Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr16 | 87436663 | . | A | C | CCDS10960.1:NM_022818.4:c.338tAt>tCt_NP_073729.1:p.113Y>S | Homo sapiens microtubule associated protein 1 light chain 3 beta (MAP1LC3B), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
5gmv | 1 | Q9GZQ8 | 100.0 | 1e-89 |
X-RAY |
2017-03-08 | TYR | A:113 | B:113 | 1.0 | 0.004 | E | -113.3 | 141.7 | 1.0 | 0.004 | 0.0 |
HOH |
5.307 |
CE2 |
O |
||
TYR | C:113 | A:113 | 0.0 | 0.0 | E | -114.7 | 142.4 | NA | NA | NA | |||||||||||||
2zjd | 1 | Q9GZQ8 | 100.0 | 1e-89 |
X-RAY |
2008-06-03 | TYR | A:118 | A:113 | 0.0 | 0.0 | E | -122.2 | 144.5 | 0.0 | 0.0 | 0.0 |
HOH |
2.987 |
OH |
O |
||
TYR | C:118 | C:113 | 0.0 | 0.0 | E | -121.3 | 153.1 | NA | NA | NA | |||||||||||||
5d94 | 1 | Q9GZQ8 | 100.0 | 1e-89 |
X-RAY |
2015-10-21 | TYR | A:118 | A:113 | 1.0 | 0.004 | E | -105.2 | 151.5 | 1.0 | 0.004 | 0.0 |
HOH |
2.775 |
OH |
O |
||
6lan | 1 | Q8IVM0,Q9GZQ8 | 99.2 | 1e-88 |
X-RAY |
2020-09-30 | TYR | A:123 | A:113 | 3.0 | 0.013 | E | -111.5 | 144.6 | 3.0 | 0.013 | 0.0 |
HOH |
3.027 |
HE2 |
O |
||
5wrd | 1 | Q9CQV6 | 95.2 | 2e-86 |
X-RAY |
2017-03-29 | TYR | A:113 | A:113 | 2.0 | 0.009 | E | -105.6 | 141.6 | 2.0 | 0.009 | 0.0 |
GOL HOH |
7.767 6.780 |
CA N |
O1 O |
||
TYR | B:113 | B:113 | 1.0 | 0.004 | E | -114.6 | 146.3 | NA | NA | NA | |||||||||||||
5yiq | 1 | Q9CQV6 | 95.2 | 2e-86 |
X-RAY |
2018-05-23 | TYR | A:113 | A:113 | 1.0 | 0.004 | E | -117.9 | 158.4 | 1.0 | 0.004 | 0.0 |
HOH |
6.747 |
N |
O |
||
5yis | 1 | Q9CQV6 | 95.2 | 2e-86 |
X-RAY |
2018-05-23 | TYR | A:113 | A:113 | 3.0 | 0.013 | E | -112.7 | 152.8 | 3.0 | 0.013 | 0.0 |
GOL HOH |
7.769 5.120 |
CA CE2 |
O1 O |
||
TYR | B:113 | B:113 | 0.0 | 0.0 | E | -121.4 | 153.6 | NA | NA | NA | |||||||||||||
2n9x | 1 | Q9GZQ8 | 100.0 | 3e-86 |
NMR |
2016-12-14 | TYR | A:113 | A:113 | 4.0 | 0.017 | E | -127.8 | 148.5 | 4.0 | 0.017 | 0.0 | ||||||
6j04 | 1 | Q9GZQ8 | 99.19 | 6e-86 |
X-RAY |
2019-11-06 | TYR | A:113 | A:113 | 4.0 | 0.017 | E | -118.7 | 150.0 | 4.0 | 0.017 | 0.0 |
SO4 HOH |
8.395 2.815 |
OH OH |
O2 O |
||
TYR | B:113 | B:113 | 3.0 | 0.013 | E | -114.9 | 145.2 | NA | NA | NA | |||||||||||||
TYR | C:113 | C:113 | 3.0 | 0.013 | E | -104.5 | 151.6 | NA | NA | NA | |||||||||||||
TYR | D:113 | D:113 | 0.0 | 0.0 | E | -109.6 | 150.0 | NA | NA | NA | |||||||||||||
2z0e | 2 | Q62625 | 95.97 | 6e-86 |
X-RAY |
2007-05-22 | TYR | B:118 | B:113 | 1.0 | 0.004 | E | -113.9 | 152.0 | 1.0 | 0.004 | 0.0 |
HOH |
3.138 |
OH |
O |
||
2zzp | 2 | Q62625 | 95.97 | 6e-86 |
X-RAY |
2009-03-03 | TYR | B:118 | B:113 | 2.0 | 0.009 | E | -121.5 | 149.9 | 2.0 | 0.009 | 0.0 |
