Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 21976762 . G A CCDS10601.1:NM_003366.2:c.548cGg>cAg_NP_003357.2:p.183R>Q Homo sapiens ubiquinol-cytochrome c reductase core protein II (UQCRC2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5xte 10 P22695 100.0 0.0 EM
 2017-08-30 ARG J:149 K:183 160.0 0.711 S -64.1 -38.4 61.0 0.271 0.44 U:P22695:0.44
ARG U:149 W:183 181.0 0.804 S -64.8 -38.5 73.0 0.324 0.48 J:P22695:0.48
5xth 67 P22695 100.0 0.0 EM
 2017-09-13 ARG PB:149 AK:183 161.0 0.716 S -64.1 -38.4 61.0 0.271 0.445 AC:P22695:0.444
ARG AC:149 AW:183 180.0 0.8 S -64.9 -38.5 73.0 0.324 0.476 PB:P22695:0.476
5xti 67 P22695 100.0 0.0 EM
 2017-09-13 ARG PB:149 AK:183 163.0 0.724 S -64.2 -38.3 61.0 0.271 0.453 AC:P22695:0.453
ARG AC:149 AW:183 179.0 0.796 S -64.9 -38.5 73.0 0.324 0.472 PB:P22695:0.471
1sqb 2 P23004 89.4 0.0 X-RAY
 2004-09-07 ARG B:183 B:169 163.0 0.724 S -95.0 -2.8 66.0 0.293 0.431 B:P23004:0.431
 HOH
 4.368
 O
 O
1sqp 2 P23004 89.4 0.0 X-RAY
 2005-11-01 ARG B:183 B:169 144.0 0.64 S -87.5 9.9 50.0 0.222 0.418 B:P23004:0.418
 HOH
 3.750
 CZ
 O
4d6t 2 P23004 89.4 0.0 X-RAY
 2015-01-14 ARG B:183 B:169 129.0 0.573 -111.4 -69.2 129.0 0.573 0.0
4d6u 2 P23004 89.4 0.0 X-RAY
 2015-01-14 ARG B:183 B:169 135.0 0.6 S -123.5 -44.2 135.0 0.6 0.0
5okd 2 P23004 89.4 0.0 X-RAY
 2018-02-28 ARG B:183 B:169 167.0 0.742 S -89.4 -38.3 167.0 0.742 0.0 HOH
 8.023
 NH1
 O
6fo6 3 P23004 89.4 0.0 EM
 2018-02-28 ARG C:183 B:169 129.0 0.573 S -93.9 -63.1 58.0 0.258 0.315 L:P23004:0.316
ARG L:183 O:169 124.0 0.551 S -93.8 -63.2 56.0 0.249 0.302 C:P23004:0.302
4d6t 10 P23004 89.18 0.0 X-RAY
 2015-01-14 ARG L:183 O:169 138.0 0.613 -65.6 -60.1 NA NA NA
4d6u 11 P23004 89.18 0.0 X-RAY
 2015-01-14 ARG L:183 O:169 141.0 0.627 S -121.4 -47.7 NA NA NA
6fo0 2 P23004 89.18 0.0 EM
 2018-02-28 ARG B:183 O:169 133.0 0.591 -114.0 -60.3 43.0 0.191 0.4 L:P23004:0.4
ARG L:183 B:169 133.0 0.591 -113.9 -60.2 44.0 0.196 0.395 B:P23004:0.396
6fo2 2 P23004 89.18 0.0 EM
 2018-02-28 ARG B:183 O:169 127.0 0.564 -113.1 -59.7 47.0 0.209 0.355 L:P23004:0.356
ARG L:183 B:169 127.0 0.564 -113.1 -59.7 49.0 0.218 0.346 B:P23004:0.347
5gup 46 ? 88.3 0.0 EM
