Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr16 | 30495176 | . | G | A | CCDS32433.1:NM_002209.2:c.751Gcc>Acc_NP_002200.2:p.251A>T | Homo sapiens integrin subunit alpha L (ITGAL), transcript variant 1, mRNA. |
---|---|---|---|---|---|---|---|
|
|
|
|
PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
5e6r | 1 | P20701 | 99.6 | 0.0 |
X-RAY |
2016-03-02 | ALA | A:226 | A:226 | 11.0 | 0.096 | -86.8 | 120.2 | 11.0 | 0.096 | 0.0 |
HOH |
3.333 |
CA |
O |
|||
5e6s | 1 | P20701 | 99.6 | 0.0 |
X-RAY |
2016-03-02 | ALA | A:226 | A:226 | 13.0 | 0.113 | -85.0 | 141.8 | 13.0 | 0.113 | 0.0 |
HOH |
3.320 |
CB |
O |
|||
ALA | C:226 | C:226 | 10.0 | 0.087 | -71.7 | 143.2 | NA | NA | NA | ||||||||||||||
ALA | E:226 | E:226 | 10.0 | 0.087 | -69.4 | 148.1 | NA | NA | NA | ||||||||||||||
5e6u | 1 | P20701 | 99.6 | 0.0 |
X-RAY |
2016-04-06 | ALA | A:226 | A:226 | 9.0 | 0.078 | -83.0 | 133.1 | 9.0 | 0.078 | 0.0 |
HOH |
3.471 |
CB |
O |
|||
7kc3 | 1 | P20701 | 98.98 | 1e-132 |
X-RAY |
2021-10-06 | ALA | A:106 | C:226 | 12.0 | 0.104 | -67.1 | 141.4 | 12.0 | 0.104 | 0.0 |
HOH |
2.735 |
HB1 |
O |
|||
1rd4 | 1 | P20701 | 98.43 | 4e-128 |
X-RAY |
2004-03-30 | ALA | A:106 | A:226 | 12.0 | 0.104 | -73.0 | 140.1 | 12.0 | 0.104 | 0.0 | |||||||
ALA | B:106 | B:226 | 12.0 | 0.104 | -73.4 | 140.6 | NA | NA | NA | ||||||||||||||
ALA | C:106 | C:226 | 12.0 | 0.104 | -70.7 | 140.8 | NA | NA | NA | ||||||||||||||
ALA | D:106 | D:226 | 8.0 | 0.07 | -71.6 | 139.8 | NA | NA | NA | ||||||||||||||
1lfa | 1 | P20701 | 100.0 | 7e-128 |
X-RAY |
1996-01-29 | ALA | A:102 | A:226 | 12.0 | 0.104 | -68.9 | 138.4 | 12.0 | 0.104 | 0.0 |
HOH |
1.865 |
O |
H2 |
|||
ALA | B:102 | B:226 | 12.0 | 0.104 | -74.3 | 135.3 | 12.0 | 0.104 | 0.0 |
HOH |
2.455 |
O |
H1 |
||||||||||
1zon | 1 | P20701 | 100.0 | 7e-128 |
X-RAY |
1996-12-07 | ALA | A:102 | A:226 | 11.0 | 0.096 | -71.7 | 137.6 | 11.0 | 0.096 | 0.0 |
HOH |
3.824 |
CB |
H1 |
|||
1zoo | 1 | P20701 | 100.0 | 7e-128 |
X-RAY |
1996-12-07 | ALA | A:102 | A:226 | 10.0 | 0.087 | -68.1 | 134.2 | 10.0 | 0.087 | 0.0 | |||||||
ALA | B:102 | B:226 | 9.0 | 0.078 | -64.3 | 138.0 | 9.0 | 0.078 | 0.0 | ||||||||||||||
1zop | 1 | P20701 | 100.0 | 7e-128 |
X-RAY |
1996-12-07 | ALA | A:102 | A:226 | 10.0 | 0.087 | -68.1 | 134.2 | 10.0 | 0.087 | 0.0 |
HOH |
1.940 |
O |
H1 |
|||
ALA | B:102 | B:226 | 9.0 | 0.078 | -64.3 | 138.0 | 9.0 | 0.078 | 0.0 |
HOH |
2.255 |
O |
H1 |
||||||||||
1dgq | 1 | P20701 | 99.46 | 1e-124 |
NMR |