HOH |
3.139 |
OH |
O |
||
5xad | 1 | Q9GZQ8 | 100.0 | 2e-85 |
X-RAY |
2017-07-12 | TYR | A:112 | A:113 | 1.0 | 0.004 | E | -113.5 | 143.9 | 1.0 | 0.004 | 0.0 |
HOH |
4.905 |
OH |
O |
||
TYR | B:112 | B:113 | 2.0 | 0.009 | E | -112.0 | 143.8 | NA | NA | NA | |||||||||||||
2k6q | 1 | Q62625 | 98.33 | 3e-85 |
NMR |
2008-09-02 | TYR | A:114 | A:113 | 0.0 | 0.0 | E | -103.2 | 152.4 | 0.0 | 0.0 | 0.0 | ||||||
5xac | 1 | Q9GZQ8 | 100.0 | 4e-85 |
X-RAY |
2017-07-12 | TYR | A:123 | A:113 | 1.0 | 0.004 | E | -109.5 | 149.1 | 1.0 | 0.004 | 0.0 |
HOH |
3.423 |
OH |
O |
||
TYR | B:123 | B:113 | 0.0 | 0.0 | E | -120.0 | 149.6 | 0.0 | 0.0 | 0.0 |
HOH |
3.506 |
OH |
O |
|||||||||
TYR | C:123 | C:113 | 4.0 | 0.017 | E | -109.2 | 144.4 | 4.0 | 0.017 | 0.0 |
HOH |
4.751 |
OH |
O |
|||||||||
TYR | D:123 | D:113 | 3.0 | 0.013 | E | -111.0 | 146.3 | 3.0 | 0.013 | 0.0 |
HOH |
3.495 |
OH |
O |
|||||||||
5xae | 1 | Q9GZQ8 | 100.0 | 4e-85 |
X-RAY |
2017-07-12 | TYR | A:135 | A:111 | 2.0 | 0.009 | E | -114.3 | 150.3 | 2.0 | 0.009 | 0.0 |
HOH |
4.678 |
OH |
O |
||
TYR | B:135 | B:111 | 1.0 | 0.004 | E | -113.4 | 151.5 | 1.0 | 0.004 | 0.0 |
HOH |
3.490 |
OH |
O |
|||||||||
TYR | C:135 | C:111 | 2.0 | 0.009 | E | -110.3 | 152.9 | 2.0 | 0.009 | 0.0 |
HOH |
6.553 |
OH |
O |
|||||||||
TYR | D:135 | D:111 | 2.0 | 0.009 | E | -113.9 | 150.3 | 2.0 | 0.009 | 0.0 |
HOH |
3.309 |
OH |
O |
|||||||||
1ugm | 1 | Q62625 | 98.33 | 5e-85 |
X-RAY |
2004-07-06 | TYR | A:118 | A:113 | 1.0 | 0.004 | E | -127.2 | 152.9 | 1.0 | 0.004 | 0.0 |
HOH |
3.443 |
OH |
O |
||
2z0d | 2 | Q62625 | 98.33 | 5e-85 |
X-RAY |
2007-05-22 | TYR | B:118 | B:113 | 1.0 | 0.004 | E | -117.4 | 147.5 | 1.0 | 0.004 | 0.0 |
HOH |
2.785 |
OH |
O |
||
5ms2 | 2 | Q9GZQ8 | 100.0 | 6e-85 |
X-RAY |
2017-04-19 | TYR | B:118 | B:113 | 2.0 | 0.009 | E | -125.6 | 152.4 | 2.0 | 0.009 | 0.0 |
HOH |
9.499 |
CA |
O |
||
5v4k | 1 | Q9GZQ8 | 100.0 | 2e-84 |
X-RAY |
2017-05-17 | TYR | A:126 | A:1113 | 3.0 | 0.013 | E | -111.9 | 147.5 | 3.0 | 0.013 | 0.0 |
HOH |
2.919 |
OH |
O |
||
TYR | B:126 | B:1113 | 1.0 | 0.004 | E | -108.9 | 149.6 | 1.0 | 0.004 | 0.0 |
HOH |
2.950 |
OH |
O |
|||||||||
3vtw | 1 | Q96CV9,Q9GZQ8 | 100.0 | 3e-84 |
X-RAY |
2013-06-26 | TYR | A:143 | A:128 | 1.0 | 0.004 | E | -111.6 | 147.9 | 1.0 | 0.004 | 0.0 |
HOH |
3.381 |
OH |
O |
||
TYR | B:143 | B:128 | 0.0 | 0.0 | E | -128.0 | 140.1 | NA | NA | NA | |||||||||||||
TYR | C:143 | C:128 | 0.0 | 0.0 | E | -129.7 | 151.5 | NA | NA | NA | |||||||||||||
3wao | 1 | O75143,Q9GZQ8 | 100.0 | 3e-84 |
X-RAY |
