Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr16 | 55844549 | . | C | A | CCDS32450.1:NM_001025195.1:c.1198Gcc>Tcc_NP_001020366.1:p.400A>S | Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1mx1 | 1 | P23141 | 99.82 | 0.0 |
X-RAY |
2003-04-22 | ALA | A:380 | A:1399 | 0.0 | 0.0 | H | -61.1 | -45.2 | 0.0 | 0.0 | 0.0 |
HOH |
4.722 |
N |
O |
||
| ALA | B:380 | B:2399 | 0.0 | 0.0 | H | -60.3 | -47.0 | 0.0 | 0.0 | 0.0 |
HOH |
5.112 |
N |
O |
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| ALA | C:380 | C:3399 | 0.0 | 0.0 | H | -62.8 | -45.1 | 0.0 | 0.0 | 0.0 |
HOH |
5.127 |
N |
O |
|||||||||
| ALA | D:380 | D:4399 | 0.0 | 0.0 | H | -65.9 | -48.2 | 0.0 | 0.0 | 0.0 |
HOH |
4.962 |
N |
O |
|||||||||
| ALA | E:380 | E:5399 | 0.0 | 0.0 | H | -57.2 | -50.1 | 0.0 | 0.0 | 0.0 |
HOH |
4.850 |
N |
O |
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| ALA | F:380 | F:6399 | 0.0 | 0.0 | H | -52.3 | -52.3 | 0.0 | 0.0 | 0.0 |
HOH |
5.467 |
N |
O |
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| 1mx5 | 1 | P23141 | 99.82 | 0.0 |
X-RAY |
2003-04-08 | ALA | A:380 | A:1399 | 0.0 | 0.0 | H | -64.8 | -59.3 | 0.0 | 0.0 | 0.0 |
HOH |
5.145 |
N |
O |
||
| ALA | B:380 | B:2399 | 0.0 | 0.0 | H | -59.2 | -58.0 | 0.0 | 0.0 | 0.0 |
HOH |
4.846 |
N |
O |
|||||||||
| ALA | C:380 | C:3399 | 0.0 | 0.0 | H | -48.8 | -57.7 | 0.0 | 0.0 | 0.0 |
HOH |
5.080 |
N |
O |
|||||||||
| ALA | D:380 | D:4399 | 0.0 | 0.0 | H | -68.3 | -50.2 | NA | NA | NA | |||||||||||||
| ALA | E:380 | E:5399 | 0.0 | 0.0 | H | -62.8 | -54.2 | NA | NA | NA | |||||||||||||
| ALA | F:380 | F:6399 | 0.0 | 0.0 | H | -54.2 | -65.0 | NA | NA | NA | |||||||||||||
| 1mx9 | 1 | P23141 | 99.82 | 0.0 |
X-RAY |
2003-04-08 | ALA | A:380 | A:1399 | 0.0 | 0.0 | H | -72.6 | -43.7 | 0.0 | 0.0 | 0.0 |
HOH |
8.669 |
CB |
O |
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| ALA | B:380 | B:2399 | 0.0 | 0.0 | H | -68.2 | -33.4 | 0.0 | 0.0 | 0.0 |
HOH |
5.544 |
N |
O |
|||||||||
| ALA | C:380 | C:3399 | 0.0 | 0.0 | H | -66.7 | -41.0 | 0.0 | 0.0 | 0.0 |
HOH |
8.342 |
CB |
O |
|||||||||
| ALA | D:380 | D:4399 | 0.0 | 0.0 | H | -56.8 | -57.4 | 0.0 | 0.0 | 0.0 |
HOH |
7.824 |
O |
O |
|||||||||
| ALA | E:380 | E:5399 | 0.0 | 0.0 | H | -56.2 | -55.0 | 0.0 | 0.0 | 0.0 |
HOH |
8.072 |
CB |
O |
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| ALA | F:380 | F:6399 | 0.0 | 0.0 | H | -70.3 | -48.8 | 0.0 | 0.0 | 0.0 |
HOH |
5.434 |
N |
O |
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| ALA | G:380 | G:1399 | 0.0 | 0.0 | H | -90.6 | -38.1 | NA | NA | NA | |||||||||||||
| ALA | H:380 | H:2399 | 0.0 | 0.0 | H | -59.5 | -56.2 | NA | NA | NA | |||||||||||||
