Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 30490748 . A C CCDS32433.1:NM_002209.2:c.542gAt>gCt_NP_002200.2:p.181D>A Homo sapiens integrin subunit alpha L (ITGAL), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5e6r 1 P20701 99.6 0.0 X-RAY
 2016-03-02 ASP A:156 A:156 52.0 0.347 H -61.4 -35.0 52.0 0.347 0.0 HOH
 2.504
 OD1
 O
5e6s 1 P20701 99.6 0.0 X-RAY
 2016-03-02 ASP A:156 A:156 59.0 0.393 H -65.2 -33.2 59.0 0.393 0.0 HOH
 9.868
 OD2
 O
ASP C:156 C:156 49.0 0.327 H -74.0 -29.0 NA NA NA
ASP E:156 E:156 56.0 0.373 H -68.4 -36.5 NA NA NA
5e6u 1 P20701 99.6 0.0 X-RAY
 2016-04-06 ASP A:156 A:156 58.0 0.387 H -64.2 -34.5 58.0 0.387 0.0 HOH
 7.138
 O
 O
7kc3 1 P20701 98.98 1e-132 X-RAY
 2021-10-06 ASP A:36 C:156 42.0 0.28 H -57.3 -44.4 42.0 0.28 0.0 HOH
 2.642
 O
 O
1rd4 1 P20701 98.43 4e-128 X-RAY
 2004-03-30 ASP A:36 A:156 71.0 0.473 H -60.6 -38.7 71.0 0.473 0.0 L08
 7.662
 C
 O4
ASP B:36 B:156 60.0 0.4 H -57.4 -44.7 NA NA NA
ASP C:36 C:156 61.0 0.407 H -58.0 -42.1 NA NA NA
ASP D:36 D:156 61.0 0.407 H -56.6 -44.2 NA NA NA
1lfa 1 P20701 100.0 7e-128 X-RAY
 1996-01-29 ASP A:32 A:156 58.0 0.387 H -61.7 -47.0 58.0 0.387 0.0 HOH
 1.921
 OD1
 H2
ASP B:32 B:156 17.0 0.113 H -53.8 -55.5 17.0 0.113 0.0 HOH
 1.908
 O
 H2
1zon 1 P20701 100.0 7e-128 X-RAY
 1996-12-07 ASP A:32 A:156 50.0 0.333 H -59.2 -48.6 50.0 0.333 0.0 HOH
 1.997
 OD1
 H1
1zoo 1 P20701 100.0 7e-128 X-RAY
 1996-12-07 ASP A:32 A:156 50.0 0.333 H -56.8 -48.1 50.0 0.333 0.0
ASP B:32 B:156 55.0 0.367 H -59.6 -45.6 55.0 0.367 0.0
1zop 1 P20701 100.0 7e-128 X-RAY
 1996-12-07 ASP A:32 A:156 51.0 0.34 H -56.7 -48.1 51.0 0.34 0.0 HOH
 1.861
 O
 H2
ASP B:32 B:156 53.0 0.353 H -59.6 -45.6 53.0 0.353 0.0 HOH
 1.914
 O
 H1
1dgq 1 P20701 99.46 1e-124 NMR
 2000-02-03 ASP A:33 A:156 20.0 0.133 H -59.2 -57.0 20.0 0.133 0.0
1xdd 1 P20701 99.46 1e-124 X-RAY
 2004-09-21 ASP A:33 A:156 40.0 0.267 H -62.4 -47.4 40.0 0.267 0.0 AAY
HOH
 8.479
2.706
 C
OD1
 C36
O
ASP B:33 B:156 59.0 0.393 H -56.3 -49.0 NA NA NA
1xdg 1 P20701 99.46 1e-124 X-RAY
 2004-09-21 ASP A:33 A:156 68.0 0.453 H -57.4 -44.2 68.0 0.453 0.0 AB8
HOH
 9.110
2.790
 C
OD2
 C32
O
ASP B:33 B:156 42.0 0.28 H -61.2 -44.2 NA NA NA
1xuo 1 P20701 99.46 1e-124 X-RAY
 2005-10-26 ASP A:33 A:156 58.0 0.387 H -60.5 -41.7 58.0 0.387 0.0 LA1
HOH
 8.542
2.782
 C
OD1
 C19
O
ASP B:33 B:156 69.0 0.46 H -61.2 -47.5 NA NA NA
4ixd 1 P20701 99.46 1e-124 X-RAY
