Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55844446 . A C CCDS32450.1:NM_001025195.1:c.1301gTg>gGg_NP_001020366.1:p.434V>G Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 VAL A:414 A:1433 6.0 0.039 H -65.4 -47.1 6.0 0.039 0.0 HOH
 2.679
 O
 O
VAL B:414 B:2433 7.0 0.045 H -65.6 -40.4 7.0 0.045 0.0 HOH
 2.924
 O
 O
VAL C:414 C:3433 7.0 0.045 H -69.0 -38.5 7.0 0.045 0.0 HOH
 2.833
 O
 O
VAL D:414 D:4433 6.0 0.039 H -61.4 -37.7 6.0 0.039 0.0 HOH
 2.722
 O
 O
VAL E:414 E:5433 7.0 0.045 H -63.4 -44.9 7.0 0.045 0.0 HOH
 2.984
 O
 O
VAL F:414 F:6433 11.0 0.071 H -69.9 -41.4 11.0 0.071 0.0 HOH
 2.805
 O
 O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 VAL A:414 A:1433 8.0 0.052 H -57.3 -44.6 8.0 0.052 0.0 HOH
 2.961
 O
 O
VAL B:414 B:2433 7.0 0.045 H -59.6 -54.9 7.0 0.045 0.0 HOH
 2.940
 O
 O
VAL C:414 C:3433 2.0 0.013 H -54.9 -47.2 2.0 0.013 0.0 HOH
 4.031
 CG1
 O
VAL D:414 D:4433 8.0 0.052 H -58.8 -56.6 NA NA NA
VAL E:414 E:5433 4.0 0.026 H -52.2 -41.7 NA NA NA
VAL F:414 F:6433 3.0 0.019 H -63.1 -41.5 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 VAL A:414 A:1433 7.0 0.045 H -59.6 -39.9 7.0 0.045 0.0 HOH
 9.541
 CG2
 O
VAL B:414 B:2433 6.0 0.039 H -58.0 -39.1 6.0 0.039 0.0 HOH
 3.924
 CG1
 O
VAL C:414 C:3433 1.0 0.006 H -52.4 -44.2 1.0 0.006 0.0 HOH
 3.586
 CG1
 O
VAL D:414 D:4433 7.0 0.045 H -46.6 -51.4 7.0 0.045 0.0 HOH
 4.250
 CG1
 O
VAL E:414 E:5433 2.0 0.013 H -65.9 -42.2 2.0 0.013 0.0 HOH
 4.373
 CG1
 O
VAL F:414 F:6433 4.0 0.026 H -62.7 -55.5 4.0 0.026 0.0 HOH
 7.487
 CG2
 O
VAL G:414 G:1433 5.0 0.032 H -57.8 -65.6 NA NA NA
VAL H:414 H:2433 3.0 0.019 H -55.6 -50.6 NA NA NA
VAL I:414 I:3433 5.0 0.032 H -52.4 -52.3 NA NA NA
VAL J:414 J:4433 7.0 0.045 H -52.9 -32.1 NA NA NA
VAL K:414 K:5433 4.0 0.026 H -48.5 -53.3 NA NA NA
VAL L:414 L:6433 5.0 0.032 H -56.7 -51.3 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 VAL A:414 A:1433 9.0 0.058 H -63.1 -45.5 9.0 0.058 0.0 HOH
 3.624
 CG1
 O
VAL B:414 B:2433 9.0 0.058 H -62.3 -45.4 9.0 0.058 0.0 HOH
 3.692
 CG1
 O
VAL C:414 C:3433 9.0 0.058 H -62.4 -47.3 9.0 0.058 0.0 HOH
 4.114
 CG1
 O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 VAL A:414 A:1433 10.0 0.065 H -57.5 -41.5 10.0 0.065 0.0 HOH
 3.991
 CG1
 O
VAL B:414 B:2433 7.0 0.045 H -55.0 -40.9 7.0 0.045 0.0 HOH
 2.680
 O
 O
VAL C:414 C:3433 9.0 0.058 H -63.1 -39.2 9.0 0.058 0.0 PLM
HOH
 7.989
3.065
 N
O
 C6
O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 VAL A:414 A:1433 8.0 0.052 H -53.1 -53.1 8.0 0.052 0.0 HOH
 4.183
 CG1
 O
VAL B:414 B:2433 7.0 0.045 H -52.9 -51.7 7.0 0.045 0.0 HOH
 4.324
 CG1
 O
VAL C:414 C:3433 9.0 0.058 H -53.9 -52.8 9.0 0.058 0.0 HOH
 7.089
 CB
 O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 VAL A:414 A:1433 11.0 0.071 H -60.8 -43.1 11.0 0.071 0.0 HOH
 2.758
 O
 O
VAL B:414 B:2433 5.0 0.032 H -63.7 -45.2 5.0 0.032 0.0 HOH
 2.843
 O
 O
VAL C:414 C:3433 8.0 0.052 H -67.8 -38.8 8.0 0.052 0.0 HOH
 2.845
 O
 O
VAL D:414 D:4433 9.0 0.058 H -64.1 -42.9 9.0 0.058 0.0 HOH
 2.952
 O
 O
VAL E:414 E:5433 7.0 0.045 H -66.6 -44.2 7.0 0.045 0.0 HOH
 2.749
 O
 O
VAL F:414 F:6433 6.0 0.039 H -70.0 -42.7 6.0 0.039 0.0 HOH
 2.866
 O
