Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 75258636 . G A CCDS32490.1:NM_001906.4:c.664Gat>Aat_NP_001897.4:p.222D>N Homo sapiens chymotrypsinogen B1 (CTRB1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1acb 1 P00766 81.63 3e-148 X-RAY
 1993-10-31 ASN A:204 E:204 158.0 0.988 T 58.2 53.6 158.0 0.988 0.0 HOH
 2.817
 OD1
 O
1cgi 1 P00766 81.63 3e-148 X-RAY
 1993-10-31 ASN A:204 E:204 169.0 1.0 T 60.2 36.7 169.0 1.0 0.0 HOH
 3.295
 N
 O
1cgj 1 P00766 81.63 3e-148 X-RAY
 1993-10-31 ASN A:204 E:204 171.0 1.0 T 60.5 37.1 171.0 1.0 0.0 HOH
 4.232
 ND2
 O
1chg 1 P00766 81.63 3e-148 X-RAY
 1976-11-22 ASN A:204 A:204 155.0 0.969 T 46.1 41.5 155.0 0.969 0.0
1ex3 1 P00766 81.63 3e-148 X-RAY
 2000-05-17 ASN A:204 A:204 160.0 1.0 T 60.6 49.5 160.0 1.0 0.0
1gcd 1 P00766 81.63 3e-148 X-RAY
 1994-06-22 ASN A:204 A:204 159.0 0.994 T 31.9 50.2 159.0 0.994 0.0 HOH
 3.569
 N
 O
1gl0 1 P00766 81.63 3e-148 X-RAY
 2001-11-28 ASN A:204 E:204 158.0 0.988 T 52.7 33.1 158.0 0.988 0.0 HOH
 3.463
 ND2
 O
1gl1 1 P00766 81.63 3e-148 X-RAY
 2001-11-28 ASN A:204 A:204 160.0 1.0 T 50.3 46.0 160.0 1.0 0.0 HOH
 3.069
 N
 O
ASN B:204 B:204 156.0 0.975 T 58.1 47.9 NA NA NA
ASN C:204 C:204 160.0 1.0 T 68.6 39.7 NA NA NA
1k2i 1 P00766 81.63 3e-148 X-RAY
 2001-12-05 ASN A:204 1:204 166.0 1.0 T 54.5 38.4 166.0 1.0 0.0 HOH
 3.194
 N
 O
1oxg 1 P00766 81.63 3e-148 X-RAY
 2004-05-18 ASN A:204 A:204 168.0 1.0 T 55.4 45.6 168.0 1.0 0.0 HOH
 3.897
 C
 O
1p2m 1 P00766 81.63 3e-148 X-RAY
 2004-04-20 ASN A:204 A:204 164.0 1.0 T 58.9 37.2 164.0 1.0 0.0 HOH
 3.154
 N
 O
ASN C:204 C:204 162.0 1.0 T 65.3 21.7 NA NA NA
1p2n 1 P00766 81.63 3e-148 X-RAY
 2004-04-20 ASN A:204 A:204 164.0 1.0 T 54.7 42.2 164.0 1.0 0.0 HOH
 2.697
 ND2
 O
ASN C:204 C:204 161.0 1.0 T 66.7 24.0 NA NA NA
1p2o 1 P00766 81.63 3e-148 X-RAY
 2004-04-20 ASN A:204 A:204 163.0 1.0 T 55.1 40.5 163.0 1.0 0.0 HOH
 3.258
 N
 O
ASN C:204 C:204 161.0 1.0 T 65.8 42.6 NA NA NA
1p2q 1 P00766 81.63 3e-148 X-RAY
 2004-04-20 ASN A:204 A:204 164.0 1.0 T 57.5 39.8 164.0 1.0 0.0 HOH
 2.667
 ND2
 O
ASN C:204 C:204 157.0 0.981 S 68.0 53.0 NA NA NA
1t7c 1 P00766 81.63 3e-148 X-RAY
 2005-03-08 ASN A:204 A:204 160.0 1.0 T 58.2 42.4 160.0 1.0 0.0 HOH
 2.661
 OD1
 O
ASN C:204 C:204 159.0 0.994 T 67.7 47.2 NA NA NA
1t8l 1 P00766 81.63 3e-148 X-RAY
 2005-03-08 ASN A:204 A:204 163.0 1.0 T 57.6 39.4 163.0 1.0 0.0 HOH
 2.700
 ND2
 O
