Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 55844532 . T A CCDS32450.1:NM_001025195.1:c.1215ttA>ttT_NP_001020366.1:p.405L>F Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mx1 1 P23141 99.82 0.0 X-RAY
 2003-04-22 LEU A:385 A:1404 0.0 0.0 H -96.0 -19.7 0.0 0.0 0.0 HOH
 3.470
 C
 O
LEU B:385 B:2404 0.0 0.0 H -106.1 -11.1 0.0 0.0 0.0 HOH
 3.579
 C
 O
LEU C:385 C:3404 0.0 0.0 H -99.6 -34.6 0.0 0.0 0.0 HOH
 3.518
 O
 O
LEU D:385 D:4404 1.0 0.006 H -102.4 -4.9 1.0 0.006 0.0 HOH
 3.962
 C
 O
LEU E:385 E:5404 0.0 0.0 H -99.2 -17.7 0.0 0.0 0.0 HOH
 3.420
 C
 O
LEU F:385 F:6404 0.0 0.0 H -92.5 -23.5 0.0 0.0 0.0 HOH
 4.453
 O
 O
1mx5 1 P23141 99.82 0.0 X-RAY
 2003-04-08 LEU A:385 A:1404 1.0 0.006 H -95.2 -3.9 1.0 0.006 0.0 HOH
 3.257
 O
 O
LEU B:385 B:2404 0.0 0.0 H -106.3 -24.9 0.0 0.0 0.0 HOH
 8.215
 O
 O
LEU C:385 C:3404 0.0 0.0 T -87.9 -27.8 0.0 0.0 0.0 HOH
 7.700
 O
 O
LEU D:385 D:4404 1.0 0.006 H -98.5 -25.0 NA NA NA
LEU E:385 E:5404 0.0 0.0 H -104.8 -18.7 NA NA NA
LEU F:385 F:6404 0.0 0.0 H -99.8 -17.0 NA NA NA
1mx9 1 P23141 99.82 0.0 X-RAY
 2003-04-08 LEU A:385 A:1404 0.0 0.0 H -100.4 9.9 0.0 0.0 0.0 HOH
 9.484
 CD2
 O
LEU B:385 B:2404 0.0 0.0 T -94.1 -27.4 0.0 0.0 0.0 HOH
 8.707
 C
 O
LEU C:385 C:3404 0.0 0.0 H -75.2 -48.9 0.0 0.0 0.0 HOH
 6.141
 O
 O
LEU D:385 D:4404 0.0 0.0 H -83.2 -34.8 0.0 0.0 0.0 HOH
 7.265
 O
 O
LEU E:385 E:5404 1.0 0.006 H -107.3 -7.1 1.0 0.006 0.0 HOH
 7.089
 O
 O
LEU F:385 F:6404 0.0 0.0 H -84.3 -1.4 0.0 0.0 0.0 HOH
 9.408
 O
 O
LEU G:385 G:1404 0.0 0.0 H -105.4 -0.5 NA NA NA
LEU H:385 H:2404 0.0 0.0 H -96.4 5.4 NA NA NA
LEU I:385 I:3404 0.0 0.0 H -107.2 2.3 NA NA NA
LEU J:385 J:4404 0.0 0.0 H -78.6 -27.2 NA NA NA
LEU K:385 K:5404 0.0 0.0 H -102.5 -23.2 NA NA NA
LEU L:385 L:6404 0.0 0.0 H -94.9 -12.3 NA NA NA
2dqy 1 P23141 99.82 0.0 X-RAY
 2006-08-29 LEU A:385 A:1404 1.0 0.006 H -90.3 -11.2 1.0 0.006 0.0 HOH
 8.221
 CD2
 O
LEU B:385 B:2404 1.0 0.006 H -89.2 -10.8 1.0 0.006 0.0 HOH
 8.066
 O
 O