2013-12-25 | TYR | A:128 | A:129 | 3.0 | 0.013 | E | -119.7 | 156.4 | 3.0 | 0.013 | 0.0 | ||||||
TYR | B:128 | B:129 | 1.0 | 0.004 | E | -118.2 | 137.9 | NA | NA | NA | |||||||||||||
TYR | C:128 | C:129 | 1.0 | 0.004 | E | -128.4 | 149.9 | NA | NA | NA | |||||||||||||
TYR | D:128 | D:129 | 2.0 | 0.009 | E | -111.5 | 152.3 | NA | NA | NA | |||||||||||||
3x0w | 1 | Q9GZQ8 | 100.0 | 5e-84 |
X-RAY |
2015-01-14 | TYR | A:128 | A:140 | 1.0 | 0.004 | E | -117.5 | 149.1 | 1.0 | 0.004 | 0.0 |
HOH |
3.012 |
OH |
O |
||
TYR | B:128 | B:140 | 1.0 | 0.004 | E | -114.9 | 146.8 | NA | NA | NA | |||||||||||||
3vtv | 1 | Q96CV9,Q9GZQ8 | 100.0 | 5e-84 |
X-RAY |
2013-06-26 | TYR | A:128 | A:128 | 0.0 | 0.0 | E | -112.7 | 160.0 | 0.0 | 0.0 | 0.0 |
HOH |
3.337 |
OH |
O |
||
4waa | 1 | Q9GZQ8 | 100.0 | 6e-84 |
X-RAY |
2015-09-09 | TYR | A:128 | A:129 | 0.0 | 0.0 | E | -102.4 | 144.3 | 0.0 | 0.0 | 0.0 |
HOH |
4.788 |
OH |
O |
||
TYR | B:128 | B:129 | 1.0 | 0.004 | E | -108.2 | 145.1 | 1.0 | 0.004 | 0.0 |
HOH |
5.142 |
OH |
O |
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5dcn | 1 | Q9GZQ8 | 100.0 | 6e-84 |
X-RAY |
2016-03-09 | TYR | A:120 | A:113 | 1.0 | 0.004 | E | -115.6 | 148.4 | 1.0 | 0.004 | 0.0 |
SO4 HOH |
6.879 2.912 |
O OH |
O3 O |
||
3vtu | 1 | Q9GZQ8 | 99.16 | 7e-84 |
X-RAY |
2013-06-26 | TYR | A:117 | A:117 | 0.0 | 0.0 | E | -112.4 | 153.5 | 0.0 | 0.0 | 0.0 |
SO4 HOH |
6.578 3.484 |
OH OH |
O1 O |
||
7elg | 1 | Q9GZQ8 | 99.16 | 7e-84 |
X-RAY |
2021-10-13 | TYR | A:117 | A:117 | 0.0 | 0.0 | E | -114.3 | 151.9 | 0.0 | 0.0 | 0.0 |
HOH |
3.269 |
OH |
O |
||
5ms5 | 1 | Q5ZUV9,Q9GZQ8 | 100.0 | 9e-84 |
X-RAY |
2017-04-19 | TYR | A:131 | A:113 | 1.0 | 0.004 | E | -112.0 | 150.7 | 1.0 | 0.004 | 0.0 |
HOH |
3.190 |
OH |
O |
||
TYR | B:131 | B:113 | 4.0 | 0.017 | E | -112.1 | 150.4 | NA | NA | NA | |||||||||||||
5ms6 | 1 | Q9GZQ8 | 100.0 | 9e-84 |
X-RAY |
2017-04-19 | TYR | A:131 | A:113 | 2.0 | 0.009 | E | -113.3 | 146.8 | 2.0 | 0.009 | 0.0 |
HOH |
2.637 |
OH |
O |
||
TYR | B:131 | B:113 | 3.0 | 0.013 | E | -115.2 | 149.9 | NA | NA | NA | |||||||||||||
2lue | 1 | Q9GZQ8 | 100.0 | 7e-82 |
NMR |
2013-07-17 | TYR | A:113 | A:113 | 1.0 | 0.004 | E | -125.0 | 156.8 | 1.0 | 0.004 | 0.0 | ||||||
5w9a | 2 | Q9GZQ8 | 100.0 | 7e-81 |
X-RAY |
2018-10-10 | TYR | B:110 | C:113 | 4.0 | 0.017 | E | -116.7 | 140.7 | 4.0 | 0.017 | 0.0 | ||||||
TYR | C:110 | D:113 | 3.0 | 0.013 | E | -117.0 | 138.6 | 3.0 | 0.013 | 0.0 | |||||||||||||
7r9w | 1 | Q9H492 | 82.5 | 3e-72 |
X-RAY |
2022-01-12 | TYR | A:115 | A:113 | 2.0 | 0.009 | E | -117.9 | 148.1 | 2.0 | 0.009 | 0.0 |
JO4 HOH |
8.901 5.411 |