ASN C:204 C:204 160.0 1.0 T 61.4 44.9 NA NA NA
1t8m 1 P00766 81.63 3e-148 X-RAY
 2005-03-08 ASN A:204 A:204 162.0 1.0 T 61.4 35.6 162.0 1.0 0.0 HOH
 3.259
 N
 O
ASN C:204 C:204 165.0 1.0 T 67.6 42.8 NA NA NA
1t8n 1 P00766 81.63 3e-148 X-RAY
 2005-03-08 ASN A:204 A:204 165.0 1.0 T 61.1 37.2 165.0 1.0 0.0 HOH
 2.920
 N
 O
ASN C:204 C:204 162.0 1.0 T 68.3 45.8 NA NA NA
1t8o 1 P00766 81.63 3e-148 X-RAY
 2005-03-08 ASN A:204 A:204 162.0 1.0 T 59.8 37.2 162.0 1.0 0.0 HOH
 3.203
 N
 O
ASN C:204 C:204 159.0 0.994 T 65.8 41.6 NA NA NA
2cga 1 P00766 81.63 3e-148 X-RAY
 1987-04-16 ASN A:204 A:204 161.0 1.0 T 57.3 41.3 150.0 0.938 0.062 B:P00766:0.069
 HOH
 2.814
 O
 O
ASN B:204 B:204 162.0 1.0 T 60.4 40.8 162.0 1.0 0.0 HOH
 3.974
 N
 O
2y6t 1 P00766 81.63 3e-148 X-RAY
 2011-04-20 ASN A:204 A:204 157.0 0.981 T 60.8 39.9 157.0 0.981 0.0
ASN B:204 B:204 165.0 1.0 T 49.9 81.0 165.0 1.0 0.0
ASN C:204 C:204 160.0 1.0 T 52.5 42.3 NA NA NA
ASN D:204 D:204 160.0 1.0 T 63.4 24.6 NA NA NA
3t62 1 P00766 81.63 3e-148 X-RAY
 2012-08-01 ASN A:204 A:204 154.0 0.963 S 75.8 40.5 154.0 0.963 0.0 HOH
 2.809
 OD1
 O
ASN C:204 B:204 162.0 1.0 T 66.6 46.0 NA NA NA
ASN E:204 C:204 162.0 1.0 T 70.4 46.4 NA NA NA
4q2k 1 P00766 81.63 3e-148 X-RAY
 2014-07-23 ASN A:204 A:204 157.0 0.981 T 46.6 45.6 157.0 0.981 0.0 HOH
 3.836
 ND2
 O
ASN B:204 B:204 156.0 0.975 T 56.0 40.2 NA NA NA
ASN C:204 C:204 106.0 NA S 85.7 48.7 NA NA NA
ASN D:204 D:204 158.0 0.988 T 48.9 52.3 158.0 0.988 0.0 HOH
 3.629
 CB
 O
5j4q 1 P00766 81.63 3e-148 X-RAY
 2017-04-12 ASN A:204 A:204 167.0 1.0 T 47.5 47.9 167.0 1.0 0.0 HOH
 2.499
 N
 O
5j4s 1 P00766 81.63 3e-148 X-RAY
 2017-04-12 ASN A:204 A:204 158.0 0.988 T 51.9 44.9 158.0 0.988 0.0 HOH
 2.891
 HB2
 O
7kty 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 ASN A:204 A:204 158.0 0.988 T 57.3 38.2 158.0 0.988 0.0 HOH
 3.012
 O
 O
7ktz 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 ASN A:204 A:204 162.0 1.0 T 56.2 44.6 162.0 1.0 0.0 HOH
 3.974
 N
 O
7ku0 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 ASN A:204 A:204 146.0 0.912 T 61.4 45.6 146.0 0.912 0.0 HOH
 2.937
 O
 O
7ku1 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 ASN A:204 A:204 151.0 0.944 T 58.4 43.5 151.0 0.944 0.0 HOH
 8.998
 ND2
 O
7ku2 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 ASN A:204 A:204 161.0 1.0 T 56.3 54.2 161.0 1.0 0.0
7ku3 1 P00766 81.63 3e-148 X-RAY