LEU C:385 C:3404 1.0 0.006 H -90.0 -11.7 1.0 0.006 0.0 HOH
 4.281
 O
 O
2dqz 1 P23141 99.82 0.0 X-RAY
 2006-08-29 LEU A:385 A:1404 2.0 0.012 H -100.5 -4.9 2.0 0.012 0.0 HOH
 9.533
 O
 O
LEU B:385 B:2404 2.0 0.012 H -109.0 -2.8 2.0 0.012 0.0 HOH
 8.569
 N
 O
LEU C:385 C:3404 1.0 0.006 H -100.5 -7.4 1.0 0.006 0.0 HOH
 7.508
 CB
 O
2dr0 1 P23141 99.82 0.0 X-RAY
 2006-08-29 LEU A:385 A:1404 2.0 0.012 H -91.7 -31.1 2.0 0.012 0.0 HOH
 3.339
 O
 O
LEU B:385 B:2404 2.0 0.012 H -91.3 -31.3 2.0 0.012 0.0 HOH
 3.556
 O
 O
LEU C:385 C:3404 2.0 0.012 H -91.0 -31.7 2.0 0.012 0.0 HOH
 9.131
 O
 O
2h7c 1 P23141 99.82 0.0 X-RAY
 2006-08-29 LEU A:385 A:1404 0.0 0.0 H -95.2 -14.9 0.0 0.0 0.0 HOH
 4.903
 O
 O
LEU B:385 B:2404 0.0 0.0 H -101.9 -18.5 0.0 0.0 0.0 HOH
 3.276
 C
 O
LEU C:385 C:3404 0.0 0.0 H -100.5 -21.0 0.0 0.0 0.0 HOH
 3.395
 C
 O
LEU D:385 D:4404 0.0 0.0 T -97.9 -35.4 0.0 0.0 0.0 HOH
 4.028
 O
 O
LEU E:385 E:5404 0.0 0.0 H -105.8 -19.9 0.0 0.0 0.0 HOH
 3.392
 C
 O
LEU F:385 F:6404 0.0 0.0 H -100.6 -30.2 0.0 0.0 0.0 HOH
 7.215
 O
 O
1ya4 1 P23141 99.81 0.0 X-RAY
 2005-08-02 LEU A:383 A:404 2.0 0.012 H -92.7 -5.9 2.0 0.012 0.0
LEU B:383 B:404 2.0 0.012 H -92.5 -5.5 2.0 0.012 0.0 HOH
 8.390
 N
 O
LEU C:383 C:404 3.0 0.018 H -96.8 -8.3 3.0 0.018 0.0
1ya8 1 P23141 99.81 0.0 X-RAY
 2005-08-02 LEU A:383 A:404 2.0 0.012 H -74.8 -9.2 2.0 0.012 0.0 HOH
 7.281
 O
 O
LEU B:383 B:404 1.0 0.006 H -79.4 14.7 1.0 0.006 0.0 HOH
 8.339
 N
 O
LEU C:383 C:404 1.0 0.006 T -87.4 -4.4 1.0 0.006 0.0 HOH
 7.626
 O
 O
1yah 1 P23141 99.81 0.0 X-RAY
 2005-08-02 LEU A:383 A:404 1.0 0.006 H -83.7 -16.3 1.0 0.006 0.0 HOH
 6.428
 O
 O
LEU B:383 B:404 0.0 0.0 H -82.9 -14.6 0.0 0.0 0.0 HOH
 7.882
 CD1
 O
LEU C:383 C:404 1.0 0.006 H -85.2 -18.3 1.0 0.006 0.0 HOH
 8.786
 O
 O
1yaj 1 P23141 99.81 0.0 X-RAY
 2005-08-02 LEU A:383 A:404 2.0 0.012 H -88.2 -0.9 2.0 0.012 0.0
LEU B:383 B:404 1.0 0.006 H -76.2 -32.3 1.0 0.006 0.0
LEU C:383 C:404 3.0 0.018 T -108.8 -18.3 3.0 0.018 0.0