 2017-03-29 ARG VA:183 v:183 151.0 0.671 S -67.9 -38.9 105.0 0.467 0.204 GB:None:0.204
ARG GB:183 6:183 114.0 0.507 S -100.0 20.9 37.0 0.164 0.343 VA:None:0.342
1be3 2 P23004 89.29 0.0 X-RAY
 1999-01-13 ARG B:169 B:169 170.0 0.756 S -103.7 -34.0 170.0 0.756 0.0
1bgy 2 P23004 89.29 0.0 X-RAY
 1999-01-06 ARG B:169 B:169 178.0 0.791 S -116.4 -45.7 86.0 0.382 0.409 M:P23004:0.409
ARG M:169 N:169 178.0 0.791 S -115.6 -49.0 88.0 0.391 0.4 B:P23004:0.4
1l0l 2 P23004 89.29 0.0 X-RAY
 2003-04-08 ARG B:169 B:169 157.0 0.698 S -80.7 -21.4 157.0 0.698 0.0
1l0n 2 P23004 89.29 0.0 X-RAY
 2003-04-08 ARG B:169 B:169 152.0 0.676 S -100.8 10.2 152.0 0.676 0.0
1ntk 2 P23004 89.29 0.0 X-RAY
 2003-10-07 ARG B:169 B:169 145.0 0.644 S -67.9 -29.5 54.0 0.24 0.404 B:P23004:0.404
 HOH
 4.185
 N
 O
1ntm 2 P23004 89.29 0.0 X-RAY
 2003-10-07 ARG B:169 B:169 138.0 0.613 S -106.1 3.2 64.0 0.284 0.329 B:P23004:0.329
 HOH
 4.586
 O
 O
1ntz 2 P23004 89.29 0.0 X-RAY
 2003-10-07 ARG B:169 B:169 151.0 0.671 S -103.3 12.2 74.0 0.329 0.342 B:P23004:0.342
 HOH
 9.748
 N
 O
1nu1 2 P23004 89.29 0.0 X-RAY
 2003-10-07 ARG B:169 B:169 144.0 0.64 S -114.8 -4.5 75.0 0.333 0.307 B:P23004:0.307
1pp9 2 P23004 89.29 0.0 X-RAY
 2004-07-20 ARG B:169 B:169 163.0 0.724 S -87.2 -23.0 73.0 0.324 0.4 L:P23004:0.4
 HOH
 2.847
 O
 O
ARG L:169 O:169 163.0 0.724 S -85.2 -22.9 73.0 0.324 0.4 B:P23004:0.4
 HOH
 3.619
 O
 O
1ppj 2 P23004 89.29 0.0 X-RAY
 2004-07-20 ARG B:169 B:169 163.0 0.724 S -81.0 -20.1 73.0 0.324 0.4 L:P23004:0.4
 HOH
 2.924
 O
 O
ARG L:169 O:169 160.0 0.711 S -79.2 -21.4 72.0 0.32 0.391 B:P23004:0.391
 HOH
 4.047
 NE
 O
1sqq 2 P23004 89.29 0.0 X-RAY
 2005-10-25 ARG B:169 B:169 152.0 0.676 S -69.9 -25.7 60.0 0.267 0.409 B:P23004:0.409
 HOH
 3.759
 O
 O
1sqv 2 P23004 89.29 0.0 X-RAY
 2005-09-06 ARG B:169 B:169 136.0 0.604 S -100.0 4.8 53.0 0.236 0.368 B:P23004:0.369
 HOH
 3.930
 O
 O
1sqx 2 P23004 89.29 0.0 X-RAY
 2005-09-06 ARG B:169 B:169 153.0 0.68 S -78.6 -14.8 63.0 0.28 0.4 B:P23004:0.4
 HOH
 4.353
 N
 O
2a06 2 P23004 89.29 0.0 X-RAY
 2005-06-21 ARG B:169 B:169 157.0 0.698 S -79.8 -23.9 66.0 0.293 0.405 L:P23004:0.404
 UNL
HOH
 8.925
3.060
 N
O
 O1
O
