Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 30495497 . G A CCDS32433.1:NM_002209.2:c.919Gcg>Acg_NP_002200.2:p.307A>T Homo sapiens integrin subunit alpha L (ITGAL), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5e6r 1 P20701 99.6 0.0 X-RAY
 2016-03-02 ALA A:282 A:282 12.0 0.104 H -59.8 -32.2 12.0 0.104 0.0 HOH
 6.773
 O
 O
5e6s 1 P20701 99.6 0.0 X-RAY
 2016-03-02 ALA A:282 A:282 11.0 0.096 H -58.2 -31.0 11.0 0.096 0.0 HOH
 2.476
 N
 O
ALA C:282 C:282 14.0 0.122 H -67.6 -26.8 NA NA NA
ALA E:282 E:282 13.0 0.113 H -62.4 -24.8 NA NA NA
5e6u 1 P20701 99.6 0.0 X-RAY
 2016-04-06 ALA A:282 A:282 13.0 0.113 H -57.4 -25.6 13.0 0.113 0.0 HOH
 2.868
 N
 O
7kc3 1 P20701 98.98 1e-132 X-RAY
 2021-10-06 ALA A:162 C:282 27.0 0.235 H -56.5 -29.6 27.0 0.235 0.0 HOH
 2.059
 H
 O
1rd4 1 P20701 98.43 4e-128 X-RAY
 2004-03-30 ALA A:162 A:282 25.0 0.217 H -64.4 -32.6 25.0 0.217 0.0 L08
 5.664
 O
 C4
ALA B:162 B:282 29.0 0.252 H -64.6 -32.7 NA NA NA
ALA C:162 C:282 29.0 0.252 H -62.5 -32.6 NA NA NA
ALA D:162 D:282 29.0 0.252 H -64.4 -31.2 NA NA NA
1lfa 1 P20701 100.0 7e-128 X-RAY
 1996-01-29 ALA A:158 A:282 27.0 0.235 H -60.3 -34.5 27.0 0.235 0.0 HOH
 3.300
 O
 H1
ALA B:158 B:282 27.0 0.235 H -64.7 -28.3 27.0 0.235 0.0 HOH
 1.967
 H
 O
1zon 1 P20701 100.0 7e-128 X-RAY
 1996-12-07 ALA A:158 A:282 13.0 0.113 H -66.4 -29.9 13.0 0.113 0.0 HOH
 1.952
 H
 O
1zoo 1 P20701 100.0 7e-128 X-RAY
 1996-12-07 ALA A:158 A:282 26.0 0.226 H -71.8 -25.6 26.0 0.226 0.0
ALA B:158 B:282 28.0 0.243 H -56.8 -35.0 28.0 0.243 0.0
1zop 1 P20701 100.0 7e-128 X-RAY
 1996-12-07 ALA A:158 A:282 26.0 0.226 H -71.8 -25.6 26.0 0.226 0.0 HOH
 3.219
 CA
 H2
ALA B:158 B:282 27.0 0.235 H -56.9 -34.9 27.0 0.235 0.0 HOH
 1.817
 H
 O
1dgq 1 P20701 99.46 1e-124 NMR
 2000-02-03 ALA A:159 A:282 14.0 0.122 H -57.6 -27.0 14.0 0.122 0.0
1xdd 1 P20701 99.46 1e-124 X-RAY
 2004-09-21 ALA A:159 A:282 25.0 0.217 H -56.4 -23.5 25.0 0.217 0.0 AAY
HOH
 9.764
3.467
 O
N
 O52
O
ALA B:159 B:282 27.0 0.235 H -49.5 -33.8 NA NA NA
1xdg 1 P20701 99.46 1e-124 X-RAY
 2004-09-21 ALA A:159 A:282 24.0 0.209 H -54.1 -34.9 24.0 0.209 0.0 AB8
HOH
 9.756
3.310
 N
CB
 C81
O
ALA B:159 B:282 19.0 0.165 H -57.4 -15.5 NA NA NA
1xuo 1 P20701 99.46 1e-124 X-RAY
 2005-10-26 ALA A:159 A:282 21.0 0.183 H -57.3 -29.4 21.0 0.183 0.0 LA1
HOH
 9.466
3.043
 O
N
 C6
O
ALA B:159 B:282 17.0 0.148 H -60.3 -31.3 NA NA NA
4ixd 1 P20701 99.46 1e-124 X-RAY