LEU D:383 D:404 2.0 0.012 H -124.1 -0.1 NA NA NA
LEU E:383 E:404 2.0 0.012 T -84.8 -16.0 NA NA NA
LEU F:383 F:404 2.0 0.012 H -81.1 -28.2 NA NA NA
LEU G:383 G:404 1.0 0.006 T -81.6 -17.2 NA NA NA
LEU H:383 H:404 1.0 0.006 H -76.4 15.3 NA NA NA
LEU I:383 I:404 1.0 0.006 H -80.3 -10.9 NA NA NA
LEU J:383 J:404 2.0 0.012 S -130.1 -11.3 NA NA NA
LEU K:383 K:404 0.0 0.0 H -81.4 2.5 NA NA NA
LEU L:383 L:404 0.0 0.0 H -90.9 -13.4 NA NA NA
2hrq 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 LEU A:383 A:1404 0.0 0.0 H -90.5 -27.2 0.0 0.0 0.0 HOH
 7.119
 O
 O
LEU B:383 B:2404 0.0 0.0 H -77.7 -30.3 0.0 0.0 0.0
LEU C:383 C:3404 0.0 0.0 H -98.5 -24.2 0.0 0.0 0.0 HOH
 3.496
 C
 O
LEU D:383 D:4404 0.0 0.0 H -98.0 -32.5 NA NA NA
LEU E:383 E:5404 0.0 0.0 H -78.5 -28.0 NA NA NA
LEU F:383 F:6404 0.0 0.0 H -95.4 -29.2 NA NA NA
2hrr 1 Q9UK77 99.81 0.0 X-RAY
 2007-05-01 LEU A:383 A:1404 0.0 0.0 I -91.0 -20.2 0.0 0.0 0.0 HOH
 8.744
 CD2
 O
LEU B:383 B:2404 0.0 0.0 H -100.4 -17.1 0.0 0.0 0.0 HOH
 3.305
 C
 O
LEU C:383 C:3404 0.0 0.0 H -91.3 -28.9 0.0 0.0 0.0 HOH
 3.749
 O
 O
4ab1 1 P23141 99.81 0.0 X-RAY
 2012-03-07 LEU A:383 A:404 0.0 0.0 H -106.3 -12.5 0.0 0.0 0.0 HOH
 7.169
 N
 O
5a7f 1 P23141-3 99.81 0.0 X-RAY
 2016-01-13 LEU A:383 A:403 0.0 0.0 H -106.1 -14.6 0.0 0.0 0.0 HOH
 3.401
 C
 O
5a7g 1 P23141 99.62 0.0 X-RAY
 2016-01-13 LEU A:383 A:403 0.0 0.0 H -105.7 -17.8 0.0 0.0 0.0 HOH
 3.387
 C
 O
5a7h 1 P23141 99.62 0.0 X-RAY
 2016-01-13 LEU A:382 A:403 0.0 0.0 H -105.6 -11.9 0.0 0.0 0.0 HOH
 4.086
 C
 O
3k9b 1 P23141 99.81 0.0 X-RAY
 2010-01-19 LEU A:380 A:1404 10.0 0.059 H -118.5 -4.1 10.0 0.059 0.0
LEU B:380 B:2404 15.0 0.088 H -120.3 -4.5 15.0 0.088 0.0
LEU C:380 C:3404 70.0 0.412 H -120.6 -4.8 70.0 0.412 0.0 HOH
 7.730
 CD1
 O
1k4y 1 3219695 82.06 0.0 X-RAY
 2002-05-01 LEU A:381 A:403 4.0 0.024 I -84.1 10.0 4.0 0.024 0.0 HOH
 5.712
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p23141-f1 1 P23141 99.82 0.0 LEU A:404 A:404 0.0 0.0 H -95.8 -17.8