Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 21983361 . C A CCDS10601.1:NM_003366.2:c.884gCt>gAt_NP_003357.2:p.295A>D Homo sapiens ubiquinol-cytochrome c reductase core protein II (UQCRC2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5xte 10 P22695 100.0 0.0 EM
 2017-08-30 ALA J:261 K:295 20.0 0.174 -64.9 -28.3 0.0 0.0 0.174 B:P47985:0.174
ALA U:261 W:295 26.0 0.226 S -64.6 -28.9 6.0 0.052 0.174 M:P47985:0.174
5xth 67 P22695 100.0 0.0 EM
 2017-09-13 ALA PB:261 AK:295 21.0 0.183 -64.9 -28.3 0.0 0.0 0.183 HB:P47985:0.183
ALA AC:261 AW:295 27.0 0.235 S -64.5 -29.0 6.0 0.052 0.183 SB:P47985:0.183
5xti 67 P22695 100.0 0.0 EM
 2017-09-13 ALA PB:261 AK:295 21.0 0.183 -64.9 -28.3 1.0 0.009 0.174 HB:P47985:0.174
ALA AC:261 AW:295 26.0 0.226 S -64.6 -29.0 5.0 0.043 0.183 SB:P47985:0.183
1sqb 2 P23004 89.4 0.0 X-RAY
 2004-09-07 ALA B:295 B:281 27.0 0.235 -94.7 -138.8 13.0 0.113 0.122 I:P13272:0.122
 HOH
 3.320
 N
 O
1sqp 2 P23004 89.4 0.0 X-RAY
 2005-11-01 ALA B:295 B:281 31.0 0.27 -88.8 -152.3 17.0 0.148 0.122 I:P13272:0.122
 HOH
 9.113
 O
 O
4d6t 2 P23004 89.4 0.0 X-RAY
 2015-01-14 ALA B:295 B:281 39.0 0.339 -117.3 -61.9 39.0 0.339 0.0
4d6u 2 P23004 89.4 0.0 X-RAY
 2015-01-14 ALA B:295 B:281 36.0 0.313 -95.2 -49.4 36.0 0.313 0.0
5okd 2 P23004 89.4 0.0 X-RAY
 2018-02-28 ALA B:295 B:281 33.0 0.287 -131.3 57.7 22.0 0.191 0.096 I:P13272:0.096
 HOH
 3.624
 O
 O
6fo6 3 P23004 89.4 0.0 EM
 2018-02-28 ALA C:295 B:281 39.0 0.339 S -102.5 37.5 39.0 0.339 0.0
ALA L:295 O:281 37.0 0.322 S -102.6 37.4 37.0 0.322 0.0
4d6t 10 P23004 89.18 0.0 X-RAY
 2015-01-14 ALA L:295 O:281 39.0 0.339 -113.7 -64.0 NA NA NA
4d6u 11 P23004 89.18 0.0 X-RAY
 2015-01-14 ALA L:295 O:281 36.0 0.313 -92.5 -48.5 NA NA NA
6fo0 2 P23004 89.18 0.0 EM
 2018-02-28 ALA B:295 O:281 29.0 0.252 -110.9 -26.0 29.0 0.252 0.0
ALA L:295 B:281 27.0 0.235 -111.0 -26.0 26.0 0.226 0.009 S:None:0.009
6fo2 2 P23004 89.18 0.0 EM
 2018-02-28 ALA B:295 O:281 33.0 0.287 -120.2 15.3 21.0 0.183 0.104 I:P13272:0.104
ALA L:295 B:281 34.0 0.296 -120.3 15.3 24.0 0.209 0.087 S:P13272:0.087
5gup 46 ? 88.3 0.0 EM
 2017-03-29 ALA VA:295 v:295 67.0 0.583 S -69.0 -25.1 26.0 0.226 0.357 PB:F1RNZ1:0.357
