Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 31004504 . G A CCDS10699.1:NM_052874.3:c.733Cga>Tga_NP_443106.1:p.245R>* Homo sapiens syntaxin 1B (STX1B), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3c98 2 P32851 83.15 8e-149 X-RAY
 2008-03-25 ARG B:258 B:246 144.0 0.64 -84.3 131.2 144.0 0.64 0.0 HOH
 4.485
 CA
 O
4jeh 2 P32851 85.6 6e-145 X-RAY
 2013-07-17 ARG B:223 B:246 168.0 0.747 -80.4 130.0 168.0 0.747 0.0 HOH
 3.991
 NH1
 O
6mdm 3 P32851 82.03 3e-139 EM
 2018-09-19 ARG H:246 I:246 148.0 0.658 H -71.2 -31.1 7.0 0.031 0.627 J:P54921:0.609
I:P63045:0.116
6mdn 3 P32851 82.03 3e-139 EM
 2018-09-19 ARG H:246 I:246 161.0 0.716 H -64.7 -22.6 5.0 0.022 0.694 J:P54921:0.684
I:P63045:0.053
6ip1 2 P32851 82.14 3e-137 EM
 2019-04-24 ARG B:247 B:246 162.0 0.72 H -68.1 -25.2 74.0 0.329 0.391 A:P63045:0.258
F:A5D7S0:0.129
2m8r 1 P32851 85.85 2e-63 NMR
 2013-11-20 ARG A:67 A:246 160.0 0.711 H -81.7 -23.0 160.0 0.711 0.0
3hd7 2 P32851 85.85 2e-63 X-RAY
 2009-07-14 ARG B:67 B:246 141.0 0.627 H -65.5 -55.1 107.0 0.476 0.151 A:P63045:0.151
 GGG
 8.442
 O
 O1
ARG F:67 F:246 141.0 0.627 H -67.6 -59.6 NA NA NA
3ipd 2 P32851 85.85 2e-63 X-RAY
 2009-09-01 ARG B:67 B:246 148.0 0.658 H -77.6 -47.4 124.0 0.551 0.107 A:P63045:0.107
ARG F:67 F:246 147.0 0.653 H -78.0 -46.8 NA NA NA
1sfc 2 P32851 89.02 6e-46 X-RAY
 1998-10-28 ARG B:67 B:246 128.0 0.569 H -55.8 -52.6 93.0 0.413 0.156 A:P63045:0.156
 SR
HOH
 6.662
2.571
 NH1
NH2
 SR
O
ARG F:67 F:246 128.0 0.569 H -60.5 -43.5 NA NA NA
ARG J:67 J:246 132.0 0.587 H -61.2 -36.8 NA NA NA
1jth 2 P32851 93.51 3e-45 X-RAY
 2001-11-28 ARG B:56 B:246 178.0 0.791 H -75.9 -41.0 178.0 0.791 0.0 HOH
 7.578
 N
 O
ARG D:56 NA:NA DO NA DO DO DO NA NA NA
1hvv 1 P32851 93.33 7e-44 X-RAY
 2001-01-31 ARG A:57 A:246 128.0 0.569 H -53.9 -45.9 124.0 0.551 0.018 B:P32851:0.018
 HOH
 2.651
 NH1
 O
ARG B:57 B:246 163.0 0.724 H -65.2 -49.3 163.0 0.724 0.0 HOH
 4.467
 CZ
 O
ARG C:57 C:246 171.0 0.76 H -72.0 -45.1 171.0 0.76 0.0
ARG D:57 D:246 172.0 0.764 H -63.3 -48.9 172.0 0.764 0.0 HOH
 4.018
 CD
 O
2n1t 2 P32851 91.67 4e-41 NMR
 2015-06-03 ARG B:59 B:246 111.0 0.493 H -64.7 -48.1 78.0 0.347 0.146 A:P63045:0.147
1urq 2 P32851 91.67 5e-41 X-RAY
 2004-08-26 ARG B:62 B:246 133.0 0.591 H -62.8 -38.5 119.0 0.529 0.062 A:Q9Z152:0.062
 HOH
 3.333
 O
 O
5kj7 2 P32851 92.42 1e-36 X-RAY
 2016-10-19 ARG B:56 B:246 160.0 0.711 H -63.2 -49.4 130.0 0.578 0.133 A:P63025:0.133
 HOH
 5.007
 NH2
 O
ARG H:56 H:246 151.0 0.671 H -62.2 -47.9 NA NA NA
5kj8 2 P32851 92.42 1e-36 X-RAY
 2016-10-19 ARG B:56 B:246 153.0 0.68 H -57.2 -49.2 126.0 0.56 0.12 A:P63025:0.12
ARG H:56 H:246 151.0 0.671 H -56.6 -48.7 NA NA NA
6wvw 2 P32851 92.42 1e-36 X-RAY
 2021-03-17 ARG B:56 B:246 188.0 0.836 H -65.8 -39.6 166.0 0.738 0.098 A:P63045:0.098
 HOH
 1.688
 HH21
 O
ARG F:56 F:246 147.0 0.653 H -63.3 -42.2 NA NA NA
3j96 4 P32851 92.42 1e-36 EM