 2014-01-29 ASP A:33 A:156 35.0 0.233 H -57.1 -47.0 35.0 0.233 0.0 HOH
 2.683
 OD1
 O
7kc5 1 P20701 100.0 3e-123 X-RAY
 2021-10-06 ASP A:31 A:156 47.0 0.313 H -57.9 -45.7 47.0 0.313 0.0 BJZ
HOH
 6.042
2.755
 O
O
 N37
O
ASP B:31 C:156 57.0 0.38 H -62.2 -42.2 NA NA NA
7kc6 1 P20701 100.0 3e-123 X-RAY
 2021-10-06 ASP A:31 C:156 29.0 0.193 H -61.4 -45.4 29.0 0.193 0.0 803
HOH
 8.300
2.488
 C
OD1
 H5
O
ASP B:31 A:156 54.0 0.36 H -54.4 -48.7 NA NA NA
3e2m 1 P20701 99.45 6e-123 X-RAY
 2008-08-19 ASP A:32 A:156 60.0 0.4 H -55.8 -44.7 60.0 0.4 0.0 E2M
HOH
 7.610
2.628
 C
OD1
 F3
O
ASP B:32 B:156 64.0 0.427 H -48.1 -50.7 64.0 0.427 0.0 E2M
HOH
 7.609
2.870
 C
O
 F3
O
3eoa 3 P20701 100.0 8e-123 X-RAY
 2009-04-14 ASP E:29 I:156 47.0 0.313 H -52.4 -39.5 47.0 0.313 0.0 HOH
 2.738
 OD1
 O
ASP F:29 J:156 57.0 0.38 H -59.6 -47.3 NA NA NA
3eob 3 P20701 100.0 8e-123 X-RAY
 2009-04-14 ASP C:29 I:156 48.0 0.32 H -75.4 -28.4 48.0 0.32 0.0
ASP F:29 J:156 56.0 0.373 H -70.5 -20.6 NA NA NA
1cqp 1 P20701 99.45 2e-122 X-RAY
 2000-08-07 ASP A:29 A:156 65.0 0.433 H -59.8 -59.3 65.0 0.433 0.0 803
HOH
 9.051
2.952
 C
OD1
 C5
O
ASP B:29 B:156 38.0 0.253 H -54.7 -46.2 NA NA NA
3bqm 1 P20701 99.45 2e-122 X-RAY
 2008-08-19 ASP A:29 B:156 59.0 0.393 H -52.8 -48.5 59.0 0.393 0.0 BQM
HOH
 7.628
2.614
 C
O
 F2
O
ASP B:29 C:156 63.0 0.42 H -58.0 -43.2 NA NA NA
3bqn 1 P20701 99.45 2e-122 X-RAY
 2008-08-19 ASP A:29 B:156 62.0 0.413 H -59.6 -45.2 62.0 0.413 0.0 BQN
HOH
 7.591
2.742
 C
O
 F2
O
ASP B:29 C:156 65.0 0.433 H -59.2 -44.2 NA NA NA
2ica 1 P20701 100.0 3e-121 X-RAY
 2006-12-19 ASP A:32 A:156 47.0 0.313 H -57.7 -46.8 47.0 0.313 0.0 2IC
HOH
 5.856
2.770
 O
OD1
 N35
O
2o7n 1 P20701 100.0 3e-121 X-RAY
 2007-03-20 ASP A:32 A:156 69.0 0.46 H -61.7 -40.7 69.0 0.46 0.0 2O7
HOH
 7.709
2.689
 O
OD2
 N43
O
3m6f 1 P20701 100.0 3e-121 X-RAY
 2010-05-12 ASP A:32 A:156 56.0 0.373 H -58.2 -49.2 56.0 0.373 0.0 BJZ
HOH
 6.065
2.728
 O
OD1
 N37
O
3f74 1 P20701 99.44 5e-121 X-RAY
 2009-06-23 ASP A:30 A:156 35.0 0.233 H -60.5 -44.4 35.0 0.233 0.0 HOH
 2.597
 OD2
 O
ASP B:30 B:156 47.0 0.313 H -67.3 -43.6 NA NA NA
ASP C:30 C:156 43.0 0.287 H -64.5 -43.6 NA NA NA
3f78 1 P20701 99.44 5e-121 X-RAY
 2009-06-23 ASP A:30 A:156 42.0 0.28 H -64.3 -42.5 42.0 0.28 0.0 HOH
 2.725
 OD2
 O
ASP B:30 B:156 38.0 0.253 H -65.8 -42.0 NA NA NA
ASP C:30 C:156 46.0 0.307 H -64.0 -43.6 NA NA NA
