Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 31004696 . A C CCDS10699.1:NM_052874.3:c.647gTg>gGg_NP_443106.1:p.216V>G Homo sapiens syntaxin 1B (STX1B), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3c98 2 P32851 83.15 8e-149 X-RAY
 2008-03-25 MET B:229 B:217 87.0 0.47 H -65.3 -43.4 39.0 0.211 0.259 A:P61765:0.259
4jeh 2 P32851 85.6 6e-145 X-RAY
 2013-07-17 MET B:194 B:217 83.0 0.449 H -62.2 -43.2 26.0 0.141 0.308 A:P61765:0.308
 HOH
 6.829
 N
 O
6mdm 3 P32851 82.03 3e-139 EM
 2018-09-19 MET H:217 I:217 75.0 0.405 H -63.3 -32.5 36.0 0.195 0.21 K:P54921:0.092
G:P60881:0.124
6mdn 3 P32851 82.03 3e-139 EM
 2018-09-19 MET H:217 I:217 80.0 0.432 H -70.2 -14.2 38.0 0.205 0.227 K:P54921:0.168
G:P60881:0.13
6ip1 2 P32851 82.14 3e-137 EM
 2019-04-24 MET B:218 B:217 106.0 0.573 H -67.6 -28.5 24.0 0.13 0.443 E:A5D7S0:0.281
C:P60881:0.243
4jeu 2 P32851 81.4 4e-130 X-RAY
 2013-07-17 MET B:216 B:217 101.0 0.546 H -58.0 -45.4 46.0 0.249 0.297 A:P61765:0.297
2m8r 1 P32851 85.85 2e-63 NMR
 2013-11-20 MET A:38 A:217 144.0 0.778 H -78.1 -30.8 144.0 0.778 0.0
3hd7 2 P32851 85.85 2e-63 X-RAY
 2009-07-14 MET B:38 B:217 101.0 0.546 H -71.9 -50.5 47.0 0.254 0.292 C:P60881:0.292
 SO4
 5.777
 CE
 O2
MET F:38 F:217 103.0 0.557 H -65.3 -48.9 NA NA NA
3ipd 2 P32851 85.85 2e-63 X-RAY
 2009-09-01 MET B:38 B:217 105.0 0.568 H -86.7 -26.4 54.0 0.292 0.276 C:P60881:0.276
MET F:38 F:217 106.0 0.573 H -86.4 -26.9 NA NA NA
1sfc 2 P32851 89.02 6e-46 X-RAY
 1998-10-28 MET B:38 B:217 97.0 0.524 H -65.0 -39.8 56.0 0.303 0.221 C:P60881:0.222
 SR
 6.966
 CB
 SR
MET F:38 F:217 87.0 0.47 H -58.5 -38.0 NA NA NA
MET J:38 J:217 102.0 0.551 H -62.9 -37.5 NA NA NA
1jth 2 P32851 93.51 3e-45 X-RAY
 2001-11-28 MET B:27 B:217 101.0 0.546 H -61.6 -47.5 56.0 0.303 0.243 C:P60881:0.243
 HOH
 3.553
 CE
 O
MET D:27 D:217 102.0 0.551 H -66.7 -41.2 39.0 0.211 0.34 A:P60881:0.341
 HOH
 3.830
 CB
 O
1hvv 1 P32851 93.33 7e-44 X-RAY
 2001-01-31 MET A:28 A:217 60.0 0.324 H -64.9 -30.3 42.0 0.227 0.097 C:P32851:0.097
 HOH
 3.379
 CE
 O
MET B:28 B:217 105.0 0.568 H -68.7 -38.8 97.0 0.524 0.044 A:P32851:0.043
 HOH
 5.643
 O
 O
MET C:28 C:217 71.0 0.384 H -66.7 -32.6 71.0 0.384 0.0 TAR
HOH
 4.432
3.203
 SD
CE
 O1
O
MET D:28 D:217 114.0 0.616 H -67.5 -49.7 94.0 0.508 0.108 C:P32851:0.108
 HOH
 4.473
 CB
 O
2n1t 2 P32851 91.67 4e-41 NMR
 2015-06-03 MET B:30 B:217 108.0 0.584 H -64.7 -44.0 64.0 0.346 0.238 E:P21579:0.076
C:P60880:0.168
1urq 2 P32851 91.67 5e-41 X-RAY
 2004-08-26 MET B:33 B:217 107.0 0.578 H -62.5 -42.0 72.0 0.389 0.189 C:P13795:0.189
 HOH
 2.868
 O
 O
5kj7 2 P32851 92.42 1e-36 X-RAY
 2016-10-19 MET B:27 B:217 104.0 0.562 H -65.0 -45.6 76.0 0.411 0.151 C:P60881:0.151
MET H:27 H:217 101.0 0.546 H -64.5 -47.6 NA NA NA
5kj8 2 P32851 92.42 1e-36 X-RAY
 2016-10-19 MET B:27 B:217 111.0 0.6 H -65.1 -43.0 71.0 0.384 0.216 C:P60881:0.216
MET H:27 H:217 109.0 0.589 H -64.7 -44.1 NA NA NA
6wvw 2 P32851 92.42 1e-36 X-RAY
 2021-03-17 MET B:27 B:217 93.0 0.503 H -65.2 -45.2 58.0 0.314 0.189 C:P60881:0.189