ALA GB:295 6:295 30.0 0.261 -143.4 65.4 17.0 0.148 0.113 OB:F1RNZ1:0.113
1be3 2 P23004 89.29 0.0 X-RAY
 1999-01-13 ALA B:281 B:281 3.0 0.026 -114.8 76.2 2.0 0.017 0.009 I:P13272:0.009
1bgy 2 P23004 89.29 0.0 X-RAY
 1999-01-06 ALA B:281 B:281 4.0 0.035 -112.8 70.6 3.0 0.026 0.009 I:P13272:0.009
ALA M:281 N:281 3.0 0.026 -113.9 67.6 3.0 0.026 0.0
1l0l 2 P23004 89.29 0.0 X-RAY
 2003-04-08 ALA B:281 B:281 37.0 0.322 -156.1 59.3 24.0 0.209 0.113 I:P13272:0.113
1l0n 2 P23004 89.29 0.0 X-RAY
 2003-04-08 ALA B:281 B:281 30.0 0.261 -100.4 -138.7 14.0 0.122 0.139 I:P13272:0.139
1ntk 2 P23004 89.29 0.0 X-RAY
 2003-10-07 ALA B:281 B:281 35.0 0.304 -154.0 74.7 35.0 0.304 0.0 HOH
 2.341
 N
 O
1ntm 2 P23004 89.29 0.0 X-RAY
 2003-10-07 ALA B:281 B:281 31.0 0.27 -111.3 -137.8 16.0 0.139 0.131 I:P13272:0.13
 HOH
 3.437
 N
 O
1ntz 2 P23004 89.29 0.0 X-RAY
 2003-10-07 ALA B:281 B:281 27.0 0.235 -99.4 -136.6 12.0 0.104 0.131 I:P13272:0.13
 HOH
 5.736
 CB
 O
1nu1 2 P23004 89.29 0.0 X-RAY
 2003-10-07 ALA B:281 B:281 33.0 0.287 -112.9 -129.0 16.0 0.139 0.148 I:P13272:0.148
1pp9 2 P23004 89.29 0.0 X-RAY
 2004-07-20 ALA B:281 B:281 34.0 0.296 -128.5 44.0 24.0 0.209 0.087 I:P13272:0.087
 HOH
 5.543
 O
 O
ALA L:281 O:281 36.0 0.313 -129.9 44.2 24.0 0.209 0.104 S:P13272:0.104
 HOH
 3.928
 N
 O
1ppj 2 P23004 89.29 0.0 X-RAY
 2004-07-20 ALA B:281 B:281 35.0 0.304 -120.4 23.7 21.0 0.183 0.121 I:P13272:0.122
 HOH
 6.907
 O
 O
ALA L:281 O:281 34.0 0.296 -121.4 23.4 19.0 0.165 0.131 S:P13272:0.13
 HOH
 7.143
 N
 O
1sqq 2 P23004 89.29 0.0 X-RAY
 2005-10-25 ALA B:281 B:281 34.0 0.296 -81.5 -147.9 18.0 0.157 0.139 I:P13272:0.139
1sqv 2 P23004 89.29 0.0 X-RAY
 2005-09-06 ALA B:281 B:281 28.0 0.243 -96.3 -133.6 14.0 0.122 0.121 I:P13272:0.122
 HOH
 4.887
 CB
 O
1sqx 2 P23004 89.29 0.0 X-RAY
 2005-09-06 ALA B:281 B:281 25.0 0.217 -93.6 -127.6 9.0 0.078 0.139 G:P13272:0.139
 HOH
 2.935
 N
 O
2a06 2 P23004 89.29 0.0 X-RAY
 2005-06-21 ALA B:281 B:281 35.0 0.304 -124.3 34.5 22.0 0.191 0.113 I:P13272:0.113
 PO4
HOH
 6.405
4.586
 CB
O
 O3
O
ALA L:281 O:281 34.0 0.296 -124.9 31.9 23.0 0.2 0.096 S:P13272:0.096
 UNL
UNL
UNL
HOH
 8.539
4.393
8.651
4.177
 O
O
O
N
