Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 21991875 . C A CCDS10601.1:NM_003366.2:c.1132Ctg>Atg_NP_003357.2:p.378L>M Homo sapiens ubiquinol-cytochrome c reductase core protein II (UQCRC2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5xte 10 P22695 100.0 0.0 EM
 2017-08-30 LEU J:344 K:378 18.0 0.106 H -68.0 -36.8 17.0 0.1 0.006 B:P47985:0.006
LEU U:344 W:378 34.0 0.2 H -69.4 -36.9 18.0 0.106 0.094 M:P47985:0.094
5xth 67 P22695 100.0 0.0 EM
 2017-09-13 LEU PB:344 AK:378 19.0 0.112 H -68.0 -36.8 18.0 0.106 0.006 HB:P47985:0.006
LEU AC:344 AW:378 33.0 0.194 H -69.3 -36.9 18.0 0.106 0.088 SB:P47985:0.088
5xti 67 P22695 100.0 0.0 EM
 2017-09-13 LEU PB:344 AK:378 17.0 0.1 H -68.0 -36.8 16.0 0.094 0.006 HB:P47985:0.006
LEU AC:344 AW:378 33.0 0.194 H -69.3 -36.9 18.0 0.106 0.088 SB:P47985:0.088
1sqb 2 P23004 89.4 0.0 X-RAY
 2004-09-07 LEU B:378 B:364 23.0 0.135 H -66.9 -45.1 4.0 0.024 0.111 I:P13272:0.112
 HOH
 6.499
 N
 O
1sqp 2 P23004 89.4 0.0 X-RAY
 2005-11-01 LEU B:378 B:364 24.0 0.141 H -66.4 -50.8 5.0 0.029 0.112 I:P13272:0.112
 HOH
 8.784
 CD2
 O
4d6t 2 P23004 89.4 0.0 X-RAY
 2015-01-14 LEU B:378 B:364 25.0 0.147 H -64.0 -50.3 25.0 0.147 0.0
4d6u 2 P23004 89.4 0.0 X-RAY
 2015-01-14 LEU B:378 B:364 25.0 0.147 H -67.8 -47.6 25.0 0.147 0.0
5okd 2 P23004 89.4 0.0 X-RAY
 2018-02-28 LEU B:378 B:364 26.0 0.153 H -55.9 -48.1 26.0 0.153 0.0 HOH
 5.977
 N
 O
6fo6 3 P23004 89.4 0.0 EM
 2018-02-28 LEU C:378 B:364 23.0 0.135 H -65.3 -41.9 23.0 0.135 0.0
LEU L:378 O:364 22.0 0.129 H -65.2 -42.0 22.0 0.129 0.0
4d6t 10 P23004 89.18 0.0 X-RAY
 2015-01-14 LEU L:378 O:364 25.0 0.147 H -64.9 -48.8 NA NA NA
4d6u 11 P23004 89.18 0.0 X-RAY
 2015-01-14 LEU L:378 O:364 26.0 0.153 H -68.9 -46.4 NA NA NA
6fo0 2 P23004 89.18 0.0 EM
 2018-02-28 LEU B:378 O:364 24.0 0.141 H -62.8 -39.0 24.0 0.141 0.0
LEU L:378 B:364 25.0 0.147 H -62.9 -38.8 25.0 0.147 0.0
6fo2 2 P23004 89.18 0.0 EM
 2018-02-28 LEU B:378 O:364 24.0 0.141 H -63.1 -47.8 24.0 0.141 0.0
LEU L:378 B:364 24.0 0.141 H -63.1 -47.8 24.0 0.141 0.0
5gup 46 ? 88.3 0.0 EM
 2017-03-29 LEU VA:378 v:378 12.0 0.071 H -60.3 -51.0 7.0 0.041 0.03 PB:F1RNZ1:0.029
LEU GB:378 6:378 31.0 0.182 H -71.0 -30.7 16.0 0.094 0.088 OB:F1RNZ1:0.088
1be3 2 P23004 89.29 0.0 X-RAY
 1999-01-13 LEU B:364 B:364 22.0 0.129 H -50.0 -58.7 22.0 0.129 0.0
1bgy 2 P23004 89.29 0.0 X-RAY
 1999-01-06 LEU B:364 B:364 23.0 0.135 H -50.2 -55.1 23.0 0.135 0.0
LEU M:364 N:364 24.0 0.141 H -42.1 -60.6 24.0 0.141 0.0
1l0l 2 P23004 89.29 0.0 X-RAY
 2003-04-08 LEU B:364 B:364 25.0 0.147 H -60.8 -53.8 7.0 0.041 0.106 I:P13272:0.106
1l0n 2 P23004 89.29 0.0 X-RAY
 2003-04-08 LEU B:364 B:364 26.0 0.153 H -62.1 -48.6 6.0 0.035 0.118 I:P13272:0.118