 2021-03-10 ASN A:204 A:204 148.0 0.925 T 66.0 42.2 148.0 0.925 0.0 HOH
 3.205
 O
 O
1dlk 2 P00766 80.87 2e-137 X-RAY
 2000-05-03 ASN B:189 B:204 156.0 0.975 T 61.1 46.6 156.0 0.975 0.0 HOH
 5.038
 O
 O
ASN D:189 D:204 161.0 1.0 T 56.5 46.7 NA NA NA
1ab9 3 P00766 80.21 5e-51 X-RAY
 1997-08-20 ASN C:56 C:204 160.0 1.0 T 55.7 39.2 160.0 1.0 0.0 HOH
 3.017
 O
 O
1ca0 3 P00766 80.21 5e-51 X-RAY
 1997-07-23 ASN C:56 C:204 161.0 1.0 T 58.2 39.4 161.0 1.0 0.0 HOH
 3.123
 ND2
 O
ASN G:56 H:204 163.0 1.0 T 64.8 -0.1 NA NA NA
1cbw 3 P00766 80.21 5e-51 X-RAY
 1997-07-23 ASN C:56 C:204 161.0 1.0 T 70.4 28.3 161.0 1.0 0.0 HOH
 8.232
 N
 O
ASN G:56 H:204 162.0 1.0 S 67.9 67.4 NA NA NA
1cho 3 P00766 80.21 5e-51 X-RAY
 1988-07-16 ASN C:56 G:204 145.0 0.906 T 77.0 45.4 145.0 0.906 0.0 HOH
 2.899
 N
 O
1gct 3 P00766 80.21 5e-51 X-RAY
 1991-10-15 ASN C:56 C:204 167.0 1.0 T 56.3 38.8 167.0 1.0 0.0 HOH
 3.403
 N
 O
1gg6 3 P00766 80.21 5e-51 X-RAY
 2000-09-20 ASN C:56 C:204 165.0 1.0 T 57.4 47.5 165.0 1.0 0.0 EDO
HOH
 5.734
2.555
 O
O
 O1
O
1ggd 3 P00766 80.21 5e-51 X-RAY
 2000-09-20 ASN C:56 C:204 157.0 0.981 T 55.1 36.4 157.0 0.981 0.0 HOH
 3.045
 ND2
 O
1gha 3 P00766 80.21 5e-51 X-RAY
 1994-06-22 ASN C:56 G:204 170.0 1.0 T 62.2 40.5 170.0 1.0 0.0 HOH
 3.074
 O
 O
1ghb 3 P00766 80.21 5e-51 X-RAY
 1994-06-22 ASN C:56 G:204 167.0 1.0 T 65.4 35.6 167.0 1.0 0.0 HOH
 3.330
 N
 O
1gmc 3 P00766 80.21 5e-51 X-RAY
 1993-10-31 ASN C:56 G:204 168.0 1.0 T 61.8 37.7 168.0 1.0 0.0 HOH
 3.325
 N
 O
1gmd 3 P00766 80.21 5e-51 X-RAY
 1993-10-31 ASN C:56 G:204 173.0 1.0 T 61.7 36.3 173.0 1.0 0.0 HOH
 3.250
 N
 O
1gmh 3 P00766 80.21 5e-51 X-RAY
 1994-09-30 ASN C:56 G:204 166.0 1.0 T 59.1 34.1 166.0 1.0 0.0 HOH
 2.675
 O
 O
1hja 3 P00766 80.21 5e-51 X-RAY
 1998-01-14 ASN C:56 C:204 160.0 1.0 T 65.7 39.8 160.0 1.0 0.0 HOH
 2.860
 N
 O
1mtn 3 P00766 80.21 5e-51 X-RAY
 1996-08-17 ASN C:56 C:204 167.0 1.0 T 52.1 37.6 167.0 1.0 0.0 HOH
 6.709
 N
 O
ASN G:56 G:204 162.0 1.0 G 61.5 39.9 NA NA NA
1n8o 3 P00766 80.21 5e-51 X-RAY
 2002-12-18 ASN C:56 C:204 158.0 0.988 T 66.3 39.7 158.0 0.988 0.0 HOH
 2.721
 N
 O
1vgc 3 P00766 80.21 5e-51 X-RAY
 1997-11-12 ASN C:56 C:204 169.0 1.0 T 56.5 35.7 169.0 1.0 0.0 HOH
 2.760
 O
 O
1yph 3 P00766 80.21 5e-51 X-RAY
 2006-02-14 ASN C:56 E:204 160.0 1.0 T 60.7 34.6 160.0 1.0 0.0 HOH
 2.724
 OD1
 O
ASN F:56 F:204 159.0 0.994 T 59.7 35.9 159.0 0.994 0.0 HOH
 2.706
 OD1
 O