ARG L:169 O:169 156.0 0.693 S -80.8 -26.3 68.0 0.302 0.391 B:P23004:0.391
 UNL
HOH
 3.700
4.677
 O
O
 O1
O
2fyu 2 P23004 89.29 0.0 X-RAY
 2006-08-29 ARG B:169 B:169 141.0 0.627 S -68.0 -19.6 56.0 0.249 0.378 B:P23004:0.378
 HOH
 7.961
 NH2
 O
2ybb 10 P23004 89.29 0.0 EM
 2011-10-19 ARG J:169 B:169 163.0 0.724 S -87.2 -22.9 72.0 0.32 0.404 IA:P23004:0.404
 HOH
 2.847
 O
 O
ARG IA:169 b:169 160.0 0.711 S -85.2 -22.9 72.0 0.32 0.391 J:P23004:0.391
 HOH
 3.619
 O
 O
5gpn 2 P23004 89.29 0.0 EM
 2017-04-05 ARG B:169 B:169 78.0 NA S -116.3 -45.7 65.0 NA NA N:P23004:NA
ARG N:169 N:169 75.0 NA S -115.6 -48.9 67.0 NA NA B:P23004:NA
5klv 2 P23004 89.29 0.0 X-RAY
 2016-10-12 ARG B:169 B:169 145.0 0.644 S -82.7 -29.2 61.0 0.271 0.373 B:P23004:0.373
 GOL
HOH
 2.730
5.649
 O
HH21
 H12
O
5luf 2 P23004 89.29 0.0 EM
 2016-11-30 ARG B:169 m:169 178.0 0.791 S -116.4 -45.7 88.0 0.391 0.4 M:P23004:0.4
ARG M:169 n:169 178.0 0.791 S -115.6 -49.0 87.0 0.387 0.404 B:P23004:0.404
6nhg 2 P23004 89.29 0.0 X-RAY
 2019-06-19 ARG B:169 B:169 153.0 0.68 S -76.2 -21.9 62.0 0.276 0.404 B:P23004:0.404
 HOH
 4.069
 HH12
 O
7o37 2 Q9DB77 85.42 0.0 EM
 2021-10-13 LYS B:169 B:169 124.0 0.62 E -92.5 -17.8 31.0 0.155 0.465 L:Q9DB77:0.465
LYS L:169 M:169 130.0 0.65 S -72.5 -45.0 42.0 0.21 0.44 B:Q9DB77:0.44
7o3c 2 Q9DB77 85.42 0.0 EM
 2021-10-13 LYS B:169 B:169 123.0 0.615 S -98.0 -20.5 32.0 0.16 0.455 L:Q9DB77:0.455
LYS L:169 M:169 129.0 0.645 S -82.2 -61.2 36.0 0.18 0.465 B:Q9DB77:0.465
7o3e 2 Q9DB77 85.42 0.0 EM
 2021-10-13 LYS B:169 B:169 118.0 0.59 E -94.6 -38.9 34.0 0.17 0.42 I:Q9DB77:0.42
LYS I:169 M:169 122.0 0.61 S -67.1 -50.5 30.0 0.15 0.46 B:Q9DB77:0.46
7o3h 2 Q9DB77 85.42 0.0 EM
 2021-10-13 LYS B:169 B:169 130.0 0.65 S -93.8 -56.0 36.0 0.18 0.47 L:Q9DB77:0.47
LYS L:169 M:169 133.0 0.665 S -75.2 -43.1 40.0 0.2 0.465 B:Q9DB77:0.465
6q9e 2 W5Q0F9 89.29 0.0 EM
 2019-08-21 ARG B:169 a2:169 151.0 0.671 S -88.3 6.5 63.0 0.28 0.391 L:W5Q0F9:0.391
ARG L:169 a4:169 147.0 0.653 S -88.5 16.7 59.0 0.262 0.391 B:W5Q0F9:0.391
6qbx 2 W5Q0F9 89.29 0.0 EM
 2019-08-21 ARG B:169 a2:169 141.0 0.627 S -92.6 14.7 55.0 0.244 0.383 L:W5Q0F9:0.382