1ntk 2 P23004 89.29 0.0 X-RAY
 2003-10-07 LEU B:364 B:364 22.0 0.129 H -52.6 -56.7 7.0 0.041 0.088 I:P13272:0.088
 HOH
 6.913
 CD2
 O
1ntm 2 P23004 89.29 0.0 X-RAY
 2003-10-07 LEU B:364 B:364 22.0 0.129 H -65.2 -59.8 3.0 0.018 0.111 I:P13272:0.112
 HOH
 4.050
 CD1
 O
1ntz 2 P23004 89.29 0.0 X-RAY
 2003-10-07 LEU B:364 B:364 25.0 0.147 H -63.0 -43.3 7.0 0.041 0.106 I:P13272:0.106
 HOH
 4.701
 CD1
 O
1nu1 2 P23004 89.29 0.0 X-RAY
 2003-10-07 LEU B:364 B:364 21.0 0.124 H -48.4 -59.4 5.0 0.029 0.095 I:P13272:0.094
1pp9 2 P23004 89.29 0.0 X-RAY
 2004-07-20 LEU B:364 B:364 23.0 0.135 H -56.8 -47.3 23.0 0.135 0.0 HOH
 6.800
 CD2
 O
LEU L:364 O:364 23.0 0.135 H -55.0 -47.1 23.0 0.135 0.0 HOH
 6.492
 CD2
 O
1ppj 2 P23004 89.29 0.0 X-RAY
 2004-07-20 LEU B:364 B:364 20.0 0.118 H -65.2 -46.8 20.0 0.118 0.0 HOH
 4.123
 CD1
 O
LEU L:364 O:364 23.0 0.135 H -64.8 -48.0 23.0 0.135 0.0 HOH
 7.814
 CD1
 O
1sqq 2 P23004 89.29 0.0 X-RAY
 2005-10-25 LEU B:364 B:364 22.0 0.129 H -65.5 -50.3 8.0 0.047 0.082 I:P13272:0.082
 HOH
 7.894
 CD2
 O
1sqv 2 P23004 89.29 0.0 X-RAY
 2005-09-06 LEU B:364 B:364 24.0 0.141 H -64.0 -55.1 5.0 0.029 0.112 I:P13272:0.112
 HOH
 4.887
 CD1
 O
1sqx 2 P23004 89.29 0.0 X-RAY
 2005-09-06 LEU B:364 B:364 20.0 0.118 H -66.1 -46.0 4.0 0.024 0.094 G:P13272:0.094
 HOH
 5.141
 N
 O
2a06 2 P23004 89.29 0.0 X-RAY
 2005-06-21 LEU B:364 B:364 20.0 0.118 H -61.6 -47.9 20.0 0.118 0.0 PO4
HOH
 6.342
4.206
 CD1
CD1
 O3
O
LEU L:364 O:364 22.0 0.129 H -61.0 -50.1 22.0 0.129 0.0 UNL
UNL
UNL
HOH
 9.399
5.926
9.438
6.486
 O
N
CD1
CD2
 O2
O1
O1
O
2fyu 2 P23004 89.29 0.0 X-RAY
 2006-08-29 LEU B:364 B:364 26.0 0.153 H -56.9 -50.8 4.0 0.024 0.129 I:P13272:0.129
 HOH
 4.264
 CD1
 O
2ybb 10 P23004 89.29 0.0 EM
 2011-10-19 LEU J:364 B:364 22.0 0.129 H -56.7 -47.4 22.0 0.129 0.0 HOH
 6.799
 CD2
 O
LEU IA:364 b:364 24.0 0.141 H -55.0 -47.1 24.0 0.141 0.0 HOH
 6.492
 CD2
 O
5gpn 2 P23004 89.29 0.0 EM
 2017-04-05 LEU B:364 B:364 42.0 NA H -50.0 -55.2 42.0 NA NA
LEU N:364 N:364 42.0 NA H -42.2 -60.5 42.0 NA NA
5klv 2 P23004 89.29 0.0 X-RAY
 2016-10-12 LEU B:364 B:364 25.0 0.147 H -63.6 -43.9 25.0 0.147 0.0 HOH
 9.902
 HD21
 O
5luf 2 P23004 89.29 0.0 EM
 2016-11-30 LEU B:364 m:364 23.0 0.135 H -50.2 -55.1 23.0 0.135 0.0
LEU M:364 n:364 24.0 0.141 H -42.1 -60.7 24.0 0.141 0.0
6nhg 2 P23004 89.29 0.0 X-RAY
 2019-06-19 LEU B:364 B:364 25.0 0.147 H -67.0 -52.6 25.0 0.147 0.0 HOH
 8.105
 HD21
 O
7o37 2 Q9DB77 85.42 0.0 EM
 2021-10-13 LEU B:364 B:364 19.0 0.112 H -68.7 -41.5 1.0 0.006 0.106 U:Q9CR68:0.106
LEU L:364 M:364 23.0 0.135 H -67.9 -41.2 23.0 0.135 0.0
7o3c 2 Q9DB77 85.42 0.0 EM
 2021-10-13 LEU B:364 B:364 24.0 0.141 H -66.3 -44.0 8.0 0.047 0.094 U:Q9CR68:0.094
LEU L:364 M:364 22.0 0.129 H -68.5 -47.6 22.0 0.129 0.0