3hi6 1 P20701 98.33 3e-119 X-RAY
 2009-09-22 ASP A:29 A:156 68.0 0.453 H -61.6 -47.3 NA NA NA
ASP B:29 B:156 80.0 0.533 H -60.6 -43.1 80.0 0.533 0.0 HOH
 3.043
 OD1
 O
1mjn 1 P20701 98.88 3e-119 X-RAY
 2003-01-28 ASP A:29 A:156 68.0 0.453 H -66.5 -43.3 68.0 0.453 0.0 HOH
 2.432
 OD1
 O
1mq9 1 P20701 98.88 6e-119 X-RAY
 2003-01-14 ASP A:30 A:156 33.0 0.22 H -62.4 -45.9 33.0 0.22 0.0 HOH
 2.761
 OD2
 O
1mqa 1 P20701 98.88 6e-119 X-RAY
 2003-01-14 ASP A:30 A:156 73.0 0.487 H -63.9 -37.3 73.0 0.487 0.0 HOH
 3.094
 OD1
 O
3tcx 2 P20701 98.88 7e-119 X-RAY
 2011-08-31 ASP B:29 B:156 51.0 0.34 H -69.0 -33.2 51.0 0.34 0.0
ASP D:29 D:156 52.0 0.347 H -69.9 -34.9 NA NA NA
ASP F:29 F:156 53.0 0.353 H -68.6 -35.5 NA NA NA
ASP H:29 H:156 51.0 0.34 H -69.1 -34.3 NA NA NA
ASP J:29 J:156 52.0 0.347 H -68.3 -35.1 NA NA NA
ASP L:29 L:156 52.0 0.347 H -70.2 -34.5 NA NA NA
ASP N:29 N:156 53.0 0.353 H -68.0 -34.8 NA NA NA
ASP P:29 P:156 52.0 0.347 H -68.2 -35.0 NA NA NA
ASP R:29 R:156 52.0 0.347 H -69.2 -33.7 NA NA NA
ASP T:29 T:156 52.0 0.347 H -69.2 -33.4 NA NA NA
ASP V:29 V:156 54.0 0.36 H -68.5 -34.9 NA NA NA
ASP X:29 X:156 53.0 0.353 H -69.0 -33.3 NA NA NA
ASP Z:29 Z:156 53.0 0.353 H -68.0 -35.5 NA NA NA
ASP BA:29 b:156 52.0 0.347 H -68.8 -34.4 NA NA NA
1mq8 2 P20701 98.87 2e-117 X-RAY
 2003-01-14 ASP B:27 B:156 16.0 0.107 H -60.8 -22.1 16.0 0.107 0.0
ASP D:27 D:156 17.0 0.113 H -60.9 -21.8 NA NA NA
3bn3 1 P20701 98.32 2e-117 X-RAY
 2008-08-19 ASP A:29 A:156 82.0 0.547 H -63.3 -44.8 82.0 0.547 0.0 HOH
 2.696
 OD2
 O
6bxb 1 P05106,P20701 99.44 4e-113 X-RAY
 2018-08-01 ASP A:138 A:138 95.0 0.633 H -57.7 -51.1 95.0 0.633 0.0 HOH
 8.729
 OD1
 O
ASP B:138 B:138 59.0 0.393 H -59.5 -35.0 NA NA NA
6ckb 1 P05106,P20701 99.44 4e-113 X-RAY
 2018-08-01 ASP A:138 A:138 70.0 0.467 H -63.1 -41.4 70.0 0.467 0.0
ASP B:138 B:138 96.0 0.64 H -70.0 -30.1 NA NA NA
6bxf 1 P05106,P20701 99.44 5e-113 X-RAY
 2018-08-01 ASP A:138 A:138 90.0 0.6 H -63.7 -38.3 90.0 0.6 0.0
ASP B:138 B:138 77.0 0.513 H -67.2 -30.4 NA NA NA
6bxj 1 P05106,P20701 99.44 8e-112 X-RAY
 2018-10-03 ASP A:138 A:138 44.0 0.293 H -65.0 -43.3 44.0 0.293 0.0 HOH
 3.099
 OD2
 O
1t0p 1 P20701 98.28 3e-111 X-RAY
 2005-03-08 ASP A:30 A:156 69.0 0.46 H -67.3 -44.6 69.0 0.46 0.0 HOH
 2.805
 OD1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p20701-f1 1 P20701 100.0 0.0 ASP A:181 A:181 66.0 0.44 H -66.5 -38.4