Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55844431 . C A CCDS32450.1:NM_001025195.1:c.1316aGa>aTa_NP_001020366.1:p.439R>I Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 ARG A:419 A:1438 26.0 0.116 H -61.9 -53.8 26.0 0.116 0.0 HOH
 2.857
 O
 O
ARG B:419 B:2438 33.0 0.147 H -62.4 -53.4 33.0 0.147 0.0 HOH
 2.900
 O
 O
ARG C:419 C:3438 26.0 0.116 H -59.4 -53.2 26.0 0.116 0.0 HOH
 2.882
 NH2
 O
ARG D:419 D:4438 29.0 0.129 H -59.4 -50.8 29.0 0.129 0.0 HOH
 3.188
 O
 O
ARG E:419 E:5438 30.0 0.133 H -58.2 -46.4 30.0 0.133 0.0 HOH
 2.869
 O
 O
ARG F:419 F:6438 27.0 0.12 H -62.8 -51.4 27.0 0.12 0.0 HOH
 2.954
 NH2
 O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 ARG A:419 A:1438 31.0 0.138 H -60.4 -51.0 31.0 0.138 0.0 HOH
 2.716
 NH2
 O
ARG B:419 B:2438 30.0 0.133 H -60.3 -55.1 30.0 0.133 0.0 HOH
 2.617
 O
 O
ARG C:419 C:3438 29.0 0.129 H -57.0 -46.8 29.0 0.129 0.0 HOH
 3.775
 CG
 O
ARG D:419 D:4438 25.0 0.111 H -58.9 -57.1 NA NA NA
ARG E:419 E:5438 32.0 0.142 H -58.3 -54.2 NA NA NA
ARG F:419 F:6438 34.0 0.151 H -60.9 -48.3 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 ARG A:419 A:1438 33.0 0.147 H -54.6 -51.2 33.0 0.147 0.0 HOH
 4.368
 O
 O
ARG B:419 B:2438 30.0 0.133 H -53.9 -58.9 30.0 0.133 0.0 HOH
 3.102
 NH2
 O
ARG C:419 C:3438 29.0 0.129 H -56.3 -57.4 29.0 0.129 0.0 HOH
 2.569
 NH2
 O
ARG D:419 D:4438 30.0 0.133 H -62.9 -49.8 30.0 0.133 0.0 HOH
 4.114
 CG
 O
ARG E:419 E:5438 31.0 0.138 H -55.3 -53.1 31.0 0.138 0.0 HOH
 6.360
 NH1
 O
ARG F:419 F:6438 31.0 0.138 H -52.1 -58.9 31.0 0.138 0.0 HOH
 3.300
 NH1
 O
ARG G:419 G:1438 38.0 0.169 H -60.4 -53.7 NA NA NA
ARG H:419 H:2438 31.0 0.138 H -58.0 -48.7 NA NA NA
ARG I:419 I:3438 35.0 0.156 H -63.3 -41.8 NA NA NA
ARG J:419 J:4438 27.0 0.12 H -58.6 -51.3 NA NA NA
ARG K:419 K:5438 29.0 0.129 H -61.6 -54.6 NA NA NA
ARG L:419 L:6438 36.0 0.16 H -52.2 -65.6 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ARG A:419 A:1438 32.0 0.142 H -67.6 -60.2 32.0 0.142 0.0 HOH
 6.608
 NH1
 O
ARG B:419 B:2438 31.0 0.138 H -68.5 -60.3 31.0 0.138 0.0 HOH
 5.990
 NH2
 O
ARG C:419 C:3438 31.0 0.138 H -68.5 -59.5 31.0 0.138 0.0 HOH
 2.570
 O
 O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ARG A:419 A:1438 30.0 0.133 H -58.6 -53.5 30.0 0.133 0.0 HOH
 3.487
 CG
 O
ARG B:419 B:2438 32.0 0.142 H -64.2 -53.9 32.0 0.142 0.0 HOH
 5.710
 CD
 O
ARG C:419 C:3438 32.0 0.142 H -62.5 -53.7 32.0 0.142 0.0 HOH
 2.630
 O
 O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ARG A:419 A:1438 29.0 0.129 H -59.3 -55.0 29.0 0.129 0.0 HOH
 9.021
 N
 O
ARG B:419 B:2438 28.0 0.124 H -59.4 -55.4 28.0 0.124 0.0 HOH
 7.007
 CD
 O
ARG C:419 C:3438 29.0 0.129 H -59.0 -55.7 29.0 0.129 0.0 HOH
 2.790
 CG
 O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ARG A:419 A:1438 31.0 0.138 H -54.6 -51.1 31.0 0.138 0.0 HOH
 2.834
 O
 O
ARG B:419 B:2438 31.0 0.138 H -59.2 -47.1 31.0 0.138 0.0 HOH
 2.855
 O
 O
ARG C:419 C:3438 26.0 0.116 H -60.0 -48.5 26.0 0.116 0.0 HOH
 2.863
 O
 O
ARG D:419 D:4438 30.0 0.133 H -57.4 -47.2 30.0 0.133 0.0 HOH
 2.888
 O
 O
ARG E:419 E:5438 29.0 0.129 H -55.4 -49.1 29.0 0.129 0.0 HOH
 2.768
 O
 O
ARG F:419 F:6438 28.0 0.124 H -61.8 -50.9 28.0 0.124 0.0 HOH
 2.922
 O