2000-02-03 | ALA | A:103 | A:226 | 2.0 | 0.017 | -79.6 | 98.8 | 2.0 | 0.017 | 0.0 | |||||||
1xdd | 1 | P20701 | 99.46 | 1e-124 |
X-RAY |
2004-09-21 | ALA | A:103 | A:226 | 12.0 | 0.104 | -67.1 | 140.2 | 12.0 | 0.104 | 0.0 |
HOH |
2.774 |
O |
O |
|||
ALA | B:103 | B:226 | 13.0 | 0.113 | -60.1 | 143.9 | NA | NA | NA | ||||||||||||||
1xdg | 1 | P20701 | 99.46 | 1e-124 |
X-RAY |
2004-09-21 | ALA | A:103 | A:226 | 12.0 | 0.104 | -65.5 | 139.9 | 12.0 | 0.104 | 0.0 |
HOH |
2.774 |
O |
O |
|||
ALA | B:103 | B:226 | 13.0 | 0.113 | -63.1 | 144.6 | NA | NA | NA | ||||||||||||||
1xuo | 1 | P20701 | 99.46 | 1e-124 |
X-RAY |
2005-10-26 | ALA | A:103 | A:226 | 13.0 | 0.113 | -66.8 | 140.4 | 13.0 | 0.113 | 0.0 |
HOH |
2.857 |
O |
O |
|||
ALA | B:103 | B:226 | 14.0 | 0.122 | -65.8 | 148.0 | NA | NA | NA | ||||||||||||||
4ixd | 1 | P20701 | 99.46 | 1e-124 |
X-RAY |
2014-01-29 | ALA | A:103 | A:226 | 12.0 | 0.104 | -64.4 | 141.7 | 12.0 | 0.104 | 0.0 |
HOH |
2.756 |
O |
O |
|||
7kc5 | 1 | P20701 | 100.0 | 3e-123 |
X-RAY |
2021-10-06 | ALA | A:101 | A:226 | 11.0 | 0.096 | -66.3 | 151.4 | 11.0 | 0.096 | 0.0 |
HOH |
2.767 |
HB1 |
O |
|||
ALA | B:101 | C:226 | 8.0 | 0.07 | -66.2 | 150.8 | NA | NA | NA | ||||||||||||||
7kc6 | 1 | P20701 | 100.0 | 3e-123 |
X-RAY |
2021-10-06 | ALA | A:101 | C:226 | 12.0 | 0.104 | -64.3 | 139.0 | 12.0 | 0.104 | 0.0 |
HOH |
2.551 |
HB1 |
O |
|||
ALA | B:101 | A:226 | 12.0 | 0.104 | -61.3 | 142.0 | NA | NA | NA | ||||||||||||||
3e2m | 1 | P20701 | 99.45 | 6e-123 |
X-RAY |
2008-08-19 | ALA | A:102 | A:226 | 11.0 | 0.096 | -72.1 | 137.9 | 11.0 | 0.096 | 0.0 |
HOH |
2.719 |
O |
O |
|||
ALA | B:102 | B:226 | 13.0 | 0.113 | -69.7 | 148.3 | 13.0 | 0.113 | 0.0 |
HOH |
3.671 |
CB |
O |
||||||||||
3eoa | 3 | P20701 | 100.0 | 8e-123 |
X-RAY |
2009-04-14 | ALA | E:99 | I:226 | 13.0 | 0.113 | -83.6 | 141.8 | 13.0 | 0.113 | 0.0 |
HOH |
4.024 |
CB |
O |
|||
ALA | F:99 | J:226 | 11.0 | 0.096 | -67.2 | 138.5 | NA | NA | NA | ||||||||||||||
3eob | 3 | P20701 | 100.0 | 8e-123 |
X-RAY |
2009-04-14 | ALA | C:99 | I:226 | 16.0 | 0.139 | -97.8 | 146.4 | 16.0 | 0.139 | 0.0 | |||||||
ALA | F:99 | J:226 | 14.0 | 0.122 | -91.7 | 123.3 | NA | NA | NA | ||||||||||||||
1cqp | 1 | P20701 | 99.45 | 2e-122 |
X-RAY |
2000-08-07 | ALA | A:99 | A:226 | 11.0 | 0.096 | -74.9 | 130.6 | 11.0 | 0.096 | 0.0 |
HOH |
3.555 |
CB |
O |
|||
ALA | B:99 | B:226 | 11.0 | 0.096 | -67.8 | 137.7 | NA | NA | NA | ||||||||||||||
3bqm | 1 | P20701 | 99.45 | 2e-122 |
X-RAY |
2008-08-19 | ALA | A:99 | B:226 | 12.0 | 0.104 | -64.5 | 140.2 | 12.0 | 0.104 | 0.0 |