2cha 3 P00766 80.21 5e-51 X-RAY
 1977-01-18 ASN C:56 C:204 164.0 1.0 T 45.3 30.8 164.0 1.0 0.0 HOH
 6.528
 O
 O
ASN F:56 G:204 163.0 1.0 T 45.3 30.8 163.0 1.0 0.0
2gch 3 P00766 80.21 5e-51 X-RAY
 1980-07-09 ASN C:56 G:204 168.0 1.0 T 57.9 30.1 168.0 1.0 0.0 HOH
 3.476
 N
 O
2gct 3 P00766 80.21 5e-51 X-RAY
 1991-10-15 ASN C:56 C:204 165.0 1.0 T 51.4 43.0 165.0 1.0 0.0 HOH
 3.234
 N
 O
2gmt 3 P00766 80.21 5e-51 X-RAY
 1994-11-01 ASN C:56 C:204 165.0 1.0 T 41.3 43.0 165.0 1.0 0.0 HOH
 2.706
 ND2
 O
2p8o 3 P00766 80.21 5e-51 X-RAY
 2007-05-08 ASN C:56 C:204 162.0 1.0 T 51.3 35.9 162.0 1.0 0.0 HOH
 6.183
 CB
 O
2vgc 3 P00766 80.21 5e-51 X-RAY
 1997-11-12 ASN C:56 C:204 167.0 1.0 T 58.7 30.9 167.0 1.0 0.0 HOH
 2.810
 O
 O
3bg4 3 P00766 80.21 5e-51 X-RAY
 2008-07-29 ASN C:56 C:204 160.0 1.0 T 16.7 81.2 160.0 1.0 0.0 HOH
 5.569
 O
 O
3gch 3 P00766 80.21 5e-51 X-RAY
 1990-10-15 ASN C:56 C:204 174.0 1.0 T 52.9 52.6 174.0 1.0 0.0 HOH
 4.332
 OD1
 O
3gct 3 P00766 80.21 5e-51 X-RAY
 1991-10-15 ASN C:56 G:204 166.0 1.0 T 61.5 39.0 166.0 1.0 0.0 HOH
 3.218
 N
 O
3vgc 3 P00766 80.21 5e-51 X-RAY
 1997-11-12 ASN C:56 C:204 168.0 1.0 T 59.0 34.2 168.0 1.0 0.0 HOH
 2.749
 O
 O
4cha 3 P00766 80.21 5e-51 X-RAY
 1985-04-01 ASN C:56 C:204 162.0 1.0 T 51.9 38.9 162.0 1.0 0.0
ASN F:56 G:204 163.0 1.0 T 52.6 44.2 163.0 1.0 0.0
4gch 3 P00766 80.21 5e-51 X-RAY
 1990-10-15 ASN C:56 G:204 171.0 1.0 T 66.3 40.4 171.0 1.0 0.0 HOH
 4.007
 N
 O
4vgc 3 P00766 80.21 5e-51 X-RAY
 1997-11-12 ASN C:56 C:204 168.0 1.0 T 57.2 37.2 168.0 1.0 0.0 HOH
 2.917
 O
 O
5cha 3 P00766 80.21 5e-51 X-RAY
 1985-04-01 ASN C:56 C:204 155.0 0.969 T 57.6 32.9 155.0 0.969 0.0 HOH
 1.946
 OD1
 O
ASN F:56 G:204 151.0 0.944 T 61.3 47.8 151.0 0.944 0.0 HOH
 2.919
 N
 O
5gch 3 P00766 80.21 5e-51 X-RAY
 1990-10-15 ASN C:56 G:204 167.0 1.0 T 58.7 51.3 167.0 1.0 0.0 HOH
 4.093
 O
 O
5r42 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 ASN C:56 C:204 169.0 1.0 T 51.8 39.0 169.0 1.0 0.0 HOH
 2.859
 N
 O
5r43 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 ASN C:56 C:204 173.0 1.0 T 47.5 42.6 173.0 1.0 0.0 HOH
 2.834
 N
 O
5r44 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 ASN C:56 C:204 166.0 1.0 T 51.0 39.9 165.0 1.0 0.0 B:P00766:0.006
 HOH
 2.902
 OD1
 O
5r45 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 ASN C:56 C:204 163.0 1.0 T 48.1 41.9 162.0 1.0 0.0 B:P00766:0.006
 HOH
 2.844
 N
 O
