Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55844441 . G A CCDS32450.1:NM_001025195.1:c.1306Cgg>Tgg_NP_001020366.1:p.436R>W Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 ARG A:416 A:1435 47.0 0.209 H -62.9 -42.4 47.0 0.209 0.0 HOH
 3.043
 NH1
 O
ARG B:416 B:2435 45.0 0.2 H -62.2 -39.8 45.0 0.2 0.0 HOH
 3.079
 NH1
 O
ARG C:416 C:3435 45.0 0.2 H -59.5 -47.9 45.0 0.2 0.0 HOH
 2.793
 NH1
 O
ARG D:416 D:4435 41.0 0.182 H -58.6 -43.7 41.0 0.182 0.0 HOH
 3.090
 NH1
 O
ARG E:416 E:5435 45.0 0.2 H -62.9 -45.2 45.0 0.2 0.0 HOH
 2.734
 NH1
 O
ARG F:416 F:6435 47.0 0.209 H -62.6 -40.1 47.0 0.209 0.0 HOH
 3.013
 NH1
 O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 ARG A:416 A:1435 45.0 0.2 H -62.3 -53.4 45.0 0.2 0.0 HOH
 3.051
 NE
 O
ARG B:416 B:2435 48.0 0.213 H -54.8 -47.7 48.0 0.213 0.0 HOH
 3.085
 NH2
 O
ARG C:416 C:3435 47.0 0.209 H -54.9 -45.4 47.0 0.209 0.0 HOH
 2.802
 NH1
 O
ARG D:416 D:4435 45.0 0.2 H -52.5 -51.6 NA NA NA
ARG E:416 E:5435 44.0 0.196 H -58.9 -46.9 NA NA NA
ARG F:416 F:6435 45.0 0.2 H -64.8 -47.3 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 ARG A:416 A:1435 45.0 0.2 H -58.0 -48.5 45.0 0.2 0.0 HOH
 4.191
 NH2
 O
ARG B:416 B:2435 47.0 0.209 H -58.1 -51.7 47.0 0.209 0.0 HOH
 3.532
 NE
 O
ARG C:416 C:3435 45.0 0.2 H -67.8 -47.9 45.0 0.2 0.0 HOH
 2.398
 NH2
 O
ARG D:416 D:4435 38.0 0.169 H -61.4 -44.8 38.0 0.169 0.0 HOH
 3.176
 NH1
 O
ARG E:416 E:5435 43.0 0.191 H -58.6 -44.4 43.0 0.191 0.0 HOH
 3.136
 NH1
 O
ARG F:416 F:6435 41.0 0.182 H -63.9 -57.3 41.0 0.182 0.0 HOH
 3.672
 NH2
 O
ARG G:416 G:1435 46.0 0.204 H -52.3 -61.9 NA NA NA
ARG H:416 H:2435 47.0 0.209 H -64.2 -48.5 NA NA NA
ARG I:416 I:3435 47.0 0.209 H -55.6 -67.4 NA NA NA
ARG J:416 J:4435 45.0 0.2 H -71.3 -43.4 NA NA NA
ARG K:416 K:5435 47.0 0.209 H -48.2 -50.4 NA NA NA
ARG L:416 L:6435 45.0 0.2 H -58.9 -64.7 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ARG A:416 A:1435 46.0 0.204 H -61.3 -50.0 46.0 0.204 0.0 HOH
 3.325
 NH2
 O
ARG B:416 B:2435 44.0 0.196 H -61.1 -51.9 44.0 0.196 0.0 HOH
 3.158
 NH1
 O
ARG C:416 C:3435 47.0 0.209 H -62.0 -50.3 47.0 0.209 0.0 HOH
 3.821
 NH2
 O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ARG A:416 A:1435 46.0 0.204 H -56.3 -44.1 46.0 0.204 0.0 HOH
 3.698
 C
 O
ARG B:416 B:2435 47.0 0.209 H -66.4 -48.2 47.0 0.209 0.0 HOH
 4.247
 NH2
 O
ARG C:416 C:3435 47.0 0.209 H -58.6 -33.1 47.0 0.209 0.0 PLM
HOH
 9.672
3.896
 NH1
NE
 C8
O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ARG A:416 A:1435 42.0 0.187 H -62.9 -52.5 42.0 0.187 0.0 HOH
 9.279
 NH2
 O
ARG B:416 B:2435 43.0 0.191 H -63.4 -53.4 43.0 0.191 0.0 HOH
 9.661
 N
 O
ARG C:416 C:3435 44.0 0.196 H -62.2 -52.5 44.0 0.196 0.0 HOH
 3.379
 NH1
 O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ARG A:416 A:1435 45.0 0.2 H -63.5 -41.3 45.0 0.2 0.0 HOH
 2.927
 NH1
 O
ARG B:416 B:2435 47.0 0.209 H -59.3 -43.9 47.0 0.209 0.0 HOH
 3.035
 NH1
 O
ARG C:416 C:3435 47.0 0.209 H -63.2 -43.3 47.0 0.209 0.0 HOH
 2.810
 NH1
 O
ARG D:416 D:4435 43.0 0.191 H -60.8 -45.1 43.0 0.191 0.0 HOH
 2.872
 NH1
 O
ARG E:416 E:5435 43.0 0.191 H -59.7 -44.0 43.0 0.191 0.0 HOH
 2.771
 NH1
 O
ARG F:416 F:6435 46.0 0.204 H -62.7 -40.2 46.0 0.204 0.0 HOH
 2.935