HOH |
2.692 |
O |
O |
|||
ALA | B:99 | C:226 | 13.0 | 0.113 | -70.9 | 144.4 | NA | NA | NA | ||||||||||||||
3bqn | 1 | P20701 | 99.45 | 2e-122 |
X-RAY |
2008-08-19 | ALA | A:99 | B:226 | 13.0 | 0.113 | -62.6 | 139.2 | 13.0 | 0.113 | 0.0 |
HOH |
2.706 |
CB |
O |
|||
ALA | B:99 | C:226 | 15.0 | 0.13 | -66.2 | 144.2 | NA | NA | NA | ||||||||||||||
2ica | 1 | P20701 | 100.0 | 3e-121 |
X-RAY |
2006-12-19 | ALA | A:102 | A:226 | 13.0 | 0.113 | -64.1 | 145.4 | 13.0 | 0.113 | 0.0 |
HOH |
3.381 |
CB |
O |
|||
2o7n | 1 | P20701 | 100.0 | 3e-121 |
X-RAY |
2007-03-20 | ALA | A:102 | A:226 | 11.0 | 0.096 | -64.7 | 144.2 | 11.0 | 0.096 | 0.0 |
HOH |
2.634 |
O |
O |
|||
3m6f | 1 | P20701 | 100.0 | 3e-121 |
X-RAY |
2010-05-12 | ALA | A:102 | A:226 | 13.0 | 0.113 | -63.6 | 148.8 | 13.0 | 0.113 | 0.0 |
HOH |
3.742 |
CB |
O |
|||
3f74 | 1 | P20701 | 99.44 | 5e-121 |
X-RAY |
2009-06-23 | ALA | A:100 | A:226 | 11.0 | 0.096 | -65.0 | 142.8 | 11.0 | 0.096 | 0.0 |
HOH |
2.575 |
O |
O |
|||
ALA | B:100 | B:226 | 12.0 | 0.104 | -63.2 | 143.5 | NA | NA | NA | ||||||||||||||
ALA | C:100 | C:226 | 11.0 | 0.096 | -68.1 | 147.6 | NA | NA | NA | ||||||||||||||
3f78 | 1 | P20701 | 99.44 | 5e-121 |
X-RAY |
2009-06-23 | ALA | A:100 | A:226 | 10.0 | 0.087 | -63.9 | 141.5 | 10.0 | 0.087 | 0.0 |
HOH |
2.730 |
O |
O |
|||
ALA | B:100 | B:226 | 11.0 | 0.096 | -65.6 | 146.3 | NA | NA | NA | ||||||||||||||
ALA | C:100 | C:226 | 12.0 | 0.104 | -62.8 | 145.6 | NA | NA | NA | ||||||||||||||
3hi6 | 1 | P20701 | 98.33 | 3e-119 |
X-RAY |
2009-09-22 | ALA | A:99 | A:226 | 7.0 | 0.061 | -55.9 | 137.7 | NA | NA | NA | |||||||
ALA | B:99 | B:226 | 13.0 | 0.113 | -69.8 | 150.8 | 13.0 | 0.113 | 0.0 |
HOH |
2.805 |
O |
O |
||||||||||
1mjn | 1 | P20701 | 98.88 | 3e-119 |
X-RAY |
2003-01-28 | ALA | A:99 | A:226 | 12.0 | 0.104 | -66.7 | 148.3 | 12.0 | 0.104 | 0.0 |
HOH |
2.628 |
O |
O |
|||
1mq9 | 1 | P20701 | 98.88 | 6e-119 |
X-RAY |
2003-01-14 | ALA | A:100 | A:226 | 10.0 | 0.087 | -68.1 | 137.1 | 10.0 | 0.087 | 0.0 |
HOH |
3.647 |
CA |
O |
|||
1mqa | 1 | P20701 | 98.88 | 6e-119 |
X-RAY |
2003-01-14 | ALA | A:100 | A:226 | 11.0 | 0.096 | -65.1 | 160.7 | 11.0 | 0.096 | 0.0 |
HOH |
3.501 |
CB |
O |
|||
3tcx | 2 | P20701 | 98.88 | 7e-119 |
X-RAY |
2011-08-31 | ALA | B:99 | B:226 | 10.0 | 0.087 | -70.2 | 134.2 | 10.0 | 0.087 | 0.0 | |||||||
ALA | D:99 | D:226 | 9.0 | 0.078 | -70.8 | 136.7 | NA | NA | NA | ||||||||||||||
ALA | F:99 | F:226 | 9.0 | 0.078 | -72.0 | 135.7 | NA | NA | NA | ||||||||||||||