5r46 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 ASN C:56 C:204 157.0 0.981 T 50.0 38.7 157.0 0.981 0.0 HOH
 2.911
 O
 O
5r47 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 ASN C:56 C:204 165.0 1.0 T 49.9 41.4 165.0 1.0 0.0 HOH
 2.759
 O
 O
5r48 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 ASN C:56 C:204 159.0 0.994 T 50.2 38.0 159.0 0.994 0.0 HOH
 3.513
 N
 O
5r49 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 ASN C:56 C:204 171.0 1.0 T 48.3 42.5 171.0 1.0 0.0 HOH
 2.792
 O
 O
5r4a 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 ASN C:56 C:204 163.0 1.0 T 51.7 38.4 163.0 1.0 0.0 HOH
 3.503
 N
 O
5r4b 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 ASN C:56 C:204 163.0 1.0 T 49.5 49.5 163.0 1.0 0.0 HOH
 1.786
 N
 O
5r4c 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 ASN C:56 C:204 165.0 1.0 T 51.8 37.8 165.0 1.0 0.0 HOH
 2.997
 OD1
 O
5r4d 3 P00766 80.21 5e-51 X-RAY
 2021-09-01 ASN C:56 C:204 158.0 0.988 T 50.8 38.4 158.0 0.988 0.0 HOH
 1.484
 O
 O
6cha 3 P00766 80.21 5e-51 X-RAY
 1987-04-16 ASN C:56 C:204 156.0 0.975 T 61.0 42.9 156.0 0.975 0.0 HOH
 2.736
 N
 O
ASN F:56 G:204 151.0 0.944 S 79.3 37.2 151.0 0.944 0.0 HOH
 5.637
 C
 O
6di8 3 P00766 80.21 5e-51 X-RAY
 2019-01-23 ASN C:56 C:204 159.0 0.994 T 57.8 37.0 159.0 0.994 0.0 HOH
 2.639
 ND2
 O
ASN F:56 F:204 166.0 1.0 T 62.3 35.0 NA NA NA
ASN I:56 I:204 157.0 0.981 T 59.0 36.4 NA NA NA
ASN L:56 L:204 154.0 0.963 T 61.6 35.7 NA NA NA
6gch 3 P00766 80.21 5e-51 X-RAY
 1990-10-15 ASN C:56 G:204 158.0 0.988 T 59.7 34.6 158.0 0.988 0.0 HOH
 2.640
 N
 O
7gch 3 P00766 80.21 5e-51 X-RAY
 1990-10-15 ASN C:56 G:204 164.0 1.0 T 61.8 40.9 164.0 1.0 0.0 HOH
 4.565
 ND2
 O
7jrx 3 P00766 80.21 5e-51 X-RAY
 2021-07-21 ASN C:56 C:204 157.0 0.981 T 57.3 42.1 157.0 0.981 0.0 HOH
 5.061
 N
 O
ASN G:56 c:204 157.0 0.981 T 49.9 43.8 NA NA NA
8gch 3 P00766 80.21 5e-51 X-RAY
 1992-04-15 ASN C:56 G:204 157.0 0.981 T 44.6 45.9 157.0 0.981 0.0 HOH
 2.630
 ND2
 O
1afq 3 P00766 80.21 6e-51 X-RAY
 1997-09-17 ASN C:55 C:204 170.0 1.0 T 59.0 36.7 146.0 0.912 0.088 D:None:0.15
 0FG
HOH
 5.079
2.756
 CB
O
 C3
O
3ru4 5 P00766 80.21 6e-51 X-RAY
 2012-08-29 ASN E:55 E:204 166.0 1.0 T 48.6 53.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p17538-f1 1 P17538 100.0 0.0 ASP A:222 A:222 157.0 1.0 T 51.3 32.4
af-q6gpi1-f1 1 Q6GPI1 95.82 0.0 ASP A:222 A:222 159.0 1.0 T 51.2 36.9