOH
 3.482
 C
 O
5gch 3 P00766 80.21 5e-51 X-RAY
 1990-10-15 LYS C:29 G:177 121.0 0.605 -115.1 175.4 83.0 0.415 0.19 B:P00766:0.19
 HOH
 3.791
 CA
 O
5r42 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 LYS C:29 C:177 116.0 0.58 -107.1 167.8 73.0 0.365 0.215 B:P00766:0.215
 HOH
 3.553
 CA
 O
5r43 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 LYS C:29 C:177 118.0 0.59 -109.6 166.7 72.0 0.36 0.23 B:P00766:0.23
 HOH
 2.756
 NZ
 O
5r44 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 LYS C:29 C:177 118.0 0.59 -107.7 167.0 74.0 0.37 0.22 B:P00766:0.22
 HOH
 3.576
 CA
 O
5r45 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 LYS C:29 C:177 119.0 0.595 -108.1 166.1 72.0 0.36 0.235 B:P00766:0.235
 HOH
 3.583
 CA
 O
5r46 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 LYS C:29 C:177 116.0 0.58 -109.8 168.0 73.0 0.365 0.215 B:P00766:0.215
 HOH
 3.514
 CA
 O
5r47 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 LYS C:29 C:177 116.0 0.58 -108.0 166.8 70.0 0.35 0.23 B:P00766:0.23
 HOH
 3.099
 NZ
 O
5r48 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 LYS C:29 C:177 118.0 0.59 -109.7 168.0 74.0 0.37 0.22 B:P00766:0.22
 HOH
 3.536
 CA
 O
5r49 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 LYS C:29 C:177 118.0 0.59 -108.6 165.8 71.0 0.355 0.235 B:P00766:0.235
 HOH
 2.838
 NZ
 O
5r4a 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 LYS C:29 C:177 118.0 0.59 -111.3 168.0 74.0 0.37 0.22 B:P00766:0.22
 HOH
 3.619
 CA
 O
5r4b 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 LYS C:29 C:177 117.0 0.585 -111.1 165.4 72.0 0.36 0.225 B:P00766:0.225
 HOH
 2.715
 NZ
 O
5r4c 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 LYS C:29 C:177 118.0 0.59 -112.8 169.6 74.0 0.37 0.22 B:P00766:0.22
 HOH
 3.611
 CA
 O
5r4d 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 LYS C:29 C:177 116.0 0.58 -111.1 166.2 72.0 0.36 0.22 B:P00766:0.22
 HOH
 2.752
 NZ
 O
6cha 3 P00766 80.21 5e-51 X-RAY
 1987-04-16 LYS C:29 C:177 126.0 0.63 -107.5 169.7 76.0 0.38 0.25 B:P00766:0.25
 HOH
 2.664
 CD
 O
LYS F:29 G:177 106.0 0.53 -107.7 -177.4 65.0 0.325 0.205 E:P00766:0.205
 HOH
 2.710
 CE
 O
6di8 3 P00766 80.21 5e-51 X-RAY
 2019-01-23 LYS C:29 C:177 124.0 0.62 -106.6 168.1 73.0 0.365 0.255 B:P00766:0.255
 SO4
HOH
 4.646
2.634
 CG
NZ
 O4
O
LYS F:29 F:177 120.0 0.6 -108.0 169.1 NA NA NA
LYS I:29 I:177 119.0 0.595 -107.0 167.8 NA NA NA
LYS L:29 L:177 123.0 0.615 -108.0 168.5 NA NA NA
6gch 3 P00766 80.21 5e-51 X-RAY
 1990-10-15 LYS C:29 G:177 109.0 0.545 -108.2 -179.9 62.0 0.31 0.235 B:P00766:0.235
 HOH
 4.064
 CD
 O
7gch 3 P00766 80.21 5e-51 X-RAY
 1990-10-15 LYS C:29 G:177 118.0 0.59 -108.5 172.9 71.0 0.355 0.235 B:P00766:0.235
 HOH
 3.210
 NZ
 O
7jrx 3 P00766 80.21 5e-51 X-RAY
 2021-07-21 LYS C:29 C:177 117.0 0.585 -104.5 170.2 71.0 0.355 0.23 B:P00766:0.23
 HOH
 2.737
 NZ
 O
LYS G:29 c:177 120.0 0.6 -104.4 169.1 NA NA NA
8gch 3 P00766 80.21 5e-51 X-RAY
 1992-04-15 LYS C:29 G:177 112.0 0.56 -113.9 160.9 64.0 0.32 0.24 B:P00766:0.24
 HOH
 2.833
 NZ
 O
1afq 3 P00766 80.21 6e-51 X-RAY
 1997-09-17 LYS C:28 C:177 120.0 0.6 -103.9 170.5 73.0 0.365 0.235 B:P00766:0.235
 HOH
 3.626
 C
 O
3ru4 5 P00766 80.21 6e-51 X-RAY
 2012-08-29 LYS E:28 E:177 115.0 0.575 -104.1 165.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p17538-f1 1 P17538 100.0 0.0 THR A:195 A:195 31.0 0.221 -108.4 -179.6
af-q6gpi1-f1 1 Q6GPI1 95.82 0.0 THR A:195 A:195 33.0 0.236 -111.5 178.4