Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55844530 . C A CCDS32450.1:NM_001025195.1:c.1217gGa>gTa_NP_001020366.1:p.406G>V Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 GLY A:386 A:1405 29.0 0.387 T -60.6 -18.5 29.0 0.387 0.0 HOH
 3.816
 N
 O
GLY B:386 B:2405 23.0 0.307 T -60.9 -35.4 23.0 0.307 0.0 HOH
 3.383
 O
 O
GLY C:386 C:3405 27.0 0.36 T -53.9 -11.3 27.0 0.36 0.0 HOH
 4.000
 C
 O
GLY D:386 D:4405 31.0 0.413 S -69.8 -3.7 31.0 0.413 0.0 HOH
 3.620
 N
 O
GLY E:386 E:5405 26.0 0.347 T -49.6 -39.6 26.0 0.347 0.0 HOH
 3.533
 N
 O
GLY F:386 F:6405 29.0 0.387 S -66.3 -6.4 29.0 0.387 0.0 HOH
 3.124
 CA
 O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 GLY A:386 A:1405 37.0 0.493 S -73.5 0.7 37.0 0.493 0.0 HOH
 2.963
 O
 O
GLY B:386 B:2405 37.0 0.493 T -61.5 7.1 37.0 0.493 0.0 HOH
 8.636
 O
 O
GLY C:386 C:3405 21.0 0.28 T -54.2 -21.3 21.0 0.28 0.0 HOH
 7.588
 CA
 O
GLY D:386 D:4405 37.0 0.493 T -63.6 14.1 NA NA NA
GLY E:386 E:5405 28.0 0.373 T -59.8 -21.3 NA NA NA
GLY F:386 F:6405 29.0 0.387 T -65.2 -16.9 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 GLY A:386 A:1405 23.0 0.307 S -83.1 -59.8 23.0 0.307 0.0
GLY B:386 B:2405 24.0 0.32 T -60.5 -0.3 24.0 0.32 0.0 HOH
 6.016
 O
 O
GLY C:386 C:3405 30.0 0.4 T -55.3 18.0 30.0 0.4 0.0 HOH
 5.668
 C
 O
GLY D:386 D:4405 31.0 0.413 T -52.9 -7.9 31.0 0.413 0.0 HOH
 5.031
 O
 O
GLY E:386 E:5405 29.0 0.387 S -69.6 -9.0 29.0 0.387 0.0 HOH
 8.323
 CA
 O
GLY F:386 F:6405 36.0 0.48 T -70.5 -8.0 36.0 0.48 0.0 HOH
 7.121
 O
 O
GLY G:386 G:1405 31.0 0.413 S -73.0 -6.4 NA NA NA
GLY H:386 H:2405 28.0 0.373 S -64.6 -46.6 NA NA NA
GLY I:386 I:3405 33.0 0.44 S -89.0 -11.8 NA NA NA
GLY J:386 J:4405 32.0 0.427 T -58.0 -10.1 NA NA NA
GLY K:386 K:5405 30.0 0.4 T -68.8 11.1 NA NA NA
GLY L:386 L:6405 41.0 0.547 S -78.8 26.8 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:386 A:1405 31.0 0.413 S -56.5 -6.2 31.0 0.413 0.0
GLY B:386 B:2405 30.0 0.4 T -56.6 -6.4 30.0 0.4 0.0 HOH
 7.519
 O
 O
GLY C:386 C:3405 30.0 0.4 S -56.7 -6.3 30.0 0.4 0.0 HOH
 6.252
 N
 O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:386 A:1405 38.0 0.507 S -63.0 -6.7 38.0 0.507 0.0 HOH
 9.985
 C
 O
GLY B:386 B:2405 41.0 0.547 S -71.7 35.1 41.0 0.547 0.0 HOH
 8.476
 N
 O
GLY C:386 C:3405 32.0 0.427 S -69.0 -0.8 32.0 0.427 0.0 HOH
 7.875
 CA
 O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:386 A:1405 35.0 0.467 S -57.6 -1.8 35.0 0.467 0.0 HOH
 3.026
 CA
 O
GLY B:386 B:2405 35.0 0.467 S -57.6 -1.9 35.0 0.467 0.0 HOH
 3.197
 CA
 O
GLY C:386 C:3405 35.0 0.467 S -56.8 -1.9 35.0 0.467 0.0 HOH
 8.502
 O
 O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 GLY A:386 A:1405 13.0 0.173 S -44.6 -80.0 13.0 0.173 0.0 HOH
 2.533
 O
 O
GLY B:386 B:2405 28.0 0.373 T -63.5 -5.3 28.0 0.373 0.0 HOH
 3.598
 N
 O
GLY C:386 C:3405 31.0 0.413 T -66.3 -2.7 31.0 0.413 0.0 HOH
 3.535
 C
 O
GLY D:386 D:4405 17.0 0.227 S -44.5 -20.4 17.0 0.227 0.0 HOH
 4.621
 C
 O
GLY E:386 E:5405 29.0 0.387 T -60.3 -5.5 29.0 0.387 0.0 HOH
 3.224
 C
 O
