Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55844449 . A C CCDS32450.1:NM_001025195.1:c.1298aTt>aGt_NP_001020366.1:p.433I>S Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 ILE A:413 A:1432 42.0 0.24 H -60.1 -41.2 42.0 0.24 0.0 HOH
 3.666
 CG2
 O
ILE B:413 B:2432 41.0 0.234 H -58.2 -42.7 41.0 0.234 0.0 HOH
 4.007
 CD1
 O
ILE C:413 C:3432 44.0 0.251 H -59.9 -39.9 44.0 0.251 0.0 HOH
 3.833
 CD1
 O
ILE D:413 D:4432 45.0 0.257 H -61.6 -44.9 45.0 0.257 0.0 HOH
 3.817
 CD1
 O
ILE E:413 E:5432 40.0 0.229 H -62.4 -43.9 40.0 0.229 0.0 HOH
 3.752
 CD1
 O
ILE F:413 F:6432 45.0 0.257 H -63.4 -37.8 45.0 0.257 0.0 HOH
 3.706
 CD1
 O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 ILE A:413 A:1432 39.0 0.223 H -60.2 -50.7 39.0 0.223 0.0 HOH
 3.989
 CG1
 O
ILE B:413 B:2432 43.0 0.246 H -60.0 -41.5 43.0 0.246 0.0 HOH
 3.265
 CD1
 O
ILE C:413 C:3432 40.0 0.229 H -52.1 -53.6 40.0 0.229 0.0 HOH
 3.948
 CG1
 O
ILE D:413 D:4432 44.0 0.251 H -65.3 -40.4 NA NA NA
ILE E:413 E:5432 44.0 0.251 H -58.6 -52.2 NA NA NA
ILE F:413 F:6432 46.0 0.263 H -59.8 -48.2 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 ILE A:413 A:1432 48.0 0.274 H -60.2 -46.6 48.0 0.274 0.0 HOH
 6.283
 CD1
 O
ILE B:413 B:2432 42.0 0.24 H -67.1 -54.5 42.0 0.24 0.0 HOH
 6.098
 CD1
 O
ILE C:413 C:3432 42.0 0.24 H -63.7 -54.0 42.0 0.24 0.0 HOH
 7.636
 N
 O
ILE D:413 D:4432 44.0 0.251 H -55.6 -56.7 44.0 0.251 0.0 HOH
 6.014
 CD1
 O
ILE E:413 E:5432 46.0 0.263 H -69.0 -38.2 46.0 0.263 0.0 HOH
 3.924
 CG1
 O
ILE F:413 F:6432 45.0 0.257 H -57.2 -44.1 45.0 0.257 0.0 HOH
 7.350
 N
 O
ILE G:413 G:1432 50.0 0.286 H -50.6 -48.2 NA NA NA
ILE H:413 H:2432 49.0 0.28 H -55.7 -51.7 NA NA NA
ILE I:413 I:3432 49.0 0.28 H -58.6 -58.7 NA NA NA
ILE J:413 J:4432 45.0 0.257 H -61.7 -54.8 NA NA NA
ILE K:413 K:5432 40.0 0.229 H -71.6 -56.9 NA NA NA
ILE L:413 L:6432 44.0 0.251 H -54.7 -47.3 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ILE A:413 A:1432 48.0 0.274 H -57.2 -44.0 48.0 0.274 0.0 HOH
 7.447
 N
 O
ILE B:413 B:2432 48.0 0.274 H -56.4 -45.4 48.0 0.274 0.0 HOH
 5.331
 CG2
 O
ILE C:413 C:3432 47.0 0.269 H -55.7 -44.9 47.0 0.269 0.0 HOH
 6.461
 CG2
 O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ILE A:413 A:1432 40.0 0.229 H -59.2 -48.2 40.0 0.229 0.0 HOH
 4.720
 O
 O
ILE B:413 B:2432 48.0 0.274 H -56.6 -53.9 48.0 0.274 0.0 HOH
 4.663
 O
 O
ILE C:413 C:3432 39.0 0.223 H -56.1 -44.4 39.0 0.223 0.0 PLM
HOH
 3.690
3.748
 CD1
CD1
 C6
O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ILE A:413 A:1432 43.0 0.246 H -60.5 -48.3 43.0 0.246 0.0 HOH
 6.463
 CD1
 O
ILE B:413 B:2432 44.0 0.251 H -60.0 -49.6 44.0 0.251 0.0 HOH
 8.549
 C
 O
ILE C:413 C:3432 44.0 0.251 H -60.3 -48.6 44.0 0.251 0.0 HOH
 7.290
 CG1
 O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 ILE A:413 A:1432 40.0 0.229 H -63.5 -45.4 40.0 0.229 0.0 HOH
 3.547
 CD1
 O
ILE B:413 B:2432 42.0 0.24 H -63.0 -42.8 42.0 0.24 0.0 HOH
 2.571
 O
 O
ILE C:413 C:3432 42.0 0.24 H -62.7 -42.5 42.0 0.24 0.0 HOH
 3.255
 CD1
 O
ILE D:413 D:4432 43.0 0.246 H -65.4 -42.1 43.0 0.246 0.0 HOH
 3.515
 CG2
 O
ILE E:413 E:5432 42.0 0.24 H -59.3 -40.5 42.0 0.24 0.0 HOH
 3.738
 CD1
 O
ILE F:413 F:6432 44.0 0.251 H -64.5 -36.4 44.0 0.251 0.0 HOH
 3.494
 CD1
