Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 30492796 . G A CCDS32433.1:NM_002209.2:c.613Gaa>Aaa_NP_002200.2:p.205E>K Homo sapiens integrin subunit alpha L (ITGAL), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5e6r 1 P20701 99.6 0.0 X-RAY
 2016-03-02 GLU A:180 A:180 23.0 0.121 E -75.9 -33.5 23.0 0.121 0.0 HOH
 3.338
 OE2
 O
5e6s 1 P20701 99.6 0.0 X-RAY
 2016-03-02 GLU A:180 A:180 26.0 0.137 E -77.9 -31.6 26.0 0.137 0.0 HOH
 2.448
 OE1
 O
GLU C:180 C:180 25.0 0.132 E -74.4 -36.0 NA NA NA
GLU E:180 E:180 24.0 0.126 E -74.7 -32.0 NA NA NA
5e6u 1 P20701 99.6 0.0 X-RAY
 2016-04-06 GLU A:180 A:180 24.0 0.126 E -80.2 -25.9 24.0 0.126 0.0 HOH
 3.014
 OE2
 O
7kc3 1 P20701 98.98 1e-132 X-RAY
 2021-10-06 GLU A:60 C:180 26.0 0.137 E -75.6 -34.8 26.0 0.137 0.0 HOH
 2.592
 OE2
 O
1rd4 1 P20701 98.43 4e-128 X-RAY
 2004-03-30 GLU A:60 A:180 24.0 0.126 E -60.7 -35.7 24.0 0.126 0.0
GLU B:60 B:180 25.0 0.132 E -63.2 -32.1 NA NA NA
GLU C:60 C:180 23.0 0.121 E -63.1 -30.4 NA NA NA
GLU D:60 D:180 24.0 0.126 E -63.5 -32.0 NA NA NA
1lfa 1 P20701 100.0 7e-128 X-RAY
 1996-01-29 GLU A:56 A:180 23.0 0.121 E -65.9 -32.9 23.0 0.121 0.0 HOH
 1.954
 OE1
 H2
GLU B:56 B:180 25.0 0.132 E -72.8 -31.3 25.0 0.132 0.0 HOH
 1.878
 OE2
 H2
1zon 1 P20701 100.0 7e-128 X-RAY
 1996-12-07 GLU A:56 A:180 28.0 0.147 E -68.5 -37.1 28.0 0.147 0.0 HOH
 1.936
 O
 H2
1zoo 1 P20701 100.0 7e-128 X-RAY
 1996-12-07 GLU A:56 A:180 24.0 0.126 E -72.2 -29.7 24.0 0.126 0.0
GLU B:56 B:180 27.0 0.142 E -77.2 -26.4 27.0 0.142 0.0
1zop 1 P20701 100.0 7e-128 X-RAY
 1996-12-07 GLU A:56 A:180 10.0 0.053 E -72.2 -29.7 10.0 0.053 0.0 HOH
 2.029
 OE2
 H2
GLU B:56 B:180 28.0 0.147 E -77.2 -26.4 28.0 0.147 0.0 HOH
 1.882
 OE1
 H2
1dgq 1 P20701 99.46 1e-124 NMR
 2000-02-03 GLU A:57 A:180 8.0 0.042 E -70.9 -47.8 8.0 0.042 0.0
1xdd 1 P20701 99.46 1e-124 X-RAY
 2004-09-21 GLU A:57 A:180 26.0 0.137 E -73.5 -40.1 26.0 0.137 0.0 HOH
 2.648
 OE2
 O
GLU B:57 B:180 24.0 0.126 E -79.2 -35.6 NA NA NA
1xdg 1 P20701 99.46 1e-124 X-RAY
 2004-09-21 GLU A:57 A:180 26.0 0.137 E -81.3 -33.9 26.0 0.137 0.0 HOH
 2.667
 OE1
 O
GLU B:57 B:180 28.0 0.147 E -79.0 -32.1 NA NA NA
1xuo 1 P20701 99.46 1e-124 X-RAY
 2005-10-26 GLU A:57 A:180 28.0 0.147 E -81.5 -36.8 28.0 0.147 0.0 HOH
 2.692
 OE1
 O
GLU B:57 B:180 25.0 0.132 E -79.8 -39.4 NA NA NA