 2014-01-29 ALA A:159 A:282 24.0 0.209 H -59.3 -31.0 24.0 0.209 0.0 1HV
HOH
 9.981
2.918
 O
N
 C11
O
7kc5 1 P20701 100.0 3e-123 X-RAY
 2021-10-06 ALA A:157 A:282 27.0 0.235 H -58.2 -25.7 27.0 0.235 0.0 BJZ
HOH
 9.670
2.377
 O
H
 CL56
O
ALA B:157 C:282 26.0 0.226 H -58.9 -28.8 NA NA NA
7kc6 1 P20701 100.0 3e-123 X-RAY
 2021-10-06 ALA A:157 C:282 17.0 0.148 H -59.5 -23.4 17.0 0.148 0.0 803
HOH
 9.700
4.086
 O
O
 O5
O
ALA B:157 A:282 17.0 0.148 H -60.9 -30.2 NA NA NA
3e2m 1 P20701 99.45 6e-123 X-RAY
 2008-08-19 ALA A:158 A:282 28.0 0.243 H -60.7 -29.7 28.0 0.243 0.0 E2M
HOH
 6.066
3.212
 O
O
 C15
O
ALA B:158 B:282 26.0 0.226 H -53.9 -34.0 26.0 0.226 0.0 E2M
HOH
 5.995
3.046
 O
N
 C15
O
3eoa 3 P20701 100.0 8e-123 X-RAY
 2009-04-14 ALA E:155 I:282 20.0 0.174 H -56.3 -36.4 20.0 0.174 0.0 HOH
 3.199
 N
 O
ALA F:155 J:282 17.0 0.148 G -52.1 -37.3 NA NA NA
3eob 3 P20701 100.0 8e-123 X-RAY
 2009-04-14 ALA C:155 I:282 22.0 0.191 H -66.2 -22.9 22.0 0.191 0.0
ALA F:155 J:282 26.0 0.226 H -39.0 -31.7 NA NA NA
1cqp 1 P20701 99.45 2e-122 X-RAY
 2000-08-07 ALA A:155 A:282 23.0 0.2 H -56.3 -36.1 23.0 0.2 0.0 HOH
 3.866
 O
 O
ALA B:155 B:282 28.0 0.243 T -75.2 36.2 NA NA NA
3bqm 1 P20701 99.45 2e-122 X-RAY
 2008-08-19 ALA A:155 B:282 26.0 0.226 H -57.1 -37.0 26.0 0.226 0.0 BQM
HOH
 5.788
3.595
 O
CA
 C17
O
ALA B:155 C:282 26.0 0.226 H -55.1 -30.8 NA NA NA
3bqn 1 P20701 99.45 2e-122 X-RAY
 2008-08-19 ALA A:155 B:282 24.0 0.209 H -57.0 -33.8 24.0 0.209 0.0 BQN
HOH
 6.224
3.432
 O
O
 C17
O
ALA B:155 C:282 25.0 0.217 H -56.6 -30.5 NA NA NA
2ica 1 P20701 100.0 3e-121 X-RAY
 2006-12-19 ALA A:158 A:282 15.0 0.13 H -58.2 -29.4 15.0 0.13 0.0 2IC
HOH
 9.430
2.820
 O
N
 CL57
O
2o7n 1 P20701 100.0 3e-121 X-RAY
 2007-03-20 ALA A:158 A:282 21.0 0.183 H -59.0 -29.0 21.0 0.183 0.0 2O7
HOH
 9.713
3.006
 O
N
 CL27
O
3m6f 1 P20701 100.0 3e-121 X-RAY
 2010-05-12 ALA A:158 A:282 16.0 0.139 H -55.3 -32.8 16.0 0.139 0.0 BJZ
NO3
HOH
 9.338
7.368
2.861
 O
CB
N
 CL10
O3
O
3f74 1 P20701 99.44 5e-121 X-RAY
 2009-06-23 ALA A:156 A:282 24.0 0.209 H -52.4 -31.7 24.0 0.209 0.0 HOH
 3.645
 O
 O
ALA B:156 B:282 24.0 0.209 H -54.3 -32.0 NA NA NA
ALA C:156 C:282 25.0 0.217 H -59.0 -31.8 NA NA NA
3f78 1 P20701 99.44 5e-121 X-RAY
 2009-06-23 ALA A:156 A:282 24.0 0.209 H -51.2 -34.8 24.0 0.209 0.0 ICF
GOL
HOH
 9.028
3.127
3.657
 O
O
CA
 FAE
O3
O
ALA B:156 B:282 24.0 0.209 H -53.9 -32.8 NA NA NA
ALA C:156 C:282 26.0 0.226 H -59.2 -32.4 NA NA NA