 O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ILE A:411 A:432 43.0 0.246 H -61.0 -41.9 43.0 0.246 0.0 HOH
 6.847
 N
 O
ILE B:411 B:432 43.0 0.246 H -63.8 -43.7 43.0 0.246 0.0 HOH
 7.742
 N
 O
ILE C:411 C:432 43.0 0.246 H -58.1 -40.4 43.0 0.246 0.0 HOH
 4.090
 CG2
 O
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ILE A:411 A:432 52.0 0.297 H -60.6 -49.9 52.0 0.297 0.0 HOH
 6.461
 CD1
 O
ILE B:411 B:432 43.0 0.246 H -57.5 -55.5 43.0 0.246 0.0 HOH
 6.788
 CG1
 O
ILE C:411 C:432 44.0 0.251 H -54.0 -42.8 44.0 0.251 0.0 HOH
 4.593
 CG2
 O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ILE A:411 A:432 48.0 0.274 H -67.5 -48.8 48.0 0.274 0.0 HOH
 5.060
 O
 O
ILE B:411 B:432 46.0 0.263 H -63.6 -49.9 46.0 0.263 0.0 HOH
 4.888
 O
 O
ILE C:411 C:432 42.0 0.24 H -63.0 -42.5 42.0 0.24 0.0 HOH
 4.279
 CG1
 O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 ILE A:411 A:432 46.0 0.263 H -61.8 -37.9 46.0 0.263 0.0 HOH
 8.277
 N
 O
ILE B:411 B:432 48.0 0.274 H -62.0 -33.3 48.0 0.274 0.0 HOH
 9.608
 N
 O
ILE C:411 C:432 43.0 0.246 H -48.7 -36.3 43.0 0.246 0.0 HOH
 8.847
 CG1
 O
ILE D:411 D:432 50.0 0.286 H -59.4 -38.0 NA NA NA
ILE E:411 E:432 46.0 0.263 H -62.0 -47.4 NA NA NA
ILE F:411 F:432 40.0 0.229 H -50.8 -39.3 NA NA NA
ILE G:411 G:432 42.0 0.24 H -53.3 -26.7 NA NA NA
ILE H:411 H:432 44.0 0.251 H -61.8 -48.8 NA NA NA
ILE I:411 I:432 48.0 0.274 H -49.6 -50.2 NA NA NA
ILE J:411 J:432 39.0 0.223 H -58.2 -24.7 NA NA NA
ILE K:411 K:432 46.0 0.263 H -69.9 -48.0 NA NA NA
ILE L:411 L:432 51.0 0.291 H -57.7 -45.7 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 ILE A:411 A:1432 48.0 0.274 H -66.6 -46.9 48.0 0.274 0.0 HOH
 5.487
 CD1
 O
ILE B:411 B:2432 42.0 0.24 H -59.7 -48.9 42.0 0.24 0.0 HOH
 3.836
 CG1
 O
ILE C:411 C:3432 41.0 0.234 H -64.1 -37.0 41.0 0.234 0.0 HOH
 3.489
 CD1
 O
ILE D:411 D:4432 47.0 0.269 H -63.3 -46.6 NA NA NA
ILE E:411 E:5432 43.0 0.246 H -56.9 -47.5 NA NA NA
ILE F:411 F:6432 43.0 0.246 H -60.9 -37.1 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 ILE A:411 A:1432 45.0 0.257 H -63.7 -47.9 45.0 0.257 0.0 HOH
 4.592
 CG2
 O
ILE B:411 B:2432 43.0 0.246 H -59.8 -46.7 43.0 0.246 0.0 HOH
 4.073
 CG1
 O
ILE C:411 C:3432 40.0 0.229 H -61.6 -39.1 40.0 0.229 0.0 HOH
 3.740
 CD1
 O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 ILE A:411 A:432 43.0 0.246 H -61.2 -44.4 43.0 0.246 0.0 SCN
HOH
 9.471
4.108
 CG2
CG1
 N
O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 ILE A:411 A:431 39.0 0.223 H -60.2 -45.1 39.0 0.223 0.0 HOH
 3.789
 CG2
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 ILE A:411 A:431 40.0 0.229 H -61.5 -42.1 40.0 0.229 0.0 HOH
 3.565
 CG2
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 ILE A:410 A:431 39.0 0.223 H -58.5 -47.1 39.0 0.223 0.0 HOH
 3.678
 CD1
 O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 ILE A:408 A:1432 47.0 0.269 H -54.8 -32.0 47.0 0.269 0.0 HOH
 6.944
 CD1
 O
ILE B:408 B:2432 39.0 0.223 H -55.7 -32.3 39.0 0.223 0.0
ILE C:408 C:3432 48.0 0.274 H -54.2 -33.4 48.0 0.274 0.0 HOH
 9.342
 CD1
 O
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 ASN A:409 A:431 47.0 0.294 H -60.2 -40.5 47.0 0.294 0.0 MAN
4PN
HOH
 9.028
6.819
3.595
 OD1
OD1
OD1
 O4
C8
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 ILE A:432 A:432 48.0 0.274 H -62.7 -45.7