4ixd 1 P20701 99.46 1e-124 X-RAY
 2014-01-29 GLU A:57 A:180 24.0 0.126 E -67.9 -37.2 24.0 0.126 0.0 HOH
 2.677
 OE2
 O
7kc5 1 P20701 100.0 3e-123 X-RAY
 2021-10-06 GLU A:55 A:180 24.0 0.126 E -77.0 -35.5 24.0 0.126 0.0 HOH
 2.682
 OE1
 O
GLU B:55 C:180 29.0 0.153 E -80.3 -37.8 NA NA NA
7kc6 1 P20701 100.0 3e-123 X-RAY
 2021-10-06 GLU A:55 C:180 25.0 0.132 E -76.7 -37.5 25.0 0.132 0.0 HOH
 2.809
 OE1
 O
GLU B:55 A:180 27.0 0.142 E -82.1 -39.1 NA NA NA
3e2m 1 P20701 99.45 6e-123 X-RAY
 2008-08-19 GLU A:56 A:180 28.0 0.147 E -72.3 -40.6 28.0 0.147 0.0 HOH
 2.624
 OE1
 O
GLU B:56 B:180 24.0 0.126 E -71.0 -33.8 24.0 0.126 0.0 HOH
 2.599
 OE1
 O
3eoa 3 P20701 100.0 8e-123 X-RAY
 2009-04-14 GLU E:53 I:180 27.0 0.142 E -75.2 -36.9 27.0 0.142 0.0 HOH
 3.883
 O
 O
GLU F:53 J:180 26.0 0.137 E -70.3 -42.3 NA NA NA
3eob 3 P20701 100.0 8e-123 X-RAY
 2009-04-14 GLU C:53 I:180 21.0 0.111 E -68.3 -16.6 21.0 0.111 0.0
GLU F:53 J:180 28.0 0.147 E -71.6 -41.3 NA NA NA
1cqp 1 P20701 99.45 2e-122 X-RAY
 2000-08-07 GLU A:53 A:180 27.0 0.142 E -70.6 -28.4 27.0 0.142 0.0 HOH
 2.754
 O
 O
GLU B:53 B:180 29.0 0.153 E -73.1 -30.7 NA NA NA
3bqm 1 P20701 99.45 2e-122 X-RAY
 2008-08-19 GLU A:53 B:180 26.0 0.137 E -74.4 -41.2 26.0 0.137 0.0 HOH
 2.703
 OE1
 O
GLU B:53 C:180 24.0 0.126 E -70.5 -38.5 NA NA NA
3bqn 1 P20701 99.45 2e-122 X-RAY
 2008-08-19 GLU A:53 B:180 26.0 0.137 E -72.5 -41.0 26.0 0.137 0.0 HOH
 2.633
 OE2
 O
GLU B:53 C:180 24.0 0.126 E -72.2 -39.4 NA NA NA
2ica 1 P20701 100.0 3e-121 X-RAY
 2006-12-19 GLU A:56 A:180 27.0 0.142 E -81.2 -40.3 27.0 0.142 0.0 HOH
 2.694
 OE1
 O
2o7n 1 P20701 100.0 3e-121 X-RAY
 2007-03-20 GLU A:56 A:180 26.0 0.137 E -68.6 -38.2 26.0 0.137 0.0 HOH
 2.626
 OE1
 O
3m6f 1 P20701 100.0 3e-121 X-RAY
 2010-05-12 GLU A:56 A:180 31.0 0.163 E -84.7 -38.5 31.0 0.163 0.0 HOH
 2.581
 OE1
 O
3f74 1 P20701 99.44 5e-121 X-RAY
 2009-06-23 GLU A:54 A:180 25.0 0.132 E -76.0 -37.2 25.0 0.132 0.0 HOH
 2.660
 OE1
 O
GLU B:54 B:180 28.0 0.147 E -82.2 -36.6 NA NA NA
GLU C:54 C:180 27.0 0.142 E -83.0 -35.3 NA NA NA
3f78 1 P20701 99.44 5e-121 X-RAY
 2009-06-23 GLU A:54 A:180 23.0 0.121 E -79.3 -35.9 23.0 0.121 0.0 HOH
 2.669
 OE2
 O
GLU B:54 B:180 26.0 0.137 E -78.9 -36.6 NA NA NA
GLU C:54 C:180 27.0 0.142 E -83.3 -36.6 NA NA NA
3hi6 1 P20701 98.33 3e-119 X-RAY
 2009-09-22 GLU A:53 A:180 28.0 0.147 E -80.1 -36.7 NA NA NA