 O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ARG A:417 A:438 32.0 0.142 H -59.9 -46.3 32.0 0.142 0.0 HOH
 3.432
 CG
 O
ARG B:417 B:438 32.0 0.142 H -65.1 -52.1 32.0 0.142 0.0 HOH
 6.434
 NH1
 O
ARG C:417 C:438 31.0 0.138 H -66.2 -47.9 31.0 0.138 0.0 HOH
 6.714
 CD
 O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ARG A:417 A:438 31.0 0.138 H -54.0 -53.5 31.0 0.138 0.0 HOH
 2.841
 O
 O
ARG B:417 B:438 30.0 0.133 H -61.5 -58.3 30.0 0.133 0.0 HOH
 4.495
 O
 O
ARG C:417 C:438 27.0 0.12 H -57.2 -49.7 27.0 0.12 0.0 HOH
 2.528
 O
 O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ARG A:417 A:438 29.0 0.129 H -60.0 -55.0 29.0 0.129 0.0 HOH
 6.452
 N
 O
ARG B:417 B:438 28.0 0.124 H -58.7 -58.0 28.0 0.124 0.0 HOH
 2.963
 NH2
 O
ARG C:417 C:438 29.0 0.129 H -62.6 -52.2 29.0 0.129 0.0 HOH
 2.841
 O
 O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ARG A:417 A:438 39.0 0.173 H -58.1 -42.0 39.0 0.173 0.0 HOH
 8.681
 N
 O
ARG B:417 B:438 35.0 0.156 H -62.4 -55.0 35.0 0.156 0.0
ARG C:417 C:438 26.0 0.116 H -62.0 -57.9 26.0 0.116 0.0 HOH
 6.569
 NH1
 O
ARG D:417 D:438 35.0 0.156 H -57.0 -47.2 NA NA NA
ARG E:417 E:438 53.0 0.236 H -56.8 -68.6 NA NA NA
ARG F:417 F:438 22.0 0.098 H -57.7 -59.2 NA NA NA
ARG G:417 G:438 31.0 0.138 H -61.9 -59.3 NA NA NA
ARG H:417 H:438 34.0 0.151 H -50.4 -42.7 NA NA NA
ARG I:417 I:438 40.0 0.178 H -68.7 -53.5 NA NA NA
ARG J:417 J:438 27.0 0.12 H -67.6 -60.2 NA NA NA
ARG K:417 K:438 39.0 0.173 H -71.0 -38.7 NA NA NA
ARG L:417 L:438 36.0 0.16 H -64.6 -55.6 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 ARG A:417 A:1438 31.0 0.138 H -63.5 -52.3 31.0 0.138 0.0 HOH
 6.597
 NH1
 O
ARG B:417 B:2438 27.0 0.12 H -63.1 -54.3 27.0 0.12 0.0 HOH
 3.313
 NH2
 O
ARG C:417 C:3438 26.0 0.116 H -52.9 -61.6 26.0 0.116 0.0 HOH
 2.842
 O
 O
ARG D:417 D:4438 28.0 0.124 H -65.5 -48.3 NA NA NA
ARG E:417 E:5438 29.0 0.129 H -63.1 -54.5 NA NA NA
ARG F:417 F:6438 26.0 0.116 H -55.3 -59.5 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 ARG A:417 A:1438 26.0 0.116 H -64.4 -50.1 26.0 0.116 0.0 HOH
 2.857
 O
 O
ARG B:417 B:2438 26.0 0.116 H -64.7 -56.4 26.0 0.116 0.0 HOH
 3.196
 NH2
 O
ARG C:417 C:3438 25.0 0.111 H -62.5 -56.4 25.0 0.111 0.0 HOH
 3.039
 O
 O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 ARG A:417 A:438 31.0 0.138 H -52.6 -50.9 31.0 0.138 0.0 HOH
 2.721
 O
 O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 ARG A:417 A:437 31.0 0.138 H -48.7 -48.7 31.0 0.138 0.0 HOH
 2.719
 O
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 ARG A:417 A:437 28.0 0.124 H -53.7 -44.7 28.0 0.124 0.0 HOH
 2.736
 NH2
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 ARG A:416 A:437 44.0 0.196 H -54.0 -52.9 44.0 0.196 0.0 HOH
 3.671
 CG
 O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 ARG A:414 A:1438 32.0 0.142 H -61.0 -43.0 32.0 0.142 0.0 HOH
 3.896
 O
 O
ARG B:414 B:2438 48.0 0.213 H -60.1 -42.5 48.0 0.213 0.0 HOH
 9.370
 CD
 O
ARG C:414 C:3438 49.0 0.218 H -59.7 -43.4 49.0 0.218 0.0
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 ARG A:415 A:437 29.0 0.129 H -58.5 -54.2 29.0 0.129 0.0 HOH
 2.855
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 ARG A:438 A:438 32.0 0.142 H -56.6 -48.0