ARG L:169 a4:169 146.0 0.649 S -94.9 10.5 66.0 0.293 0.356 B:W5Q0F9:0.356
6qc2 30 W5Q0F9 89.29 0.0 EM
 2019-08-21 ARG DA:169 a2:169 150.0 0.667 S -96.1 7.4 62.0 0.276 0.391 NA:W5Q0F9:0.391
ARG NA:169 a4:169 136.0 0.604 S -112.2 6.0 79.0 0.351 0.253 DA:W5Q0F9:0.253
6qc3 2 W5Q0F9 89.29 0.0 EM
 2019-08-21 ARG B:169 a2:169 142.0 0.631 S -89.7 20.6 68.0 0.302 0.329 L:W5Q0F9:0.329
ARG L:169 a4:169 145.0 0.644 S -91.0 15.6 78.0 0.347 0.297 B:W5Q0F9:0.298
6qc4 2 W5Q0F9 89.29 0.0 EM
 2019-08-21 ARG B:169 a2:169 142.0 0.631 S -91.2 11.3 59.0 0.262 0.369 L:W5Q0F9:0.369
ARG L:169 a4:169 158.0 0.702 S -88.3 9.2 48.0 0.213 0.489 B:W5Q0F9:0.489
5j4z 52 W5Q0F9 89.34 0.0 EM
 2016-09-21 ARG DB:153 AB:169 78.0 NA -108.9 -61.7 78.0 NA NA
ARG OB:153 AM:169 77.0 NA -108.7 -61.7 77.0 NA NA
5j7y 52 W5Q0F9 89.34 0.0 EM
 2016-09-21 ARG DB:153 AB:169 77.0 NA -108.9 -61.7 77.0 NA NA
ARG OB:153 AM:169 77.0 NA -108.7 -61.7 77.0 NA NA
5j8k 52 W5Q0F9 89.34 0.0 EM
 2016-09-21 ARG DB:153 AB:169 76.0 NA -108.9 -61.7 76.0 NA NA
ARG OB:153 AM:169 78.0 NA -108.8 -61.7 78.0 NA NA
5nmi 2 P23004 89.34 0.0 X-RAY
 2017-06-14 ARG B:153 B:169 147.0 0.653 S -94.1 -72.2 65.0 0.289 0.364 M:P23004:0.364
ARG M:153 O:169 150.0 0.667 S -94.3 -72.1 65.0 0.289 0.378 B:P23004:0.378
6zfs 2 P23004 89.29 0.0 X-RAY
 2021-06-30 ARG B:150 B:169 163.0 0.724 S -91.7 -36.2 163.0 0.724 0.0
6zft 2 P23004 89.29 0.0 X-RAY
 2021-06-30 ARG B:150 B:169 172.0 0.764 S -94.4 -40.6 172.0 0.764 0.0
6zfu 2 P23004 89.29 0.0 X-RAY
 2021-06-30 ARG B:150 B:169 159.0 0.707 S -91.8 -31.6 159.0 0.707 0.0
6xvf 2 P23004 89.47 0.0 X-RAY
 2020-07-22 ARG B:148 B:169 167.0 0.742 S -89.0 -37.1 68.0 0.302 0.44 B:P23004:0.44
2bcc 2 ? 87.91 0.0 X-RAY
 1999-08-02 ARG B:152 B:169 52.0 NA S -140.4 73.8 52.0 NA NA
3bcc 2 P23004 87.91 0.0 X-RAY
 1998-08-19 ARG B:152 B:169 51.0 NA S -173.4 92.8 14.0 NA NA B:P23004:NA
6haw 2 P23004 88.28 0.0 X-RAY
 2019-01-16 ARG B:148 B:169 174.0 0.773 S -91.0 -34.8 174.0 0.773 0.0
1bcc 2 P23004 87.68 0.0 X-RAY
 1998-08-19 ARG B:152 B:169 73.0 NA S -126.7 -32.8 36.0 NA NA B:P23004:NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p22695-f1 1 P22695 100.0 0.0 ARG A:183 A:183 144.0 0.64 S -88.8 -23.3