| ALA | I:380 | I:3399 | 0.0 | 0.0 | H | -50.2 | -52.8 | NA | NA | NA | |||||||||||||
| ALA | J:380 | J:4399 | 0.0 | 0.0 | H | -61.9 | -40.1 | NA | NA | NA | |||||||||||||
| ALA | K:380 | K:5399 | 0.0 | 0.0 | H | -74.4 | -43.2 | NA | NA | NA | |||||||||||||
| ALA | L:380 | L:6399 | 0.0 | 0.0 | H | -70.4 | -50.3 | NA | NA | NA | |||||||||||||
| 2dqy | 1 | P23141 | 99.82 | 0.0 |
X-RAY |
2006-08-29 | ALA | A:380 | A:1399 | 0.0 | 0.0 | H | -55.9 | -51.9 | 0.0 | 0.0 | 0.0 |
HOH |
4.690 |
N |
O |
||
| ALA | B:380 | B:2399 | 0.0 | 0.0 | H | -56.2 | -51.3 | 0.0 | 0.0 | 0.0 | |||||||||||||
| ALA | C:380 | C:3399 | 0.0 | 0.0 | H | -57.5 | -51.0 | 0.0 | 0.0 | 0.0 |
HOH |
4.701 |
N |
O |
|||||||||
| 2dqz | 1 | P23141 | 99.82 | 0.0 |
X-RAY |
2006-08-29 | ALA | A:380 | A:1399 | 0.0 | 0.0 | H | -52.1 | -48.8 | 0.0 | 0.0 | 0.0 |
HOH |
8.547 |
CB |
O |
||
| ALA | B:380 | B:2399 | 0.0 | 0.0 | H | -59.6 | -45.5 | 0.0 | 0.0 | 0.0 |
HOH |
4.637 |
N |
O |
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| ALA | C:380 | C:3399 | 0.0 | 0.0 | H | -63.4 | -48.0 | 0.0 | 0.0 | 0.0 |
HOH |
4.907 |
N |
O |
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| 2dr0 | 1 | P23141 | 99.82 | 0.0 |
X-RAY |
2006-08-29 | ALA | A:380 | A:1399 | 0.0 | 0.0 | H | -67.3 | -46.7 | 0.0 | 0.0 | 0.0 |
HOH |
7.584 |
O |
O |
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| ALA | B:380 | B:2399 | 0.0 | 0.0 | H | -66.5 | -47.7 | 0.0 | 0.0 | 0.0 |
HOH |
8.628 |
CB |
O |
|||||||||
| ALA | C:380 | C:3399 | 0.0 | 0.0 | H | -66.3 | -46.6 | 0.0 | 0.0 | 0.0 |
HOH |
6.206 |
N |
O |
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| 2h7c | 1 | P23141 | 99.82 | 0.0 |
X-RAY |
2006-08-29 | ALA | A:380 | A:1399 | 0.0 | 0.0 | H | -60.8 | -51.0 | 0.0 | 0.0 | 0.0 |
HOH |
5.000 |
N |
O |
||
| ALA | B:380 | B:2399 | 0.0 | 0.0 | H | -53.5 | -46.5 | 0.0 | 0.0 | 0.0 |
HOH |
4.903 |
N |
O |
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| ALA | C:380 | C:3399 | 0.0 | 0.0 | H | -60.1 | -44.8 | 0.0 | 0.0 | 0.0 |
HOH |
4.888 |
N |
O |
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| ALA | D:380 | D:4399 | 0.0 | 0.0 | H | -64.2 | -48.2 | 0.0 | 0.0 | 0.0 |
HOH |
4.842 |
N |
O |
|||||||||
| ALA | E:380 | E:5399 | 0.0 | 0.0 | H | -58.9 | -45.2 | 0.0 | 0.0 | 0.0 |
HOH |
4.677 |
N |
O |
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| ALA | F:380 | F:6399 | 0.0 | 0.0 | H | -58.1 | -49.3 | 0.0 | 0.0 | 0.0 |
HOH |
4.754 |
N |
O |
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| 1ya4 | 1 | P23141 | 99.81 | 0.0 |
X-RAY |
2005-08-02 | ALA | A:378 | A:399 | 0.0 | 0.0 | H | -86.5 | -43.4 | 0.0 | 0.0 | 0.0 | ||||||