ALA | H:99 | H:226 | 9.0 | 0.078 | -70.9 | 136.0 | NA | NA | NA | ||||||||||||||
ALA | J:99 | J:226 | 9.0 | 0.078 | -72.4 | 135.4 | NA | NA | NA | ||||||||||||||
ALA | L:99 | L:226 | 10.0 | 0.087 | -72.4 | 135.5 | NA | NA | NA | ||||||||||||||
ALA | N:99 | N:226 | 9.0 | 0.078 | -71.8 | 135.4 | NA | NA | NA | ||||||||||||||
ALA | P:99 | P:226 | 10.0 | 0.087 | -70.4 | 134.9 | NA | NA | NA | ||||||||||||||
ALA | R:99 | R:226 | 10.0 | 0.087 | -72.3 | 135.6 | NA | NA | NA | ||||||||||||||
ALA | T:99 | T:226 | 9.0 | 0.078 | -73.1 | 136.1 | NA | NA | NA | ||||||||||||||
ALA | V:99 | V:226 | 9.0 | 0.078 | -71.4 | 137.2 | NA | NA | NA | ||||||||||||||
ALA | X:99 | X:226 | 10.0 | 0.087 | -71.2 | 137.1 | NA | NA | NA | ||||||||||||||
ALA | Z:99 | Z:226 | 10.0 | 0.087 | -74.1 | 135.7 | NA | NA | NA | ||||||||||||||
ALA | BA:99 | b:226 | 9.0 | 0.078 | -72.9 | 135.6 | NA | NA | NA | ||||||||||||||
1mq8 | 2 | P20701 | 98.87 | 2e-117 |
X-RAY |
2003-01-14 | ALA | B:97 | B:226 | 14.0 | 0.122 | -110.3 | 144.8 | 14.0 | 0.122 | 0.0 | |||||||
ALA | D:97 | D:226 | 13.0 | 0.113 | -110.5 | 144.8 | NA | NA | NA | ||||||||||||||
3bn3 | 1 | P20701 | 98.32 | 2e-117 |
X-RAY |
2008-08-19 | ALA | A:99 | A:226 | 12.0 | 0.104 | -62.2 | 142.2 | 12.0 | 0.104 | 0.0 |
HOH |
3.744 |
CB |
O |
|||
6bxb | 1 | P05106,P20701 | 99.44 | 4e-113 |
X-RAY |
2018-08-01 | ALA | A:208 | A:208 | 13.0 | 0.113 | -69.0 | 144.3 | 13.0 | 0.113 | 0.0 |
GOL HOH |
3.248 7.372 |
CB CB |
O1 O |
|||
ALA | B:208 | B:208 | 11.0 | 0.096 | -93.2 | 149.9 | NA | NA | NA | ||||||||||||||
6ckb | 1 | P05106,P20701 | 99.44 | 4e-113 |
X-RAY |
2018-08-01 | ALA | A:208 | A:208 | 11.0 | 0.096 | -69.1 | 139.5 | 11.0 | 0.096 | 0.0 | |||||||
ALA | B:208 | B:208 | 22.0 | 0.191 | -69.7 | 140.9 | NA | NA | NA | ||||||||||||||
6bxf | 1 | P05106,P20701 | 99.44 | 5e-113 |
X-RAY |
2018-08-01 | ALA | A:208 | A:208 | 11.0 | 0.096 | -74.0 | 150.8 | 11.0 | 0.096 | 0.0 | |||||||
ALA | B:208 | B:208 | 10.0 | 0.087 | -69.5 | 127.2 | NA | NA | NA | ||||||||||||||
6bxj | 1 | P05106,P20701 | 99.44 | 8e-112 |
X-RAY |
2018-10-03 | ALA | A:208 | A:208 | 13.0 | 0.113 | -67.2 | 140.9 | 13.0 | 0.113 | 0.0 |
HOH |
3.424 |
CB |
O |
|||
1t0p | 1 | P20701 | 98.28 | 3e-111 |
X-RAY |
2005-03-08 | ALA | A:100 | A:226 | 12.0 | 0.104 | -64.9 | 147.6 | 12.0 | 0.104 | 0.0 |
HOH |
3.514 |
CB |
O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p20701-f1 | 1 | P20701 | 100.0 | 0.0 | ALA | A:251 | A:251 | 7.0 | 0.061 | -66.4 | 139.2 |