GLU B:53 B:180 27.0 0.142 E -75.3 -36.7 27.0 0.142 0.0 HOH
 2.679
 OE1
 O
1mjn 1 P20701 98.88 3e-119 X-RAY
 2003-01-28 GLU A:53 A:180 23.0 0.121 E -76.3 -36.1 23.0 0.121 0.0 HOH
 2.669
 OE2
 O
1mq9 1 P20701 98.88 6e-119 X-RAY
 2003-01-14 GLU A:54 A:180 26.0 0.137 E -75.4 -36.2 26.0 0.137 0.0 HOH
 2.723
 OE2
 O
1mqa 1 P20701 98.88 6e-119 X-RAY
 2003-01-14 GLU A:54 A:180 8.0 0.042 E -62.0 -34.4 8.0 0.042 0.0 HOH
 3.049
 OE1
 O
3tcx 2 P20701 98.88 7e-119 X-RAY
 2011-08-31 GLU B:53 B:180 29.0 0.153 E -82.9 -29.9 29.0 0.153 0.0
GLU D:53 D:180 30.0 0.158 E -79.3 -29.0 NA NA NA
GLU F:53 F:180 30.0 0.158 E -79.2 -27.6 NA NA NA
GLU H:53 H:180 30.0 0.158 E -81.7 -27.4 NA NA NA
GLU J:53 J:180 30.0 0.158 E -80.5 -27.7 NA NA NA
GLU L:53 L:180 29.0 0.153 E -84.6 -27.1 NA NA NA
GLU N:53 N:180 30.0 0.158 E -81.1 -27.7 NA NA NA
GLU P:53 P:180 29.0 0.153 E -80.1 -28.2 NA NA NA
GLU R:53 R:180 29.0 0.153 E -80.1 -26.1 NA NA NA
GLU T:53 T:180 31.0 0.163 E -81.7 -28.0 NA NA NA
GLU V:53 V:180 30.0 0.158 E -77.7 -25.7 NA NA NA
GLU X:53 X:180 31.0 0.163 E -79.7 -27.9 NA NA NA
GLU Z:53 Z:180 31.0 0.163 E -81.3 -27.0 NA NA NA
GLU BA:53 b:180 30.0 0.158 E -80.2 -26.9 NA NA NA
1mq8 2 P20701 98.87 2e-117 X-RAY
 2003-01-14 GLU B:51 B:180 23.0 0.121 E -56.4 -51.7 23.0 0.121 0.0
GLU D:51 D:180 21.0 0.111 E -56.5 -51.6 NA NA NA
3bn3 1 P20701 98.32 2e-117 X-RAY
 2008-08-19 GLU A:53 A:180 30.0 0.158 E -77.6 -34.5 30.0 0.158 0.0 HOH
 2.579
 OE2
 O
6bxb 1 P05106,P20701 99.44 4e-113 X-RAY
 2018-08-01 GLU A:162 A:162 26.0 0.137 E -81.8 -34.6 26.0 0.137 0.0 HOH
 2.761
 OE1
 O
GLU B:162 B:162 38.0 0.2 -60.0 -83.8 NA NA NA
6ckb 1 P05106,P20701 99.44 4e-113 X-RAY
 2018-08-01 GLU A:162 A:162 18.0 0.095 E -74.5 -26.1 18.0 0.095 0.0
GLU B:162 B:162 50.0 0.263 51.3 -71.1 NA NA NA
6bxf 1 P05106,P20701 99.44 5e-113 X-RAY
 2018-08-01 GLU A:162 A:162 22.0 0.116 E -77.5 -31.3 22.0 0.116 0.0
GLU B:162 B:162 22.0 0.116 S -64.7 -38.0 NA NA NA
6bxj 1 P05106,P20701 99.44 8e-112 X-RAY
 2018-10-03 GLU A:162 A:162 26.0 0.137 E -76.8 -35.0 26.0 0.137 0.0 MG
HOH
 9.007
2.729
 O
OE2
 MG
O
1t0p 1 P20701 98.28 3e-111 X-RAY
 2005-03-08 GLU A:54 A:180 14.0 0.074 E -71.4 -31.8 14.0 0.074 0.0 HOH
 2.758
 OE2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p20701-f1 1 P20701 100.0 0.0 GLU A:205 A:205 30.0 0.158 E -87.9 -32.2