7o3e 2 Q9DB77 85.42 0.0 EM
 2021-10-13 LEU B:364 B:364 16.0 0.094 H -66.9 -41.8 2.0 0.012 0.082 O:Q9CR68:0.082
LEU I:364 M:364 21.0 0.124 H -66.4 -41.3 21.0 0.124 0.0
7o3h 2 Q9DB77 85.42 0.0 EM
 2021-10-13 LEU B:364 B:364 21.0 0.124 H -65.7 -43.3 1.0 0.006 0.118 U:Q9CR68:0.118
LEU L:364 M:364 23.0 0.135 H -66.6 -42.6 23.0 0.135 0.0
6q9e 2 W5Q0F9 89.29 0.0 EM
 2019-08-21 LEU B:364 a2:364 22.0 0.129 H -72.3 -38.8 22.0 0.129 0.0
LEU L:364 a4:364 18.0 0.106 H -71.9 -37.6 11.0 0.065 0.041 S:None:0.041
6qbx 2 W5Q0F9 89.29 0.0 EM
 2019-08-21 LEU B:364 a2:364 20.0 0.118 H -67.0 -34.3 20.0 0.118 0.0
LEU L:364 a4:364 23.0 0.135 H -69.3 -39.2 21.0 0.124 0.011 S:None:0.012
6qc2 30 W5Q0F9 89.29 0.0 EM
 2019-08-21 LEU DA:364 a2:364 23.0 0.135 H -71.8 -36.9 23.0 0.135 0.0
LEU NA:364 a4:364 22.0 0.129 H -70.5 -40.9 22.0 0.129 0.0
6qc3 2 W5Q0F9 89.29 0.0 EM
 2019-08-21 LEU B:364 a2:364 26.0 0.153 H -70.4 -30.0 26.0 0.153 0.0
LEU L:364 a4:364 21.0 0.124 H -71.1 -35.5 8.0 0.047 0.077 S:None:0.076
6qc4 2 W5Q0F9 89.29 0.0 EM
 2019-08-21 LEU B:364 a2:364 24.0 0.141 H -68.8 -42.5 24.0 0.141 0.0
LEU L:364 a4:364 16.0 0.094 H -73.2 -40.2 7.0 0.041 0.053 S:None:0.053
5j4z 52 W5Q0F9 89.34 0.0 EM
 2016-09-21 LEU DB:348 AB:364 38.0 NA I -69.8 -46.3 38.0 NA NA
LEU OB:348 AM:364 38.0 NA I -69.7 -46.2 38.0 NA NA
5j7y 52 W5Q0F9 89.34 0.0 EM
 2016-09-21 LEU DB:348 AB:364 39.0 NA I -69.8 -46.3 39.0 NA NA
LEU OB:348 AM:364 37.0 NA I -69.7 -46.2 37.0 NA NA
5j8k 52 W5Q0F9 89.34 0.0 EM
 2016-09-21 LEU DB:348 AB:364 38.0 NA I -69.8 -46.2 38.0 NA NA
LEU OB:348 AM:364 37.0 NA I -69.6 -46.3 37.0 NA NA
5nmi 2 P23004 89.34 0.0 X-RAY
 2017-06-14 LEU B:348 B:364 19.0 0.112 H -64.8 -54.0 19.0 0.112 0.0
LEU M:348 O:364 18.0 0.106 H -64.9 -53.8 18.0 0.106 0.0
6zfs 2 P23004 89.29 0.0 X-RAY
 2021-06-30 LEU B:345 B:364 27.0 0.159 H -58.3 -44.6 27.0 0.159 0.0
6zft 2 P23004 89.29 0.0 X-RAY
 2021-06-30 LEU B:345 B:364 28.0 0.165 H -59.5 -50.7 28.0 0.165 0.0
6zfu 2 P23004 89.29 0.0 X-RAY
 2021-06-30 LEU B:345 B:364 28.0 0.165 H -58.0 -44.6 28.0 0.165 0.0
6xvf 2 P23004 89.47 0.0 X-RAY
 2020-07-22 LEU B:343 B:364 28.0 0.165 H -57.8 -44.7 28.0 0.165 0.0 HOH
 9.823
 CD1
 O
2bcc 2 ? 87.91 0.0 X-RAY
 1999-08-02 LEU B:347 B:364 27.0 0.159 H -55.3 -43.7 27.0 0.159 0.0
3bcc 2 P23004 87.91 0.0 X-RAY
 1998-08-19 LEU B:347 B:364 28.0 0.165 H -64.8 -41.7 28.0 0.165 0.0
6haw 2 P23004 88.28 0.0 X-RAY
 2019-01-16 LEU B:338 B:364 29.0 0.171 H -58.9 -43.8 29.0 0.171 0.0 PG4
 4.473
 CD1
 O5
1bcc 2 P23004 87.68 0.0 X-RAY
 1998-08-19 LEU B:347 B:364 27.0 0.159 H -60.7 -49.8 27.0 0.159 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p22695-f1 1 P22695 100.0 0.0 LEU A:378 A:378 25.0 0.147 H -62.4 -47.8