 O2
O1
O1
O
2fyu 2 P23004 89.29 0.0 X-RAY
 2006-08-29 ALA B:281 B:281 27.0 0.235 -89.2 -129.0 9.0 0.078 0.157 I:P13272:0.157
 HOH
 5.734
 CB
 O
2ybb 10 P23004 89.29 0.0 EM
 2011-10-19 ALA J:281 B:281 35.0 0.304 -128.5 44.0 24.0 0.209 0.095 Q:P13272:0.096
 HOH
 5.543
 O
 O
ALA IA:281 b:281 34.0 0.296 -130.0 44.4 23.0 0.2 0.096 PA:P13272:0.096
 HOH
 3.927
 N
 O
5gpn 2 P23004 89.29 0.0 EM
 2017-04-05 ALA B:281 B:281 25.0 0.217 -112.9 70.7 15.0 0.13 0.087 I:P13272:0.087
ALA N:281 N:281 25.0 0.217 -113.9 67.6 10.0 0.087 0.13 U:P13272:0.13
5klv 2 P23004 89.29 0.0 X-RAY
 2016-10-12 ALA B:281 B:281 31.0 0.27 -91.3 -43.5 17.0 0.148 0.122 I:P13272:0.122
5luf 2 P23004 89.29 0.0 EM
 2016-11-30 ALA B:281 m:281 4.0 0.035 -112.8 70.6 3.0 0.026 0.009 I:P13272:0.009
ALA M:281 n:281 2.0 0.017 -113.9 67.6 2.0 0.017 0.0
6nhg 2 P23004 89.29 0.0 X-RAY
 2019-06-19 ALA B:281 B:281 27.0 0.235 -148.8 94.5 21.0 0.183 0.052 I:P13272:0.052
7o37 2 Q9DB77 85.42 0.0 EM
 2021-10-13 ALA B:281 B:281 38.0 0.33 -125.8 48.5 11.0 0.096 0.234 V:Q99KD6:0.104
U:Q9CR68:0.183
ALA L:281 M:281 36.0 0.313 -138.2 31.6 25.0 0.217 0.096 U:Q9CR68:0.096
7o3c 2 Q9DB77 85.42 0.0 EM
 2021-10-13 ALA B:281 B:281 37.0 0.322 -126.2 48.6 5.0 0.043 0.279 U:Q9CR68:0.209
V:Q99KD6:0.113
ALA L:281 M:281 39.0 0.339 -132.6 20.4 28.0 0.243 0.096 U:Q9CR68:0.096
7o3e 2 Q9DB77 85.42 0.0 EM
 2021-10-13 ALA B:281 B:281 38.0 0.33 -119.5 44.0 8.0 0.07 0.26 P:Q99KD6:0.043
O:Q9CR68:0.226
ALA I:281 M:281 37.0 0.322 -134.0 47.3 29.0 0.252 0.07 O:Q9CR68:0.07
7o3h 2 Q9DB77 85.42 0.0 EM
 2021-10-13 ALA B:281 B:281 41.0 0.357 -134.0 50.9 15.0 0.13 0.227 U:Q9CR68:0.226
ALA L:281 M:281 44.0 0.383 S -112.9 22.1 32.0 0.278 0.105 U:Q9CR68:0.104
6q9e 2 W5Q0F9 89.29 0.0 EM
 2019-08-21 ALA B:281 a2:281 32.0 0.278 -117.9 -166.7 32.0 0.278 0.0
ALA L:281 a4:281 41.0 0.357 -117.6 -166.5 40.0 0.348 0.009 S:None:0.009
6qbx 2 W5Q0F9 89.29 0.0 EM
 2019-08-21 ALA B:281 a2:281 35.0 0.304 -116.6 -167.9 35.0 0.304 0.0
ALA L:281 a4:281 32.0 0.278 -116.3 -164.3 28.0 0.243 0.035 S:None:0.035
6qc2 30 W5Q0F9 89.29 0.0 EM
 2019-08-21 ALA DA:281 a2:281 54.0 0.47 -127.6 -163.6 47.0 0.409 0.061 KA:None:0.061