GLY F:386 F:6405 38.0 0.507 T -58.4 12.2 38.0 0.507 0.0 HOH
 7.447
 CA
 O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:384 A:405 33.0 0.44 S -60.2 -12.4 33.0 0.44 0.0
GLY B:384 B:405 35.0 0.467 S -61.5 -15.3 35.0 0.467 0.0 HOH
 9.801
 N
 O
GLY C:384 C:405 33.0 0.44 S -63.5 -8.9 33.0 0.44 0.0
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:384 A:405 34.0 0.453 T -77.7 10.3 34.0 0.453 0.0 HOH
 8.920
 N
 O
GLY B:384 B:405 32.0 0.427 T -89.6 -5.5 32.0 0.427 0.0 HOH
 7.037
 C
 O
GLY C:384 C:405 36.0 0.48 T -62.9 -8.4 36.0 0.48 0.0 HOH
 7.185
 O
 O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:384 A:405 31.0 0.413 T -67.3 -5.7 31.0 0.413 0.0 HOH
 6.956
 C
 O
GLY B:384 B:405 32.0 0.427 T -69.5 -4.5 32.0 0.427 0.0 HOH
 9.394
 N
 O
GLY C:384 C:405 30.0 0.4 T -65.1 -8.0 30.0 0.4 0.0 HOH
 8.401
 O
 O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 GLY A:384 A:405 41.0 0.547 T -71.3 -6.4 41.0 0.547 0.0
GLY B:384 B:405 22.0 0.293 T -62.8 -6.1 22.0 0.293 0.0
GLY C:384 C:405 35.0 0.467 S -63.7 1.9 35.0 0.467 0.0
GLY D:384 D:405 31.0 0.413 S -68.9 -12.1 NA NA NA
GLY E:384 E:405 36.0 0.48 T -56.3 -4.7 NA NA NA
GLY F:384 F:405 29.0 0.387 T -45.7 -15.5 NA NA NA
GLY G:384 G:405 28.0 0.373 T -58.8 -11.2 NA NA NA
GLY H:384 H:405 31.0 0.413 T -103.3 4.5 NA NA NA
GLY I:384 I:405 34.0 0.453 T -67.8 -1.3 NA NA NA
GLY J:384 J:405 37.0 0.493 T -71.0 10.9 NA NA NA
GLY K:384 K:405 28.0 0.373 T -72.1 -16.1 NA NA NA
GLY L:384 L:405 33.0 0.44 T -72.0 19.5 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 GLY A:384 A:1405 24.0 0.32 T -53.7 -30.8 24.0 0.32 0.0 HOH
 7.036
 O
 O
GLY B:384 B:2405 28.0 0.373 T -55.7 -11.0 28.0 0.373 0.0
GLY C:384 C:3405 29.0 0.387 T -53.1 -20.9 29.0 0.387 0.0 HOH
 3.830
 N
 O
GLY D:384 D:4405 28.0 0.373 T -58.7 3.9 NA NA NA
GLY E:384 E:5405 29.0 0.387 T -59.8 -4.0 NA NA NA
GLY F:384 F:6405 30.0 0.4 T -52.8 -13.4 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 GLY A:384 A:1405 34.0 0.453 I -55.0 -55.9 34.0 0.453 0.0
GLY B:384 B:2405 37.0 0.493 S -61.6 -39.6 37.0 0.493 0.0 HOH
 3.686
 N
 O
GLY C:384 C:3405 26.0 0.347 T -51.5 -31.3 26.0 0.347 0.0 HOH
 3.947
 C
 O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 GLY A:384 A:405 36.0 0.48 T -72.0 -8.5 36.0 0.48 0.0 HOH
 6.089
 CA
 O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 GLY A:384 A:404 25.0 0.333 T -70.9 -10.4 25.0 0.333 0.0 HOH
 3.463
 N
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 GLY A:384 A:404 20.0 0.267 T -70.5 -20.7 20.0 0.267 0.0 HOH
 2.868
 O
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 GLY A:383 A:404 27.0 0.36 T -74.5 -25.3 27.0 0.36 0.0 HOH
 3.579
 N
 O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 GLY A:381 A:1405 86.0 1.0 -64.6 360.0 86.0 1.0 0.0
GLY B:381 B:2405 53.0 0.707 T -63.8 -53.7 53.0 0.707 0.0
GLY C:381 C:3405 34.0 0.453 T -62.8 -55.0 34.0 0.453 0.0
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 GLY A:382 A:404 3.0 0.04 I -37.2 175.2 3.0 0.04 0.0 HOH
 3.439
 C
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 GLY A:405 A:405 27.0 0.36 T -68.6 -17.8