 O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 VAL A:412 A:433 12.0 0.077 H -65.0 -39.6 12.0 0.077 0.0 HOH
 7.199
 CB
 O
VAL B:412 B:433 12.0 0.077 H -62.2 -39.5 12.0 0.077 0.0 HOH
 3.711
 CG1
 O
VAL C:412 C:433 11.0 0.071 H -67.5 -41.5 11.0 0.071 0.0 HOH
 3.871
 O
 O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 VAL A:412 A:433 0.0 0.0 H -54.4 -52.1 0.0 0.0 0.0 HOH
 4.126
 CG1
 O
VAL B:412 B:433 12.0 0.077 H -49.6 -48.9 12.0 0.077 0.0 HOH
 4.285
 CG1
 O
VAL C:412 C:433 2.0 0.013 H -59.1 -57.2 2.0 0.013 0.0 HOH
 4.109
 CG1
 O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 VAL A:412 A:433 5.0 0.032 H -54.4 -49.8 5.0 0.032 0.0 HOH
 2.944
 CG2
 O
VAL B:412 B:433 7.0 0.045 H -53.9 -47.6 7.0 0.045 0.0 HOH
 2.943
 O
 O
VAL C:412 C:433 8.0 0.052 H -59.5 -47.3 8.0 0.052 0.0 HOH
 3.212
 O
 O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 VAL A:412 A:433 5.0 0.032 H -68.1 -40.9 5.0 0.032 0.0 HOH
 6.540
 CB
 O
VAL B:412 B:433 3.0 0.019 H -74.6 -35.3 3.0 0.019 0.0 HOH
 7.852
 CB
 O
VAL C:412 C:433 5.0 0.032 H -66.1 -42.5 5.0 0.032 0.0 HOH
 7.516
 CB
 O
VAL D:412 D:433 3.0 0.019 H -67.7 -38.4 NA NA NA
VAL E:412 E:433 7.0 0.045 H -56.3 -32.9 NA NA NA
VAL F:412 F:433 7.0 0.045 H -63.5 -45.9 NA NA NA
VAL G:412 G:433 6.0 0.039 H -68.6 -50.0 NA NA NA
VAL H:412 H:433 8.0 0.052 H -52.0 -40.0 NA NA NA
VAL I:412 I:433 6.0 0.039 H -56.9 -32.9 NA NA NA
VAL J:412 J:433 4.0 0.026 H -70.2 -44.3 NA NA NA
VAL K:412 K:433 1.0 0.006 H -54.2 -49.6 NA NA NA
VAL L:412 L:433 5.0 0.032 H -64.5 -33.6 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 VAL A:412 A:1433 5.0 0.032 H -58.5 -43.3 5.0 0.032 0.0 HOH
 3.865
 CG1
 O
VAL B:412 B:2433 5.0 0.032 H -56.2 -48.2 5.0 0.032 0.0 HOH
 3.011
 O
 O
VAL C:412 C:3433 7.0 0.045 H -67.1 -54.1 7.0 0.045 0.0 HOH
 3.343
 O
 O
VAL D:412 D:4433 7.0 0.045 H -56.7 -49.8 NA NA NA
VAL E:412 E:5433 4.0 0.026 H -57.8 -50.2 NA NA NA
VAL F:412 F:6433 7.0 0.045 H -69.9 -43.8 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 VAL A:412 A:1433 2.0 0.013 H -58.2 -42.9 2.0 0.013 0.0 HOH
 3.741
 CG1
 O
VAL B:412 B:2433 5.0 0.032 H -60.2 -49.7 5.0 0.032 0.0 HOH
 3.193
 O
 O
VAL C:412 C:3433 6.0 0.039 H -67.8 -40.5 6.0 0.039 0.0 HOH
 3.822
 CG1
 O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 VAL A:412 A:433 21.0 0.135 H -58.5 -48.9 21.0 0.135 0.0 SCN
HOH
 8.611
3.861
 CG2
CG1
 S
O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 VAL A:412 A:432 6.0 0.039 H -59.9 -45.3 6.0 0.039 0.0 HOH
 3.251
 O
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 VAL A:412 A:432 8.0 0.052 H -63.0 -47.2 8.0 0.052 0.0 HOH
 2.953
 O
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 VAL A:411 A:432 5.0 0.032 H -61.2 -48.7 5.0 0.032 0.0 HOH
 2.921
 O
 O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 VAL A:409 A:1433 3.0 0.019 H -73.4 -59.2 3.0 0.019 0.0 HOH
 7.600
 CB
 O
VAL B:409 B:2433 4.0 0.026 H -72.8 -58.7 4.0 0.026 0.0
VAL C:409 C:3433 2.0 0.013 H -71.8 -59.8 2.0 0.013 0.0
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 VAL A:410 A:432 1.0 0.006 H -66.6 -43.6 1.0 0.006 0.0 HOH
 6.747
 CB
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 VAL A:433 A:433 2.0 0.013 H -59.8 -46.9