 NH1
 O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ARG A:414 A:435 42.0 0.187 H -59.1 -52.1 42.0 0.187 0.0 HOH
 3.419
 NH2
 O
ARG B:414 B:435 41.0 0.182 H -59.6 -52.5 41.0 0.182 0.0 HOH
 4.650
 NH2
 O
ARG C:414 C:435 42.0 0.187 H -57.3 -48.1 42.0 0.187 0.0 HOH
 6.503
 C
 O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ARG A:414 A:435 50.0 0.222 H -56.5 -53.5 50.0 0.222 0.0 HOH
 4.316
 NH2
 O
ARG B:414 B:435 46.0 0.204 H -58.0 -56.6 46.0 0.204 0.0 HOH
 2.569
 NH1
 O
ARG C:414 C:435 47.0 0.209 H -61.3 -56.9 47.0 0.209 0.0 HOH
 6.614
 O
 O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ARG A:414 A:435 44.0 0.196 H -60.0 -45.7 44.0 0.196 0.0 HOH
 3.043
 NH1
 O
ARG B:414 B:435 44.0 0.196 H -62.0 -47.1 44.0 0.196 0.0 HOH
 2.834
 NH2
 O
ARG C:414 C:435 44.0 0.196 H -55.5 -50.0 44.0 0.196 0.0 HOH
 2.449
 NH1
 O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ARG A:414 A:435 45.0 0.2 H -72.1 -36.0 45.0 0.2 0.0 HOH
 9.919
 N
 O
ARG B:414 B:435 38.0 0.169 H -54.4 -51.6 38.0 0.169 0.0
ARG C:414 C:435 49.0 0.218 H -59.9 -33.3 49.0 0.218 0.0 HOH
 3.515
 NH2
 O
ARG D:414 D:435 44.0 0.196 H -67.2 -35.4 NA NA NA
ARG E:414 E:435 47.0 0.209 H -47.4 -44.7 NA NA NA
ARG F:414 F:435 40.0 0.178 H -71.5 -34.0 NA NA NA
ARG G:414 G:435 45.0 0.2 H -56.3 -31.3 NA NA NA
ARG H:414 H:435 41.0 0.182 H -48.3 -48.6 NA NA NA
ARG I:414 I:435 38.0 0.169 H -50.8 -54.6 NA NA NA
ARG J:414 J:435 46.0 0.204 H -58.4 -33.9 NA NA NA
ARG K:414 K:435 48.0 0.213 H -55.7 -47.7 NA NA NA
ARG L:414 L:435 44.0 0.196 H -60.9 -51.9 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 ARG A:414 A:1435 43.0 0.191 H -59.7 -49.1 43.0 0.191 0.0 HOH
 3.702
 NH2
 O
ARG B:414 B:2435 44.0 0.196 H -60.2 -50.0 44.0 0.196 0.0 HOH
 3.075
 NH1
 O
ARG C:414 C:3435 46.0 0.204 H -60.1 -44.9 46.0 0.204 0.0 HOH
 2.792
 NH1
 O
ARG D:414 D:4435 48.0 0.213 H -53.6 -47.0 NA NA NA
ARG E:414 E:5435 41.0 0.182 H -62.4 -51.8 NA NA NA
ARG F:414 F:6435 46.0 0.204 H -67.3 -40.4 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 ARG A:414 A:1435 44.0 0.196 H -53.7 -47.3 44.0 0.196 0.0 HOH
 3.049
 NH1
 O
ARG B:414 B:2435 45.0 0.2 H -60.8 -46.9 45.0 0.2 0.0 HOH
 2.856
 NH1
 O
ARG C:414 C:3435 47.0 0.209 H -61.8 -38.1 47.0 0.209 0.0 HOH
 2.592
 NH1
 O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 ARG A:414 A:435 41.0 0.182 H -65.8 -45.7 41.0 0.182 0.0 HOH
 3.008
 NH1
 O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 ARG A:414 A:434 43.0 0.191 H -61.5 -46.8 43.0 0.191 0.0 HOH
 2.819
 NH1
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 ARG A:414 A:434 42.0 0.187 H -62.3 -42.3 42.0 0.187 0.0 HOH
 2.859
 NH1
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 ARG A:413 A:434 41.0 0.182 H -59.8 -45.3 41.0 0.182 0.0 HOH
 2.742
 NH1
 O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 ARG A:411 A:1435 39.0 0.173 H -66.7 -47.9 39.0 0.173 0.0 HOH
 8.185
 O
 O
ARG B:411 B:2435 38.0 0.169 H -66.1 -49.3 38.0 0.169 0.0
ARG C:411 C:3435 38.0 0.169 H -66.9 -48.7 38.0 0.169 0.0
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 ARG A:412 A:434 45.0 0.2 H -47.9 -43.3 45.0 0.2 0.0 HOH
 2.725
 NE
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 ARG A:435 A:435 42.0 0.187 H -61.3 -48.8