 2015-01-28 ARG L:57 L:246 151.0 0.671 H -75.0 -22.7 79.0 0.351 0.32 J:P54921:0.213
K:P63045:0.116
3j97 4 P32851 92.42 1e-36 EM
 2015-01-28 ARG L:57 L:246 160.0 0.711 H -82.6 -29.0 88.0 0.391 0.32 J:P54921:0.276
K:P63045:0.04
3j98 4 P32851 92.42 1e-36 EM
 2015-01-28 ARG L:57 L:246 152.0 0.676 H -72.5 -28.1 85.0 0.378 0.298 J:P54921:0.236
K:P63045:0.076
3j99 4 P32851 92.42 1e-36 EM
 2015-01-28 ARG L:57 L:246 152.0 0.676 H -72.4 -28.1 79.0 0.351 0.325 J:P54921:0.271
K:P63045:0.071
5ccg 2 P32851 92.42 1e-36 X-RAY
 2015-08-12 ARG B:57 B:246 160.0 0.711 H -59.9 -50.6 130.0 0.578 0.133 A:P63045:0.133
 HOH
 5.219
 NH2
 O
ARG H:57 H:246 152.0 0.676 H -59.0 -49.2 NA NA NA
5cch 2 P32851 92.42 1e-36 X-RAY
 2015-08-12 ARG B:57 B:246 168.0 0.747 H -60.5 -42.5 141.0 0.627 0.12 A:P63045:0.12
5cci 2 P32851 92.42 1e-36 X-RAY
 2015-08-12 ARG B:57 B:246 153.0 0.68 H -61.6 -42.4 117.0 0.52 0.16 A:P63045:0.16
5w5c 2 P32851 92.42 1e-36 X-RAY
 2017-08-23 ARG B:57 NA:NA DO NA DO DO DO NA NA NA
5w5d 2 P32851 92.42 1e-36 X-RAY
 2017-08-23 ARG B:57 NA:NA DO NA DO DO DO NA NA NA
6mti 4 P32851 92.42 1e-36 EM
 2019-04-24 ARG H:57 B:246 153.0 0.68 H -61.6 -42.4 25.0 0.111 0.569 AA:P63045:0.196
BA:P32851:0.329
G:P63045:0.164
ARG L:57 F:246 155.0 0.689 H -61.6 -42.4 118.0 0.524 0.165 K:P63045:0.164
ARG P:57 J:246 152.0 0.676 H -61.5 -42.4 27.0 0.12 0.556 T:P32851:0.293
S:P63045:0.191
O:P63045:0.16
ARG T:57 N:246 154.0 0.684 H -61.7 -42.3 29.0 0.129 0.555 P:P32851:0.302
O:P63045:0.173
S:P63045:0.164
ARG X:57 R:246 154.0 0.684 H -61.6 -42.4 119.0 0.529 0.155 W:P63045:0.156
ARG BA:57 V:246 154.0 0.684 H -61.6 -42.4 24.0 0.107 0.577 AA:P63045:0.16
G:P63045:0.218
H:P32851:0.307
1n7s 2 P32851 92.42 1e-36 X-RAY
 2002-12-27 ARG B:58 B:246 154.0 0.684 H -68.6 -40.0 130.0 0.578 0.106 A:P63045:0.107
 HOH
 2.784
 NH2
 O
3rk2 2 P32851 92.06 1e-34 X-RAY
 2011-07-27 ARG B:58 B:246 197.0 0.876 H -66.7 -34.6 197.0 0.876 0.0 HOH
 6.440
 N
 O
ARG F:58 F:246 191.0 0.849 H -71.8 -37.1 NA NA NA
3rk3 2 P32851 92.06 1e-34 X-RAY
 2011-07-27 ARG B:58 B:246 193.0 0.858 H -69.7 -26.9 193.0 0.858 0.0
3rl0 2 P32851 92.06 1e-34 X-RAY
 2011-07-27 ARG B:58 B:246 193.0 0.858 H -68.0 -37.8 193.0 0.858 0.0
ARG F:58 F:246 175.0 0.778 H -68.0 -37.8 NA NA NA
ARG J:58 J:246 231.0 1.0 H -68.2 -37.9 NA NA NA
ARG N:58 N:246 195.0 0.867 H -67.5 -38.9 NA NA NA
ARG R:58 R:246 180.0 0.8 H -65.9 -39.9 NA NA NA
ARG V:58 V:246 177.0 0.787 H -68.8 -37.6 NA NA NA
ARG Z:58 Z:246 206.0 0.916 H -67.8 -37.5 NA NA NA
ARG DA:58 d:246 169.0 0.751 H -67.9 -38.9 NA NA NA
1kil 2 P32851 91.67 3e-32 X-RAY
 2002-03-13 ARG B:58 B:246 155.0 0.689 H -67.3 -38.8 108.0 0.48 0.209 A:P63045:0.209
 HOH
 3.644
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p61266-f1 1 P61266 100.0 0.0 ARG A:245 A:245 150.0 0.667 H -64.5 -44.2
af-q16623-f1 1 Q16623 81.6 2e-161 ARG A:246 A:246 155.0 0.689 H -64.8 -44.2