CD2 OH |
C11 O |
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7r9z | 1 | Q9H492 | 82.5 | 3e-72 |
X-RAY |
2022-01-12 | TYR | A:115 | A:113 | 2.0 | 0.009 | E | -118.3 | 149.3 | 2.0 | 0.009 | 0.0 |
HOH |
4.897 |
OH |
O |
||
7ra0 | 1 | Q9H492 | 82.5 | 3e-72 |
X-RAY |
2022-01-12 | TYR | A:115 | A:113 | 3.0 | 0.013 | E | -113.7 | 149.7 | 3.0 | 0.013 | 0.0 |
HOH |
3.408 |
OH |
O |
||
5cx3 | 1 | Q9H492 | 82.5 | 4e-72 |
X-RAY |
2016-08-03 | TYR | A:113 | A:113 | 3.0 | 0.013 | E | -118.7 | 148.3 | 3.0 | 0.013 | 0.0 |
HOH |
2.553 |
OH |
O |
||
TYR | B:113 | B:113 | 2.0 | 0.009 | E | -115.9 | 149.5 | NA | NA | NA | |||||||||||||
TYR | C:113 | C:113 | 3.0 | 0.013 | E | -112.3 | 142.9 | 3.0 | 0.013 | 0.0 |
HOH |
2.731 |
OH |
O |
|||||||||
TYR | D:113 | D:113 | 2.0 | 0.009 | E | -112.7 | 142.5 | NA | NA | NA | |||||||||||||
3eci | 1 | Q9H492 | 82.5 | 5e-72 |
X-RAY |
2008-10-14 | TYR | A:114 | A:113 | 3.0 | 0.013 | E | -107.6 | 142.0 | 3.0 | 0.013 | 0.0 | ||||||
TYR | B:114 | B:113 | 4.0 | 0.017 | E | -115.9 | 159.1 | NA | NA | NA | |||||||||||||
3wal | 1 | Q9H492 | 80.99 | 4e-71 |
X-RAY |
2013-12-25 | TYR | A:117 | A:117 | 2.0 | 0.009 | E | -115.7 | 151.8 | 2.0 | 0.009 | 0.0 |
HOH |
6.252 |
O |
O |
||
5dpr | 1 | Q9Y4G2,Q9H492 | 81.67 | 5e-71 |
X-RAY |
2016-09-28 | TYR | A:128 | A:124 | 1.0 | 0.004 | E | -122.4 | 147.9 | 1.0 | 0.004 | 0.0 |
HOH |
6.494 |
H |
O |
||
TYR | B:128 | B:124 | 0.0 | 0.0 | E | -123.5 | 147.2 | NA | NA | NA | |||||||||||||
TYR | C:128 | C:124 | 0.0 | 0.0 | E | -123.8 | 146.4 | NA | NA | NA | |||||||||||||
TYR | D:128 | D:124 | 1.0 | 0.004 | E | -123.4 | 148.0 | NA | NA | NA | |||||||||||||
3wan | 1 | O75143,Q9H492 | 81.67 | 5e-71 |
X-RAY |
2013-12-25 | TYR | A:128 | A:129 | 0.0 | 0.0 | E | -111.4 | 149.3 | 0.0 | 0.0 | 0.0 |
HOH |
3.669 |
OH |
O |
||
TYR | B:128 | B:129 | 1.0 | 0.004 | E | -120.0 | 156.4 | 1.0 | 0.004 | 0.0 |
HOH |
2.833 |
OH |
O |
|||||||||
4zdv | 1 | Q9H492 | 82.35 | 6e-71 |
X-RAY |
2015-06-03 | TYR | A:125 | A:113 | 0.0 | 0.0 | E | -116.1 | 149.7 | 0.0 | 0.0 | 0.0 |
HOH |
3.330 |
OH |
O |
||
6tbe | 1 | Q9H492 | 81.9 | 1e-68 |
X-RAY |
2020-11-18 | TYR | A:113 | A:117 | 2.0 | 0.009 | E | -114.3 | 150.3 | 2.0 | 0.009 | 0.0 |
NOV HOH |
9.480 3.053 |
CE2 OH |
C24 O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-q9gzq8-f1 | 1 | Q9GZQ8 | 100.0 | 4e-90 | TYR | A:113 | A:113 | 1.0 | 0.004 | E | -105.9 | 140.7 | |
af-a6nce7-f1 | 1 | A6NCE7 | 99.2 | 5e-89 | CYS | A:113 | A:113 | 3.0 | 0.022 | E | -89.0 | 127.4 | |
af-q9h492-f1 | 1 | Q9H492 | 82.5 | 1e-72 | TYR | A:113 | A:113 | 2.0 | 0.009 | E | -113.2 | 142.1 |