3hi6 1 P20701 98.33 3e-119 X-RAY
 2009-09-22 ALA A:155 A:282 10.0 0.087 G -60.1 -31.1 NA NA NA
ALA B:155 B:282 17.0 0.148 G -53.9 -33.1 17.0 0.148 0.0 HOH
 4.741
 O
 O
1mjn 1 P20701 98.88 3e-119 X-RAY
 2003-01-28 ALA A:155 A:282 15.0 0.13 H -57.9 -30.3 15.0 0.13 0.0 HOH
 2.829
 N
 O
1mq9 1 P20701 98.88 6e-119 X-RAY
 2003-01-14 ALA A:156 A:282 13.0 0.113 H -48.6 -41.5 13.0 0.113 0.0 HOH
 4.813
 O
 O
1mqa 1 P20701 98.88 6e-119 X-RAY
 2003-01-14 ALA A:156 A:282 24.0 0.209 H -58.5 -33.6 24.0 0.209 0.0 HOH
 3.335
 CB
 O
3tcx 2 P20701 98.88 7e-119 X-RAY
 2011-08-31 ALA B:155 B:282 24.0 0.209 S -47.7 -51.3 24.0 0.209 0.0
ALA D:155 D:282 24.0 0.209 S -47.9 -50.1 NA NA NA
ALA F:155 F:282 25.0 0.217 S -47.1 -52.3 NA NA NA
ALA H:155 H:282 24.0 0.209 S -46.4 -51.0 NA NA NA
ALA J:155 J:282 25.0 0.217 S -46.0 -51.7 NA NA NA
ALA L:155 L:282 24.0 0.209 S -48.2 -48.9 NA NA NA
ALA N:155 N:282 24.0 0.209 S -46.7 -50.4 NA NA NA
ALA P:155 P:282 24.0 0.209 S -46.7 -50.8 NA NA NA
ALA R:155 R:282 26.0 0.226 S -47.4 -50.3 NA NA NA
ALA T:155 T:282 25.0 0.217 S -47.4 -49.9 NA NA NA
ALA V:155 V:282 24.0 0.209 S -46.2 -50.9 NA NA NA
ALA X:155 X:282 24.0 0.209 S -45.6 -53.3 NA NA NA
ALA Z:155 Z:282 25.0 0.217 S -46.2 -51.8 NA NA NA
ALA BA:155 b:282 24.0 0.209 S -46.6 -50.6 NA NA NA
1mq8 2 P20701 98.87 2e-117 X-RAY
 2003-01-14 ALA B:153 B:282 114.0 0.991 S -51.6 92.4 114.0 0.991 0.0
ALA D:153 D:282 111.0 0.965 S -49.9 95.1 NA NA NA
3bn3 1 P20701 98.32 2e-117 X-RAY
 2008-08-19 ALA A:155 A:282 10.0 0.087 H -55.9 -30.4 10.0 0.087 0.0 HOH
 3.503
 N
 O
6bxb 1 P05106,P20701 99.44 4e-113 X-RAY
 2018-08-01 ALA A:264 A:264 21.0 0.183 H -61.3 -28.2 21.0 0.183 0.0 HOH
 3.476
 CA
 O
ALA B:264 B:264 23.0 0.2 T -71.4 8.5 NA NA NA
6ckb 1 P05106,P20701 99.44 4e-113 X-RAY
 2018-08-01 ALA A:264 A:264 18.0 0.157 H -77.6 -16.9 18.0 0.157 0.0
ALA B:264 B:264 33.0 0.287 T -89.2 19.0 NA NA NA
6bxf 1 P05106,P20701 99.44 5e-113 X-RAY
 2018-08-01 ALA A:264 A:264 19.0 0.165 H -65.0 -15.9 19.0 0.165 0.0 GOL
HOH
 5.368
9.764
 O
N
 O2
O
ALA B:264 B:264 20.0 0.174 T -68.7 -13.1 NA NA NA
6bxj 1 P05106,P20701 99.44 8e-112 X-RAY
 2018-10-03 ALA A:264 A:264 27.0 0.235 H -60.5 -33.1 27.0 0.235 0.0 HOH
 2.738
 N
 O
1t0p 1 P20701 98.28 3e-111 X-RAY
 2005-03-08 ALA A:156 A:282 34.0 0.296 H -59.4 -30.3 34.0 0.296 0.0 HOH
 2.888
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p20701-f1 1 P20701 100.0 0.0 ALA A:307 A:307 13.0 0.113 H -65.7 -32.5