| ALA | B:378 | B:399 | 0.0 | 0.0 | H | -83.0 | -46.5 | 0.0 | 0.0 | 0.0 |
HOH |
9.164 |
N |
O |
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| ALA | C:378 | C:399 | 0.0 | 0.0 | H | -81.1 | -47.3 | 0.0 | 0.0 | 0.0 |
HOH |
8.775 |
CB |
O |
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| 1ya8 | 1 | P23141 | 99.81 | 0.0 |
X-RAY |
2005-08-02 | ALA | A:378 | A:399 | 0.0 | 0.0 | H | -65.4 | -55.9 | 0.0 | 0.0 | 0.0 | ||||||
| ALA | B:378 | B:399 | 0.0 | 0.0 | H | -68.8 | -52.6 | 0.0 | 0.0 | 0.0 |
HOH |
4.816 |
N |
O |
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| ALA | C:378 | C:399 | 0.0 | 0.0 | H | -63.1 | -51.2 | 0.0 | 0.0 | 0.0 |
HOH |
7.352 |
N |
O |
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| 1yah | 1 | P23141 | 99.81 | 0.0 |
X-RAY |
2005-08-02 | ALA | A:378 | A:399 | 0.0 | 0.0 | H | -59.8 | -55.9 | 0.0 | 0.0 | 0.0 |
HOH |
7.445 |
O |
O |
||
| ALA | B:378 | B:399 | 0.0 | 0.0 | H | -59.2 | -54.9 | 0.0 | 0.0 | 0.0 |
HOH |
5.933 |
N |
O |
|||||||||
| ALA | C:378 | C:399 | 0.0 | 0.0 | H | -61.8 | -52.7 | 0.0 | 0.0 | 0.0 |
HOH |
7.471 |
N |
O |
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| 1yaj | 1 | P23141 | 99.81 | 0.0 |
X-RAY |
2005-08-02 | ALA | A:378 | A:399 | 0.0 | 0.0 | H | -69.9 | -55.8 | 0.0 | 0.0 | 0.0 | ||||||
| ALA | B:378 | B:399 | 0.0 | 0.0 | H | -70.9 | -60.4 | 0.0 | 0.0 | 0.0 |
HOH |
8.599 |
N |
O |
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| ALA | C:378 | C:399 | 0.0 | 0.0 | H | -78.1 | -32.0 | 0.0 | 0.0 | 0.0 | |||||||||||||
| ALA | D:378 | D:399 | 0.0 | 0.0 | H | -68.2 | -47.8 | NA | NA | NA | |||||||||||||
| ALA | E:378 | E:399 | 0.0 | 0.0 | H | -64.9 | -60.1 | NA | NA | NA | |||||||||||||
| ALA | F:378 | F:399 | 0.0 | 0.0 | H | -79.3 | -52.3 | NA | NA | NA | |||||||||||||
| ALA | G:378 | G:399 | 0.0 | 0.0 | H | -83.9 | -32.4 | NA | NA | NA | |||||||||||||
| ALA | H:378 | H:399 | 0.0 | 0.0 | H | -51.8 | -48.1 | NA | NA | NA | |||||||||||||
| ALA | I:378 | I:399 | 0.0 | 0.0 | H | -66.6 | -57.0 | NA | NA | NA | |||||||||||||
| ALA | J:378 | J:399 | 0.0 | 0.0 | H | -77.4 | -21.2 | NA | NA | NA | |||||||||||||
| ALA | K:378 | K:399 | 0.0 | 0.0 | H | -47.8 | -55.0 | NA | NA | NA | |||||||||||||
| ALA | L:378 | L:399 | 0.0 | 0.0 | H | -72.6 | -65.3 | NA | NA | NA | |||||||||||||
| 2hrq | 1 | Q9UK77 | 99.81 | 0.0 |
X-RAY |
2007-05-01 | ALA | A:378 | A:1399 | 0.0 | 0.0 | H | -52.2 | -43.0 | 0.0 | 0.0 | 0.0 |
HOH |
8.455 |
N |
O |
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| ALA | B:378 | B:2399 | 0.0 | 0.0 | H | -79.7 | -48.8 | 0.0 | 0.0 | 0.0 |
HOH |
8.658 |