ALA NA:281 a4:281 49.0 0.426 -114.7 -167.4 43.0 0.374 0.052 UA:None:0.052
6qc3 2 W5Q0F9 89.29 0.0 EM
 2019-08-21 ALA B:281 a2:281 31.0 0.27 -115.1 -164.6 22.0 0.191 0.079 I:None:0.078
ALA L:281 a4:281 29.0 0.252 -149.3 -163.3 29.0 0.252 0.0
6qc4 2 W5Q0F9 89.29 0.0 EM
 2019-08-21 ALA B:281 a2:281 35.0 0.304 -119.4 -170.1 35.0 0.304 0.0
ALA L:281 a4:281 39.0 0.339 -117.0 -170.6 39.0 0.339 0.0
5j4z 52 W5Q0F9 89.34 0.0 EM
 2016-09-21 ALA DB:265 AB:281 87.0 0.757 -158.0 -164.9 72.0 0.626 0.131 KB:W5P2X9:0.13
ALA OB:265 AM:281 86.0 0.748 -157.9 -164.9 71.0 0.617 0.131 VB:W5P2X9:0.13
5j7y 52 W5Q0F9 89.34 0.0 EM
 2016-09-21 ALA DB:265 AB:281 86.0 0.748 -158.0 -164.9 71.0 0.617 0.131 KB:W5P2X9:0.13
ALA OB:265 AM:281 85.0 0.739 -157.9 -165.0 71.0 0.617 0.122 VB:W5P2X9:0.122
5j8k 52 W5Q0F9 89.34 0.0 EM
 2016-09-21 ALA DB:265 AB:281 86.0 0.748 -158.1 -164.9 71.0 0.617 0.131 KB:W5P2X9:0.13
ALA OB:265 AM:281 86.0 0.748 -157.9 -164.9 71.0 0.617 0.131 VB:W5P2X9:0.13
5nmi 2 P23004 89.34 0.0 X-RAY
 2017-06-14 ALA B:265 B:281 30.0 0.261 -73.1 -60.2 20.0 0.174 0.087 I:P13272:0.087
ALA M:265 O:281 28.0 0.243 -73.0 -60.3 20.0 0.174 0.069 T:P13272:0.07
6zfs 2 P23004 89.29 0.0 X-RAY
 2021-06-30 ALA B:262 B:281 33.0 0.287 -126.1 64.4 23.0 0.2 0.087 I:P13272:0.087
6zft 2 P23004 89.29 0.0 X-RAY
 2021-06-30 ALA B:262 B:281 33.0 0.287 -115.7 69.0 28.0 0.243 0.044 I:P13272:0.043
6zfu 2 P23004 89.29 0.0 X-RAY
 2021-06-30 ALA B:262 B:281 31.0 0.27 -128.2 63.3 22.0 0.191 0.079 I:P13272:0.078
6xvf 2 P23004 89.47 0.0 X-RAY
 2020-07-22 ALA B:260 B:281 31.0 0.27 -125.0 58.4 21.0 0.183 0.087 I:P13272:0.087
2bcc 2 ? 87.91 0.0 X-RAY
 1999-08-02 ALA B:264 B:281 63.0 0.548 H -47.7 -24.8 40.0 0.348 0.2 I:None:0.026
A:None:0.183
3bcc 2 P23004 87.91 0.0 X-RAY
 1998-08-19 ALA B:264 B:281 62.0 0.539 H -54.7 -29.3 42.0 0.365 0.174 A:P31800:0.174
6haw 2 P23004 88.28 0.0 X-RAY
 2019-01-16 ALA B:255 B:281 31.0 0.27 -125.8 66.0 23.0 0.2 0.07 I:P13272:0.07
1bcc 2 P23004 87.68 0.0 X-RAY
 1998-08-19 ALA B:264 B:281 66.0 0.574 H -53.4 -35.9 47.0 0.409 0.165 I:None:0.017
A:P13272:0.148

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p22695-f1 1 P22695 100.0 0.0 ALA A:295 A:295 39.0 0.339 -87.8 8.2