 HOH
 5.122
 N
 O
MET F:27 F:217 102.0 0.551 H -64.8 -45.2 NA NA NA
3j96 4 P32851 92.42 1e-36 EM
 2015-01-28 MET L:28 L:217 111.0 0.6 H -71.7 -61.4 30.0 0.162 0.438 M:None:0.005
G:P54921:0.432
3j97 4 P32851 92.42 1e-36 EM
 2015-01-28 MET L:28 L:217 112.0 0.605 H -61.4 -58.7 21.0 0.114 0.491 M:None:0.151
G:P54921:0.465
3j98 4 P32851 92.42 1e-36 EM
 2015-01-28 MET L:28 L:217 118.0 0.638 H -55.9 -50.6 23.0 0.124 0.514 M:None:0.13
G:P54921:0.486
3j99 4 P32851 92.42 1e-36 EM
 2015-01-28 MET L:28 L:217 119.0 0.643 H -55.9 -50.7 13.0 0.07 0.573 M:None:0.119
G:P54921:0.557
5ccg 2 P32851 92.42 1e-36 X-RAY
 2015-08-12 MET B:28 B:217 104.0 0.562 H -63.8 -44.0 40.0 0.216 0.346 C:P60881:0.151
F:P21707:0.189
MET H:28 H:217 97.0 0.524 H -62.8 -45.9 NA NA NA
5cch 2 P32851 92.42 1e-36 X-RAY
 2015-08-12 MET B:28 B:217 108.0 0.584 H -58.8 -48.7 41.0 0.222 0.362 C:P60881:0.238
F:P21707:0.119
5cci 2 P32851 92.42 1e-36 X-RAY
 2015-08-12 MET B:28 B:217 106.0 0.573 H -60.5 -50.8 67.0 0.362 0.211 C:P60881:0.184
F:P21707:0.027
5w5c 2 P32851 92.42 1e-36 X-RAY
 2017-08-23 MET B:28 B:217 108.0 0.584 H -68.9 -41.4 51.0 0.276 0.308 C:P60881:0.308
 HOH
 2.617
 O
 O
5w5d 2 P32851 92.42 1e-36 X-RAY
 2017-08-23 MET B:28 B:217 102.0 0.551 H -63.6 -44.3 50.0 0.27 0.281 C:P60881:0.281
 HOH
 3.049
 O
 O
6mti 4 P32851 92.42 1e-36 EM
 2019-04-24 MET H:28 B:217 106.0 0.573 H -60.4 -50.8 70.0 0.378 0.195 I:P60881:0.195
MET L:28 F:217 104.0 0.562 H -60.4 -50.8 69.0 0.373 0.189 M:P60881:0.189
MET P:28 J:217 107.0 0.578 H -60.4 -50.8 73.0 0.395 0.183 Q:P60881:0.184
MET T:28 N:217 106.0 0.573 H -60.5 -50.8 72.0 0.389 0.184 U:P60881:0.184
MET X:28 R:217 106.0 0.573 H -60.5 -50.8 70.0 0.378 0.195 Y:P60881:0.195
MET BA:28 V:217 106.0 0.573 H -60.4 -50.9 71.0 0.384 0.189 CA:P60881:0.189
1n7s 2 P32851 92.42 1e-36 X-RAY
 2002-12-27 MET B:29 B:217 110.0 0.595 H -64.2 -44.4 55.0 0.297 0.298 C:P60881:0.297
 HOH
 2.848
 O
 O
3rk2 2 P32851 92.06 1e-34 X-RAY
 2011-07-27 MET B:29 B:217 94.0 0.508 H -72.2 -47.4 36.0 0.195 0.313 C:P60880:0.314
 HOH
 4.867
 N
 O
MET F:29 F:217 96.0 0.519 H -84.2 -55.0 NA NA NA
3rk3 2 P32851 92.06 1e-34 X-RAY
 2011-07-27 MET B:29 B:217 106.0 0.573 H -71.3 -61.3 63.0 0.341 0.232 C:P60880:0.232
3rl0 2 P32851 92.06 1e-34 X-RAY
 2011-07-27 MET B:29 B:217 94.0 0.508 H -71.0 -47.7 28.0 0.151 0.357 C:P60880:0.357
MET F:29 F:217 93.0 0.503 H -70.2 -47.0 NA NA NA
MET J:29 J:217 91.0 0.492 H -72.0 -44.0 NA NA NA
MET N:29 N:217 94.0 0.508 H -71.5 -45.7 NA NA NA
MET R:29 R:217 93.0 0.503 H -70.1 -47.2 NA NA NA
MET V:29 V:217 93.0 0.503 H -71.4 -47.3 NA NA NA
MET Z:29 Z:217 93.0 0.503 H -71.0 -45.8 NA NA NA
MET DA:29 d:217 94.0 0.508 H -71.7 -44.2 NA NA NA
1kil 2 P32851 91.67 3e-32 X-RAY
 2002-03-13 MET B:29 B:217 88.0 0.476 H -65.2 -47.8 43.0 0.232 0.244 C:P60880:0.243
 HOH
 4.693
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p61266-f1 1 P61266 100.0 0.0 VAL A:216 A:216 82.0 0.529 H -60.1 -42.8
af-q16623-f1 1 Q16623 81.6 2e-161 MET A:217 A:217 106.0 0.573 H -62.3 -38.5