CB |
O |
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| ALA | C:378 | C:3399 | 0.0 | 0.0 | H | -64.2 | -53.7 | 0.0 | 0.0 | 0.0 |
HOH |
5.246 |
N |
O |
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| ALA | D:378 | D:4399 | 0.0 | 0.0 | H | -56.2 | -53.9 | NA | NA | NA | |||||||||||||
| ALA | E:378 | E:5399 | 0.0 | 0.0 | H | -84.4 | -44.4 | NA | NA | NA | |||||||||||||
| ALA | F:378 | F:6399 | 0.0 | 0.0 | H | -55.9 | -55.7 | NA | NA | NA | |||||||||||||
| 2hrr | 1 | Q9UK77 | 99.81 | 0.0 |
X-RAY |
2007-05-01 | ALA | A:378 | A:1399 | 0.0 | 0.0 | H | -59.5 | -55.9 | 0.0 | 0.0 | 0.0 |
HOH |
4.803 |
N |
O |
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| ALA | B:378 | B:2399 | 0.0 | 0.0 | H | -74.6 | -49.2 | 0.0 | 0.0 | 0.0 |
HOH |
2.519 |
N |
O |
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| ALA | C:378 | C:3399 | 0.0 | 0.0 | H | -61.6 | -54.1 | 0.0 | 0.0 | 0.0 |
HOH |
4.953 |
N |
O |
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| 4ab1 | 1 | P23141 | 99.81 | 0.0 |
X-RAY |
2012-03-07 | ALA | A:378 | A:399 | 0.0 | 0.0 | H | -52.8 | -53.5 | 0.0 | 0.0 | 0.0 |
HOH |
4.775 |
N |
O |
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| 5a7f | 1 | P23141-3 | 99.81 | 0.0 |
X-RAY |
2016-01-13 | ALA | A:378 | A:398 | 0.0 | 0.0 | H | -59.0 | -44.9 | 0.0 | 0.0 | 0.0 |
HOH |
6.276 |
N |
O |
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| 5a7g | 1 | P23141 | 99.62 | 0.0 |
X-RAY |
2016-01-13 | ALA | A:378 | A:398 | 0.0 | 0.0 | H | -64.4 | -47.7 | 0.0 | 0.0 | 0.0 |
HOH |
4.764 |
N |
O |
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| 5a7h | 1 | P23141 | 99.62 | 0.0 |
X-RAY |
2016-01-13 | ALA | A:377 | A:398 | 0.0 | 0.0 | H | -57.2 | -49.4 | 0.0 | 0.0 | 0.0 |
HOH |
5.011 |
N |
O |
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| 3k9b | 1 | P23141 | 99.81 | 0.0 |
X-RAY |
2010-01-19 | ALA | A:375 | A:1399 | 4.0 | 0.035 | H | -65.7 | -56.5 | 4.0 | 0.035 | 0.0 |
HOH |
9.684 |
CB |
O |
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| ALA | B:375 | B:2399 | 3.0 | 0.026 | H | -66.2 | -56.6 | 3.0 | 0.026 | 0.0 |
HOH |
8.398 |
N |
O |
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| ALA | C:375 | C:3399 | 13.0 | 0.113 | H | -66.3 | -57.8 | 13.0 | 0.113 | 0.0 |
HOH |
5.877 |
C |
O |
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| 1k4y | 1 | 3219695 | 82.06 | 0.0 |
X-RAY |
2002-05-01 | ALA | A:376 | A:398 | 0.0 | 0.0 | H | -48.8 | -48.7 | 0.0 | 0.0 | 0.0 |
HOH |
7.180 |
O |
O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p23141-f1 | 1 | P23141 | 99.82 | 0.0 | ALA | A:399 | A:399 | 0.0 | 0.0 | H | -59.7 | -50.0 | |